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Your Environment. Your Health.

Epidemiology and Biomarkers of Parkinsonism in Welders

Grant Number:
Principal Investigator:
Racette, Brad A
Washington University
Most Recent Award Year:
Lifestage of Participants:
Exposure: Adulthood (18+ years)
Assessment: Adulthood (18+ years)
Metals: Manganese
Health Outcomes:
Neurological / Cognitive Outcomes: Parkinson's disease
Biological Sample:
Other Participant Data:
Questionnaire to reconstruct participant welding exposure; Job Exposure Matrix (JEM) to determine dose-response relationship; Standardized neurologic examinations and timed motor tasks

Related NIEHS-Funded Study Populations

Parkinsonism and Metal Exposures Among Welders

Principal Investigator:
Racette, Brad; Checkoway, Harvey | Study Population Page Study Population c116
Washington University
Number of Participants::
875 welders and 200 controls
Brief Description::
This is an occupational cohort study examining how exposure to manganese and other metals affects the risk, severity, and progression of Parkinsonism and Parkinson’s disease among professional welders. Since 2005, the study has enrolled 875 Wisconsin shipyard welders (775 actively employed, 100 retired) and 200 non-exposed shipyard workers.
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