Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Your Environment. Your Health.

Details

Back to List

2004

Glucocorticoids and Tumor Necrosis Factor Alpha Play Unique Role in Regulating Inflammation

inflammation inside human body

Researchers identified a unique cooperative role for certain hormones and proteins in the body, specifically glucocorticoids and tumor necrosis factor alpha, in regulating adaptive immunity and inflammation. Inflammation has been implicated as a contributing factor in several human cancers, including lung cancer. These results have important implications for immune responses to agents like bacterial lipopolysaccharides and numerous other environmental agents.

Tags: cancer, immune, inflammation, lung

Citation:

Hermoso MA, Matsuguchi T, Smoak K, Cidlowski JA. 2004. Glucocorticoids and tumor necrosis factor alpha cooperatively regulate toll-like receptor 2 gene expression. Mol Cell Biol. 24(11):4743-4756.

More Information:

NIEHS Program:

NIEHS Research Funding:

Back
to Top