Red Tide Compounds May Treat Cystic Fibrosis
NIEHS-funded researchers discovered two new compounds derived from red tide that may treat mucus buildup associated with cystic fibrosis and similar lung diseases. Preliminary studies show these compounds improve the flow of mucus through the respiratory tract, allowing airways to clear more quickly and efficiently. These compounds offer new targets for the development of medications to help patients with cystic fibrosis and for individuals who may be affected during episodes of red tide algal blooms.
Abraham WM, Bourdelais AJ, Sabater JR, Ahmed A, Lee TA, Serebriakov I, Baden DG. 2005. Airway responses to aerosolized brevetoxins in an animal model of asthma. Am J Respir Crit Care Med 171(1):26-34. [Abstract] [Full Text]
NIEHS Research Funding:
- 2004: Research with Red Tide Toxin Yields Potential Therapies for Cystic Fibrosis