Toxin Destroys Macrophages, Enabling Anthrax to Invade Host
NIEHS-supported children's health researchers at the University of California at San Diego discovered that B. anthrax evades the host immune system, using a toxin called lethal factor to destroy macrophages and spread throughout the body. These results may explain why anthrax infections proceed nearly undetected until the patient is very sick and near death.
NIEHS Research Funding:
- 2002: Molecular Mechanism Underlying Anthrax Infection Described by NIEHS-Funded Researchers