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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

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2001

Environmental Autoimmunity Group Established at NIH Clinical Center in Bethesda, Md.

front and side view of human skeleton areas highlighted in red

NIEHS established a presence at the NIH Clinical Center with the Environmental Autoimmunity Group. Researchers are studying the mechanisms involved in the development of autoimmune diseases as well as genetic and environmental factors. Research focuses on systemic rheumatic diseases such as rheumatoid arthritis, systemic lupas erythematosus, scleroderma and idiopathic inflammatory myopathies - diseases marked by chronic inflammation. EAG studies also focus on developing clinical tools and innovative therapies for the diagnosis and treatment of these diseases.

Tags: Autoimmunity, bethesda

Citation:

Javierre BM, Fernandez AF, Richter J, Al-Shahrour F, Martin-Subero JI, Rodriguez-Ubreva J, Berdasco M, Fraga MF, O'Hanlon TP, Rider LG, Jacinto FV, Lopez-Longo FJ, Dopazo J, Forn M, Peinado MA, Carreño L, Sawalha AH, Harley JB, Siebert R, Esteller M, Miller FW, Ballestar E. 2010. Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus. Genome Res 20(2):170-179. [Abstract]   [PDF]   [Full Text]  

Huber AM, Giannini EH, Bowyer SL, Kim S, Lang B, Lindsley CB, Pachman LM, Pilkington C, Reed AM, Rennebohm RM, Rider LG, Wallace CA, Feldman BM. 2010. Protocols for the initial treatment of moderately severe juvenile dermatomyositis: Results of a Children's Arthritis and Rheumatology Research Alliance Consensus Conference.  Arthritis Care Res (Hoboken). 62(2):219-225. [Abstract]   [PDF]   [Full Text]  

Rider LG, Kziol D, Giannini EH, Jain MS, Smith MR, Whitney-Mahoney K, Feldman BM, Wright SJ, Lindsley CB, Pachman LM, Villalba ML, Lovell DJ, Bowyer SL, Plotz PH, Miller FW, Hicks JE. 2010. Validation of manual muscle testing and a subset of eight muscles for adult and juvenile idiopathic inflammatory myopathies. Arthritis Care Res (Hoboken) 62(4):465-472. [Abstract]

More Information:

NIEHS Programs:

News Releases:

  • 2009: Sun Exposure May Trigger Certain Autoimmune Diseases in Women
  • 2001: NIEHS Initiates Clinical Center Research Group to Study and Treat Autoimmune Muscle Disorders

Environmental Health Perspectives Article:

Environmental Factor articles:

Other:

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