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Beta-amyloid Peptide Can Disrupt Brain Signals in Alzheimer's Disease

nurse kneeling and assisting elderly woman in wheelchair

NIEHS scientists discovered that beta-amyloid peptide, found in patients with Alzheimer's disease, can disrupt brain signals that may contribute to the memory loss associated with Alzheimer's disease.

Tags: alzheimer's, brain, peptide


Pettit DL, Shao Z, Yakel JL. 2001. Beta-amyloid(1-42) peptide directly modulates nicotinic receptors in the rat hippocampal slice. J Neurosci 21(1):RC120. [Abstract] [Full Text]

More Information:

News Releases:

    • 2010: Targeting the Blood-Brain Barrier May Delay Progression of Alzheimer’s Disease
    • 2001: Environmental Health Institute Scientists Begin to Unravel Cause of Blocked Memory in Alzheimer's

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