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Researchers ID Mechanism for Aflatoxin to Cause Liver Cancer

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NIEHS-funded researchers identified the mechanism by which aflatoxin, a toxin produced by fungus found on corn, peanuts, and other crops in Africa and Asia, causes liver cancer.

Tags: cancer


Wang JS, Shen X, He X, Zhu YR, Zhang BC, Wang JB, Qian GS, Kuang SY, Zarba A, Egner PA, Jacobson LP, Munoz A, Helzlsouer KJ, Groopman JD, Kensler TW. Protective alterations in phase 1 and 2 metabolism of aflatoxin B1 by oltipraz in residents of Qidong, People's Republic of China. J Natl Cancer Inst 91(4):347-354. [Abstract] [Full Text]

Wogan GN. 1999. Aflatoxin as a human carcinogen. Hepatology (2):573-575. [Abstract] [PDF]

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