OECD Guidance Documents and Test Guidelines

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No. Title Publication Date Notice Number Link
1 OECD Series on Principles of Good Laboratory Practice and Compliance Monitoring Number 1: OECD Principles on GLP 01-26-1998 GD 1 PDF
2 OECD Guidance Document 125: Histopathology for Subacute and Subchronic Inhalation Toxicity Studies 06-01-2010 GD 125 PDF
3 OECD Series on Testing and Assessment No. 126: Short Guidance on the Threshold Approach for Acute Fish Toxicity 05-31-2010 GD 126 PDF
4 OECD Guidance Document 160: The BCOP and ICE Test Methods: Collection of Tissues for Histological Evaluation and Collection of Data on Non-severe Irritants 10-25-2011 GD 160 PDF
5 OECD Guidance Document 19: Recognition, Assessment and Use of Clinical Signs as Humane Endpoints for Experimental Animals Used in Safety Evaluation 11-01-2000 GD 19 PDF
6 OECD Series on Testing and Assessment No. 203: New Guidance Document on an Integrated Approach on Testing and Assessment (IATA) for Skin Corrosion and Irritation 07-11-2014 GD 203 PDF
7 OECD Guidance Document 211: Guidance Document for Describing Non-Guideline In Vitro Test Methods 12-15-2014 GD 211 PDF
8 OECD Guidance Document 24: Acute Oral Toxicity Testing 07-23-2001 GD 24 PDF
9 OECD Guidance Document 33: Harmonised Integrated Classification System for Human Health and Environmental Hazards of Chemical Substances and Mixtures 08-14-2001 GD 33 PDF
10 OECD Guidance Document 34: Validation and International Acceptance of New or Updated Internationally Acceptable Test Methods for Hazard Assessment 08-18-2005 GD 34 PDF
11 OECD Guidance Document 39: Acute Inhalation Toxicity Testing 07-21-2009 GD 39 PDF
12 OECD Series on Principles of Good Laboratory Practice and Compliance Monitoring Number 14 - The Application of the Principles of GLP to in vitro Studies 11-30-2004 GLP14 PDF
13 OECD Test Guideline 223: Avian Acute Oral Toxicity Test 07-22-2010 TG 223 PDF
14 OECD Test Guideline 403: Acute Inhalation Toxicity 09-07-2009 TG 403 PDF
15 OECD Test Guideline 404: Acute Dermal Irritation/Corrosion 04-24-2002 TG 404 PDF
16 OECD Test Guideline 405: Acute Eye Irritation/Corrosion (updated 2012) 04-24-2002 TG 405 PDF
17 OECD Test Guideline 406: Skin Sensitization 07-17-1992 TG 406 PDF
18 OECD Test Guideline 407: Repeated 28-day Oral Toxicity Study in Rodents 10-03-2008 TG 407 PDF
19 OECD Test Guideline 412: Subacute Inhalation Toxicity: 28-day Study 09-07-2009 TG 412 PDF
20 OECD Test Guideline 413: Subchronic Inhalation Toxicity: 90-day Study 09-07-2009 TG 413 PDF
21 OECD Test Guideline 414: Prenatal Development Toxicity Study 01-22-2001 TG 414 PDF
22 OECD Test Guideline 420: Acute Oral Toxicity - Fixed Dose Procedure 12-17-2001 TG 420 PDF
23 OECD Test Guideline 421: Reproduction/Developmental Toxicity Screening Test 07-27-1995 TG 421 PDF
24 OECD Test Guideline 422: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test 03-22-1996 TG 422 PDF
25 OECD Test Guideline 423: Acute Oral toxicity - Acute Toxic Class Method 12-17-2001 TG 423 PDF
26 OECD Test Guideline 425: Acute Oral Toxicity - Up-and-Down Procedure (UDP) 03-23-2006 TG 425 PDF
27 OECD Test Guideline 428: Skin Absorption In Vitro Method 04-13-2004 TG 428 PDF
28 OECD Test Guideline 429: Skin Sensitisation: Local Lymph Node Assay 07-22-2010 TG 429 PDF
29 OECD Test Guideline 430: In Vitro Skin Corrosion: Transcutaneous Electrical Resistance Test (TER) 07-26-2013 TG 430 PDF
30 OECD Test Guideline 431: In Vitro Skin Corrosion: Reconstructed Human Epidermis (RHE) Test Method 09-26-2014 TG 431 PDF
31 OECD Test Guideline 432: In Vitro 3T3 NRU Phototoxicity Test 04-13-2004 TG 432 PDF
32 OECD Test Guideline 435: In Vitro Membrane Barrier Test Method for Skin Corrosion 07-19-2006 TG 435 PDF
33 OECD Test Guideline 436: Acute Inhalation Toxicity - Acute Toxic Class Method 09-07-2009 TG 436 PDF
34 OECD Test Guideline 437: Bovine Corneal Opacity and Permeability Test Method i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage 07-26-2013 TG 437 PDF
35 OECD Test Guideline 438: Isolated Chicken Eye Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage 07-26-2013 TG 438 PDF
36 OECD Test Guideline 439: In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method 07-26-2013 TG 439 PDF
37 OECD Test Guideline 440: Uterotrophic Bioassay in Rodents: A short-term screening test for oestrogenic properties 10-16-2007 TG 440 PDF
38 OECD Test Guideline 441: Hershberger Bioassay in Rats: A Short-term Screening Assay for (Anti)Androgenic Properties 09-07-2009 TG 441 PDF
39 OECD Test Guideline 442A: Skin Sensitization: Local Lymph Node Assay: DA 07-22-2010 TG 442A PDF
40 OECD Test Guideline 442B: Skin Sensitization: Local Lymph Node Assay: BrdU-ELISA 07-22-2010 TG 442B PDF
41 OECD Test Guideline 442C: In Chemico Skin Sensitisation: Direct Peptide Reactivity Assay 02-04-2015 TG 442C PDF
42 OECD Test Guideline 442D: In Vitro Skin Sensitisation: ARE-Nrf2 Luciferase Test Method 02-04-2015 TG 442D PDF
43 OECD Test Guideline 443: Extended One-Generation Reproductive Toxicity Study 10-02-2012 TG 443 PDF
44 OECD Test Guideline 455: Performance-Based Test Guideline for Stably Transfected Transactivation In Vitro Assays to Detect Estrogen Receptor Agonists (updated 2012) 09-07-2009 TG 455 PDF
45 OECD Test Guideline 457: BG1Luc Estrogen Receptor Transactivation Test Method for Identifying Estrogen Receptor Agonists and Antagonists 10-02-2012 TG 457 PDF
46 OECD Test Guideline 460: Fluorescein Leakage Test Method for Identifying Ocular Corrosives and Severe Irritants 10-02-2012 TG 460 PDF
47 OECD Test Guideline 473: In Vitro Mammalian Chromosomal Aberration Test 09-26-2014 TG 473 PDF
48 OECD Test Guideline 487: In Vitro Mammalian Cell Micronucleus Test 09-28-2014 TG 487 PDF
49 OECD Test Guideline 489: In Vivo Mammalian Alkaline Comet Assay 09-26-2014 TG 489 PDF
50 OECD Test Guideline 456: H295R Steroidogenesis Assay 07-28-2011 TG456 PDF

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