OECD Guidance Documents and Test Guidelines

Site Map
Site Map

No. Title Publication Date Notice Number Link
1 OECD Series on Principles of Good Laboratory Practice and Compliance Monitoring Number 1: OECD Principles on GLP 01-26-1998 GD 1 PDF
2 OECD Guidance Document 125: Histopathology for Subacute and Subchronic Inhalation Toxicity Studies 06-01-2010 GD 125 PDF
3 OECD Series on Testing and Assessment No. 126: Short Guidance on the Threshold Approach for Acute Fish Toxicity 05-31-2010 GD 126 PDF
4 OECD Guidance Document 160: The BCOP and ICE Test Methods: Collection of Tissues for Histological Evaluation and Collection of Data on Non-severe Irritants 10-25-2011 GD 160 PDF
5 OECD Guidance Document 19: Recognition, Assessment and Use of Clinical Signs as Humane Endpoints for Experimental Animals Used in Safety Evaluation 11-01-2000 GD 19 PDF
6 OECD Series on Testing and Assessment No. 203: New Guidance Document on an Integrated Approach on Testing and Assessment (IATA) for Skin Corrosion and Irritation 07-11-2014 GD 203 PDF
7 OECD Guidance Document 211: Guidance Document for Describing Non-Guideline In Vitro Test Methods 12-15-2014 GD 211 PDF
8 OECD Guidance Document 24: Acute Oral Toxicity Testing 07-23-2001 GD 24 PDF
9 OECD Guidance Document 33: Harmonised Integrated Classification System for Human Health and Environmental Hazards of Chemical Substances and Mixtures 08-14-2001 GD 33 PDF
10 OECD Guidance Document 34: Validation and International Acceptance of New or Updated Internationally Acceptable Test Methods for Hazard Assessment 08-18-2005 GD 34 PDF
11 OECD Guidance Document 39: Acute Inhalation Toxicity Testing 07-21-2009 GD 39 PDF
12 OECD Series on Principles of Good Laboratory Practice and Compliance Monitoring Number 14 - The Application of the Principles of GLP to in vitro Studies 11-30-2004 GLP14 PDF
13 OECD Test Guideline 223: Avian Acute Oral Toxicity Test 07-22-2010 TG 223 PDF
14 OECD Test Guideline 403: Acute Inhalation Toxicity 09-07-2009 TG 403 PDF
15 OECD Test Guideline 404: Acute Dermal Irritation/Corrosion 04-24-2002 TG 404 PDF
16 OECD Test Guideline 405: Acute Eye Irritation/Corrosion (updated 2012) 04-24-2002 TG 405 PDF
17 OECD Test Guideline 406: Skin Sensitization 07-17-1992 TG 406 PDF
18 OECD Test Guideline 407: Repeated 28-day Oral Toxicity Study in Rodents 10-03-2008 TG 407 PDF
19 OECD Test Guideline 412: Subacute Inhalation Toxicity: 28-day Study 09-07-2009 TG 412 PDF
20 OECD Test Guideline 413: Subchronic Inhalation Toxicity: 90-day Study 09-07-2009 TG 413 PDF
21 OECD Test Guideline 414: Prenatal Development Toxicity Study 01-22-2001 TG 414 PDF
22 OECD Test Guideline 420: Acute Oral Toxicity - Fixed Dose Procedure 12-17-2001 TG 420 PDF
23 OECD Test Guideline 421: Reproduction/Developmental Toxicity Screening Test 07-27-1995 TG 421 PDF
24 OECD Test Guideline 422: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test 03-22-1996 TG 422 PDF
25 OECD Test Guideline 423: Acute Oral toxicity - Acute Toxic Class Method 12-17-2001 TG 423 PDF
26 OECD Test Guideline 425: Acute Oral Toxicity - Up-and-Down Procedure (UDP) 03-23-2006 TG 425 PDF
27 OECD Test Guideline 428: Skin Absorption In Vitro Method 04-13-2004 TG 428 PDF
28 OECD Test Guideline 429: Skin Sensitisation: Local Lymph Node Assay 07-22-2010 TG 429 PDF
29 OECD Test Guideline 430: In Vitro Skin Corrosion: Transcutaneous Electrical Resistance Test (TER) 07-26-2013 TG 430 PDF
30 OECD Test Guideline 431: In Vitro Skin Corrosion: Reconstructed Human Epidermis (RHE) Test Method 09-26-2014 TG 431 PDF
31 OECD Test Guideline 432: In Vitro 3T3 NRU Phototoxicity Test 04-13-2004 TG 432 PDF
32 OECD Test Guideline 435: In Vitro Membrane Barrier Test Method for Skin Corrosion 07-19-2006 TG 435 PDF
33 OECD Test Guideline 436: Acute Inhalation Toxicity - Acute Toxic Class Method 09-07-2009 TG 436 PDF
34 OECD Test Guideline 437: Bovine Corneal Opacity and Permeability Test Method i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage 07-26-2013 TG 437 PDF
35 OECD Test Guideline 438: Isolated Chicken Eye Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage 07-26-2013 TG 438 PDF
36 OECD Test Guideline 439: In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method 07-26-2013 TG 439 PDF
37 OECD Test Guideline 440: Uterotrophic Bioassay in Rodents: A short-term screening test for oestrogenic properties 10-16-2007 TG 440 PDF
38 OECD Test Guideline 441: Hershberger Bioassay in Rats: A Short-term Screening Assay for (Anti)Androgenic Properties 09-07-2009 TG 441 PDF
39 OECD Test Guideline 442A: Skin Sensitization: Local Lymph Node Assay: DA 07-22-2010 TG 442A PDF
40 OECD Test Guideline 442B: Skin Sensitization: Local Lymph Node Assay: BrdU-ELISA 07-22-2010 TG 442B PDF
41 OECD Test Guideline 442C: In Chemico Skin Sensitisation: Direct Peptide Reactivity Assay 02-04-2015 TG 442C PDF
42 OECD Test Guideline 442D: In Vitro Skin Sensitisation: ARE-Nrf2 Luciferase Test Method 02-04-2015 TG 442D PDF
43 OECD Test Guideline 443: Extended One-Generation Reproductive Toxicity Study 10-02-2012 TG 443 PDF
44 OECD Test Guideline 455: Performance-Based Test Guideline for Stably Transfected Transactivation In Vitro Assays to Detect Estrogen Receptor Agonists (updated 2012) 09-07-2009 TG 455 PDF
45 OECD Test Guideline 457: BG1Luc Estrogen Receptor Transactivation Test Method for Identifying Estrogen Receptor Agonists and Antagonists 10-02-2012 TG 457 PDF
46 OECD Test Guideline 460: Fluorescein Leakage Test Method for Identifying Ocular Corrosives and Severe Irritants 10-02-2012 TG 460 PDF
47 OECD Test Guideline 473: In Vitro Mammalian Chromosomal Aberration Test 09-26-2014 TG 473 PDF
48 OECD Test Guideline 487: In Vitro Mammalian Cell Micronucleus Test 09-28-2014 TG 487 PDF
49 OECD Test Guideline 489: In Vivo Mammalian Alkaline Comet Assay 09-26-2014 TG 489 PDF
50 OECD Test Guideline 491: Short Time Exposure In Vitro Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage 07-28-2015 TG 491 PDF
51 OECD Test Guideline 456: H295R Steroidogenesis Assay 07-28-2011 TG456 PDF

  Back to Top

File Assistance: Free downloads for viewing files.

USA.gov is the U.S. government's official web portal to all federal, state, and local government web resources and services U.S. Department of Health and Human Services
The NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.