Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.


The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Internet Explorer is no longer a supported browser.

This website may not display properly with Internet Explorer. For the best experience, please use a more recent browser such as the latest versions of Google Chrome, Microsoft Edge, and/or Mozilla Firefox. Thank you.

Your Environment. Your Health.


Export to Word (
Principal Investigator: Peters, Junenette
Institute Receiving Award Boston University Medical Campus
Location Boston, MA
Grant Number R01ES025791
Funding Organization National Institute of Environmental Health Sciences
Award Funding Period 01 Aug 2016 to 30 Jun 2021
DESCRIPTION (provided by applicant):  : Aircraft noise is a considerable source of stress among near-airport communities. Exposure has been associated with sleep disturbance, physiological responses and psychological reactions, with corresponding effects on blood pressure. However, the extent to which aircraft noise increases the risk of cardiovascular disease (CVD) has not been fully elucidated. Likewise, the role of CVD risk factors in mediating an association between noise and CVD has not been assessed. Additionally, exposure assessment that includes time-varying and spatially resolved noise exposures has not been systematically incorporated into previous epidemiological studies. This study proposes to evaluate the effects of aircraft noise exposure on CVD in the longitudinal Women's Health Initiative (WHI) study cohorts, in which over 160,000 women were recruited from 1993 to 1998 from 40 clinics in 24 states. To our knowledge, this represents the first study to apply aircraft noise exposure to a cohort study spanning a large number of airports. Specifically, this study will address previous study limitations and expand our understanding of the noise-health relationship by: (1) building historical noise models to assign exposure to residential addresses over time (1993-2012); (2) evaluating the relationship between aircraft noise exposure and CVD considering other noise sources and air pollution exposure; and (3) investigating the effect of exposure on CVD risk factors and roles of these risk factors as mediators of the noise-CVD relationship. Results from this study will allow us to estimate the proportion of CVD that could be reduced by decreasing exposure. As growth in aviation is anticipated and international, national and local interest in noise increases, the results of this timely study will inform strategies for reducing adverse health effects of aircraft noise and decisions regarding ambient noise levels that merit intervention.
Science Code(s)/Area of Science(s) Primary: 41 - Cardiovascular System
Publications See publications associated with this Grant.
Program Officer Bonnie Joubert
to Top