Project Title: | DETECTION AND MODELS OF TOXICANT EXPOSURE |
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PI: | Tukey, Robert H |
Institution: | University Of California, San Diego |
Grant Number: | P42ES010337 |
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Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
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Adaptation of the brainwriting premortem technique to inform the co-creation of COVID-19 testing str ... | Rabin, Borsika A; Cain, Kelli L; Ayers, Lawrence O; Lomeli, Angel; Escoto, Arleth; Burola, Mar ... | P42ES010337 | BMC Health Serv Res (2024 Jan 03) | 38172787 | 2024 |
From NAFLD to MASLD: implications of the new nomenclature for preclinical and clinical research. | Hsu, Cynthia L; Loomba, Rohit | P42ES010337 | Nat Metab (2024 Feb 21) | 38383845 | 2024 |
NASH is the Leading Cause of Hepatocellular Carcinoma in Liver Transplant Candidates. | Koh, Jia Hong; Ng, Cheng Han; Nah, Benjamin; Tan, Darren Jun Hao; Loomba, Rohit; Huang, Daniel ... | P42ES010337 | Clin Gastroenterol Hepatol (2024 Jan) | 37245718 | 2024 |
Role of Hepatic Stellate and Liver Sinusoidal Endothelial Cells in a Human Primary Cell Three-Dimens ... | Tan, Philip K; Ostertag, Traci; Rosenthal, Sara B; Chilin-Fuentes, Daisy; Aidnik, Haylee; Linke ... | P42ES010337 | Am J Pathol (2024 Mar) | 38158078 | 2024 |
The Origin and Fate of Liver Myofibroblasts. | Kim, Hyun Young; Sakane, Sadatsugu; Eguileor, Alvaro; Carvalho Gontijo Weber, Raquel; Lee, Wons ... | P42ES010337 | Cell Mol Gastroenterol Hepatol (2024) | 37743012 | 2024 |
A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer. | Antal, Corina E; Oh, Tae Gyu; Aigner, Stefan; Luo, En-Ching; Yee, Brian A; Campos, Tania; Tiri ... | P42ES010337 | Nat Commun (2023 Sep 06) | 37673892 | 2023 |
Candida albicans-specific Th17 cell-mediated response contributes to alcohol-associated liver diseas ... | Zeng, Suling; Rosati, Elisa; Saggau, Carina; Messner, Berith; Chu, Huikuan; Duan, Yi; Hartmann ... | P42ES010337 | Cell Host Microbe (2023 Mar 08) | 36893735 | 2023 |
Factors associated with COVID-19 vaccine uptake in a US/Mexico border community: demographics, previ ... | Lomeli, Angel; Escoto, Arleth A; Reyes, Breanna; Burola, Maria Linda M; Tinoco-Calvillo, Stephe ... | P42ES010337 | Front Public Health (2023) | 37575117 | 2023 |
Fibrosis Progression Rate in Biopsy-Proven Nonalcoholic Fatty Liver Disease Among People With Diabet ... | Huang, Daniel Q; Wilson, Laura A; Behling, Cynthia; Kleiner, David E; Kowdley, Kris V; Dasarath ... | P42ES010337 | Gastroenterology (2023 Aug) | 37127100 | 2023 |
Global epidemiology of alcohol-associated cirrhosis and HCC: trends, projections and risk factors. | Huang, Daniel Q; Mathurin, Philippe; Cortez-Pinto, Helena; Loomba, Rohit | P42ES010337 | Nat Rev Gastroenterol Hepatol (2023 Jan) | 36258033 | 2023 |
Hepatocellular Carcinoma Incidence in Alcohol-Associated Cirrhosis: Systematic Review and Meta-analy ... | Huang, Daniel Q; Tan, Darren J H; Ng, Cheng Han; Amangurbanova, Maral; Sutter, Nancy; Lin Tay, ... | P42ES010337 | Clin Gastroenterol Hepatol (2023 May) | 35940513 | 2023 |
Heterozygous mutations in SOX2 may cause idiopathic hypogonadotropic hypogonadism via dominant-negat ... | Cassin, Jessica; Stamou, Maria I; Keefe, Kimberly W; Sung, Kaitlin E; Bojo, Celine C; Tonsfeldt ... | P42ES010337 | JCI Insight (2023 Feb 08) | 36602867 | 2023 |
Isolation of primary human liver cells from normal and nonalcoholic steatohepatitis livers. | Liu, Xiao; Lam, Kevin; Zhao, Huayi; Sakane, Sadatsugu; Kim, Hyun Young; Eguileor, Alvaro; Digg ... | P42ES010337 | STAR Protoc (2023 Sep 15) | 37405925 | 2023 |
Liver stiffness thresholds to predict disease progression and clinical outcomes in bridging fibrosis ... | Loomba, Rohit; Huang, Daniel Q; Sanyal, Arun J; Anstee, Quentin Mark; Trauner, Michael; Lawitz, ... | P42ES010337 | Gut (2023 Mar) | 36750244 | 2023 |
Meta-analysis: Chemoprevention of hepatocellular carcinoma with statins, aspirin and metformin. | Zeng, Rebecca W; Yong, Jie Ning; Tan, Darren J H; Fu, Clarissa E; Lim, Wen Hui; Xiao, Jieling; ... | P42ES010337 | Aliment Pharmacol Ther (2023 Mar) | 36625733 | 2023 |
Meta-analysis: Prevalence of significant or advanced fibrosis in adults with alpha-1-antitrypsin def ... | Huang, Daniel Q; Chan, Kai En; Tan, Caitlyn; Zeng, Rebecca Wenling; Koh, Benjamin; Ong, Elden ... | P42ES010337 | Aliment Pharmacol Ther (2023 Jul) | 37089038 | 2023 |
Oral arsenic administration to humanizedUDP-glucuronosyltransferase1 neonatal mice induces UGT1A1 th ... | Yang, Xiaojing; Weber, André A; Mennillo, Elvira; Paszek, Miles; Wong, Samantha; Le, Sabrina; ... | P42ES010337, R21ES034630 | J Biol Chem (2023 Mar) | 36720308 | 2023 |
Prevalence and factors associated with liver fibrosis among first-degree relatives of Mexican Americ ... | Sharpton, Suzanne; Shan, Kuangda; Bettencourt, Ricki; Lee, Miryoung; McCormick, Joseph B; Fishe ... | P42ES010337 | Aliment Pharmacol Ther (2023 Feb) | 36628455 | 2023 |
Psoriatic disease and non-alcoholic fatty liver disease shared pathogenesis review. | Torosian, Kelly; Lal, Esha; Kavanaugh, Arthur; Loomba, Rohit; Ajmera, Veeral; Guma, Monica | P42ES010337 | Semin Arthritis Rheum (2023 Apr) | 36716599 | 2023 |
Ramipril for the Treatment of COVID-19: RAMIC, a Randomized, Double-Blind, Placebo-Controlled Clinic ... | Huang, Daniel Q; Ajmera, Veeral; Tomaszewski, Christian; LaFree, Andrew; Bettencourt, Ricki; Th ... | P42ES010337 | Adv Ther (2023 Nov) | 37615850 | 2023 |
Review article: Available modalities for screening and imaging diagnosis of hepatocellular carcinoma ... | Barnard Giustini, Abbey; Ioannou, George N; Sirlin, Claude; Loomba, Rohit | P42ES010337 | Aliment Pharmacol Ther (2023 May) | 37038283 | 2023 |
Review article: the role of HSD17B13 on global epidemiology, natural history, pathogenesis and treat ... | Amangurbanova, Maral; Huang, Daniel Q; Loomba, Rohit | P42ES010337 | Aliment Pharmacol Ther (2023 Jan) | 36349732 | 2023 |
The transcription factor VAX1 in VIP neurons of the suprachiasmatic nucleus impacts circadian rhythm ... | Van Loh, Brooke M; Yaw, Alexandra M; Breuer, Joseph A; Jackson, Brooke; Nguyen, Duong; Jang, K ... | P42ES010337 | Front Endocrinol (Lausanne) (2023) | 38205198 | 2023 |
Therapeutic blockade of ER stress and inflammation prevents NASH and progression to HCC. | Boslem, Ebru; Reibe, Saskia; Carlessi, Rodrigo; Smeuninx, Benoit; Tegegne, Surafel; Egan, Case ... | P42ES010337 | Sci Adv (2023 Sep 15) | 37703359 | 2023 |
Type 2 diabetes, hepatic decompensation, and hepatocellular carcinoma in patients with non-alcoholic ... | Huang, Daniel Q; Noureddin, Nabil; Ajmera, Veeral; Amangurbanova, Maral; Bettencourt, Ricki; Tr ... | P42ES010337 | Lancet Gastroenterol Hepatol (2023 Sep) | 37419133 | 2023 |
Using ethnographic approaches to document, evaluate, and facilitate virtual community-engaged implem ... | Rabin, Borsika A; Cain, Kelli L; Salgin, Linda; Watson Jr, Paul L; Oswald, William; Kaiser, Bo ... | P42ES010337 | BMC Public Health (2023 Feb 28) | 36855118 | 2023 |
Zinc accumulation in Atriplex lentiformis is driven by plant genes and the soil microbiome. | Kushwaha, Priyanka; Tran, Alexandria; Quintero, Diego; Song, Miranda; Yu, Qi; Yu, Ruth; Downes ... | P42ES004940, P42ES010337 | Sci Total Environ (2023 Nov 15) | 37478925 | 2023 |
Aberrant iron distribution via hepatocyte-stellate cell axis drives liver lipogenesis and fibrosis. | Gao, Hong; Jin, Zhongmou; Bandyopadhyay, Gautam; Wang, Gaowei; Zhang, Dinghong; Rocha, Karina ... | P42ES010337 | Cell Metab (2022 Aug 02) | 35921818 | 2022 |
Changing global epidemiology of liver cancer from 2010 to 2019: NASH is the fastest growing cause of ... | Huang, Daniel Q; Singal, Amit G; Kono, Yuko; Tan, Darren J H; El-Serag, Hashem B; Loomba, Rohi ... | P42ES010337 | Cell Metab (2022 Jul 05) | 35793659 | 2022 |
Circadian Rhythms in the Neuronal Network Timing the Luteinizing Hormone Surge. | Tonsfeldt, Karen J; Mellon, Pamela L; Hoffmann, Hanne M | P42ES010337 | Endocrinology (2022 Feb 01) | 34967900 | 2022 |
Co-creating a Theory of Change to advance COVID-19 testing and vaccine uptake in underserved communi ... | Stadnick, Nicole A; Cain, Kelli L; Oswald, William; Watson, Paul; Ibarra, Marina; Lagoc, Rapha ... | P42ES010337 | Health Serv Res (2022 Jun) | 35243622 | 2022 |
Combined effects of host genetics and diet on human gut microbiota and incident disease in a single ... | Qin, Youwen; Havulinna, Aki S; Liu, Yang; Jousilahti, Pekka; Ritchie, Scott C; Tokolyi, Alex; ... | P42ES010337 | Nat Genet (2022 Feb) | 35115689 | 2022 |
Comparative efficacy of an optimal exam between ultrasound versus abbreviated MRI for HCC screening ... | Huang, Daniel Q; Fowler, Kathryn J; Liau, Joy; Cunha, Guilherme M; Louie, Ashley L; An, Julie ... | P42ES010337 | Aliment Pharmacol Ther (2022 Apr) | 35229334 | 2022 |
Deletion of Six3 in post-proliferative neurons produces weakened SCN circadian output, improved meta ... | Meadows, Jason D; Breuer, Joseph A; Lavalle, Shanna N; Hirschenberger, Michael R; Patel, Meera ... | P42ES010337 | Mol Metab (2022 Mar) | 34974160 | 2022 |
Deletion of the homeodomain gene Six3 from kisspeptin neurons causes subfertility in female mice. | Lavalle, Shanna N; Chou, Teresa; Hernandez, Jacqueline; Naing, Nay Chi P; He, Michelle Y; Tonsf ... | P42ES010337 | Mol Cell Endocrinol (2022 Apr 15) | 35121076 | 2022 |
Early prediction of incident liver disease using conventional risk factors and gut-microbiome-augmen ... | Liu, Yang; Méric, Guillaume; Havulinna, Aki S; Teo, Shu Mei; Åberg, Fredrik; Ruuskanen, Matti; ... | P42ES010337 | Cell Metab (2022 May 03) | 35354069 | 2022 |
Editorial: screening for hepatocellular carcinoma in NAFLD cirrhosis-towards abbreviated MRI alterna ... | Huang, Daniel Q; Loomba, Rohit | P42ES010337 | Aliment Pharmacol Ther (2022 May) | 35429041 | 2022 |
Emerging advances in the pharmacologic treatment of nonalcoholic steatohepatitis and related cirrhos ... | Sinakos, Emmanouil; Liava, Christina; Loomba, Rohit | P42ES010337 | Ann Gastroenterol (2022) | 35599922 | 2022 |
Engaging Underserved Communities in COVID-19 Health Equity Implementation Research: An Analysis of C ... | Stadnick, Nicole A; Cain, Kelli L; Watson, Paul; Oswald, William; Ibarra, Marina; Lagoc, Rapha ... | P42ES010337 | Front Health Serv (2022) | 36258685 | 2022 |
Expert Panel Review to Compare FDA and EMA Guidance on Drug Development and Endpoints in Nonalcoholi ... | Loomba, Rohit; Ratziu, Vlad; Harrison, Stephen A; NASH Clinical Trial Design International Workin ... | P42ES010337 | Gastroenterology (2022 Mar) | 34822801 | 2022 |
Female fertility does not require Bmal1 in suprachiasmatic nucleus neurons expressing arginine vasop ... | Tonsfeldt, Karen J; Cui, Laura J; Lee, Jinkwon; Walbeek, Thijs J; Brusman, Liza E; Jin, Ye; Mi ... | P42ES010337 | Front Endocrinol (Lausanne) (2022) | 35992114 | 2022 |
FGF1 and insulin control lipolysis by convergent pathways. | Sancar, Gencer; Liu, Sihao; Gasser, Emanuel; Alvarez, Jacqueline G; Moutos, Christopher; Kim, ... | P42ES010337 | Cell Metab (2022 Jan 04) | 34986332 | 2022 |
FXR mediates ILC-intrinsic responses to intestinal inflammation. | Fu, Ting; Li, Yuwenbin; Oh, Tae Gyu; Cayabyab, Fritz; He, Nanhai; Tang, Qin; Coulter, Sally; ... | P42ES010337 | Proc Natl Acad Sci U S A (2022 Dec 20) | 36508655 | 2022 |
Gut metagenome-derived signature predicts hepatic decompensation and mortality in NAFLD-related cirr ... | Sharpton, Suzanne R; Oh, Tae Gyu; Madamba, Egbert; Wang, Chenjingyi; Yu, Ruth T; Atkins, Annet ... | P42ES010337 | Aliment Pharmacol Ther (2022 Nov) | 36164267 | 2022 |
Hepatocellular Carcinoma Risk Assessment for Patients With Advanced Fibrosis After Eradication of He ... | Tamaki, Nobuharu; Kurosaki, Masayuki; Yasui, Yutaka; Mori, Nami; Tsuji, Keiji; Hasebe, Chitomi ... | P42ES010337 | Hepatol Commun (2022 Mar) | 34676692 | 2022 |
Interorgan crosstalk in pancreatic islet function and pathology. | Evans, Ronald M; Wei, Zong | P42ES010337 | FEBS Lett (2022 Mar) | 35014695 | 2022 |
Intestinal UDP-Glucuronosyltransferase 1A1 and Protection against Irinotecan-Induced Toxicity in a N ... | Mennillo, Elvira; Yang, Xiaojing; Weber, Andre A; Maruo, Yoshihiro; Verreault, Melanie; Barbier ... | P42ES010337 | Drug Metab Dispos (2022 Jan) | 34697081 | 2022 |
Lactational delivery of Triclosan promotes non-alcoholic fatty liver disease in newborn mice. | Weber, André A; Yang, Xiaojing; Mennillo, Elvira; Ding, Jeffrey; Watrous, Jeramie D; Jain, Moh ... | P42ES010337 | Nat Commun (2022 Jul 27) | 35896521 | 2022 |
Liver Fat Assessment in Multiview Sonography Using Transfer Learning With Convolutional Neural Netwo ... | Byra, Michal; Han, Aiguo; Boehringer, Andrew S; Zhang, Yingzhen N; O'Brien Jr, William D; Erdma ... | P42ES010337 | J Ultrasound Med (2022 Jan) | 33749862 | 2022 |
Magnetic resonance elastography plus Fibrosis-4 versus FibroScan-aspartate aminotransferase in detec ... | Tamaki, Nobuharu; Imajo, Kento; Sharpton, Suzanne; Jung, Jinho; Kawamura, Nobuyoshi; Yoneda, M ... | P42ES010337 | Hepatology (2022 Mar) | 34496054 | 2022 |
Metabolic Injury of Hepatocytes Promotes Progression of NAFLD and AALD. | Carvalho-Gontijo, Raquel; Han, Cuijuan; Zhang, Lei; Zhang, Vivian; Hosseini, Mojgan; Mekeel, K ... | P42ES010337 | Semin Liver Dis (2022 Aug) | 36001995 | 2022 |
MiR-690 treatment causes decreased fibrosis and steatosis and restores specific Kupffer cell functio ... | Gao, Hong; Jin, Zhongmou; Bandyopadhyay, Gautam; Cunha E Rocha, Karina; Liu, Xiao; Zhao, Huayi ... | P42ES010337 | Cell Metab (2022 Jul 05) | 35700738 | 2022 |
Non-invasive methods for imaging hepatic steatosis and their clinical importance in NAFLD. | Tamaki, Nobuharu; Ajmera, Veeral; Loomba, Rohit | P42ES010337 | Nat Rev Endocrinol (2022 Jan) | 34815553 | 2022 |
Noninvasive Risk Stratification for Nonalcoholic Fatty Liver Disease Among Living Liver Donor Candid ... | Danis, Nilay; Weeks, Sharon R; Kim, Ahyoung; Baghdadi, Azarakhsh; Ghadimi, Maryam; Kamel, Ihab ... | P42ES010337 | Liver Transpl (2022 Apr) | 34753223 | 2022 |
Obesity alters pathology and treatment response in inflammatory disease. | Bapat, Sagar P; Whitty, Caroline; Mowery, Cody T; Liang, Yuqiong; Yoo, Arum; Jiang, Zewen; Pet ... | P42ES010337 | Nature (2022 Apr) | 35355021 | 2022 |
PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to s ... | Kim, Ju Youn; Wang, Lily Q; Sladky, Valentina C; Oh, Tae Gyu; Liu, Junlai; Trinh, Kaitlyn; Eic ... | P42ES010337 | Cell Metab (2022 Oct 04) | 36041455 | 2022 |
Plant hormone regulation of abiotic stress responses. | Waadt, Rainer; Seller, Charles A; Hsu, Po-Kai; Takahashi, Yohei; Munemasa, Shintaro; Schroeder, ... | P42ES010337 | Nat Rev Mol Cell Biol (2022 Oct) | 35513717 | 2022 |
Review article: current and emerging therapies for the management of cirrhosis and its complications ... | Tapper, Elliot B; Ufere, Nneka N; Huang, Daniel Q; Loomba, Rohit | P42ES010337 | Aliment Pharmacol Ther (2022 May) | 35235219 | 2022 |
Shared Mechanisms between Cardiovascular Disease and NAFLD. | Huang, Daniel Q; Downes, Michael; Evans, Ronald M; Witztum, Joseph L; Glass, Christopher K; Loo ... | P42ES010337 | Semin Liver Dis (2022 Nov) | 36008083 | 2022 |
Treatment Candidacy for Pharmacologic Therapies for NASH. | Rowe, Ian A; Wong, Vincent Wai-Sun; Loomba, Rohit | P42ES010337 | Clin Gastroenterol Hepatol (2022 06) | 33711479 | 2022 |
Understanding implementation research collaborations from a co-creation lens: Recommendations for a ... | Pérez Jolles, Mónica; Willging, Cathleen E; Stadnick, Nicole A; Crable, Erika L; Lengnick-Hall, ... | P42ES010337 | Front Health Serv (2022) | 36908715 | 2022 |
"Sweet death": Fructose as a metabolic toxin that targets the gut-liver axis. | Febbraio, Mark A; Karin, Michael | P42ES010337 | Cell Metab (2021 12 07) | 34619076 | 2021 |
A role for calcium-dependent protein kinases in differential CO2 - and ABA-controlled stomatal closi ... | Schulze, Sebastian; Dubeaux, Guillaume; Ceciliato, Paulo H O; Munemasa, Shintaro; Nuhkat, Maris ... | P42ES010337 | New Phytol (2021 03) | 33187027 | 2021 |
Administrative Coding in Electronic Health Care Record-Based Research of NAFLD: An Expert Panel Cons ... | Hagström, Hannes; Adams, Leon A; Allen, Alina M; Byrne, Christopher D; Chang, Yoosoo; Grønbaek, ... | P42ES010337 | Hepatology (2021 07) | 33486773 | 2021 |
Alterations in bile acid metabolizing gut microbiota and specific bile acid genes as a precision med ... | Jiao, Na; Loomba, Rohit; Yang, Zi-Huan; Wu, Dingfeng; Fang, Sa; Bettencourt, Richele; Lan, Pi ... | P42ES010337 | Physiol Genomics (2021 08 01) | 34151600 | 2021 |
An amiRNA screen uncovers redundant CBF and ERF34/35 transcription factors that differentially regul ... | Xie, Qingqing; Yu, Qi; Jobe, Timothy O; Pham, Allis; Ge, Chennan; Guo, Qianqian; Liu, Jianxiu ... | P42ES010337 | Plant Cell Environ (2021 05) | 33554343 | 2021 |
Androgen receptor positively regulates gonadotropin-releasing hormone receptor in pituitary gonadotr ... | Ryan, Genevieve E; Bohaczuk, Stephanie C; Cassin, Jessica; Witham, Emily A; Shojaei, Shadi; Ho, ... | P42ES010337 | Mol Cell Endocrinol (2021 06 15) | 33872733 | 2021 |
Associations of healthy food choices with gut microbiota profiles. | Koponen, Kari K; Salosensaari, Aaro; Ruuskanen, Matti O; Havulinna, Aki S; Männistö, Satu; Jous ... | P42ES010337 | Am J Clin Nutr (2021 Aug 02) | 34020448 | 2021 |
Bisphenol A derivatives act as novel coactivator-binding inhibitors for estrogen receptor β. | Iwamoto, Masaki; Masuya, Takahiro; Hosose, Mari; Tagawa, Koki; Ishibashi, Tomoka; Suyama, Keit ... | P42ES010337 | J Biol Chem (2021 Nov) | 34499926 | 2021 |
Bromodomain containing 9 (BRD9) regulates macrophage inflammatory responses by potentiating glucocor ... | Wang, Liu; Oh, Tae Gyu; Magida, Jason; Estepa, Gabriela; Obayomi, S M Bukola; Chong, Ling-Wa; ... | P42ES010337 | Proc Natl Acad Sci U S A (2021 08 31) | 34446564 | 2021 |
Change in Fibrosis 4 Index as Predictor of High Risk of Incident Hepatocellular Carcinoma After Erad ... | Tamaki, Nobuharu; Kurosaki, Masayuki; Yasui, Yutaka; Mori, Nami; Tsuji, Keiji; Hasebe, Chitomi ... | P42ES010337 | Clin Infect Dis (2021 11 02) | 33544129 | 2021 |
Change in MRI-PDFF and Histologic Response in Patients With Nonalcoholic Steatohepatitis: A Systemat ... | Stine, Jonathan G; Munaganuru, Nagambika; Barnard, Abbey; Wang, Jennifer L; Kaulback, Kellee; A ... | P42ES010337 | Clin Gastroenterol Hepatol (2021 11) | 32882428 | 2021 |
Clinical Care Pathway for the Risk Stratification and Management of Patients With Nonalcoholic Fatty ... | Kanwal, Fasiha; Shubrook, Jay H; Adams, Leon A; Pfotenhauer, Kim; Wai-Sun Wong, Vincent; Wright ... | P42ES010337 | Gastroenterology (2021 11) | 34602251 | 2021 |
Clinical Utility of Change in Nonalcoholic Fatty Liver Disease Activity Score and Change in Fibrosis ... | Tamaki, Nobuharu; Munaganuru, Nagambika; Jung, Jinho; Yonan, Aed Qas; Bettencourt, Richele; Ajm ... | P42ES010337 | Clin Gastroenterol Hepatol (2021 Dec) | 33157318 | 2021 |
Colon cancer checks in when bile acids check out: the bile acid-nuclear receptor axis in colon cance ... | Tang, Qin; Evans, Ronald M | P42ES010337 | Essays Biochem (2021 12 17) | 34414429 | 2021 |
Current Concepts, Opportunities, and Challenges of Gut Microbiome-Based Personalized Medicine in Non ... | Sharpton, S R; Schnabl, B; Knight, R; Loomba, R | P42ES010337 | Cell Metab (2021 Jan 05) | 33296678 | 2021 |
Distal Enhancer Potentiates Activin- and GnRH-Induced Transcription of FSHB. | Bohaczuk, Stephanie C; Cassin, Jessica; Slaiwa, Theresa I; Thackray, Varykina G; Mellon, Pamela ... | P42ES010337 | Endocrinology (2021 07 01) | 33824966 | 2021 |
Emerging Metabolic and Transcriptomic Signature of PNPLA3-Associated NASH. | Dhar, Debanjan; Loomba, Rohit | P42ES010337 | Hepatology (2021 Apr) | 33544416 | 2021 |
Emerging Role of Genomic Analysis in Clinical Evaluation of Lean Individuals With NAFLD. | Vilarinho, Sílvia; Ajmera, Veeral; Zheng, Melanie; Loomba, Rohit | P42ES010337 | Hepatology (2021 10) | 34233030 | 2021 |
FGF21 promotes thermogenic gene expression as an autocrine factor in adipocytes. | Abu-Odeh, Mohammad; Zhang, Yuan; Reilly, Shannon M; Ebadat, Nima; Keinan, Omer; Valentine, Jos ... | P42ES010337 | Cell Rep (2021 Jun 29) | 34192547 | 2021 |
From Liver Fat to Cancer: Perils of the Western Diet. | Kim, Ju Youn; He, Feng; Karin, Michael | P42ES010337 | Cancers (Basel) (2021 Mar 04) | 33806428 | 2021 |
FSHB Transcription is Regulated by a Novel 5' Distal Enhancer With a Fertility-Associated Single Nu ... | Bohaczuk, Stephanie C; Thackray, Varykina G; Shen, Jia; Skowronska-Krawczyk, Dorota; Mellon, Pa ... | P42ES010337 | Endocrinology (2021 01 01) | 33009549 | 2021 |
Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention. | Huang, Daniel Q; El-Serag, Hashem B; Loomba, Rohit | P42ES010337 | Nat Rev Gastroenterol Hepatol (2021 04) | 33349658 | 2021 |
Growth Hormone Pulses and Liver Gene Expression Are Differentially Regulated by the Circadian Clock ... | Schoeller, Erica L; Tonsfeldt, Karen J; Sinkovich, McKenna; Shi, Rujing; Mellon, Pamela L | P42ES010337 | Endocrinology (2021 04 01) | 33539533 | 2021 |
Hepatic Fibrosis Associates With Multiple Cardiometabolic Disease Risk Factors: The Framingham Heart ... | Long, Michelle T; Zhang, Xiaoyu; Xu, Hanfei; Liu, Ching-Ti; Corey, Kathleen E; Chung, Raymond ... | P42ES010337 | Hepatology (2021 Feb) | 33125745 | 2021 |
Heterogeneity of HSCs in a Mouse Model of NASH. | Rosenthal, Sara Brin; Liu, Xiao; Ganguly, Souradipta; Dhar, Debanjan; Pasillas, Martina P; Ricc ... | P42ES010337 | Hepatology (2021 Aug) | 33550587 | 2021 |
Identification and characterization of SaeIF1 from the eukaryotic translation factor SUI1 family in ... | Yu, Qi; Zhang, Zhong-Chun; Wang, Miao-Yu; Scavo, Alexander; Schroeder, Julian I; Qiu, Bao-Shen ... | P42ES010337 | Planta (2021 Jan 03) | 33389204 | 2021 |
Imaging biomarkers of NAFLD, NASH, and fibrosis. | Ajmera, Veeral; Loomba, Rohit | P42ES010337 | Mol Metab (2021 08) | 33460786 | 2021 |
Intestinal α1-2-Fucosylation Contributes to Obesity and Steatohepatitis in Mice. | Zhou, Rongrong; Llorente, Cristina; Cao, Jinling; Zaramela, Livia S; Zeng, Suling; Gao, Bei; L ... | P42ES010337 | Cell Mol Gastroenterol Hepatol (2021) | 33631374 | 2021 |
Kiss1 is differentially regulated in male and female mice by the homeodomain transcription factor VA ... | Lavalle, Shanna N; Chou, Teresa; Hernandez, Jacqueline; Naing, Nay Chi P; Tonsfeldt, Karen J; H ... | P42ES010337 | Mol Cell Endocrinol (2021 08 20) | 34098016 | 2021 |
Links between gut microbiome composition and fatty liver disease in a large population sample. | Ruuskanen, Matti O; Åberg, Fredrik; Männistö, Ville; Havulinna, Aki S; Méric, Guillaume; Liu, ... | P42ES010337 | Gut Microbes (2021 Jan-Dec) | 33651661 | 2021 |
Liver stiffness by magnetic resonance elastography is associated with increased risk of cardiovascul ... | Park, Jung Gil; Jung, Jinho; Verma, Kritin K; Kang, Min Kyu; Madamba, Egbert; Lopez, Scarlett; ... | P42ES010337 | Aliment Pharmacol Ther (2021 05) | 33764550 | 2021 |
Machine learning enables new insights into genetic contributions to liver fat accumulation. | Haas, Mary E; Pirruccello, James P; Friedman, Samuel N; Wang, Minxian; Emdin, Connor A; Ajmera, ... | P42ES010337 | Cell Genom (2021 Dec 08) | 34957434 | 2021 |
Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation ... | Xian, Hongxu; Liu, Yuan; Rundberg Nilsson, Alexandra; Gatchalian, Raphaella; Crother, Timothy R ... | P42ES010337 | Immunity (2021 Jul 13) | 34115964 | 2021 |
Molecular mechanisms of stomatal closure in response to rising vapour pressure deficit. | Jalakas, Pirko; Takahashi, Yohei; Waadt, Rainer; Schroeder, Julian I; Merilo, Ebe | P42ES010337 | New Phytol (2021 10) | 34197630 | 2021 |
MRE combined with FIB-4 (MEFIB) index in detection of candidates for pharmacological treatment of NA ... | Jung, Jinho; Loomba, Rohan R; Imajo, Kento; Madamba, Egbert; Gandhi, Sanil; Bettencourt, Ricki ... | P42ES010337 | Gut (2021 10) | 33214165 | 2021 |
MRI-Proton Density Fat Fraction Treatment Response Criteria in Nonalcoholic Steatohepatitis. | Loomba, Rohit | P42ES010337 | Hepatology (2021 Mar) | 33179266 | 2021 |
Nonalcoholic fatty liver disease as a metabolic disease in humans: A literature review. | Cariou, Bertrand; Byrne, Christopher D; Loomba, Rohit; Sanyal, Arun J | P42ES010337 | Diabetes Obes Metab (2021 05) | 33464677 | 2021 |
Nontargeted mass spectrometry of dried blood spots for interrogation of the human circulating metabo ... | Ward, Casey; Nallamshetty, Shriram; Watrous, Jeramie D; Acres, Eowyn; Long, Tao; Mathews, Ian ... | P42ES010337 | J Mass Spectrom (2021 May 27) | 34240506 | 2021 |
Optimal Threshold of Controlled Attenuation Parameter for Detection of HIV-Associated NAFLD With Mag ... | Ajmera, Veeral H; Cachay, Edward R; Ramers, Christian B; Bassirian, Shirin; Singh, Seema; Bette ... | P42ES010337 | Clin Infect Dis (2021 06 15) | 32975278 | 2021 |
Potential of therapeutic bile acids in the treatment of neonatal Hyperbilirubinemia. | van der Schoor, Lori W E; Verkade, Henkjan J; Bertolini, Anna; de Wit, Sanne; Mennillo, Elvira; ... | P42ES010337 | Sci Rep (2021 May 27) | 34045606 | 2021 |
Protein kinase sensors: an overview of new designs for visualizing kinase dynamics in single plant c ... | Zhang, Li; Takahashi, Yohei; Schroeder, Julian I | P42ES010337 | Plant Physiol (2021 Oct 05) | 35142856 | 2021 |
Publisher Correction: Immune-evasive human islet-like organoids ameliorate diabetes. | Yoshihara, Eiji; O'Connor, Carolyn; Gasser, Emanuel; Wei, Zong; Oh, Tae Gyu; Tseng, Tiffany W; ... | P42ES010337 | Nature (2021 Feb) | 33469222 | 2021 |
RAMIC: Design of a randomized, double-blind, placebo-controlled trial to evaluate the efficacy of ra ... | Ajmera, Veeral; Thompson, Wesley K; Smith, Davey M; Malhotra, Atul; Mehta, Ravindra L; Tolia, ... | P42ES010337 | Contemp Clin Trials (2021 Apr) | 33631357 | 2021 |
Randomised clinical trial: Pemafibrate, a novel selective peroxisome proliferator-activated receptor ... | Nakajima, Atsushi; Eguchi, Yuichiro; Yoneda, Masato; Imajo, Kento; Tamaki, Nobuharu; Suganami, ... | P42ES010337 | Aliment Pharmacol Ther (2021 11) | 34528723 | 2021 |
Randomised clinical trial: semaglutide versus placebo reduced liver steatosis but not liver stiffnes ... | Flint, Anne; Andersen, Grit; Hockings, Paul; Johansson, Lars; Morsing, Anni; Sundby Palle, Mad ... | P42ES010337 | Aliment Pharmacol Ther (2021 11) | 34570916 | 2021 |
Regulation of Intestinal UDP-Glucuronosyltransferase 1A1 by the Farnesoid X Receptor Agonist Obetich ... | Weber, André A; Mennillo, Elvira; Yang, Xiaojing; van der Schoor, Lori W E; Jonker, Johan W; Ch ... | P42ES010337 | Drug Metab Dispos (2021 01) | 33154041 | 2021 |
Reproductive Deficits Induced by Prenatal Antimüllerian Hormone Exposure Require Androgen Receptor i ... | Ho, Emily V; Shi, Chengxian; Cassin, Jessica; He, Michelle Y; Nguyen, Ryan D; Ryan, Genevieve ... | P42ES010337 | Endocrinology (2021 12 01) | 34529765 | 2021 |
Signaling mechanisms in abscisic acid-mediated stomatal closure. | Hsu, Po-Kai; Dubeaux, Guillaume; Takahashi, Yohei; Schroeder, Julian I | P42ES010337 | Plant J (2021 01) | 33145840 | 2021 |
Systematic review with network meta-analysis: comparative efficacy of pharmacologic therapies for fi ... | Majzoub, Abdul M; Nayfeh, Tarek; Barnard, Abbey; Munaganuru, Nagambika; Dave, Shravan; Singh, ... | P42ES010337 | Aliment Pharmacol Ther (2021 Oct) | 34435378 | 2021 |
The Commensal Microbe Veillonella as a Marker for Response to an FGF19 Analog in NASH. | Loomba, Rohit; Ling, Lei; Dinh, Duy M; DePaoli, Alex M; Lieu, Hsiao D; Harrison, Stephen A; Sa ... | P42ES010337 | Hepatology (2021 01) | 32794259 | 2021 |
The impact of genetic risk on liver fibrosis in non-alcoholic fatty liver disease as assessed by mag ... | Ajmera, Veeral; Liu, Amy; Bettencourt, Ricki; Dhar, Debanjan; Richards, Lisa; Loomba, Rohit | P42ES010337 | Aliment Pharmacol Ther (2021 07) | 33975381 | 2021 |
The Relationship Between Type 2 Diabetes, NAFLD, and Cardiovascular Risk. | Caussy, Cyrielle; Aubin, Adrien; Loomba, Rohit | P42ES010337 | Curr Diab Rep (2021 03 19) | 33742318 | 2021 |
The SLIM1 transcription factor is required for arsenic resistance in Arabidopsis thaliana. | Jobe, Timothy O; Yu, Qi; Hauser, Felix; Xie, Qingqing; Meng, Yuan; Maassen, Tim; Kopriva, Sta ... | P42ES010337 | FEBS Lett (2021 06) | 33960401 | 2021 |
The transcription factors SIX3 and VAX1 are required for suprachiasmatic nucleus circadian output an ... | Hoffmann, Hanne M; Meadows, Jason D; Breuer, Joseph A; Yaw, Alexandra M; Nguyen, Duong; Tonsfel ... | P42ES010337 | J Neurosci Res (2021 10) | 34212416 | 2021 |
Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction ... | Xu, Shihao; Chaudhary, Omkar; Rodríguez-Morales, Patricia; Sun, Xiaoli; Chen, Dan; Zappasodi, ... | P42ES010337 | Immunity (2021 Jul 13) | 34102100 | 2021 |
A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis. | Oh, Tae Gyu; Kim, Susy M; Caussy, Cyrielle; Fu, Ting; Guo, Jian; Bassirian, Shirin; Singh, Se ... | P42ES010337 | Cell Metab (2020 Nov 03) | 33147487 | 2020 |
A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis. | Oh, Tae Gyu; Kim, Susy M; Caussy, Cyrielle; Fu, Ting; Guo, Jian; Bassirian, Shirin; Singh, Se ... | P42ES010337 | Cell Metab (2020 11 03) | 32610095 | 2020 |
Advances in non-invasive assessment of hepatic fibrosis. | Loomba, Rohit; Adams, Leon A | P42ES010337 | Gut (2020 07) | 32066623 | 2020 |
Advances in non-invasive biomarkers for the diagnosis and monitoring of non-alcoholic fatty liver di ... | Long, Michelle T; Gandhi, Sanil; Loomba, Rohit | P42ES010337 | Metabolism (2020 10) | 32387227 | 2020 |
AGA Clinical Practice Update on Screening and Surveillance for Hepatocellular Carcinoma in Patients ... | Loomba, Rohit; Lim, Joseph K; Patton, Heather; El-Serag, Hashem B | P42ES010337 | Gastroenterology (2020 05) | 32006545 | 2020 |
An AMPK-caspase-6 axis controls liver damage in nonalcoholic steatohepatitis. | Zhao, Peng; Sun, Xiaoli; Chaggan, Cynthia; Liao, Zhongji; In Wong, Kai; He, Feng; Singh, Seem ... | P42ES010337 | Science (2020 02 07) | 32029622 | 2020 |
An update on the role of the microbiome in non-alcoholic fatty liver disease pathogenesis, diagnosis ... | Mouzaki, Marialena; Loomba, Rohit | P42ES010337 | Curr Treat Options Gastroenterol (2020 Jun) | 33716495 | 2020 |
Assessment of Hepatic Steatosis in Nonalcoholic Fatty Liver Disease by Using Quantitative US. | Han, Aiguo; Zhang, Yingzhen N; Boehringer, Andrew S; Montes, Vivian; Andre, Michael P; Erdman J ... | P42ES010337 | Radiology (2020 04) | 32013792 | 2020 |
Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in ... | Xu, Jun; Ma, Hsiao-Yen; Liu, Xiao; Rosenthal, Sara; Baglieri, Jacopo; McCubbin, Ryan; Sun, Me ... | P42ES010337 | JCI Insight (2020 02 13) | 32051339 | 2020 |
CBASS Immunity Uses CARF-Related Effectors to Sense 3'-5'- and 2'-5'-Linked Cyclic Oligonucleotide S ... | Lowey, Brianna; Whiteley, Aaron T; Keszei, Alexander F A; Morehouse, Benjamin R; Mathews, Ian T ... | P42ES010337 | Cell (2020 07 09) | 32544385 | 2020 |
Clinical Research in Hepatology in the COVID-19 Pandemic and Post-Pandemic Era: Challenges and the N ... | Verna, Elizabeth C; Serper, Marina; Chu, Jaime; Corey, Kathleen; Fix, Oren K; Hoyt, Karen; Pag ... | P42ES010337 | Hepatology (2020 11) | 32740969 | 2020 |
Clinical Utility of an Increase in Magnetic Resonance Elastography in Predicting Fibrosis Progressio ... | Ajmera, Veeral H; Liu, Amy; Singh, Seema; Yachoa, Georg; Ramey, Matthew; Bhargava, Meera; Zama ... | P42ES010337 | Hepatology (2020 03) | 31556124 | 2020 |
Combination therapy for non-alcoholic steatohepatitis: rationale, opportunities and challenges. | Dufour, Jean-François; Caussy, Cyrielle; Loomba, Rohit | P42ES010337 | Gut (2020 Oct) | 32381514 | 2020 |
Decreased adipose tissue oxygenation associates with insulin resistance in individuals with obesity. | Cifarelli, Vincenza; Beeman, Scott C; Smith, Gordon I; Yoshino, Jun; Morozov, Darya; Beals, Jo ... | P42ES010337 | J Clin Invest (2020 12 01) | 33164985 | 2020 |
Differential Role of Liver X Receptor (LXR) α and LXRβ in the Regulation of UDP-Glucuronosyltransfer ... | Hansmann, Eva; Mennillo, Elvira; Yoda, Emiko; Verreault, Mélanie; Barbier, Olivier; Chen, Shuj ... | P42ES010337 | Drug Metab Dispos (2020 04) | 31980500 | 2020 |
Effects of Diet versus Gastric Bypass on Metabolic Function in Diabetes. | Yoshino, Mihoko; Kayser, Brandon D; Yoshino, Jun; Stein, Richard I; Reeds, Dominic; Eagon, J C ... | P42ES010337 | N Engl J Med (2020 Aug 20) | 32813948 | 2020 |
Evidence-based clinical advice for nutrition and dietary weight loss strategies for the management o ... | Hydes, Theresa J; Ravi, Sujan; Loomba, Rohit; E Gray, Meagan | P42ES010337 | Clin Mol Hepatol (2020 10) | 32674529 | 2020 |
Fructose stimulated de novo lipogenesis is promoted by inflammation. | Todoric, Jelena; Di Caro, Giuseppe; Reibe, Saskia; Henstridge, Darren C; Green, Courtney R; Vrb ... | P42ES010337 | Nat Metab (2020 10) | 32839596 | 2020 |
Genomic and Epigenomic Landscaping Defines New Therapeutic Targets for Adenosquamous Carcinoma of th ... | Lenkiewicz, Elizabeth; Malasi, Smriti; Hogenson, Tara L; Flores, Luis F; Barham, Whitney; Phill ... | P42ES010337 | Cancer Res (2020 10 15) | 32928922 | 2020 |
Global chemical effects of the microbiome include new bile-acid conjugations. | Quinn, Robert A; Melnik, Alexey V; Vrbanac, Alison; Fu, Ting; Patras, Kathryn A; Christy, Mitc ... | P42ES010337 | Nature (2020 Mar) | 32103176 | 2020 |
GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadot ... | Nicholas, Dequina A; Knight, Vashti S; Tonsfeldt, Karen J; Terasaka, Tomohiro; Molinar-Inglis, ... | P42ES010337 | Sci Rep (2020 08 03) | 32747664 | 2020 |
Glyphosate Excretion is Associated With Steatohepatitis and Advanced Liver Fibrosis in Patients With ... | Mills, Paul J; Caussy, Cyrielle; Loomba, Rohit | P42ES010337 | Clin Gastroenterol Hepatol (2020 03) | 30954713 | 2020 |
IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcoho ... | Ma, Hsiao-Yen; Yamamoto, Gen; Xu, Jun; Liu, Xiao; Karin, Daniel; Kim, Ju Youn; Alexandrov, Lu ... | P42ES010337 | J Hepatol (2020 05) | 31899206 | 2020 |
Immune-evasive human islet-like organoids ameliorate diabetes. | Yoshihara, Eiji; O'Connor, Carolyn; Gasser, Emanuel; Wei, Zong; Oh, Tae Gyu; Tseng, Tiffany W; ... | P42ES010337 | Nature (2020 Oct) | 32814902 | 2020 |
Initiation of Parental Genome Reprogramming in Fertilized Oocyte by Splicing Kinase SRPK1-Catalyzed ... | Gou, Lan-Tao; Lim, Do-Hwan; Ma, Wubin; Aubol, Brandon E; Hao, Yajing; Wang, Xin; Zhao, Jun; L ... | P42ES010337 | Cell (2020 03 19) | 32169215 | 2020 |
Intestinal Virome Signature Associated With Severity of Nonalcoholic Fatty Liver Disease. | Lang, Sonja; Demir, Münevver; Martin, Anna; Jiang, Lu; Zhang, Xinlian; Duan, Yi; Gao, Bei; Wi ... | P42ES010337 | Gastroenterology (2020 11) | 32652145 | 2020 |
Liver Stiffness Severity is Associated With Increased Cardiovascular Risk in Patients With Type 2 Di ... | Mangla, Neeraj; Ajmera, Veeral H; Caussy, Cyrielle; Sirlin, Claude; Brouha, Sharon; Bajwa-Dulai ... | P42ES010337 | Clin Gastroenterol Hepatol (2020 03) | 31100460 | 2020 |
MAP3Kinase-dependent SnRK2-kinase activation is required for abscisic acid signal transduction and r ... | Takahashi, Yohei; Zhang, Jingbo; Hsu, Po-Kai; Ceciliato, Paulo H O; Zhang, Li; Dubeaux, Guilla ... | P42ES010337 | Nat Commun (2020 01 02) | 31896774 | 2020 |
Mechanisms of liver fibrosis and its role in liver cancer. | Dhar, Debanjan; Baglieri, Jacopo; Kisseleva, Tatiana; Brenner, David A | P42ES010337 | Exp Biol Med (Maywood) (2020 Jan) | 31924111 | 2020 |
Monitoring and mitigation of toxic heavy metals and arsenic accumulation in food crops: A case study ... | Cooper, Andrew M; Felix, Didra; Alcantara, Fatima; Zaslavsky, Ilya; Work, Amy; Watson, Paul L; ... | P42ES010337 | Plant Direct (2020 Jan) | 31956855 | 2020 |
NCoR1 Protects Mice From Dextran Sodium Sulfate-Induced Colitis by Guarding Colonic Crypt Cells From ... | Mennillo, Elvira; Yang, Xiaojing; Paszek, Miles; Auwerx, Johan; Benner, Christopher; Chen, Shu ... | P42ES010337 | Cell Mol Gastroenterol Hepatol (2020) | 32044398 | 2020 |
Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis. | Sun, Xiaoli; Seidman, Jason S; Zhao, Peng; Troutman, Ty D; Spann, Nathanael J; Que, Xuchu; Zho ... | P42ES010337 | Cell Metab (2020 01 07) | 31761566 | 2020 |
NF-κB-p62-NRF2 survival signaling is associated with high ROR1 expression in chronic lymphocytic leu ... | Sanchez-Lopez, Elsa; Ghia, Emanuela M; Antonucci, Laura; Sharma, Natasha; Rassenti, Laura Z; Xu ... | P42ES010337 | Cell Death Differ (2020 07) | 31992855 | 2020 |
Noninvasive Diagnosis of Nonalcoholic Fatty Liver Disease and Quantification of Liver Fat with Radio ... | Han, Aiguo; Byra, Michal; Heba, Elhamy; Andre, Michael P; Erdman Jr, John W; Loomba, Rohit; Si ... | P42ES010337 | Radiology (2020 05) | 32096706 | 2020 |
NRF2 activates growth factor genes and downstream AKT signaling to induce mouse and human hepatomega ... | He, Feng; Antonucci, Laura; Yamachika, Shinichiro; Zhang, Zechuan; Taniguchi, Koji; Umemura, A ... | P42ES010337 | J Hepatol (2020 06) | 32105670 | 2020 |
NRF2 as a regulator of cell metabolism and inflammation in cancer. | He, Feng; Antonucci, Laura; Karin, Michael | P42ES010337 | Carcinogenesis (2020 06 17) | 32347301 | 2020 |
NRF2-Independent Regulation of Intestinal Constitutive Androstane Receptor by the Pro-Oxidants Cadmi ... | Paszek, Miles; Tukey, Robert H | P42ES010337 | Drug Metab Dispos (2020 01) | 31704714 | 2020 |
PNPLA3 Genotype and Risk of Liver and All-Cause Mortality. | Stender, Stefan; Loomba, Rohit | P42ES010337 | Hepatology (2020 03) | 31954067 | 2020 |
Prospective, Same-Day, Direct Comparison of Controlled Attenuation Parameter With the M vs the XL Pr ... | Caussy, Cyrielle; Brissot, Justine; Singh, Seema; Bassirian, Shirin; Hernandez, Carolyn; Betten ... | P42ES010337 | Clin Gastroenterol Hepatol (2020 Jul) | 31843596 | 2020 |
Stem cell regionalization during olfactory bulb neurogenesis depends on regulatory interactions betw ... | Coré, Nathalie; Erni, Andrea; Hoffmann, Hanne M; Mellon, Pamela L; Saurin, Andrew J; Beclin, C ... | P42ES010337 | Elife (2020 Aug 07) | 32762844 | 2020 |
Targeting the renin-angiotensin signaling pathway in COVID-19: Unanswered questions, opportunities, ... | Sriram, Krishna; Loomba, Rohit; Insel, Paul A | P42ES010337 | Proc Natl Acad Sci U S A (2020 11 24) | 33203679 | 2020 |
The Homeodomain Transcription Factors Vax1 and Six6 Are Required for SCN Development and Function. | Pandolfi, Erica C; Breuer, Joseph A; Nguyen Huu, Viet Anh; Talluri, Tulasi; Nguyen, Duong; Lee, ... | P42ES010337 | Mol Neurobiol (2020 Feb) | 31705443 | 2020 |
The Role of Noninvasive Tests for Differentiating NASH From NAFL and Diagnosing Advanced Fibrosis Am ... | Balakrishnan, Maya; Loomba, Rohit | P42ES010337 | J Clin Gastroenterol (2020 02) | 31789757 | 2020 |
Triclosan leads to dysregulation of the metabolic regulator FGF21 exacerbating high fat diet-induced ... | Yueh, Mei-Fei; He, Feng; Chen, Chen; Vu, Catherine; Tripathi, Anupriya; Knight, Rob; Karin, M ... | P42ES010337 | Proc Natl Acad Sci U S A (2020 12 08) | 33229553 | 2020 |
Triptolide targets super-enhancer networks in pancreatic cancer cells and cancer-associated fibrobla ... | Noel, Pawan; Hussein, Shaimaa; Ng, Serina; Antal, Corina E; Lin, Wei; Rodela, Emily; Delgado, ... | P42ES010337 | Oncogenesis (2020 Nov 09) | 33168807 | 2020 |
A gut microbiome signature for cirrhosis due to nonalcoholic fatty liver disease. | Caussy, Cyrielle; Tripathi, Anupriya; Humphrey, Greg; Bassirian, Shirin; Singh, Seema; Faulkner ... | P42ES010337 | Nat Commun (2019 03 29) | 30926798 | 2019 |
A seed resource for screening functionally redundant genes and isolation of new mutants impaired in ... | Hauser, Felix; Ceciliato, Paulo H O; Lin, Yi-Chen; Guo, DanDan; Gregerson, J D; Abbasi, Nazia; ... | P42ES010337 | J Exp Bot (2019 01 07) | 30346611 | 2019 |
Chemical genetic identification of a lectin receptor kinase that transduces immune responses and int ... | Park, Jiyoung; Kim, Tae-Houn; Takahashi, Yohei; Schwab, Rebecca; Dressano, Keini; Stephan, Aar ... | P42ES010337 | Plant J (2019 May) | 30659683 | 2019 |
Choline Uptake and Metabolism Modulate Macrophage IL-1β and IL-18 Production. | Sanchez-Lopez, Elsa; Zhong, Zhenyu; Stubelius, Alexandra; Sweeney, Shannon R; Booshehri, Laela ... | P42ES010337 | Cell Metab (2019 06 04) | 30982734 | 2019 |
Collagen Formation Assessed by N-Terminal Propeptide of Type 3 Procollagen Is a Heritable Trait and ... | Caussy, Cyrielle; Bhargava, Meera; Villesen, Ida F; Gudmann, Natasja S; Leeming, Diana J; Karsd ... | P42ES010337 | Hepatology (2019 07) | 30859582 | 2019 |
Cytogenetic, Genomic, and Functional Characterization of Pituitary Gonadotrope Cell Lines. | Ruf-Zamojski, Frederique; Ge, Yongchao; Pincas, Hanna; Shan, Jidong; Song, Yinghui; Hines, Nik ... | P42ES010337 | J Endocr Soc (2019 May 01) | 31020055 | 2019 |
Deletion of the Homeodomain Protein Six6 From GnRH Neurons Decreases GnRH Gene Expression, Resulting ... | Pandolfi, Erica C; Tonsfeldt, Karen J; Hoffmann, Hanne M; Mellon, Pamela L | P42ES010337 | Endocrinology (2019 09 01) | 31211355 | 2019 |
Differential CRE Expression in Lhrh-cre and GnRH-cre Alleles and the Impact on Fertility in Otx2-Flo ... | Hoffmann, Hanne M; Larder, Rachel; Lee, Jessica S; Hu, Rachael J; Trang, Crystal; Devries, Bro ... | P42ES010337 | Neuroendocrinology (2019) | 30739114 | 2019 |
FXR Regulates Intestinal Cancer Stem Cell Proliferation. | Fu, Ting; Coulter, Sally; Yoshihara, Eiji; Oh, Tae Gyu; Fang, Sungsoon; Cayabyab, Fritz; Zhu, ... | P42ES010337 | Cell (2019 02 21) | 30794774 | 2019 |
Genetic strategies for improving crop yields. | Bailey-Serres, Julia; Parker, Jane E; Ainsworth, Elizabeth A; Oldroyd, Giles E D; Schroeder, Ju ... | P42ES010337 | Nature (2019 11) | 31695205 | 2019 |
Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human ... | Loomba, Rohit; Seguritan, Victor; Li, Weizhong; Long, Tao; Klitgord, Niels; Bhatt, Archana; Du ... | P42ES010337 | Cell Metab (2019 Sep 03) | 31484056 | 2019 |
Haploinsufficiency of Homeodomain Proteins Six3, Vax1, and Otx2 Causes Subfertility in Mice via Dist ... | Hoffmann, Hanne M; Pandolfi, Erica C; Larder, Rachel; Mellon, Pamela L | P42ES010337 | Neuroendocrinology (2019) | 30261489 | 2019 |
Insights into the evolving role of the gut microbiome in nonalcoholic fatty liver disease: rationale ... | Mouzaki, Marialena; Loomba, Rohit | P42ES010337 | Therap Adv Gastroenterol (2019) | 31258623 | 2019 |
Intact leaf gas exchange provides a robust method for measuring the kinetics of stomatal conductance ... | Ceciliato, Paulo H O; Zhang, Jingbo; Liu, Qing; Shen, Xin; Hu, Honghong; Liu, Chen; Schäffner, ... | P42ES010337 | Plant Methods (2019) | 31019545 | 2019 |
NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice. | Liang, Shuang; Ma, Hsiao-Yen; Zhong, Zhenyu; Dhar, Debanjan; Liu, Xiao; Xu, Jun; Koyama, Yuki ... | P42ES010337 | Gastroenterology (2019 03) | 30445007 | 2019 |
Noninvasive Assessment of Liver Disease in Patients With Nonalcoholic Fatty Liver Disease. | Castera, Laurent; Friedrich-Rust, Mireen; Loomba, Rohit | P42ES010337 | Gastroenterology (2019 04) | 30660725 | 2019 |
Preclinical Models for Studying NASH-Driven HCC: How Useful Are They? | Febbraio, Mark A; Reibe, Saskia; Shalapour, Shabnam; Ooi, Geraldine J; Watt, Matthew J; Karin, ... | P42ES010337 | Cell Metab (2019 01 08) | 30449681 | 2019 |
RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype. | Cai, Demin; Wang, Junjian; Gao, Bei; Li, Jin; Wu, Feng; Zou, June X; Xu, Jianzhen; Jiang, Yu ... | P42ES010337 | Nat Commun (2019 10 11) | 31604910 | 2019 |
Standardising the interpretation of liver biopsies in non-alcoholic fatty liver disease clinical tri ... | Pai, Rish K; Kleiner, David E; Hart, John; Adeyi, Oyedele A; Clouston, Andrew D; Behling, Cynt ... | P42ES010337 | Aliment Pharmacol Ther (2019 11) | 31583739 | 2019 |
The 20% Rule of NASH Progression: The Natural History of Advanced Fibrosis and Cirrhosis Caused by N ... | Loomba, Rohit; Adams, Leon A | P42ES010337 | Hepatology (2019 Dec) | 31520407 | 2019 |
The Contribution of the Circadian Gene Bmal1 to Female Fertility and the Generation of the Preovulat ... | Tonsfeldt, Karen J; Schoeller, Erica L; Brusman, Liza E; Cui, Laura J; Lee, Jinkwon; Mellon, P ... | P42ES010337 | J Endocr Soc (2019 Apr 01) | 30906911 | 2019 |
The nuclear receptor REV-ERBα modulates Th17 cell-mediated autoimmune disease. | Chang, Christina; Loo, Chin-San; Zhao, Xuan; Solt, Laura A; Liang, Yuqiong; Bapat, Sagar P; Ch ... | P42ES010337 | Proc Natl Acad Sci U S A (2019 09 10) | 31455731 | 2019 |
The Role of Fibrosis and Liver-Associated Fibroblasts in the Pathogenesis of Hepatocellular Carcinom ... | Baglieri, Jacopo; Brenner, David A; Kisseleva, Tatiana | P42ES010337 | Int J Mol Sci (2019 Apr 07) | 30959975 | 2019 |
YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity. | Wang, Lirui; Mazagova, Magdalena; Pan, Chuyue; Yang, Song; Brandl, Katharina; Liu, Jun; Reilly ... | P42ES010337 | Proc Natl Acad Sci U S A (2019 Jul 23) | 31289229 | 2019 |
A transportome-scale amiRNA-based screen identifies redundant roles of Arabidopsis ABCB6 and ABCB20 ... | Zhang, Yuqin; Nasser, Victoria; Pisanty, Odelia; Omary, Moutasem; Wulff, Nikolai; Di Donato, M ... | P42ES010337 | Nat Commun (2018 10 11) | 30310073 | 2018 |
Abscisic acid-independent stomatal CO2 signal transduction pathway and convergence of CO2 and ABA si ... | Hsu, Po-Kai; Takahashi, Yohei; Munemasa, Shintaro; Merilo, Ebe; Laanemets, Kristiina; Waadt, R ... | P42ES010337 | Proc Natl Acad Sci U S A (2018 Oct 16) | 30282744 | 2018 |
Abscisic acid-induced degradation of Arabidopsis guanine nucleotide exchange factor requires calcium ... | Li, Zixing; Takahashi, Yohei; Scavo, Alexander; Brandt, Benjamin; Nguyen, Desiree; Rieu, Phili ... | P42ES010337 | Proc Natl Acad Sci U S A (2018 May 08) | 29686103 | 2018 |
Antiandrogen Treatment Ameliorates Reproductive and Metabolic Phenotypes in the Letrozole-Induced Mo ... | Ryan, Genevieve E; Malik, Shaddy; Mellon, Pamela L | P42ES010337 | Endocrinology (2018 04 01) | 29471436 | 2018 |
Author Correction: Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity. | Shalapour, Shabnam; Lin, Xue-Jia; Bastian, Ingmar N; Brain, John; Burt, Alastair D; Aksenov, A ... | P42ES010337 | Nature (2018 09) | 29973714 | 2018 |
Chemokines and Chemokine Receptors in the Development of NAFLD. | Roh, Yoon-Seok; Seki, Ekihiro | P42ES010337 | Adv Exp Med Biol (2018) | 29956205 | 2018 |
Cryo-EM Elucidation of the Structure of Bacteriophage P22 Virions after Genome Release. | McNulty, Reginald; Cardone, Giovanni; Gilcrease, Eddie B; Baker, Timothy S; Casjens, Sherwood R ... | P42ES010337 | Biophys J (2018 03 27) | 29590587 | 2018 |
ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P. | Kim, Ju Youn; Garcia-Carbonell, Ricard; Yamachika, Shinichiro; Zhao, Peng; Dhar, Debanjan; Loom ... | P42ES010337 | Cell (2018 09 20) | 30220454 | 2018 |
ERRγ Preserves Brown Fat Innate Thermogenic Activity. | Ahmadian, Maryam; Liu, Sihao; Reilly, Shannon M; Hah, Nasun; Fan, Weiwei; Yoshihara, Eiji; Jha ... | P42ES010337 | Cell Rep (2018 03 13) | 29539415 | 2018 |
ERRγ Promotes Angiogenesis, Mitochondrial Biogenesis, and Oxidative Remodeling in PGC1α/β-Deficient ... | Fan, Weiwei; He, Nanhai; Lin, Chun Shi; Wei, Zong; Hah, Nasun; Waizenegger, Wanda; He, Ming-X ... | P42ES010337 | Cell Rep (2018 03 06) | 29514081 | 2018 |
Geographic Variability in Liver Disease-Related Mortality Rates in the United States. | Desai, Archita P; Mohan, Prashanthinie; Roubal, Anne M; Bettencourt, Ricki; Loomba, Rohit | P42ES010337 | Am J Med (2018 Jul) | 29496501 | 2018 |
Haploinsufficiency of SIX3 Abolishes Male Reproductive Behavior Through Disrupted Olfactory Developm ... | Pandolfi, Erica C; Hoffmann, Hanne M; Schoeller, Erica L; Gorman, Michael R; Mellon, Pamela L | P42ES010337 | Mol Neurobiol (2018 Nov) | 29589282 | 2018 |
Humanized UGT1 Mice, Regulation of UGT1A1, and the Role of the Intestinal Tract in Neonatal Hyperbil ... | Chen, Shujuan; Tukey, Robert H | P42ES010337 | Drug Metab Dispos (2018 11) | 30093417 | 2018 |
IKKα inactivation promotes Kras-initiated lung adenocarcinoma development through disrupting major r ... | Song, Na-Young; Zhu, Feng; Wang, Zining; Willette-Brown, Jami; Xi, Sichuan; Sun, Zhonghe; Su, ... | P42ES010337 | Proc Natl Acad Sci U S A (2018 01 23) | 29311298 | 2018 |
Increased severity of liver fat content and liver fibrosis in non-alcoholic fatty liver disease corr ... | Brouha, Sharon S; Nguyen, Phirum; Bettencourt, Ricki; Sirlin, Claude B; Loomba, Rohit | P42ES010337 | Eur Radiol (2018 Apr) | 29058029 | 2018 |
Integrative genomic analysis of mouse and human hepatocellular carcinoma. | Dow, Michelle; Pyke, Rachel M; Tsui, Brian Y; Alexandrov, Ludmil B; Nakagawa, Hayato; Taniguchi ... | P42ES010337 | Proc Natl Acad Sci U S A (2018 Oct 16) | 30287485 | 2018 |
Link between gut-microbiome derived metabolite and shared gene-effects with hepatic steatosis and fi ... | Caussy, Cyrielle; Hsu, Cynthia; Lo, Min-Tzu; Liu, Amy; Bettencourt, Ricki; Ajmera, Veeral H; B ... | P42ES010337 | Hepatology (2018 09) | 29572891 | 2018 |
Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling. | Dhar, Debanjan; Antonucci, Laura; Nakagawa, Hayato; Kim, Ju Youn; Glitzner, Elisabeth; Caruso, ... | P42ES010337 | Cancer Cell (2018 06 11) | 29894692 | 2018 |
Magnetic Resonance Imaging Proton Density Fat Fraction Associates With Progression of Fibrosis in Pa ... | Ajmera, Veeral; Park, Charlie C; Caussy, Cyrielle; Singh, Seema; Hernandez, Carolyn; Bettencour ... | P42ES010337 | Gastroenterology (2018 08) | 29660324 | 2018 |
Mitogen-activated protein kinases MPK4 and MPK12 are key components mediating CO2 -induced stomatal ... | Tõldsepp, Kadri; Zhang, Jingbo; Takahashi, Yohei; Sindarovska, Yana; Hõrak, Hanna; Ceciliato, ... | P42ES010337 | Plant J (2018 12) | 30203878 | 2018 |
Modulation of the intestinal bile acid/farnesoid X receptor/fibroblast growth factor 15 axis improve ... | Hartmann, Phillipp; Hochrath, Katrin; Horvath, Angela; Chen, Peng; Seebauer, Caroline T; Lloren ... | P42ES010337 | Hepatology (2018 06) | 29159825 | 2018 |
New insights into the pathogenesis and treatment of non-viral hepatocellular carcinoma: a balancing ... | Karin, Michael | P42ES010337 | Precis Clin Med (2018 Jun) | 30687560 | 2018 |
New mitochondrial DNA synthesis enables NLRP3 inflammasome activation. | Zhong, Zhenyu; Liang, Shuang; Sanchez-Lopez, Elsa; He, Feng; Shalapour, Shabnam; Lin, Xue-Jia; ... | P42ES010337 | Nature (2018 08) | 30046112 | 2018 |
Nonalcoholic fatty liver disease, metabolic syndrome, and the fight that will define clinical practi ... | Tapper, Elliot B; Loomba, Rohit | P42ES010337 | Hepatology (2018 May) | 29222913 | 2018 |
Noninvasive imaging biomarker assessment of liver fibrosis by elastography in NAFLD. | Tapper, Elliot B; Loomba, Rohit | P42ES010337 | Nat Rev Gastroenterol Hepatol (2018 05) | 29463906 | 2018 |
Of Mice and Men and Nonalcoholic Steatohepatitis. | Brenner, David A | P42ES010337 | Hepatology (2018 12) | 30033687 | 2018 |
Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. | Que, Xuchu; Hung, Ming-Yow; Yeang, Calvin; Gonen, Ayelet; Prohaska, Thomas A; Sun, Xiaoli; Die ... | P42ES010337 | Nature (2018 Jun) | 29875409 | 2018 |
Publisher Correction: The gut-liver axis and the intersection with the microbiome. | Tripathi, Anupriya; Debelius, Justine; Brenner, David A; Karin, Michael; Loomba, Rohit; Schnabl ... | P42ES010337 | Nat Rev Gastroenterol Hepatol (2018 12) | 29785003 | 2018 |
Species differences in drug glucuronidation: Humanized UDP-glucuronosyltransferase 1 mice and their ... | Fujiwara, Ryoichi; Yoda, Emiko; Tukey, Robert H | P42ES010337 | Drug Metab Pharmacokinet (2018 Feb) | 29079228 | 2018 |
Tdp1 processes chromate-induced single-strand DNA breaks that collapse replication forks. | Ganguly, Abantika; Guo, Lan; Sun, Lingling; Suo, Fang; Du, Li-Lin; Russell, Paul | P42ES010337 | PLoS Genet (2018 08) | 30148840 | 2018 |
The contribution of toll-like receptor signaling to the development of liver fibrosis and cancer in ... | Song, Isabelle Jingyi; Yang, Yoon Mee; Inokuchi-Shimizu, Sayaka; Roh, Yoon Seok; Yang, Ling; Se ... | P42ES010337 | Int J Cancer (2018 Jan 01) | 28875549 | 2018 |
The gut-liver axis and the intersection with the microbiome. | Tripathi, Anupriya; Debelius, Justine; Brenner, David A; Karin, Michael; Loomba, Rohit; Schnabl ... | P42ES010337 | Nat Rev Gastroenterol Hepatol (2018 07) | 29748586 | 2018 |
Transcriptional interaction between cFOS and the homeodomain-binding transcription factor VAX1 on th ... | Hoffmann, Hanne M; Gong, Ping; Tamrazian, Anika; Mellon, Pamela L | P42ES010337 | Mol Cell Endocrinol (2018 Feb 05) | 28890143 | 2018 |
Vitamin D Switches BAF Complexes to Protect β Cells. | Wei, Zong; Yoshihara, Eiji; He, Nanhai; Hah, Nasun; Fan, Weiwei; Pinto, Antonio F M; Huddy, T ... | P42ES010337 | Cell (2018 May 17) | 29754817 | 2018 |
What Is the Next Frontier in Plant Engineering? | P42ES010337 | Cell (2018 Jul 26) | 30053421 | 2018 | |
A Highly Sensitive Enzymatic Catalysis System for Trace Detection of Arsenic in Water. | Liu, Yuanli; Yu, Chuanbai; Cao, Zhixin; Shvarts, Daniel; Trogler, William C | P42ES010337 | Chemistry (2017 Aug 01) | 28631380 | 2017 |
Assessment of treatment response in non-alcoholic steatohepatitis using advanced magnetic resonance ... | Lin, S C; Heba, E; Bettencourt, R; Lin, G Y; Valasek, M A; Lunde, O; Hamilton, G; Sirlin, C ... | P42ES010337 | Aliment Pharmacol Ther (2017 Mar) | 28116801 | 2017 |
Chromatin status and transcription factor binding to gonadotropin promoters in gonadotrope cell line ... | Xie, Huimin; Hoffmann, Hanne M; Iyer, Anita K; Brayman, Melissa J; Ngo, Cindy; Sunshine, Mary ... | P42ES010337 | Reprod Biol Endocrinol (2017 Oct 24) | 29065928 | 2017 |
Circadian clock cryptochrome proteins regulate autoimmunity. | Cao, Qi; Zhao, Xuan; Bai, Jingwen; Gery, Sigal; Sun, Haibo; Lin, De-Chen; Chen, Qi; Chen, Zh ... | P42ES010337 | Proc Natl Acad Sci U S A (2017 Nov 21) | 29109286 | 2017 |
Crypt Organoid Culture as an in Vitro Model in Drug Metabolism and Cytotoxicity Studies. | Lu, Wenqi; Rettenmeier, Eva; Paszek, Miles; Yueh, Mei-Fei; Tukey, Robert H; Trottier, Jocelyn; ... | P42ES010337 | Drug Metab Dispos (2017 Jul) | 28468837 | 2017 |
Developmental, Genetic, Dietary, and Xenobiotic Influences on Neonatal Hyperbilirubinemia. | Yueh, Mei-Fei; Chen, Shujuan; Nguyen, Nghia; Tukey, Robert H | P42ES010337 | Mol Pharmacol (2017 May) | 28283555 | 2017 |
Erratum to: Stress and the nonsense-mediated RNA decay pathway. | Goetz, Alexandra E; Wilkinson, Miles | P42ES010337 | Cell Mol Life Sci (2017 11) | 28905073 | 2017 |
Erratum: Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity. | Shalapour, Shabnam; Lin, Xue-Jia; Bastian, Ingmar N; Brain, John; Burt, Alastair D; Aksenov, A ... | P42ES010337 | Nature (2017 Dec 21) | 29168501 | 2017 |
Exercise Mimetics: Impact on Health and Performance. | Fan, Weiwei; Evans, Ronald M | P42ES010337 | Cell Metab (2017 Feb 07) | 27889389 | 2017 |
Farnesoid X Receptor an Emerging Target to Combat Obesity. | De Magalhaes Filho, C Daniel; Downes, Michael; Evans, Ronald M | P42ES010337 | Dig Dis (2017) | 28249279 | 2017 |
FGF1 - a new weapon to control type 2 diabetes mellitus. | Gasser, Emanuel; Moutos, Christopher P; Downes, Michael; Evans, Ronald M | P42ES010337 | Nat Rev Endocrinol (2017 Oct) | 28664920 | 2017 |
Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis. | Chung, Hyo Kyun; Ryu, Dongryeol; Kim, Koon Soon; Chang, Joon Young; Kim, Yong Kyung; Yi, Hyon- ... | P42ES010337 | J Cell Biol (2017 Jan 02) | 27986797 | 2017 |
Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human ... | Loomba, Rohit; Seguritan, Victor; Li, Weizhong; Long, Tao; Klitgord, Niels; Bhatt, Archana; Du ... | P42ES010337 | Cell Metab (2017 May 02) | 28467925 | 2017 |
Identification of Novel Fibrosis Modifiers by In Vivo siRNA Silencing. | Vollmann, Elisabeth H; Cao, Lizhi; Amatucci, Aldo; Reynolds, Taylor; Hamann, Stefan; Dalkilic-L ... | P42ES010337 | Mol Ther Nucleic Acids (2017 Jun 16) | 28624207 | 2017 |
Increased Risk of Death, in the Hospital and Outside the Intensive Care Unit, for Patients With Cirr ... | Reinders, Megan E; Wardi, Gabriel; Bettencourt, Ricki; Bouland, Daniel; Bazick, Jessica; Mendle ... | P42ES010337 | Clin Gastroenterol Hepatol (2017 Nov) | 28602970 | 2017 |
Increased risk of mortality by fibrosis stage in nonalcoholic fatty liver disease: Systematic review ... | Dulai, Parambir S; Singh, Siddharth; Patel, Janki; Soni, Meera; Prokop, Larry J; Younossi, Zob ... | P42ES010337 | Hepatology (2017 May) | 28130788 | 2017 |
Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity. | Shalapour, Shabnam; Lin, Xue-Jia; Bastian, Ingmar N; Brain, John; Burt, Alastair D; Aksenov, A ... | P42ES010337 | Nature (2017 11 16) | 29144460 | 2017 |
Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia. | Chen, Shujuan; Lu, Wenqi; Yueh, Mei-Fei; Rettenmeier, Eva; Liu, Miao; Paszek, Miles; Auwerx, ... | P42ES010337 | Proc Natl Acad Sci U S A (2017 Feb 21) | 28167773 | 2017 |
Intestinal PPARδ protects against diet-induced obesity, insulin resistance and dyslipidemia. | Doktorova, Marcela; Zwarts, Irene; Zutphen, Tim van; Dijk, Theo H van; Bloks, Vincent W; Harkem ... | P42ES010337 | Sci Rep (2017 Apr 12) | 28404991 | 2017 |
Isothiocyanates induce UGT1A1 in humanized UGT1 mice in a CAR dependent fashion that is highly depen ... | Yoda, Emiko; Paszek, Miles; Konopnicki, Camille; Fujiwara, Ryoichi; Chen, Shujuan; Tukey, Robe ... | P42ES010337 | Sci Rep (2017 04 19) | 28422158 | 2017 |
Liver inflammation and fibrosis. | Koyama, Yukinori; Brenner, David A | P42ES010337 | J Clin Invest (2017 Jan 03) | 28045404 | 2017 |
Magnetic Resonance Elastography vs Transient Elastography in Detection of Fibrosis and Noninvasive M ... | Park, Charlie C; Nguyen, Phirum; Hernandez, Carolyn; Bettencourt, Ricki; Ramirez, Kimberly; For ... | P42ES010337 | Gastroenterology (2017 Feb) | 27911262 | 2017 |
Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis. | Koyama, Yukinori; Wang, Ping; Liang, Shuang; Iwaisako, Keiko; Liu, Xiao; Xu, Jun; Zhang, Ming ... | P42ES010337 | J Clin Invest (2017 Apr 03) | 28287406 | 2017 |
Metabolic control of regulatory T cell (Treg) survival and function by Lkb1. | He, Nanhai; Fan, Weiwei; Henriquez, Brian; Yu, Ruth T; Atkins, Annette R; Liddle, Christopher; ... | P42ES010337 | Proc Natl Acad Sci U S A (2017 11 21) | 29109251 | 2017 |
Mice with hyperbilirubinemia due to Gilbert's syndrome polymorphism are resistant to hepatic steatos ... | Hinds Jr, Terry D; Hosick, Peter A; Chen, Shujuan; Tukey, Robert H; Hankins, Michael W; Nestor- ... | P42ES010337 | Am J Physiol Endocrinol Metab (2017 04 01) | 28096081 | 2017 |
NCoR1 restrains thymic negative selection by repressing Bim expression to spare thymocytes undergoin ... | Wang, Jianrong; He, Nanhai; Zhang, Na; Quan, Dexian; Zhang, Shuo; Zhang, Caroline; Yu, Ruth T ... | P42ES010337 | Nat Commun (2017 Oct 16) | 29038463 | 2017 |
Nonalcoholic fatty liver disease with cirrhosis increases familial risk for advanced fibrosis. | Caussy, Cyrielle; Soni, Meera; Cui, Jeffrey; Bettencourt, Ricki; Schork, Nicholas; Chen, Chi-H ... | P42ES010337 | J Clin Invest (2017 Jun 30) | 28628033 | 2017 |
PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality contro ... | Dickey, Audrey S; Sanchez, Dafne N; Arreola, Martin; Sampat, Kunal R; Fan, Weiwei; Arbez, Nico ... | P42ES010337 | Sci Transl Med (2017 Dec 06) | 29212711 | 2017 |
PPARδ Promotes Running Endurance by Preserving Glucose. | Fan, Weiwei; Waizenegger, Wanda; Lin, Chun Shi; Sorrentino, Vincenzo; He, Ming-Xiao; Wall, Chr ... | P42ES010337 | Cell Metab (2017 May 02) | 28467934 | 2017 |
Prediction of drug-induced liver injury using keratinocytes. | Hirashima, Rika; Itoh, Tomoo; Tukey, Robert H; Fujiwara, Ryoichi | P42ES010337 | J Appl Toxicol (2017 Jul) | 28138970 | 2017 |
Seeing is believing. | Azoulay-Shemer, Tamar; Hsu, Po-Kai; Schroeder, Julian I | P42ES010337 | Nat Plants (2017 Oct) | 28970562 | 2017 |
Severe Neonatal Hyperbilirubinemia in Crigler-Najjar Syndrome Model Mice Can Be Reversed With Zinc P ... | Fujiwara, Ryoichi; Mitsugi, Ryo; Uemura, Asuka; Itoh, Tomoo; Tukey, Robert H | P42ES010337 | Hepatol Commun (2017 Oct) | 29399656 | 2017 |
Statin Use and Risk of Cirrhosis and Related Complications in Patients With Chronic Liver Diseases: ... | Kim, Rebecca G; Loomba, Rohit; Prokop, Larry J; Singh, Siddharth | P42ES010337 | Clin Gastroenterol Hepatol (2017 Oct) | 28479502 | 2017 |
Stress and the nonsense-mediated RNA decay pathway. | Goetz, Alexandra E; Wilkinson, Miles | P42ES010337 | Cell Mol Life Sci (2017 10) | 28503708 | 2017 |
Stromal cues regulate the pancreatic cancer epigenome and metabolome. | Sherman, Mara H; Yu, Ruth T; Tseng, Tiffany W; Sousa, Cristovao M; Liu, Sihao; Truitt, Morgan ... | P42ES010337 | Proc Natl Acad Sci U S A (2017 Jan 31) | 28096419 | 2017 |
Structural basis for specific ligation of the peroxisome proliferator-activated receptor δ. | Wu, Chyuan-Chuan; Baiga, Thomas J; Downes, Michael; La Clair, James J; Atkins, Annette R; Richa ... | P42ES010337 | Proc Natl Acad Sci U S A (2017 Mar 28) | 28320959 | 2017 |
Synectin promotes fibrogenesis by regulating PDGFR isoforms through distinct mechanisms. | Drinane, Mary C; Yaqoob, Usman; Yu, Haibin; Luo, Fanghong; Greuter, Thomas; Arab, Juan P; Kost ... | P42ES010337 | JCI Insight (2017 Dec 21) | 29263300 | 2017 |
The role of human cytochrome P450 2E1 in liver inflammation and fibrosis. | Xu, Jun; Ma, Hsiao-Yen; Liang, Shuang; Sun, Mengxi; Karin, Gabriel; Koyama, Yukinori; Hu, Ron ... | P42ES010337 | Hepatol Commun (2017 Dec) | 29404441 | 2017 |
TRIF Differentially Regulates Hepatic Steatosis and Inflammation/Fibrosis in Mice. | Yang, Ling; Miura, Kouichi; Zhang, Bi; Matsushita, Hiroshi; Yang, Yoon Mee; Liang, Shuang; Son ... | P42ES010337 | Cell Mol Gastroenterol Hepatol (2017 May) | 28462384 | 2017 |
A Novel Gonadotropin-Releasing Hormone 1 (Gnrh1) Enhancer-Derived Noncoding RNA Regulates Gnrh1 Gene ... | Huang, Polly P; Brusman, Liza E; Iyer, Anita K; Webster, Nicholas J G; Mellon, Pamela L | P42ES010337 | PLoS One (2016) | 27389022 | 2016 |
A small population of hypothalamic neurons govern fertility: the critical role of VAX1 in GnRH neuro ... | Hoffmann, Hanne M; Mellon, Pamela L | P42ES010337 | Neurosci Commun (Houst) (2016) | 28164172 | 2016 |
Acrolein, a New Villain in the Development of Alcoholic Liver Disease. | Seki, Ekihiro | P42ES010337 | Cell Mol Gastroenterol Hepatol (2016 Sep) | 28174735 | 2016 |
Acyl-glucuronide as a Possible Cause of Trovafloxacin-Induced Liver Toxicity: Induction of Chemokine ... | Mitsugi, Ryo; Sumida, Kyohei; Fujie, Yoshiko; Tukey, Robert H; Itoh, Tomoo; Fujiwara, Ryoichi | P42ES010337 | Biol Pharm Bull (2016) | 27725437 | 2016 |
An ABA-increased interaction of the PYL6 ABA receptor with MYC2 Transcription Factor: A putative lin ... | Aleman, Fernando; Yazaki, Junshi; Lee, Melissa; Takahashi, Yohei; Kim, Alice Y; Li, Zixing; Ki ... | P42ES010337 | Sci Rep (2016 Jun 30) | 27357749 | 2016 |
Bmal1 Is Required for Normal Reproductive Behaviors in Male Mice. | Schoeller, Erica L; Clark, Daniel D; Dey, Sandeepa; Cao, Nathan V; Semaan, Sheila J; Chao, Lin ... | P42ES010337 | Endocrinology (2016 Dec) | 27704948 | 2016 |
Cadmium and arsenic override NF-κB developmental regulation of the intestinal UGT1A1 gene and contro ... | Liu, Miao; Chen, Shujuan; Yueh, Mei-Fei; Fujiwara, Ryoichi; Konopnicki, Camille; Hao, Haiping; ... | P42ES010337 | Biochem Pharmacol (2016 Jun 15) | 27060662 | 2016 |
Cistromic and genetic evidence that the vitamin D receptor mediates susceptibility to latitude-depen ... | Booth, D R; Ding, N; Parnell, G P; Shahijanian, F; Coulter, S; Schibeci, S D; Atkins, A R; St ... | P42ES010337 | Genes Immun (2016 Jun) | 26986782 | 2016 |
CO2 Sensing and CO2 Regulation of Stomatal Conductance: Advances and Open Questions. | Engineer, Cawas B; Hashimoto-Sugimoto, Mimi; Negi, Juntaro; Israelsson-Nordström, Maria; Azoulay ... | P42ES010337 | Trends Plant Sci (2016 Jan) | 26482956 | 2016 |
Creating healthy and just bioregions. | Pezzoli, Keith; Leiter, Robert Allen | P42ES010337 | Rev Environ Health (2016 Mar) | 26812849 | 2016 |
Ctp1-dependent clipping and resection of DNA double-strand breaks by Mre11 endonuclease complex are ... | Jensen, Kristi L; Russell, Paul | P42ES010337 | Nucleic Acids Res (2016 Sep 30) | 27325741 | 2016 |
Deletion of Vax1 from Gonadotropin-Releasing Hormone (GnRH) Neurons Abolishes GnRH Expression and Le ... | Hoffmann, Hanne M; Trang, Crystal; Gong, Ping; Kimura, Ikuo; Pandolfi, Erica C; Mellon, Pamela ... | P42ES010337 | J Neurosci (2016 Mar 23) | 27013679 | 2016 |
Effective treatment of steatosis and steatohepatitis by fibroblast growth factor 1 in mouse models o ... | Liu, Weilin; Struik, Dicky; Nies, Vera J M; Jurdzinski, Angelika; Harkema, Liesbeth; de Bruin, ... | P42ES010337 | Proc Natl Acad Sci U S A (2016 Feb 23) | 26858440 | 2016 |
ERRγ Is Required for the Metabolic Maturation of Therapeutically Functional Glucose-Responsive β Cel ... | Yoshihara, Eiji; Wei, Zong; Lin, Chun Shi; Fang, Sungsoon; Ahmadian, Maryam; Kida, Yasuyuki; T ... | P42ES010337 | Cell Metab (2016 Apr 12) | 27076077 | 2016 |
Exosome Migration Inhibitory Factor as a Marker and Therapeutic Target for Pancreatic Cancer. | Matsushita, Hiroshi; Yang, Yoon Mee; Pandol, Stephen J; Seki, Ekihiro | P42ES010337 | Gastroenterology (2016 Apr) | 26922869 | 2016 |
Finding a new role for NEMO: A key player in preventing hepatocyte apoptosis and liver tumorigenesis ... | Hsin, I-Fang; Montano, Erica; Seki, Ekihiro | P42ES010337 | Hepatology (2016 Jul) | 27122117 | 2016 |
Global Fitness Profiling Identifies Arsenic and Cadmium Tolerance Mechanisms in Fission Yeast. | Guo, Lan; Ganguly, Abantika; Sun, Lingling; Suo, Fang; Du, Li-Lin; Russell, Paul | P42ES010337 | G3 (Bethesda) (2016 Oct 13) | 27558664 | 2016 |
Growth and the Environment of Schizosaccharomyces pombe. | Petersen, Janni; Russell, Paul | P42ES010337 | Cold Spring Harb Protoc (2016 Mar 01) | 26933253 | 2016 |
HEDGEHOG Signal in hepatocytes mediates macrophage recruitment: A new mechanism and potential therap ... | Seki, Ekihiro | P42ES010337 | Hepatology (2016 Apr) | 26638191 | 2016 |
Identification of AtOPT4 as a Plant Glutathione Transporter. | Zhang, Zhongchun; Xie, Qingqing; Jobe, Timothy O; Kau, Andrew R; Wang, Cun; Li, Yunxia; Qiu, ... | P42ES010337 | Mol Plant (2016 Mar 07) | 26283048 | 2016 |
Induction of the UDP-Glucuronosyltransferase 1A1 during the Perinatal Period Can Cause Neurodevelopm ... | Hirashima, Rika; Michimae, Hirofumi; Takemoto, Hiroaki; Sasaki, Aya; Kobayashi, Yoshinori; Itoh ... | P42ES010337 | Mol Pharmacol (2016 Sep) | 27413119 | 2016 |
Liver carcinogenesis: from naughty chemicals to soothing fat and the surprising role of NRF2. | Karin, Michael; Dhar, Debanjan | P42ES010337 | Carcinogenesis (2016 Jun) | 27207669 | 2016 |
Mapping transcription factor interactome networks using HaloTag protein arrays. | Yazaki, Junshi; Galli, Mary; Kim, Alice Y; Nito, Kazumasa; Aleman, Fernando; Chang, Katherine ... | P42ES010337 | Proc Natl Acad Sci U S A (2016 Jul 19) | 27357687 | 2016 |
New Developments on the Treatment of Liver Fibrosis. | Koyama, Yukinori; Xu, Jun; Liu, Xiao; Brenner, David A | P42ES010337 | Dig Dis (2016) | 27332862 | 2016 |
NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria. | Zhong, Zhenyu; Umemura, Atsushi; Sanchez-Lopez, Elsa; Liang, Shuang; Shalapour, Shabnam; Wong, ... | P42ES010337 | Cell (2016 Feb 25) | 26919428 | 2016 |
Nitrate-Regulated Glutaredoxins Control Arabidopsis Primary Root Growth. | Patterson, Kurt; Walters, Laura A; Cooper, Andrew M; Olvera, Jocelyn G; Rosas, Miguel A; Rasmus ... | P42ES010337 | Plant Physiol (2016 Feb) | 26662603 | 2016 |
Nonsense-Mediated RNA Decay Influences Human Embryonic Stem Cell Fate. | Lou, Chih-Hong; Chousal, Jennifer; Goetz, Alexandra; Shum, Eleen Y; Brafman, David; Liao, Xiao ... | P42ES010337 | Stem Cell Reports (2016 06 14) | 27304915 | 2016 |
Nuclear receptors and AMPK: can exercise mimetics cure diabetes? | Wall, Christopher E; Yu, Ruth T; Atkins, Anne R; Downes, Michael; Evans, Ronald M | P42ES010337 | J Mol Endocrinol (2016 Jul) | 27106806 | 2016 |
OsHKT1;4-mediated Na(+) transport in stems contributes to Na(+) exclusion from leaf blades of rice a ... | Suzuki, Kei; Yamaji, Naoki; Costa, Alex; Okuma, Eiji; Kobayashi, Natsuko I; Kashiwagi, Tatsuhi ... | P42ES010337 | BMC Plant Biol (2016 Jan 19) | 26786707 | 2016 |
p62 in Cancer: Signaling Adaptor Beyond Autophagy. | Moscat, Jorge; Karin, Michael; Diaz-Meco, Maria T | P42ES010337 | Cell (2016 Oct 20) | 27768885 | 2016 |
p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival ... | Umemura, Atsushi; He, Feng; Taniguchi, Koji; Nakagawa, Hayato; Yamachika, Shinichiro; Font-Burg ... | P42ES010337 | Cancer Cell (2016 06 13) | 27211490 | 2016 |
p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and L ... | Duran, Angeles; Hernandez, Eloy D; Reina-Campos, Miguel; Castilla, Elias A; Subramaniam, Shanka ... | P42ES010337 | Cancer Cell (2016 Oct 10) | 27728806 | 2016 |
p62/SQSTM1-Dr. Jekyll and Mr. Hyde that prevents oxidative stress but promotes liver cancer. | Taniguchi, Koji; Yamachika, Shinichiro; He, Feng; Karin, Michael | P42ES010337 | FEBS Lett (2016 08) | 27404485 | 2016 |
Promising Therapy Candidates for Liver Fibrosis. | Wang, Ping; Koyama, Yukinori; Liu, Xiao; Xu, Jun; Ma, Hsiao-Yen; Liang, Shuang; Kim, In H; Br ... | P42ES010337 | Front Physiol (2016) | 26909046 | 2016 |
Rapid hyperosmotic-induced Ca2+ responses in Arabidopsis thaliana exhibit sensory potentiation and i ... | Stephan, Aaron B; Kunz, Hans-Henning; Yang, Eric; Schroeder, Julian I | P42ES010337 | Proc Natl Acad Sci U S A (2016 Aug 30) | 27528686 | 2016 |
Reconstitution of CO2 Regulation of SLAC1 Anion Channel and Function of CO2-Permeable PIP2;1 Aquapor ... | Wang, Cun; Hu, Honghong; Qin, Xue; Zeise, Brian; Xu, Danyun; Rappel, Wouter-Jan; Boron, Walte ... | P42ES010337 | Plant Cell (2016 Feb) | 26764375 | 2016 |
Reduced Myelination and Increased Glia Reactivity Resulting from Severe Neonatal Hyperbilirubinemia. | Barateiro, Andreia; Chen, Shujuan; Yueh, Mei-Fei; Fernandes, Adelaide; Domingues, Helena Sofia; ... | P42ES010337 | Mol Pharmacol (2016 Jan) | 26480925 | 2016 |
Reduction of p53 by knockdown of the UGT1 locus in colon epithelial cells causes an increase in tumo ... | Liu, Miao; Chen, Shujuan; Yueh, Mei-Fei; Wang, Guangji; Hao, Haiping; Tukey, Robert H | P42ES010337 | Cell Mol Gastroenterol Hepatol (2016 Jan) | 26807433 | 2016 |
Reparative inflammation takes charge of tissue regeneration. | Karin, Michael; Clevers, Hans | P42ES010337 | Nature (2016 Jan 21) | 26791721 | 2016 |
Sestrin regulation of TORC1: Is Sestrin a leucine sensor? | Lee, Jun Hee; Cho, Uhn-Soo; Karin, Michael | P42ES010337 | Sci Signal (2016 Jun 07) | 27273098 | 2016 |
Stage-specific regulation of the WNT/β-catenin pathway enhances differentiation of hESCs into hepato ... | Touboul, Thomas; Chen, Shujuan; To, Cuong C; Mora-Castilla, Sergio; Sabatini, Karen; Tukey, Ro ... | P42ES010337 | J Hepatol (2016 Jun) | 26921690 | 2016 |
The Role of NADPH Oxidases (NOXs) in Liver Fibrosis and the Activation of Myofibroblasts. | Liang, Shuang; Kisseleva, Tatiana; Brenner, David A | P42ES010337 | Front Physiol (2016) | 26869935 | 2016 |
The Transmembrane Region of Guard Cell SLAC1 Channels Perceives CO2 Signals via an ABA-Independent P ... | Yamamoto, Yoshiko; Negi, Juntaro; Wang, Cun; Isogai, Yasuhiro; Schroeder, Julian I; Iba, Koh | P42ES010337 | Plant Cell (2016 Feb) | 26764376 | 2016 |
Triclosan: A Widespread Environmental Toxicant with Many Biological Effects. | Yueh, Mei-Fei; Tukey, Robert H | P42ES010337 | Annu Rev Pharmacol Toxicol (2016) | 26738475 | 2016 |
A Novel Letrozole Model Recapitulates Both the Reproductive and Metabolic Phenotypes of Polycystic O ... | Kauffman, Alexander S; Thackray, Varykina G; Ryan, Genevieve E; Tolson, Kristen P; Glidewell-Ken ... | P42ES010337 | Biol Reprod (2015 Sep) | 26203175 | 2015 |
Abscisic acid and other plant hormones: Methods to visualize distribution and signaling. | Waadt, Rainer; Hsu, Po-Kai; Schroeder, Julian I | P42ES010337 | Bioessays (2015 Dec) | 26577078 | 2015 |
Absent Progesterone Signaling in Kisspeptin Neurons Disrupts the LH Surge and Impairs Fertility in F ... | Stephens, Shannon B Z; Tolson, Kristen P; Rouse Jr, Melvin L; Poling, Matthew C; Hashimoto-Party ... | P42ES010337 | Endocrinology (2015 Sep) | 26076042 | 2015 |
Aging and liver disease. | Kim, In Hee; Kisseleva, Tatiana; Brenner, David A | P42ES010337 | Curr Opin Gastroenterol (2015 May) | 25850346 | 2015 |
Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER s ... | Antonucci, Laura; Fagman, Johan B; Kim, Ju Youn; Todoric, Jelena; Gukovsky, Ilya; Mackey, Maso ... | P42ES010337 | Proc Natl Acad Sci U S A (2015 Nov 10) | 26512112 | 2015 |
BRD4 is a novel therapeutic target for liver fibrosis. | Ding, Ning; Hah, Nasun; Yu, Ruth T; Sherman, Mara H; Benner, Chris; Leblanc, Mathias; He, Min ... | P42ES010337 | Proc Natl Acad Sci U S A (2015 Dec 22) | 26644586 | 2015 |
Calcipotriol Targets LRP6 to Inhibit Wnt Signaling in Pancreatic Cancer. | Arensman, Michael D; Nguyen, Phillip; Kershaw, Kathleen M; Lay, Anna R; Ostertag-Hill, Claire A ... | P42ES010337 | Mol Cancer Res (2015 Nov) | 26224368 | 2015 |
Calcium specificity signaling mechanisms in abscisic acid signal transduction in Arabidopsis guard c ... | Brandt, Benjamin; Munemasa, Shintaro; Wang, Cun; Nguyen, Desiree; Yong, Taiming; Yang, Paul G; ... | P42ES010337 | Elife (2015 Jul 20) | 26192964 | 2015 |
Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice. | Mazagova, Magdalena; Wang, Lirui; Anfora, Andrew T; Wissmueller, Max; Lesley, Scott A; Miyamoto ... | P42ES010337 | FASEB J (2015 Mar) | 25466902 | 2015 |
Comment on 'Fluorescence sensing of arsenate at nanomolar level in a greener way: naphthalene based ... | Liu, Yuanli; Trogler, William C | P42ES010337 | Chem Commun (Camb) (2015 Oct 11) | 26299989 | 2015 |
Corrigendum: Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer. | Suh, Jae Myoung; Jonker, Johan W; Ahmadian, Maryam; Goetz, Regina; Lackey, Denise; Osborn, Oli ... | P42ES010337 | Nature (2015 Apr 16) | 25739500 | 2015 |
Critical Function of γH2A in S-Phase. | Mejia-Ramirez, Eva; Limbo, Oliver; Langerak, Petra; Russell, Paul | P42ES010337 | PLoS Genet (2015 Sep) | 26368543 | 2015 |
Deficiency of NOX1 or NOX4 Prevents Liver Inflammation and Fibrosis in Mice through Inhibition of He ... | Lan, Tian; Kisseleva, Tatiana; Brenner, David A | P42ES010337 | PLoS One (2015) | 26222337 | 2015 |
Depletion of fat-resident Treg cells prevents age-associated insulin resistance. | Bapat, Sagar P; Myoung Suh, Jae; Fang, Sungsoon; Liu, Sihao; Zhang, Yang; Cheng, Albert; Zhou, ... | P42ES010337 | Nature (2015 Dec 03) | 26580014 | 2015 |
Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular car ... | Finkin, Shlomi; Yuan, Detian; Stein, Ilan; Taniguchi, Koji; Weber, Achim; Unger, Kristian; Bro ... | P42ES010337 | Nat Immunol (2015 Dec) | 26502405 | 2015 |
Effect of weight loss on magnetic resonance imaging estimation of liver fat and volume in patients w ... | Patel, Niraj S; Doycheva, Iliana; Peterson, Michael R; Hooker, Jonathan; Kisselva, Tatiana; Sch ... | P42ES010337 | Clin Gastroenterol Hepatol (2015 Mar) | 25218667 | 2015 |
Expression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Su ... | Kutsuno, Yuki; Hirashima, Rika; Sakamoto, Masaya; Ushikubo, Hiroko; Michimae, Hirofumi; Itoh, ... | P42ES010337 | Drug Metab Dispos (2015 Jul) | 25953521 | 2015 |
Genetic Interaction Landscape Reveals Critical Requirements for Schizosaccharomyces pombe Brc1 in DN ... | Sánchez, Arancha; Roguev, Assen; Krogan, Nevan J; Russell, Paul | P42ES010337 | G3 (Bethesda) (2015 Mar 19) | 25795664 | 2015 |
Guard cell photosynthesis is critical for stomatal turgor production, yet does not directly mediate ... | Azoulay-Shemer, Tamar; Palomares, Axxell; Bagheri, Andisheh; Israelsson-Nordstrom, Maria; Engine ... | P42ES010337 | Plant J (2015 Aug) | 26096271 | 2015 |
Hepatic inflammation and fibrosis: functional links and key pathways. | Seki, Ekihiro; Schwabe, Robert F | P42ES010337 | Hepatology (2015 Mar) | 25066777 | 2015 |
Homeodomain Proteins SIX3 and SIX6 Regulate Gonadotrope-specific Genes During Pituitary Development. | Xie, Huimin; Hoffmann, Hanne M; Meadows, Jason D; Mayo, Susan L; Trang, Crystal; Leming, Sunam ... | P42ES010337 | Mol Endocrinol (2015 Jun) | 25915183 | 2015 |
Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer. | Font-Burgada, Joan; Shalapour, Shabnam; Ramaswamy, Suvasini; Hsueh, Brian; Rossell, David; Umem ... | P42ES010337 | Cell (2015 Aug 13) | 26276631 | 2015 |
Imaging Fibrosis and Separating Collagens using Second Harmonic Generation and Phasor Approach to Fl ... | Ranjit, Suman; Dvornikov, Alexander; Stakic, Milka; Hong, Suk-Hyun; Levi, Moshe; Evans, Ronald ... | P42ES010337 | Sci Rep (2015 Aug 21) | 26293987 | 2015 |
Inflammation-sensitive super enhancers form domains of coordinately regulated enhancer RNAs. | Hah, Nasun; Benner, Chris; Chong, Ling-Wa; Yu, Ruth T; Downes, Michael; Evans, Ronald M | P42ES010337 | Proc Natl Acad Sci U S A (2015 Jan 20) | 25564661 | 2015 |
Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance. | Fang, Sungsoon; Suh, Jae Myoung; Reilly, Shannon M; Yu, Elizabeth; Osborn, Olivia; Lackey, Den ... | P42ES010337 | Nat Med (2015 Feb) | 25559344 | 2015 |
Live Cell Imaging with R-GECO1 Sheds Light on flg22- and Chitin-Induced Transient [Ca(2+)]cyt Patter ... | Keinath, Nana F; Waadt, Rainer; Brugman, Rik; Schroeder, Julian I; Grossmann, Guido; Schumacher ... | P42ES010337 | Mol Plant (2015 Aug) | 26002145 | 2015 |
MafG, A Novel Target of FXR that Regulates Bile Acid Homeostasis. | Yang, Yoon Mee; Roh, Yoon Seok; Seki, Ekihiro | P42ES010337 | Gastroenterology (2015 Dec) | 26501563 | 2015 |
Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to ... | Bourne, Yves; Sulzenbacher, Gerlind; Radić, Zoran; Aráoz, Rómulo; Reynaud, Morgane; Benoit, Ev ... | P42ES010337 | Structure (2015 Jun 02) | 26004441 | 2015 |
Mechanisms of abscisic acid-mediated control of stomatal aperture. | Munemasa, Shintaro; Hauser, Felix; Park, Jiyoung; Waadt, Rainer; Brandt, Benjamin; Schroeder, ... | P42ES010337 | Curr Opin Plant Biol (2015 Dec) | 26599955 | 2015 |
New therapies for hepatic fibrosis. | Koyama, Yukinori; Brenner, David A | P42ES010337 | Clin Res Hepatol Gastroenterol (2015 Sep) | 26206573 | 2015 |
Nicotine regulates the expression of UDP-glucuronosyltransferase (UGT) in humanized UGT1 mouse brain ... | Sakamoto, Masaya; Itoh, Tomoo; Tukey, Robert H; Fujiwara, Ryoichi | P42ES010337 | Drug Metab Pharmacokinet (2015 Aug) | 26210671 | 2015 |
P16INK4a Upregulation Mediated by SIX6 Defines Retinal Ganglion Cell Pathogenesis in Glaucoma. | Skowronska-Krawczyk, Dorota; Zhao, Ling; Zhu, Jie; Weinreb, Robert N; Cao, Guiqun; Luo, Jing; ... | P42ES010337 | Mol Cell (2015 Sep 17) | 26365380 | 2015 |
PPARs and ERRs: molecular mediators of mitochondrial metabolism. | Fan, Weiwei; Evans, Ronald | P42ES010337 | Curr Opin Cell Biol (2015 Apr) | 25486445 | 2015 |
Recent advancement of molecular mechanisms of liver fibrosis. | Seki, Ekihiro; Brenner, David A | P42ES010337 | J Hepatobiliary Pancreat Sci (2015 Jul) | 25869468 | 2015 |
Role of extrahepatic UDP-glucuronosyltransferase 1A1: Advances in understanding breast milk-induced ... | Fujiwara, Ryoichi; Maruo, Yoshihiro; Chen, Shujuan; Tukey, Robert H | P42ES010337 | Toxicol Appl Pharmacol (2015 Nov 15) | 26342858 | 2015 |
Role of Gut Microbiota in Liver Disease. | Brenner, David A; Paik, Yong-Han; Schnabl, Bernd | P42ES010337 | J Clin Gastroenterol (2015) | 26447960 | 2015 |
The NIEHS Superfund Research Program: 25 Years of Translational Research for Public Health. | Landrigan, Philip J; Wright, Robert O; Cordero, Jose F; Eaton, David L; Goldstein, Bernard D; H ... | P42ES004940, P42ES010337, P42ES017198 | Environ Health Perspect (2015 Oct) | 25978799 | 2015 |
The TM6SF2 variants, novel genetic predictors for nonalcoholic steatohepatitis. | Roh, Yoon-Seok; Loomba, Rohit; Seki, Ekihiro | P42ES010337 | Gastroenterology (2015 Jan) | 25451657 | 2015 |
TNFα in liver fibrosis. | Yang, Yoon Mee; Seki, Ekihiro | P42ES010337 | Curr Pathobiol Rep (2015 Dec) | 26726307 | 2015 |
A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic ... | Moles, Anna; Murphy, Lindsay; Wilson, Caroline L; Chakraborty, Jayashree Bagchi; Fox, Christoph ... | P42ES010337 | J Hepatol (2014 Apr) | 24333183 | 2014 |
Bilirubin uridine diphosphate-glucuronosyltransferase variation is a genetic basis of breast milk ja ... | Maruo, Yoshihiro; Morioka, Yoriko; Fujito, Hiroshi; Nakahara, Sayuri; Yanagi, Takahide; Matsui, ... | P42ES010337 | J Pediatr (2014 Jul) | 24650397 | 2014 |
Carbonic anhydrases, EPF2 and a novel protease mediate CO2 control of stomatal development. | Engineer, Cawas B; Ghassemian, Majid; Anderson, Jeffrey C; Peck, Scott C; Hu, Honghong; Schroed ... | P42ES010337 | Nature (2014 Sep 11) | 25043023 | 2014 |
Cerium oxide nanoparticles protect against Aβ-induced mitochondrial fragmentation and neuronal cell ... | Dowding, J M; Song, W; Bossy, K; Karakoti, A; Kumar, A; Kim, A; Bossy, B; Seal, S; Ellisman, ... | P42ES010337 | Cell Death Differ (2014 Oct) | 24902900 | 2014 |
Developmental onset of bilirubin-induced neurotoxicity involves Toll-like receptor 2-dependent signa ... | Yueh, Mei-Fei; Chen, Shujuan; Nguyen, Nghia; Tukey, Robert H | P42ES010337 | J Biol Chem (2014 Feb 21) | 24403077 | 2014 |
Differences in health symptoms among residents living near illegal dump sites in Los Laureles Canyon ... | Al-Delaimy, Wael K; Larsen, Catherine Wood; Pezzoli, Keith | P42ES010337 | Int J Environ Res Public Health (2014 Sep) | 25226411 | 2014 |
Effects of exogenous pyoverdines on Fe availability and their impacts on Mn(II) oxidation by Pseudom ... | Lee, Sung-Woo; Parker, Dorothy L; Geszvain, Kati; Tebo, Bradley M | P42ES010337 | Front Microbiol (2014) | 25009534 | 2014 |
Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer. | Suh, Jae Myoung; Jonker, Johan W; Ahmadian, Maryam; Goetz, Regina; Lackey, Denise; Osborn, Oli ... | P42ES010337 | Nature (2014 Sep 18) | 25043058 | 2014 |
ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development. | Nakagawa, Hayato; Umemura, Atsushi; Taniguchi, Koji; Font-Burgada, Joan; Dhar, Debanjan; Ogata, ... | P42ES010337 | Cancer Cell (2014 Sep 08) | 25132496 | 2014 |
FRET-based reporters for the direct visualization of abscisic acid concentration changes and distrib ... | Waadt, Rainer; Hitomi, Kenichi; Nishimura, Noriyuki; Hitomi, Chiharu; Adams, Stephen R; Getzoff ... | P42ES010337 | Elife (2014) | 24737861 | 2014 |
GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis. | Lopez-Sanchez, Inmaculada; Dunkel, Ying; Roh, Yoon-Seok; Mittal, Yash; De Minicis, Samuele; Mur ... | P42ES010337 | Nat Commun (2014 Jul 21) | 25043713 | 2014 |
Glucose induces intestinal human UDP-glucuronosyltransferase (UGT) 1A1 to prevent neonatal hyperbili ... | Aoshima, Naoya; Fujie, Yoshiko; Itoh, Tomoo; Tukey, Robert H; Fujiwara, Ryoichi | P42ES010337 | Sci Rep (2014) | 25209391 | 2014 |
Glucuronidation of drugs and drug-induced toxicity in humanized UDP-glucuronosyltransferase 1 mice. | Kutsuno, Yuki; Itoh, Tomoo; Tukey, Robert H; Fujiwara, Ryoichi | P42ES010337 | Drug Metab Dispos (2014 Jul) | 24764149 | 2014 |
Heterozygous deletion of ventral anterior homeobox (vax1) causes subfertility in mice. | Hoffmann, Hanne M; Tamrazian, Anika; Xie, Huimin; Pérez-Millán, María Inés; Kauffman, Alexander ... | P42ES010337 | Endocrinology (2014 Oct) | 25060364 | 2014 |
Influence of stress-induced intermediates on gonadotropin gene expression in gonadotrope cells. | Breen, Kellie M; Mellon, Pamela L | P42ES010337 | Mol Cell Endocrinol (2014 Mar 25) | 24012628 | 2014 |
Interactions between the intestinal microbiome and liver diseases. | Schnabl, Bernd; Brenner, David A | P42ES010337 | Gastroenterology (2014 May) | 24440671 | 2014 |
KISS1R signals independently of Gαq/11 and triggers LH secretion via the β-arrestin pathway in the m ... | Ahow, Maryse; Min, Le; Pampillo, Macarena; Nash, Connor; Wen, Junping; Soltis, Kathleen; Carro ... | P42ES010337 | Endocrinology (2014 Nov) | 25147978 | 2014 |
Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition. | Umemura, Atsushi; Park, Eek Joong; Taniguchi, Koji; Lee, Jun Hee; Shalapour, Shabnam; Valasek, ... | P42ES010337 | Cell Metab (2014 Jul 01) | 24910242 | 2014 |
Mechanisms of vascular dysfunction in mice with endothelium-specific deletion of the PPAR-δ gene. | d'Uscio, Livius V; He, Tongrong; Santhanam, Anantha Vijay R; Tai, Li-Jung; Evans, Ronald M; Kat ... | P42ES010337 | Am J Physiol Heart Circ Physiol (2014 Apr 01) | 24486511 | 2014 |
Microbiome-obesity-liver cancer interaction: senescence of hepatic stellate cells and bile acids pla ... | Seki, Ekihiro | P42ES010337 | Gastroenterology (2014 Mar) | 24468171 | 2014 |
NCOA5, IL-6, type 2 diabetes, and HCC: The deadly quartet. | Dhar, Debanjan; Seki, Ekihiro; Karin, Michael | P42ES010337 | Cell Metab (2014 Jan 07) | 24411937 | 2014 |
Neurokinin B induces c-fos transcription via protein kinase C and activation of serum response facto ... | Glidewell-Kenney, Christine A; Trang, Crystal; Shao, Paul P; Gutierrez-Reed, Navarre; Uzo-Okerek ... | P42ES010337 | Endocrinology (2014 Oct) | 25057795 | 2014 |
Novel fate-tracing strategies show that hepatic stellate cells mediate fibrosis in vivo. | Liang, Shuang; Zhong, Zhenyu; Seki, Ekihiro | P42ES010337 | Gastroenterology (2014 Jun) | 24768331 | 2014 |
Nrf2 activation protects the liver from ischemia/reperfusion injury in mice. | Kudoh, Kazuhiro; Uchinami, Hiroshi; Yoshioka, Masato; Seki, Ekihiro; Yamamoto, Yuzo | P42ES010337 | Ann Surg (2014 Jul) | 24368646 | 2014 |
Nuclear receptors and metabolism: from feast to famine. | Hong, Suk-Hyun; Ahmadian, Maryam; Yu, Ruth T; Atkins, Annette R; Downes, Michael; Evans, Ronal ... | P42ES010337 | Diabetologia (2014 May) | 24619218 | 2014 |
Nuclear receptors rock around the clock. | Zhao, Xuan; Cho, Han; Yu, Ruth T; Atkins, Annette R; Downes, Michael; Evans, Ronald M | P42ES010337 | EMBO Rep (2014 May) | 24737872 | 2014 |
Nuclear Receptors, RXR, and the Big Bang. | Evans, Ronald M; Mangelsdorf, David J | P42ES010337 | Cell (2014 Mar 27) | 24679540 | 2014 |
One Bioregion/One Health: An Integrative Narrative for Transboundary Planning along the US-Mexico Bo ... | Pezzoli, Keith; Kozo, Justine; Ferran, Karen; Wooten, Wilma; Gomez, Gudelia Rangel; Al-Delaimy, ... | P42ES010337 | Glob Soc (2014) | 26097402 | 2014 |
OPT3 is a component of the iron-signaling network between leaves and roots and misregulation of OPT3 ... | Mendoza-Cózatl, David G; Xie, Qingqing; Akmakjian, Garo Z; Jobe, Timothy O; Patel, Ami; Stacey, ... | P42ES010337 | Mol Plant (2014 Sep) | 24880337 | 2014 |
Phytochelatin-metal(loid) transport into vacuoles shows different substrate preferences in barley an ... | Song, Won-Yong; Mendoza-Cózatl, David G; Lee, Youngsook; Schroeder, Julian I; Ahn, Sang-Nag; Le ... | P42ES010337 | Plant Cell Environ (2014 May) | 24313707 | 2014 |
Plant salt stress status is transmitted systemically via propagating calcium waves. | Stephan, Aaron B; Schroeder, Julian I | P42ES010337 | Proc Natl Acad Sci U S A (2014 Apr 29) | 24737890 | 2014 |
Plant salt-tolerance mechanisms. | Deinlein, Ulrich; Stephan, Aaron B; Horie, Tomoaki; Luo, Wei; Xu, Guohua; Schroeder, Julian I | P42ES010337 | Trends Plant Sci (2014 Jun) | 24630845 | 2014 |
Plastidial transporters KEA1, -2, and -3 are essential for chloroplast osmoregulation, integrity, an ... | Kunz, Hans-Henning; Gierth, Markus; Herdean, Andrei; Satoh-Cruz, Mio; Kramer, David M; Spetea, ... | P42ES010337 | Proc Natl Acad Sci U S A (2014 May 20) | 24794527 | 2014 |
Pyoverdine synthesis by the Mn(II)-oxidizing bacterium Pseudomonas putida GB-1. | Parker, Dorothy L; Lee, Sung-Woo; Geszvain, Kati; Davis, Richard E; Gruffaz, Christelle; Meyer, ... | P42ES010337 | Front Microbiol (2014) | 24847318 | 2014 |
Regulation of the Rhp26ERCC6/CSB chromatin remodeler by a novel conserved leucine latch motif. | Wang, Lanfeng; Limbo, Oliver; Fei, Jia; Chen, Lu; Kim, Bong; Luo, Jie; Chong, Jenny; Conaway, ... | P42ES010337 | Proc Natl Acad Sci U S A (2014 Dec 30) | 25512493 | 2014 |
Role of NADPH oxidases in liver fibrosis. | Paik, Yong-Han; Kim, Jonghwa; Aoyama, Tomonori; De Minicis, Samuele; Bataller, Ramon; Brenner, ... | P42ES010337 | Antioxid Redox Signal (2014 Jun 10) | 24040957 | 2014 |
Roles of binding elements, FOXL2 domains, and interactions with cJUN and SMADs in regulation of FSHβ ... | Roybal, Lacey L; Hambarchyan, Arpi; Meadows, Jason D; Barakat, Nermeen H; Pepa, Patricia A; Bre ... | P42ES010337 | Mol Endocrinol (2014 Oct) | 25105693 | 2014 |
Self-assembled Targeting of Cancer Cells by Iron(III)-doped, Silica Nanoparticles. | Mitchell, K K Pohaku; Sandoval, S; Cortes-Mateos, M J; Alfaro, J G; Kummel, A C; Trogler, W C | P42ES010337 | J Mater Chem B (2014 Dec 07) | 25364507 | 2014 |
Sestrins inhibit mTORC1 kinase activation through the GATOR complex. | Parmigiani, Anita; Nourbakhsh, Aida; Ding, Boxiao; Wang, Wei; Kim, Young Chul; Akopiants, Kons ... | P42ES010337 | Cell Rep (2014 Nov 20) | 25457612 | 2014 |
Synthesis and surface functionalization of silica nanoparticles for nanomedicine. | Liberman, Alexander; Mendez, Natalie; Trogler, William C; Kummel, Andrew C | P42ES010337 | Surf Sci Rep (2014 Sep) | 25364083 | 2014 |
TAK1 regulates hepatic cell survival and carcinogenesis. | Roh, Yoon Seok; Song, Jingyi; Seki, Ekihiro | P42ES010337 | J Gastroenterol (2014 Feb) | 24443058 | 2014 |
TAK1-dependent autophagy: A suppressor of fatty liver disease and hepatic oncogenesis. | Seki, Ekihiro | P42ES010337 | Mol Cell Oncol (2014) | 26709386 | 2014 |
TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis. | Inokuchi-Shimizu, Sayaka; Park, Eek Joong; Roh, Yoon Seok; Yang, Ling; Zhang, Bi; Song, Jingyi ... | P42ES010337 | J Clin Invest (2014 Aug) | 24983318 | 2014 |
The commonly used antimicrobial additive triclosan is a liver tumor promoter. | Yueh, Mei-Fei; Taniguchi, Koji; Chen, Shujuan; Evans, Ronald M; Hammock, Bruce D; Karin, Micha ... | P42ES004699, P42ES010337 | Proc Natl Acad Sci U S A (2014 Dec 02) | 25404284 | 2014 |
Toll-like receptor 7-mediated type I interferon signaling prevents cholestasis- and hepatotoxin-indu ... | Roh, Yoon Seok; Park, Surim; Kim, Jong Won; Lim, Chae Woong; Seki, Ekihiro; Kim, Bumseok | P42ES010337 | Hepatology (2014 Jul) | 24375615 | 2014 |
Transcriptional repression of the transforming growth factor β (TGF-β) Pseudoreceptor BMP and activi ... | Liu, Cheng; Chen, Xiaorong; Yang, Ling; Kisseleva, Tatiana; Brenner, David A; Seki, Ekihiro | P42ES010337 | J Biol Chem (2014 Mar 07) | 24448807 | 2014 |
Transforming growth factor beta signaling in hepatocytes participates in steatohepatitis through reg ... | Yang, Ling; Roh, Yoon Seok; Song, Jingyi; Zhang, Bi; Liu, Cheng; Loomba, Rohit; Seki, Ekihiro | P42ES010337 | Hepatology (2014 Feb) | 23996730 | 2014 |
Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic ca ... | Sherman, Mara H; Yu, Ruth T; Engle, Dannielle D; Ding, Ning; Atkins, Annette R; Tiriac, Herve; ... | P42ES010337 | Cell (2014 Sep 25) | 25259922 | 2014 |
A genomic-scale artificial microRNA library as a tool to investigate the functionally redundant gene ... | Hauser, Felix; Chen, Wenxiao; Deinlein, Ulrich; Chang, Kenneth; Ossowski, Stephan; Fitz, Joffr ... | P42ES010337 | Plant Cell (2013 Aug) | 23956262 | 2013 |
A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response. | Ding, Ning; Yu, Ruth T; Subramaniam, Nanthakumar; Sherman, Mara H; Wilson, Caroline; Rao, Renu ... | P42ES010337 | Cell (2013 Apr 25) | 23622244 | 2013 |
Aberrant development of the suprachiasmatic nucleus and circadian rhythms in mice lacking the homeod ... | Clark, Daniel D; Gorman, Michael R; Hatori, Megumi; Meadows, Jason D; Panda, Satchidananda; Mel ... | P42ES010337 | J Biol Rhythms (2013 Feb) | 23382588 | 2013 |
DIDS (4,4-diisothiocyanatostilbenedisulphonic acid) induces apoptotic cell death in a hippocampal ne ... | Pamenter, Matthew E; Perkins, Guy A; Gu, Xiang Q; Ellisman, Mark H; Haddad, Gabriel G | P42ES010337 | PLoS One (2013) | 23577164 | 2013 |
Elemental concentrations in the seed of mutants and natural variants of Arabidopsis thaliana grown u ... | McDowell, Stephen C; Akmakjian, Garo; Sladek, Chris; Mendoza-Cozatl, David; Morrissey, Joe B; S ... | P42ES010337 | PLoS One (2013) | 23671651 | 2013 |
Elimination of manganese(II,III) oxidation in Pseudomonas putida GB-1 by a double knockout of two pu ... | Geszvain, Kati; McCarthy, James K; Tebo, Bradley M | P42ES010337 | Appl Environ Microbiol (2013 Jan) | 23124227 | 2013 |
Evaluation of UGT protein interactions in human hepatocytes: effect of siRNA down regulation of UGT1 ... | Konopnicki, Camille M; Dickmann, Leslie J; Tracy, Jeffrey M; Tukey, Robert H; Wienkers, Larry C ... | P42ES010337 | Arch Biochem Biophys (2013 Jul 15) | 23562620 | 2013 |
Evidence for orphan nuclear receptor TR4 in the etiology of Cushing disease. | Du, Li; Bergsneider, Marvin; Mirsadraei, Leili; Young, Steven H; Jonker, Johan W; Downes, Mich ... | P42ES010337 | Proc Natl Acad Sci U S A (2013 May 21) | 23653479 | 2013 |
Gene dosage of Otx2 is important for fertility in male mice. | Larder, Rachel; Kimura, Ikuo; Meadows, Jason; Clark, Daniel D; Mayo, Susan; Mellon, Pamela L | P42ES010337 | Mol Cell Endocrinol (2013 Sep 05) | 23811236 | 2013 |
Hepatic actions of vitamin D receptor ligands: a sunshine option for chronic liver disease? | Ding, Ning; Liddle, Christopher; Evans, Ronald M; Downes, Michael | P42ES010337 | Expert Rev Clin Pharmacol (2013 Nov) | 24164608 | 2013 |
Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 sig ... | He, Guobin; Dhar, Debanjan; Nakagawa, Hayato; Font-Burgada, Joan; Ogata, Hisanobu; Jiang, Yuho ... | P42ES010337 | Cell (2013 Oct 10) | 24120137 | 2013 |
Identification of three novel natural product compounds that activate PXR and CAR and inhibit inflam ... | Kittayaruksakul, Suticha; Zhao, Wenchen; Xu, Meishu; Ren, Songrong; Lu, Jing; Wang, Ju; Downes ... | P42ES010337 | Pharm Res (2013 Sep) | 23896737 | 2013 |
Impact of fatty acids on human UDP-glucuronosyltransferase 1A1 activity and its expression in neonat ... | Shibuya, Ayako; Itoh, Tomoo; Tukey, Robert H; Fujiwara, Ryoichi | P42ES010337 | Sci Rep (2013) | 24104695 | 2013 |
Importance of UDP-glucuronosyltransferase 1A1 expression in skin and its induction by UVB in neonata ... | Sumida, Kyohei; Kawana, Makiko; Kouno, Emi; Itoh, Tomoo; Takano, Shuhei; Narawa, Tomoya; Tukey ... | P42ES010337 | Mol Pharmacol (2013 Nov) | 23950218 | 2013 |
Insights into negative regulation by the glucocorticoid receptor from genome-wide profiling of infla ... | Uhlenhaut, N Henriette; Barish, Grant D; Yu, Ruth T; Downes, Michael; Karunasiri, Malith; Liddl ... | P42ES010337 | Mol Cell (2013 Jan 10) | 23159735 | 2013 |
Intestinal glucuronidation protects against chemotherapy-induced toxicity by irinotecan (CPT-11). | Chen, Shujuan; Yueh, Mei-Fei; Bigo, Cyril; Barbier, Olivier; Wang, Kepeng; Karin, Michael; Ngu ... | P42ES010337 | Proc Natl Acad Sci U S A (2013 Nov 19) | 24191041 | 2013 |
JNK inhibition reduces apoptosis and neovascularization in a murine model of age-related macular deg ... | Du, Hongjun; Sun, Xufang; Guma, Monica; Luo, Jing; Ouyang, Hong; Zhang, Xiaohui; Zeng, Jing; ... | P42ES010337 | Proc Natl Acad Sci U S A (2013 Feb 5) | 23341606 | 2013 |
Kisspeptin regulates gonadotropin genes via immediate early gene induction in pituitary gonadotropes ... | Witham, Emily A; Meadows, Jason D; Hoffmann, Hanne M; Shojaei, Shadi; Coss, Djurdjica; Kauffman ... | P42ES010337 | Mol Endocrinol (2013 Aug) | 23770611 | 2013 |
M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pat ... | Madsen, Daniel H; Leonard, Daniel; Masedunskas, Andrius; Moyer, Amanda; Jürgensen, Henrik Jesse ... | P42ES010337 | J Cell Biol (2013 Sep 16) | 24019537 | 2013 |
Msx1 homeodomain protein represses the αGSU and GnRH receptor genes during gonadotrope development. | Xie, Huimin; Cherrington, Brian D; Meadows, Jason D; Witham, Emily A; Mellon, Pamela L | P42ES010337 | Mol Endocrinol (2013 Mar) | 23371388 | 2013 |
Neurokinin B causes acute GnRH secretion and repression of GnRH transcription in GT1-7 GnRH neurons. | Glidewell-Kenney, Christine A; Shao, Paul P; Iyer, Anita K; Grove, Anna M H; Meadows, Jason D; ... | P42ES010337 | Mol Endocrinol (2013 Mar) | 23393128 | 2013 |
p38α inhibits liver fibrogenesis and consequent hepatocarcinogenesis by curtailing accumulation of r ... | Sakurai, Toshiharu; Kudo, Masatoshi; Umemura, Atsushi; He, Guobin; Elsharkawy, Ahmed M; Seki, ... | P42ES010337 | Cancer Res (2013 Jan 01) | 23271722 | 2013 |
PPARγ signaling and metabolism: the good, the bad and the future. | Ahmadian, Maryam; Suh, Jae Myoung; Hah, Nasun; Liddle, Christopher; Atkins, Annette R; Downes, ... | P42ES010337 | Nat Med (2013 May) | 23652116 | 2013 |
Road to exercise mimetics: targeting nuclear receptors in skeletal muscle. | Fan, Weiwei; Atkins, Annette R; Yu, Ruth T; Downes, Michael; Evans, Ronald M | P42ES010337 | J Mol Endocrinol (2013 Dec) | 24280961 | 2013 |
Sestrins orchestrate cellular metabolism to attenuate aging. | Lee, Jun Hee; Budanov, Andrei V; Karin, Michael | P42ES010337 | Cell Metab (2013 Dec 03) | 24055102 | 2013 |
The effect of Ca2+ ions and ionic strength on Mn(II) oxidation by spores of the marine Bacillus sp. ... | Toyoda, Kazuhiro; Tebo, Bradley M | P42ES010337 | Geochim Cosmochim Acta (2013 Jan 15) | 29176910 | 2013 |
Toll-like receptors in alcoholic liver disease, non-alcoholic steatohepatitis and carcinogenesis. | Roh, Yoon Seok; Seki, Ekihiro | P42ES010337 | J Gastroenterol Hepatol (2013 Aug) | 23855294 | 2013 |
Transforming growth factor-β signaling in hepatocytes promotes hepatic fibrosis and carcinogenesis i ... | Yang, Ling; Inokuchi, Sayaka; Roh, Yoon Seok; Song, Jingyi; Loomba, Rohit; Park, Eek Joong; Se ... | P42ES010337 | Gastroenterology (2013 May) | 23391818 | 2013 |
Using membrane transporters to improve crops for sustainable food production. | Schroeder, Julian I; Delhaize, Emmanuel; Frommer, Wolf B; Guerinot, Mary Lou; Harrison, Maria J ... | P42ES010337 | Nature (2013 May 02) | 23636397 | 2013 |
A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical ... | Seki, Ekihiro; Brenner, David A; Karin, Michael | P42ES010337 | Gastroenterology (2012 Aug) | 22705006 | 2012 |
Androgen receptor repression of GnRH gene transcription. | Brayman, Melissa J; Pepa, Patricia A; Berdy, Sara E; Mellon, Pamela L | P42ES010337 | Mol Endocrinol (2012 Jan) | 22074952 | 2012 |
Androgen receptor repression of gonadotropin-releasing hormone gene transcription via enhancer 1. | Brayman, Melissa J; Pepa, Patricia A; Mellon, Pamela L | P42ES010337 | Mol Cell Endocrinol (2012 Nov 05) | 22877652 | 2012 |
Arsenic decreases RXRα-dependent transcription of CYP3A and suppresses immune regulators in hepatocy ... | Noreault-Conti, Trisha L; Fellows, Abigail; Jacobs, Judith M; Trask, Heidi W; Strom, Stephen C; ... | P42ES010337 | Int Immunopharmacol (2012 Apr) | 22310326 | 2012 |
Bcl-xL-mediated remodeling of rod and cone synaptic mitochondria after postnatal lead exposure: elec ... | Perkins, Guy A; Scott, Ray; Perez, Alex; Ellisman, Mark H; Johnson, Jerry E; Fox, Donald A | P42ES010337 | Mol Vis (2012) | 23288995 | 2012 |
Cadmium-induced proteome remodeling regulated by Spc1/Sty1 and Zip1 in fission yeast. | Guo, Lan; Ghassemian, Majid; Komives, Elizabeth A; Russell, Paul | P42ES010337 | Toxicol Sci (2012 Sep) | 22610605 | 2012 |
Congenital hypothyroidism mutations affect common folding and trafficking in the α/β-hydrolase fold ... | De Jaco, Antonella; Dubi, Noga; Camp, Shelley; Taylor, Palmer | P42ES010337 | FEBS J (2012 Dec) | 23035660 | 2012 |
CYLD and HCC: when being too sensitive to your dirty neighbors results in self-destruction. | Font-Burgada, Joan; Seki, Ekihiro; Karin, Michael | P42ES010337 | Cancer Cell (2012 Jun 12) | 22698394 | 2012 |
Feedback inhibition by thiols outranks glutathione depletion: a luciferase-based screen reveals glut ... | Jobe, Timothy O; Sung, Dong-Yul; Akmakjian, Garo; Pham, Allis; Komives, Elizabeth A; Mendoza-Có ... | P42ES010337 | Plant J (2012 Jun) | 22283708 | 2012 |
FOXL2 is involved in the synergy between activin and progestins on the follicle-stimulating hormone ... | Ghochani, Yasmin; Saini, Jasjit K; Mellon, Pamela L; Thackray, Varykina G | P42ES010337 | Endocrinology (2012 Apr) | 22294749 | 2012 |
FXR and PXR: potential therapeutic targets in cholestasis. | Jonker, Johan W; Liddle, Christopher; Downes, Michael | P42ES010337 | J Steroid Biochem Mol Biol (2012 Jul) | 21801835 | 2012 |
Hepatic expression of HCV RNA-dependent RNA polymerase triggers innate immune signaling and cytokine ... | Yu, Guann-Yi; He, Guobin; Li, Chia-Yang; Tang, Martin; Grivennikov, Sergei; Tsai, Wan-Ting; Wu ... | P42ES010337 | Mol Cell (2012 Oct 26) | 22959272 | 2012 |
Inherited genetic variants in autism-related CNTNAP2 show perturbed trafficking and ATF6 activation. | Falivelli, Giulia; De Jaco, Antonella; Favaloro, Flores Lietta; Kim, Hyuck; Wilson, Jennifer; D ... | P42ES010337 | Hum Mol Genet (2012 Nov 1) | 22872700 | 2012 |
Iron(III)-doped, silica nanoshells: a biodegradable form of silica. | Pohaku Mitchell, Kristina K; Liberman, Alexander; Kummel, Andrew C; Trogler, William C | P42ES010337 | J Am Chem Soc (2012 Aug 29) | 22871140 | 2012 |
Liver epithelial cells proliferate under hypoxia and protect the liver from ischemic injury via expr ... | Abe, Yuki; Uchinami, Hiroshi; Kudoh, Kazuhiro; Nakagawa, Yasuhiko; Ise, Norihito; Watanabe, Go ... | P42ES010337 | Surgery (2012 Nov) | 22575885 | 2012 |
Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3. | Lee, Jun Hee; Budanov, Andrei V; Talukdar, Saswata; Park, Eek Joong; Park, Hae Li; Park, Hwan- ... | P42ES010337 | Cell Metab (2012 Sep 05) | 22958918 | 2012 |
Obesity, inflammation, and liver cancer. | Sun, Beicheng; Karin, Michael | P42ES010337 | J Hepatol (2012 Mar) | 22120206 | 2012 |
Pregnane-x-receptor controls hepatic glucuronidation during pregnancy and neonatal development in hu ... | Chen, Shujuan; Yueh, Mei-Fei; Evans, Ronald M; Tukey, Robert H | P42ES010337 | Hepatology (2012 Aug) | 22371261 | 2012 |
Prenatal exposure to low levels of androgen accelerates female puberty onset and reproductive senesc ... | Witham, Emily A; Meadows, Jason D; Shojaei, Shadi; Kauffman, Alexander S; Mellon, Pamela L | P42ES010337 | Endocrinology (2012 Sep) | 22778229 | 2012 |
Processing of cholinesterase-like α/β-hydrolase fold proteins: alterations associated with congenita ... | De Jaco, Antonella; Comoletti, Davide; Dubi, Noga; Camp, Shelley; Taylor, Palmer | P42ES010337 | Protein Pept Lett (2012 Feb) | 21933121 | 2012 |
Reduced expression of UGT1A1 in intestines of humanized UGT1 mice via inactivation of NF-κB leads to ... | Fujiwara, Ryoichi; Chen, Shujuan; Karin, Michael; Tukey, Robert H | P42ES010337 | Gastroenterology (2012 Jan) | 21983082 | 2012 |
Stress levels of glucocorticoids inhibit LHβ-subunit gene expression in gonadotrope cells. | Breen, Kellie M; Thackray, Varykina G; Hsu, Tracy; Mak-McCully, Rachel A; Coss, Djurdjica; Mell ... | P42ES010337 | Mol Endocrinol (2012 Oct) | 22851703 | 2012 |
Targeting the pregnane X receptor in liver injury. | Li, Tao; Yu, Ruth T; Atkins, Annette R; Downes, Michael; Tukey, Robert H; Evans, Ronald M | P42ES010337 | Expert Opin Ther Targets (2012 Nov) | 22913318 | 2012 |
Triclocarban mediates induction of xenobiotic metabolism through activation of the constitutive andr ... | Yueh, Mei-Fei; Li, Tao; Evans, Ronald M; Hammock, Bruce; Tukey, Robert H | P42ES004699, P42ES010337 | PLoS One (2012) | 22761658 | 2012 |
Analysis of in situ manganese(II) oxidation in the Columbia River and offshore plume: linking Aurant ... | Anderson, C R; Davis, R E; Bandolin, N S; Baptista, A M; Tebo, B M | P42ES010337 | Environ Microbiol (2011 Jun) | 21418498 | 2011 |
AtHKT1;1 mediates nernstian sodium channel transport properties in Arabidopsis root stelar cells. | Xue, Shaowu; Yao, Xuan; Luo, Wei; Jha, Deepa; Tester, Mark; Horie, Tomoaki; Schroeder, Julian ... | P42ES010337 | PLoS One (2011) | 21931830 | 2011 |
Culturable Rhodobacter and Shewanella species are abundant in estuarine turbidity maxima of the Colu ... | Bräuer, S L; Adams, C; Kranzler, K; Murphy, D; Xu, M; Zuber, P; Simon, H M; Baptista, A M; T ... | P42ES010337 | Environ Microbiol (2011 Mar) | 20977571 | 2011 |
Distinct localization of collagen Q and PRiMA forms of acetylcholinesterase at the neuromuscular jun ... | Bernard, Véronique; Girard, Emmanuelle; Hrabovska, Anna; Camp, Shelley; Taylor, Palmer; Plaud, ... | P42ES010337 | Mol Cell Neurosci (2011 Jan) | 20883790 | 2011 |
Ectopic expression of CD74 in Ikkβ-deleted mouse hepatocytes. | Koch, Katherine S; Leffert, Hyam L | P42ES010337 | Acta Histochem (2011 Jul) | 20569972 | 2011 |
Evolution of abscisic acid synthesis and signaling mechanisms. | Hauser, Felix; Waadt, Rainer; Schroeder, Julian I | P42ES010337 | Curr Biol (2011 May 10) | 21549957 | 2011 |
Extrahepatic cancer suppresses nuclear receptor-regulated drug metabolism. | Kacevska, Marina; Downes, Michael R; Sharma, Rohini; Evans, Ronald M; Clarke, Stephen J; Liddle ... | P42ES010337 | Clin Cancer Res (2011 May 15) | 21498392 | 2011 |
Fibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liver. | Österreicher, Christoph H; Penz-Österreicher, Melitta; Grivennikov, Sergei I; Guma, Monica; Kolt ... | P42ES010337 | Proc Natl Acad Sci U S A (2011 Jan 04) | 21173249 | 2011 |
GWAS of butyrylcholinesterase activity identifies four novel loci, independent effects within BCHE a ... | Benyamin, Beben; Middelberg, Rita P; Lind, Penelope A; Valle, Anne M; Gordon, Scott; Nyholt, D ... | P42ES010337 | Hum Mol Genet (2011 Nov 15) | 21862451 | 2011 |
Hypothalamic dysregulation and infertility in mice lacking the homeodomain protein Six6. | Larder, Rachel; Clark, Daniel D; Miller, Nichol L G; Mellon, Pamela L | P42ES010337 | J Neurosci (2011 Jan 12) | 21228153 | 2011 |
Inhibition of human UGT2B7 gene expression in transgenic mice by the constitutive androstane recepto ... | Yueh, M F; Mellon, P L; Tukey, R H | P42ES010337 | Mol Pharmacol (2011 Jun) | 21415305 | 2011 |
K+ transport by the OsHKT2;4 transporter from rice with atypical Na+ transport properties and compet ... | Horie, Tomoaki; Brodsky, Dennis E; Costa, Alex; Kaneko, Toshiyuki; Lo Schiavo, Fiorella; Katsuh ... | P42ES010337 | Plant Physiol (2011 Jul) | 21610181 | 2011 |
Long-distance transport, vacuolar sequestration, tolerance, and transcriptional responses induced by ... | Mendoza-Cózatl, David G; Jobe, Timothy O; Hauser, Felix; Schroeder, Julian I | P42ES010337 | Curr Opin Plant Biol (2011 Oct) | 21820943 | 2011 |
Naturally occurring variations in the human cholinesterase genes: heritability and association with ... | Valle, Anne M; Radic, Zoran; Rana, Brinda K; Mahboubi, Vafa; Wessel, Jennifer; Shih, Pei-an Be ... | P42ES010337 | J Pharmacol Exp Ther (2011 Jul) | 21493754 | 2011 |
Quantitative transcriptomic analysis of abscisic acid-induced and reactive oxygen species-dependent ... | Bohmer, Maik; Schroeder, Julian I | P42ES010337 | Plant J (2011 Jul) | 21426425 | 2011 |
Roles of intracellular hydrogen peroxide accumulation in abscisic acid signaling in Arabidopsis guar ... | Jannat, Rayhanur; Uraji, Misugi; Morofuji, Miho; Islam, Mohammad Muzahidul; Bloom, Rachel E; Na ... | P42ES010337 | J Plant Physiol (2011 Nov 01) | 21665322 | 2011 |
Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation. | Holzer, Ryan G; Park, Eek-Joong; Li, Ning; Tran, Helen; Chen, Monica; Choi, Crystal; Solinas, ... | P42ES010337 | Cell (2011 Sep 30) | 21962514 | 2011 |
The crystal structure of the α-neurexin-1 extracellular region reveals a hinge point for mediating s ... | Miller, Meghan T; Mileni, Mauro; Comoletti, Davide; Stevens, Raymond C; Harel, Michal; Taylor, ... | P42ES010337 | Structure (2011 Jun 08) | 21620717 | 2011 |
A humanized UGT1 mouse model expressing the UGT1A1*28 allele for assessing drug clearance by UGT1A1- ... | Cai, Hongliang; Nguyen, Nghia; Peterkin, Vincent; Yang, Young-Sun; Hotz, Kathy; La Placa, Deir ... | P42ES010337 | Drug Metab Dispos (2010 May) | 20124398 | 2010 |
Arsenic tolerance in Arabidopsis is mediated by two ABCC-type phytochelatin transporters. | Song, Won-Yong; Park, Jiyoung; Mendoza-Cozatl, David G; Suter-Grotemeyer, Marianne; Shim, Dongh ... | P42ES010337 | Proc Natl Acad Sci U S A (2010 Dec 7) | 21078981 | 2010 |
Cis and trans actions of the cholinesterase-like domain within the thyroglobulin dimer. | Wang, Xiaofan; Lee, Jaemin; Di Jeso, Bruno; Treglia, A Sonia; Comoletti, Davide; Dubi, Noga; T ... | P42ES010337 | J Biol Chem (2010 Jun 04) | 20353937 | 2010 |
Conformational remodeling of femtomolar inhibitor-acetylcholinesterase complexes in the crystalline ... | Bourne, Yves; Radić, Zoran; Taylor, Palmer; Marchot, Pascale | P42ES010337 | J Am Chem Soc (2010 Dec 29) | 21090615 | 2010 |
Contributions of selective knockout studies to understanding cholinesterase disposition and function ... | Camp, Shelley; Zhang, Limin; Krejci, Eric; Dobbertin, Alexandre; Bernard, Veronique; Girard, E ... | P42ES010337 | Chem Biol Interact (2010 Sep 6) | 20153304 | 2010 |
Developmental hyperbilirubinemia and CNS toxicity in mice humanized with the UDP glucuronosyltransfe ... | Fujiwara, Ryoichi; Nguyen, Nghia; Chen, Shujuan; Tukey, Robert H | P42ES010337 | Proc Natl Acad Sci U S A (2010 Mar 16) | 20194756 | 2010 |
Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF e ... | Park, Eek Joong; Lee, Jun Hee; Yu, Guann-Yi; He, Guobin; Ali, Syed Raza; Holzer, Ryan G; Oster ... | P42ES010337 | Cell (2010 Jan 22) | 20141834 | 2010 |
Differential sodium and potassium transport selectivities of the rice OsHKT2;1 and OsHKT2;2 transpor ... | Yao, Xuan; Horie, Tomoaki; Xue, Shaowu; Leung, Ho-Yin; Katsuhara, Maki; Brodsky, Dennis E; Wu, ... | P42ES010337 | Plant Physiol (2010 Jan) | 19889878 | 2010 |
From Split to Sibenik: the tortuous pathway in the cholinesterase field. | Taylor, Palmer | P42ES010337 | Chem Biol Interact (2010 Sep 6) | 20493179 | 2010 |
Guard cell signal transduction network: advances in understanding abscisic acid, CO2, and Ca2+ signa ... | Kim, Tae-Houn; Böhmer, Maik; Hu, Honghong; Nishimura, Noriyuki; Schroeder, Julian I | P42ES010337 | Annu Rev Plant Biol (2010) | 20192751 | 2010 |
H2O2 in plant peroxisomes: an in vivo analysis uncovers a Ca(2+)-dependent scavenging system. | Costa, Alex; Drago, Ilaria; Behera, Smrutisanjita; Zottini, Michela; Pizzo, Paola; Schroeder, ... | P42ES010337 | Plant J (2010 Jun 01) | 20230493 | 2010 |
Hepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress ... | He, Guobin; Yu, Guann-Yi; Temkin, Vladislav; Ogata, Hisanobu; Kuntzen, Christian; Sakurai, Tos ... | P42ES010337 | Cancer Cell (2010 Mar 16) | 20227042 | 2010 |
High-affinity K(+) transport in Arabidopsis: AtHAK5 and AKT1 are vital for seedling establishment an ... | Pyo, Young Jae; Gierth, Markus; Schroeder, Julian I; Cho, Myeon Haeng | P42ES010337 | Plant Physiol (2010 Jun) | 20413648 | 2010 |
Hypothesis: Targeted Ikkβ deletion upregulates MIF signaling responsiveness and MHC class II express ... | Koch, Katherine S; Leffert, Hyam L | P42ES010337 | Hepat Med (2010 Mar) | 23997575 | 2010 |
Metabolism: Tick, tock, a beta-cell clock. | Lamia, Katja A; Evans, Ronald M | P42ES010337 | Nature (2010 Jul 29) | 20671699 | 2010 |
Mitochondrial rejuvenation after induced pluripotency. | Suhr, Steven T; Chang, Eun Ah; Tjong, Jonathan; Alcasid, Nathan; Perkins, Guy A; Goissis, Marc ... | P42ES010337 | PLoS One (2010 Nov 23) | 21124794 | 2010 |
Neuroligin trafficking deficiencies arising from mutations in the alpha/beta-hydrolase fold protein ... | De Jaco, Antonella; Lin, Michael Z; Dubi, Noga; Comoletti, Davide; Miller, Meghan T; Camp, She ... | P42ES010337 | J Biol Chem (2010 Sep 10) | 20615874 | 2010 |
Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies. | Lee, Jun Hee; Budanov, Andrei V; Park, Eek Joong; Birse, Ryan; Kim, Teddy E; Perkins, Guy A; O ... | P42ES010337 | Science (2010 Mar 05) | 20203043 | 2010 |
Sestrins at the crossroad between stress and aging. | Lee, Jun Hee; Bodmer, Rolf; Bier, Ethan; Karin, Michael | P42ES010337 | Aging (Albany NY) (2010 Jun) | 20606249 | 2010 |
Stressin' Sestrins take an aging fight. | Budanov, Andrei V; Lee, Jun Hee; Karin, Michael | P42ES010337 | EMBO Mol Med (2010 Oct) | 20878915 | 2010 |
Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR ... | Bourne, Yves; Radic, Zoran; Aráoz, Rómulo; Talley, Todd T; Benoit, Evelyne; Servent, Denis; Ta ... | P42ES010337 | Proc Natl Acad Sci U S A (2010 Mar 30) | 20224036 | 2010 |
Structural insights into the exquisite selectivity of neurexin/neuroligin synaptic interactions. | Leone, Philippe; Comoletti, Davide; Ferracci, Géraldine; Conrod, Sandrine; Garcia, Simon U; Tay ... | P42ES010337 | EMBO J (2010 Jul 21) | 20543817 | 2010 |
The genome of the Gram-positive metal- and sulfate-reducing bacterium Desulfotomaculum reducens stra ... | Junier, Pilar; Junier, Thomas; Podell, Sheila; Sims, David R; Detter, John C; Lykidis, Athanas ... | P42ES010337 | Environ Microbiol (2010 Oct) | 20482743 | 2010 |
The macromolecular architecture of extracellular domain of alphaNRXN1: domain organization, flexibil ... | Comoletti, Davide; Miller, Meghan T; Jeffries, Cy M; Wilson, Jennifer; Demeler, Borries; Taylor ... | P42ES010337 | Structure (2010 Aug 11) | 20696403 | 2010 |
Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation. | Takahashi, Hiroyuki; Ogata, Hisanobu; Nishigaki, Reiko; Broide, David H; Karin, Michael | P42ES010337 | Cancer Cell (2010 Jan 19) | 20129250 | 2010 |
Tonoplast-localized Abc2 transporter mediates phytochelatin accumulation in vacuoles and confers cad ... | Mendoza-Cózatl, David G; Zhai, Zhiyang; Jobe, Timothy O; Akmakjian, Garo Z; Song, Won-Yong; Lim ... | P42ES010337 | J Biol Chem (2010 Dec 24) | 20937798 | 2010 |
A lymphotoxin-driven pathway to hepatocellular carcinoma. | Haybaeck, Johannes; Zeller, Nicolas; Wolf, Monika Julia; Weber, Achim; Wagner, Ulrich; Kurrer, ... | P42ES010337 | Cancer Cell (2009 Oct 06) | 19800575 | 2009 |
Angiotensin-converting-enzyme 2 inhibits liver fibrosis in mice. | Osterreicher, Christoph H; Taura, Kojiro; De Minicis, Samuele; Seki, Ekihiro; Penz-Osterreicher, ... | P42ES010337 | Hepatology (2009 Sep) | 19650157 | 2009 |
ARS5 is a component of the 26S proteasome complex, and negatively regulates thiol biosynthesis and a ... | Sung, Dong-Yul; Kim, Tae-Houn; Komives, Elizabeth A; Mendoza-Cózatl, David G; Schroeder, Julian ... | P42ES010337 | Plant J (2009 Sep) | 19453443 | 2009 |
Aurantimonas manganoxydans, sp. nov. and Aurantimonas litoralis, sp. nov.: Mn(II) oxidizing represen ... | Anderson, C R; Dick, G J; Chu, M-L; Cho, J-C; Davis, R E; Bräuer, S L; Tebo, B M | P42ES010337 | Geomicrobiol J (2009 Apr 1) | 19768133 | 2009 |
Centaurin-like protein Cnt5 contributes to arsenic and cadmium resistance in fission yeast. | Vashisht, Ajay Amar; Kennedy, Patrick Joseph; Russell, Paul | P42ES010337 | FEMS Yeast Res (2009 Mar) | 19076239 | 2009 |
Chapter 2 Correlated light and electron microscopy/electron tomography of mitochondria in situ. | Perkins, Guy A; Sun, Mei G; Frey, Terrence G | P42ES010337 | Methods Enzymol (2009) | 19348881 | 2009 |
Dynamics of mitochondrial structure during apoptosis and the enigma of Opa1. | Yamaguchi, Ryuji; Perkins, Guy | P42ES010337 | Biochim Biophys Acta (2009 Aug) | 19245786 | 2009 |
HKT transporter-mediated salinity resistance mechanisms in Arabidopsis and monocot crop plants. | Horie, Tomoaki; Hauser, Felix; Schroeder, Julian I | P42ES010337 | Trends Plant Sci (2009 Dec) | 19783197 | 2009 |
Influence of differential expression of acetylcholinesterase in brain and muscle on respiration. | Boudinot, Eliane; Bernard, Véronique; Camp, Shelley; Taylor, Palmer; Champagnat, Jean; Krejci, ... | P42ES010337 | Respir Physiol Neurobiol (2009 Jan 01) | 18977317 | 2009 |
Mn(II) oxidation is catalyzed by heme peroxidases in "Aurantimonas manganoxydans" strain SI85-9A1 an ... | Anderson, C R; Johnson, H A; Caputo, N; Davis, R E; Torpey, J W; Tebo, B M | P42ES010337 | Appl Environ Microbiol (2009 Jun) | 19411418 | 2009 |
Necdin, a Prader-Willi syndrome candidate gene, regulates gonadotropin-releasing hormone neurons dur ... | Miller, Nichol L G; Wevrick, Rachel; Mellon, Pamela L | P42ES010337 | Hum Mol Genet (2009 Jan 15) | 18930956 | 2009 |
New insights into mitochondrial structure during cell death. | Perkins, Guy; Bossy-Wetzel, Ella; Ellisman, Mark H | P42ES010337 | Exp Neurol (2009 Aug) | 19464290 | 2009 |
Plant ion channels: gene families, physiology, and functional genomics analyses. | Ward, John M; Mäser, Pascal; Schroeder, Julian I | P42ES010337 | Annu Rev Physiol (2009) | 18842100 | 2009 |
Structural mechanism of abscisic acid binding and signaling by dimeric PYR1. | Nishimura, Noriyuki; Hitomi, Kenichi; Arvai, Andrew S; Rambo, Robert P; Hitomi, Chiharu; Cutler ... | P42ES010337 | Science (2009 Dec 04) | 19933100 | 2009 |
Studies on induction of lamotrigine metabolism in transgenic UGT1 mice. | Argikar, U A; Senekeo-Effenberger, K; Larson, E E; Tukey, R H; Remmel, R P | P42ES010337 | Xenobiotica (2009 Nov) | 19845433 | 2009 |
Targeted deletion of hepatocyte Ikkbeta confers growth advantages. | Koch, Katherine S; Maeda, Shin; He, Guobin; Karin, Michael; Leffert, Hyam L | P42ES010337 | Biochem Biophys Res Commun (2009 Mar 06) | 19171122 | 2009 |
Targeting of acetylcholinesterase in neurons in vivo: a dual processing function for the proline-ric ... | Dobbertin, Alexandre; Hrabovska, Anna; Dembele, Korami; Camp, Shelley; Taylor, Palmer; Krejci, ... | P42ES010337 | J Neurosci (2009 Apr 8) | 19357277 | 2009 |
A genome-wide screen of genes involved in cadmium tolerance in Schizosaccharomyces pombe. | Kennedy, Patrick J; Vashisht, Ajay A; Hoe, Kwang-Lae; Kim, Dong-Uk; Park, Han-Oh; Hayles, Jacq ... | P42ES010337 | Toxicol Sci (2008 Nov) | 18684775 | 2008 |
Acetylcholinesterase expression in muscle is specifically controlled by a promoter-selective enhance ... | Camp, Shelley; De Jaco, Antonella; Zhang, Limin; Marquez, Michael; De la Torre, Brian; Taylor, ... | P42ES010337 | J Neurosci (2008 Mar 05) | 18322091 | 2008 |
An HPLC-ICP-MS technique for determination of cadmium-phytochelatins in genetically modified Arabido ... | Sadi, Baki B M; Vonderheide, Anne P; Gong, Ji-Ming; Schroeder, Julian I; Shann, Jodi R; Caruso, ... | P42ES010337 | J Chromatogr B Analyt Technol Biomed Life Sci (2008 Jan 1) | 18065298 | 2008 |
Characterization of the solution structure of a neuroligin/beta-neurexin complex. | Comoletti, Davide; Grishaev, Alexander; Whitten, Andrew E; Taylor, Palmer; Trewhella, Jill | P42ES010337 | Chem Biol Interact (2008 Sep 25) | 18550038 | 2008 |
Control of mRNA stability by SAPKs. | Rodríguez-Gabriel, Miguel A; Russell, Paul | P42ES010337 | Top Curr Genet (2008 Jan 01) | 21738496 | 2008 |
Direct identification of a bacterial manganese(II) oxidase, the multicopper oxidase MnxG, from spore ... | Dick, Gregory J; Torpey, Justin W; Beveridge, Terry J; Tebo, Bradley M | P42ES010337 | Appl Environ Microbiol (2008 Mar) | 18165363 | 2008 |
Disruption of the ugt1 locus in mice resembles human Crigler-Najjar type I disease. | Nguyen, Nghia; Bonzo, Jessica A; Chen, Shujuan; Chouinard, Sarah; Kelner, Michael J; Hardiman, ... | P42ES010337 | J Biol Chem (2008 Mar 21) | 18180294 | 2008 |
Expression of the novel wheat gene TM20 confers enhanced cadmium tolerance to bakers' yeast. | Kim, Yu-Young; Kim, Do-Young; Shim, Donghwan; Song, Won-Yong; Lee, Joohyun; Schroeder, Julian ... | P42ES010337 | J Biol Chem (2008 Jun 06) | 18411273 | 2008 |
Genomic insights into Mn(II) oxidation by the marine alphaproteobacterium Aurantimonas sp. strain SI ... | Dick, Gregory J; Podell, Sheila; Johnson, Hope A; Rivera-Espinoza, Yadira; Bernier-Latmani, Riz ... | P42ES010337 | Appl Environ Microbiol (2008 May) | 18344346 | 2008 |
Identification of high levels of phytochelatins, glutathione and cadmium in the phloem sap of Brassi ... | Mendoza-Cózatl, David G; Butko, Emerald; Springer, Franziska; Torpey, Justin W; Komives, Elizab ... | P42ES010337 | Plant J (2008 Apr) | 18208526 | 2008 |
In vitro studies indicate a quinone is involved in bacterial Mn(II) oxidation. | Johnson, Hope A; Tebo, Bradley M | P42ES010337 | Arch Microbiol (2008 Jan) | 17673976 | 2008 |
Liver cancer stem cells. | Sell, Stewart; Leffert, Hyam L | P42ES010337 | J Clin Oncol (2008 Jun 10) | 18539957 | 2008 |
Mitochondrial fragmentation in neurodegeneration. | Knott, Andrew B; Perkins, Guy; Schwarzenbacher, Robert; Bossy-Wetzel, Ella | P42ES010337 | Nat Rev Neurosci (2008 Jul) | 18568013 | 2008 |
NeuroD1 and Mash1 temporally regulate GnRH receptor gene expression in immortalized mouse gonadotrop ... | Cherrington, Brian D; Bailey, Janice S; Diaz, Alejandro L; Mellon, Pamela L | P42ES010337 | Mol Cell Endocrinol (2008 Nov 25) | 18760324 | 2008 |
NF-kappaB and cancer-identifying targets and mechanisms. | Naugler, Willscott E; Karin, Michael | P42ES010337 | Curr Opin Genet Dev (2008 Feb) | 18440219 | 2008 |
Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent ... | Yamaguchi, Ryuji; Lartigue, Lydia; Perkins, Guy; Scott, Ray T; Dixit, Amruta; Kushnareva, Yuli ... | P42ES010337 | Mol Cell (2008 Aug 22) | 18691924 | 2008 |
p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling. | Budanov, Andrei V; Karin, Michael | P42ES010337 | Cell (2008 Aug 08) | 18692468 | 2008 |
SLAC1 is required for plant guard cell S-type anion channel function in stomatal signalling. | Vahisalu, Triin; Kollist, Hannes; Wang, Yong-Fei; Nishimura, Noriyuki; Chan, Wai-Yin; Valerio, ... | P42ES010337 | Nature (2008 Mar 27) | 18305484 | 2008 |
Trafficking of cholinesterases and neuroligins mutant proteins. An association with autism. | De Jaco, Antonella; Comoletti, Davide; King, Charles C; Taylor, Palmer | P42ES010337 | Chem Biol Interact (2008 Sep 25) | 18555979 | 2008 |
Cr(III) is indirectly oxidized by the Mn(II)-oxidizing bacterium Bacillus sp. strain SG-1. | Murray, Karen J; Tebo, Bradley M | P42ES010337 | Environ Sci Technol (2007 Jan 15) | 17310717 | 2007 |
Expression of the human UGT1 locus in transgenic mice by 4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio ... | Senekeo-Effenberger, Kathy; Chen, Shujuan; Brace-Sinnokrak, Erin; Bonzo, Jessica A; Yueh, Mei-F ... | P42ES010337 | Drug Metab Dispos (2007 Mar) | 17151188 | 2007 |
Human CYP1A1GFP expression in transgenic mice serves as a biomarker for environmental toxicant expos ... | Operaña, Theresa N; Nguyen, Nghia; Chen, Shujuan; Beaton, Deirdre; Tukey, Robert H | P42ES010337 | Toxicol Sci (2007 Jan) | 17065433 | 2007 |
Identification of an arsenic tolerant double mutant with a thiol-mediated component and increased ar ... | Sung, Dong-Yul; Lee, David; Harris, Hugh; Raab, Andrea; Feldmann, Jörg; Meharg, Andrew; Kumabe ... | P42ES010337 | Plant J (2007 Mar) | 17335514 | 2007 |
Nrf2-Keap1 signaling pathway regulates human UGT1A1 expression in vitro and in transgenic UGT1 mice. | Yueh, Mei-Fei; Tukey, Robert H | P42ES010337 | J Biol Chem (2007 Mar 23) | 17259171 | 2007 |
PGC-1beta controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, ... | Sonoda, Junichiro; Mehl, Isaac R; Chong, Ling-Wa; Nofsinger, Russell R; Evans, Ronald M | P42ES010337 | Proc Natl Acad Sci U S A (2007 Mar 20) | 17360356 | 2007 |
Rice OsHKT2;1 transporter mediates large Na+ influx component into K+-starved roots for growth. | Horie, Tomoaki; Costa, Alex; Kim, Tae Houn; Han, Min Jung; Horie, Rie; Leung, Ho-Yin; Miyao, ... | P42ES010337 | EMBO J (2007 Jun 20) | 17541409 | 2007 |
Structural analysis of the synaptic protein neuroligin and its beta-neurexin complex: determinants f ... | Fabrichny, Igor P; Leone, Philippe; Sulzenbacher, Gerlind; Comoletti, Davide; Miller, Meghan T; ... | P42ES010337 | Neuron (2007 Dec 20) | 18093521 | 2007 |
Synaptic arrangement of the neuroligin/beta-neurexin complex revealed by X-ray and neutron scatterin ... | Comoletti, Davide; Grishaev, Alexander; Whitten, Andrew E; Tsigelny, Igor; Taylor, Palmer; Trew ... | P42ES010337 | Structure (2007 Jun) | 17562316 | 2007 |
The NIEHS Environmental Health Sciences Data Resource Portal: placing advanced technologies in servi ... | Pezzoli, Keith; Tukey, Robert; Sarabia, Hiram; Zaslavsky, Ilya; Miranda, Marie Lynn; Suk, Will ... | P42ES010337, P42ES010356 | Environ Health Perspect (2007 Apr) | 17450225 | 2007 |
The role of chrysin and the ah receptor in induction of the human UGT1A1 gene in vitro and in transg ... | Bonzo, Jessica A; Bélanger, Alain; Tukey, Robert H | P42ES010337 | Hepatology (2007 Feb) | 17256720 | 2007 |
Toxicity of Cr(lll) to Shewanella sp. strain MR-4 during Cr(VI) reduction. | Bencheikh-Latmani, Rizlan; Obraztsova, Anna; Mackey, Mason R; Ellisman, Mark H; Tebo, Bradley M | P42ES010337 | Environ Sci Technol (2007 Jan 01) | 17265950 | 2007 |
A mutation linked with autism reveals a common mechanism of endoplasmic reticulum retention for the ... | De Jaco, Antonella; Comoletti, Davide; Kovarik, Zrinka; Gaietta, Guido; Radic, Zoran; Lockridge ... | P42ES010337 | J Biol Chem (2006 Apr 07) | 16434405 | 2006 |
A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipog ... | Zhou, Jie; Zhai, Yonggong; Mu, Ying; Gong, Haibiao; Uppal, Hirdesh; Toma, David; Ren, Songron ... | P42ES010337 | J Biol Chem (2006 May 26) | 16556603 | 2006 |
An improved grafting technique for mature Arabidopsis plants demonstrates long-distance shoot-to-roo ... | Chen, Alice; Komives, Elizabeth A; Schroeder, Julian I | P42ES010337 | Plant Physiol (2006 May) | 16531489 | 2006 |
Behavior of mice with mutations in the conserved region deleted in velocardiofacial/DiGeorge syndrom ... | Long, Jeffrey M; LaPorte, Patricia; Merscher, Sandra; Funke, Birgit; Saint-Jore, Bruno; Puech, ... | P42ES010337 | Neurogenetics (2006 Nov) | 16900388 | 2006 |
Benefit of farnesoid X receptor inhibition in obstructive cholestasis. | Stedman, Catherine; Liddle, Christopher; Coulter, Sally; Sonoda, Junichiro; Alvarez, Jacqueline ... | P42ES010337 | Proc Natl Acad Sci U S A (2006 Jul 25) | 16844773 | 2006 |
Cip1 and Cip2 are novel RNA-recognition-motif proteins that counteract Csx1 function during oxidativ ... | Martín, Victoria; Rodríguez-Gabriel, Miguel A; McDonald, W Hayes; Watt, Stephen; Yates 3rd, Joh ... | P42ES010337 | Mol Biol Cell (2006 Mar) | 16407405 | 2006 |
Gene selection, alternative splicing, and post-translational processing regulate neuroligin selectiv ... | Comoletti, Davide; Flynn, Robyn E; Boucard, Antony A; Demeler, Borries; Schirf, Virgil; Shi, J ... | P42ES010337 | Biochemistry (2006 Oct 24) | 17042500 | 2006 |
Immune-privileged embryonic Swiss mouse STO and STO cell-derived progenitor cells: major histocompat ... | Koch, Katherine S; Son, Kyung-Hwa; Maehr, Rene; Pellicciotta, Illenia; Ploegh, Hidde L; Zanetti ... | P42ES010337 | Immunology (2006 Sep) | 16836618 | 2006 |
International Union of Pharmacology. LX. Retinoic acid receptors. | Germain, Pierre; Chambon, Pierre; Eichele, Gregor; Evans, Ronald M; Lazar, Mitchell A; Leid, M ... | P42ES010337 | Pharmacol Rev (2006 Dec) | 17132850 | 2006 |
International Union of Pharmacology. LXIII. Retinoid X receptors. | Germain, Pierre; Chambon, Pierre; Eichele, Gregor; Evans, Ronald M; Lazar, Mitchell A; Leid, M ... | P42ES010337 | Pharmacol Rev (2006 Dec) | 17132853 | 2006 |
Ligand-induced conformational changes in the acetylcholine-binding protein analyzed by hydrogen-deut ... | Shi, Jianxin; Koeppe, Julia R; Komives, Elizabeth A; Taylor, Palmer | P42ES010337 | J Biol Chem (2006 Apr 28) | 16484218 | 2006 |
Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N ... | Sakurai, Toshiharu; Maeda, Shin; Chang, Lufen; Karin, Michael | P42ES010337 | Proc Natl Acad Sci U S A (2006 Jul 11) | 16807293 | 2006 |
Manganese(II)-oxidizing Bacillus spores in Guaymas Basin hydrothermal sediments and plumes. | Dick, Gregory J; Lee, Yifan E; Tebo, Bradley M | P42ES010337 | Appl Environ Microbiol (2006 May) | 16672456 | 2006 |
Upf1, an RNA helicase required for nonsense-mediated mRNA decay, modulates the transcriptional respo ... | Rodríguez-Gabriel, Miguel A; Watt, Stephen; Bähler, Jürg; Russell, Paul | P42ES010337 | Mol Cell Biol (2006 Sep) | 16914721 | 2006 |
Arsenite inhibition of CYP1A1 induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin is independent of cel ... | Bonzo, Jessica A; Chen, Shujuan; Galijatovic, Alema; Tukey, Robert H | P42ES010337 | Mol Pharmacol (2005 Apr) | 15630080 | 2005 |
Distinct signaling pathways respond to arsenite and reactive oxygen species in Schizosaccharomyces p ... | Rodríguez-Gabriel, Miguel A; Russell, Paul | P42ES010337 | Eukaryot Cell (2005 Aug) | 16087744 | 2005 |
Embryonic mouse STO cell-derived xenografts express hepatocytic functions in the livers of nonimmuno ... | Zhang, Mingjun; Joseph, Brigid; Gupta, Sanjeev; Guest, I; Xu, Meng; Sell, Stewart; Son, Kyung ... | P42ES010337 | Stem Cells (2005 Feb) | 15671142 | 2005 |
Enhanced salt tolerance mediated by AtHKT1 transporter-induced Na unloading from xylem vessels to xy ... | Sunarpi; Horie, Tomoaki; Motoda, Jo; Kubo, Masahiro; Yang, Hua; Yoda, Kinya; Horie, Rie; Chan, ... | P42ES010337 | Plant J (2005 Dec) | 16359386 | 2005 |
ERK kinase inhibition stabilizes the aryl hydrocarbon receptor: implications for transcriptional act ... | Chen, Shujuan; Operaña, Theresa; Bonzo, Jessica; Nguyen, Nghia; Tukey, Robert H | P42ES010337 | J Biol Chem (2005 Feb 11) | 15572374 | 2005 |
Geomicrobiology of manganese(II) oxidation. | Tebo, Bradley M; Johnson, Hope A; McCarthy, James K; Templeton, Alexis S | P42ES010337 | Trends Microbiol (2005 Sep) | 16054815 | 2005 |
Global transcriptional profiling of Shewanella oneidensis MR-1 during Cr(VI) and U(VI) reduction. | Bencheikh-Latmani, Rizlan; Williams, Sarah Middleton; Haucke, Lisa; Criddle, Craig S; Wu, Liyou ... | P42ES010337 | Appl Environ Microbiol (2005 Nov) | 16269787 | 2005 |
IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemica ... | Maeda, Shin; Kamata, Hideaki; Luo, Jun-Li; Leffert, Hyam; Karin, Michael | P42ES010337 | Cell (2005 Jul 01) | 15989949 | 2005 |
Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MA ... | Kamata, Hideaki; Honda, Shi-Ichi; Maeda, Shin; Chang, Lufen; Hirata, Hajime; Karin, Michael | P42ES010337 | Cell (2005 Mar 11) | 15766528 | 2005 |
The innate immune response under the control of the LXR pathway. | Valledor, Annabel F | P42ES010337 | Immunobiology (2005) | 16164019 | 2005 |
The role of protein kinase C in regulation of TCDD-mediated CYP1A1 gene expression. | Machemer, Daniel E W; Tukey, Robert H | P42ES010337 | Toxicol Sci (2005 Sep) | 15947024 | 2005 |
Tissue-specific, inducible, and hormonal control of the human UDP-glucuronosyltransferase-1 (UGT1) l ... | Chen, Shujuan; Beaton, Deirdre; Nguyen, Nghia; Senekeo-Effenberger, Kathy; Brace-Sinnokrak, Eri ... | P42ES010337 | J Biol Chem (2005 Nov 11) | 16155002 | 2005 |
Activation of liver X receptors and retinoid X receptors prevents bacterial-induced macrophage apopt ... | Valledor, Annabel F; Hsu, Li-Chung; Ogawa, Sumito; Sawka-Verhelle, Dominique; Karin, Michael; G ... | P42ES010337 | Proc Natl Acad Sci U S A (2004 Dec 21) | 15601766 | 2004 |
Balanol analogues probe specificity determinants and the conformational malleability of the cyclic 3 ... | Akamine, Pearl; Madhusudan; Brunton, Laurence L; Ou, Horng D; Canaves, Jaume M; Xuong, Nguyen-h ... | P42ES010337 | Biochemistry (2004 Jan 13) | 14705934 | 2004 |
Expanded characterization of the social interaction abnormalities in mice lacking Dvl1. | Long, J M; LaPorte, P; Paylor, R; Wynshaw-Boris, A | P42ES010337 | Genes Brain Behav (2004 Feb) | 14960015 | 2004 |
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. | Greten, Florian R; Eckmann, Lars; Greten, Tim F; Park, Jin Mo; Li, Zhi-Wei; Egan, Laurence J; ... | P42ES010337 | Cell (2004 Aug 06) | 15294155 | 2004 |
Imaging dynamic redox changes in mammalian cells with green fluorescent protein indicators. | Dooley, Colette T; Dore, Timothy M; Hanson, George T; Jackson, W Coyt; Remington, S James; Tsie ... | P42ES010337 | J Biol Chem (2004 May 21) | 14985369 | 2004 |
Overexpression of phytochelatin synthase in Arabidopsis leads to enhanced arsenic tolerance and cadm ... | Li, Yujing; Dhankher, Om Parkash; Carreira, Laura; Lee, David; Chen, Alice; Schroeder, Julian ... | P42ES010337 | Plant Cell Physiol (2004 Dec) | 15653797 | 2004 |
Repression of IFN-gamma expression by peroxisome proliferator-activated receptor gamma. | Cunard, Robyn; Eto, Yoko; Muljadi, Julie T; Glass, Christopher K; Kelly, Carolyn J; Ricote, Me ... | P42ES010337 | J Immunol (2004 Jun 15) | 15187132 | 2004 |
Structural characterization of recombinant soluble rat neuroligin 1: mapping of secondary structure ... | Hoffman, Ross C; Jennings, Lori L; Tsigelny, Igor; Comoletti, Davide; Flynn, Robyn E; Sudhof, ... | P42ES010337 | Biochemistry (2004 Feb 17) | 14769026 | 2004 |
Structural organization of the murine microsomal glutathione S-transferase gene (MGST1) from the 129 ... | Kelner, Michael J; Bagnell, Richard D; Morgenstern, Ralf | P42ES010337 | Biochim Biophys Acta (2004 May 25) | 15157743 | 2004 |
The Arg451Cys-neuroligin-3 mutation associated with autism reveals a defect in protein processing. | Comoletti, Davide; De Jaco, Antonella; Jennings, Lori L; Flynn, Robyn E; Gaietta, Guido; Tsigel ... | P42ES010337 | J Neurosci (2004 May 19) | 15152050 | 2004 |
The human CYP1A1 gene is regulated in a developmental and tissue-specific fashion in transgenic mice ... | Galijatovic, Alema; Beaton, Deirdre; Nguyen, Nghia; Chen, Shujuan; Bonzo, Jessica; Johnson, Ra ... | P42ES010337 | J Biol Chem (2004 Jun 04) | 15037607 | 2004 |
The two NF-kappaB activation pathways and their role in innate and adaptive immunity. | Bonizzi, Giuseppina; Karin, Michael | P42ES010337 | Trends Immunol (2004 Jun) | 15145317 | 2004 |
ars1, an Arabidopsis mutant exhibiting increased tolerance to arsenate and increased phosphate uptak ... | Lee, David A; Chen, Alice; Schroeder, Julian I | P42ES010337 | Plant J (2003 Sep) | 12940956 | 2003 |
Basal expression of the human MAPEG members microsomal glutathione transferase 1 and prostaglandin E ... | Ekström, Lena; Lyrenäs, Louise; Jakobsson, Per-Johan; Morgenstern, Ralf; Kelner, Michael J | P42ES010337 | Biochim Biophys Acta (2003 Jun 19) | 12818425 | 2003 |
Bcl-xL overexpression blocks bax-mediated mitochondrial contact site formation and apoptosis in rod ... | He, Lihua; Perkins, Guy A; Poblenz, Ann T; Harris, Jeffrey B; Hung, Michael; Ellisman, Mark H; ... | P42ES010337 | Proc Natl Acad Sci U S A (2003 Feb 4) | 12540825 | 2003 |
Cometabolism of Cr(VI) by Shewanella oneidensis MR-1 produces cell-associated reduced chromium and i ... | Middleton, Sarah S; Latmani, Rizlan Bencheikh; Mackey, Mason R; Ellisman, Mark H; Tebo, Bradley ... | P42ES004911, P42ES010337 | Biotechnol Bioeng (2003 Sep 20) | 12889027 | 2003 |
Direct analysis of the kinetic profiles of organophosphate-acetylcholinesterase adducts by MALDI-TOF ... | Jennings, Lori L; Malecki, Michael; Komives, Elizabeth A; Taylor, Palmer | P42ES010337 | Biochemistry (2003 Sep 23) | 12974645 | 2003 |
Hepatic progenitor cell lines from allyl alcohol-treated adult rats are derived from gamma-irradiate ... | Zhang, Mingjun; Sell, Stewart; Leffert, Hyam L | P42ES010337 | Stem Cells (2003) | 12832698 | 2003 |
IKK beta is required for peripheral B cell survival and proliferation. | Li, Zhi-Wei; Omori, Sidne A; Labuda, Tord; Karin, Michael; Rickert, Robert C | P42ES010337 | J Immunol (2003 May 01) | 12707341 | 2003 |
IKKbeta is required for prevention of apoptosis mediated by cell-bound but not by circulating TNFalp ... | Maeda, Shin; Chang, Lufen; Li, Zhi-Wei; Luo, Jun-Li; Leffert, Hyam; Karin, Michael | P42ES010337 | Immunity (2003 Nov) | 14614859 | 2003 |
Involvement of the xenobiotic response element (XRE) in Ah receptor-mediated induction of human UDP- ... | Yueh, Mei-Fei; Huang, Yue-Hua; Hiller, Anita; Chen, Shujuan; Nguyen, Nghia; Tukey, Robert H | P42ES010337 | J Biol Chem (2003 Apr 25) | 12566446 | 2003 |
Localization and functional characterization of metal-binding sites in phytochelatin synthases. | Maier, Thomas; Yu, Chao; Küllertz, Gerhard; Clemens, Stephan | P42ES010337 | Planta (2003 Dec) | 12905027 | 2003 |
Long-distance root-to-shoot transport of phytochelatins and cadmium in Arabidopsis. | Gong, Ji-Ming; Lee, David A; Schroeder, Julian I | P42ES010337 | Proc Natl Acad Sci U S A (2003 Aug 19) | 12909714 | 2003 |
Nanosecond dynamics of the mouse acetylcholinesterase cys69-cys96 omega loop. | Shi, Jianxin; Tai, Kaihsu; McCammon, J Andrew; Taylor, Palmer; Johnson, David A | P42ES010337 | J Biol Chem (2003 Aug 15) | 12759360 | 2003 |
PPARgamma and PPARdelta negatively regulate specific subsets of lipopolysaccharide and IFN-gamma tar ... | Welch, John S; Ricote, Mercedes; Akiyama, Taro E; Gonzalez, Frank J; Glass, Christopher K | P42ES010337 | Proc Natl Acad Sci U S A (2003 May 27) | 12740443 | 2003 |
RNA-binding protein Csx1 mediates global control of gene expression in response to oxidative stress. | Rodríguez-Gabriel, Miguel A; Burns, Gavin; McDonald, W Hayes; Martín, Victoria; Yates 3rd, John ... | P42ES010337 | EMBO J (2003 Dec 01) | 14633985 | 2003 |
The role of the Ah receptor and p38 in benzo[a]pyrene-7,8-dihydrodiol and benzo[a]pyrene-7,8-dihydro ... | Chen, Shujuan; Nguyen, Nghia; Tamura, Kumiko; Karin, Michael; Tukey, Robert H | P42ES010337 | J Biol Chem (2003 May 23) | 12637498 | 2003 |
Altered shoot/root Na+ distribution and bifurcating salt sensitivity in Arabidopsis by genetic disru ... | Mäser, Pascal; Eckelman, Brendan; Vaidyanathan, Rama; Horie, Tomoaki; Fairbairn, David J; Kubo, ... | P42ES010337 | FEBS Lett (2002 Nov 06) | 12417304 | 2002 |
Derivation, characterization, and phenotypic variation of hepatic progenitor cell lines isolated fro ... | Yin, Li; Sun, Mingzeng; Ilic, Zoran; Leffert, Hyam L; Sell, Stewart | P42ES010337 | Hepatology (2002 Feb) | 11826404 | 2002 |
Doublecortin is required in mice for lamination of the hippocampus but not the neocortex. | Corbo, Joseph C; Deuel, Thomas A; Long, Jeffrey M; LaPorte, Patricia; Tsai, Elena; Wynshaw-Bori ... | P42ES010337 | J Neurosci (2002 Sep 01) | 12196578 | 2002 |
Enzymatic manganese(II) oxidation by metabolically dormant spores of diverse Bacillus species. | Francis, Chris A; Tebo, Bradley M | P42ES010337 | Appl Environ Microbiol (2002 Feb) | 11823231 | 2002 |
Glycine residues in potassium channel-like selectivity filters determine potassium selectivity in fo ... | Maser, Pascal; Hosoo, Yoshihiro; Goshima, Shinobu; Horie, Tomoaki; Eckelman, Brendan; Yamada, ... | P42ES010337 | Proc Natl Acad Sci U S A (2002 Apr 30) | 11959905 | 2002 |
Hypersensitivity of abscisic acid-induced cytosolic calcium increases in the Arabidopsis farnesyltra ... | Allen, Gethyn J; Murata, Yoshiyuki; Chu, Sarah P; Nafisi, Majse; Schroeder, Julian I | P42ES010337 | Plant Cell (2002 Jul) | 12119381 | 2002 |
Identification and functional characterization of UDP-glucuronosyltransferases UGT1A8*1, UGT1A8*2 an ... | Huang, Yue-Hua; Galijatovic, Alema; Nguyen, Nghia; Geske, Donald; Beaton, Deirdre; Green, Judi ... | P42ES010337 | Pharmacogenetics (2002 Jun) | 12042666 | 2002 |
Inhibitors of different structure induce distinguishing conformations in the omega loop, Cys69-Cys96 ... | Shi, Jianxin; Radic', Zoran; Taylor, Palmer | P42ES010337 | J Biol Chem (2002 Nov 08) | 12196517 | 2002 |
Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition. | Park, Jin Mo; Greten, Florian R; Li, Zhi-Wei; Karin, Michael | P42ES010337 | Science (2002 Sep 20) | 12202685 | 2002 |
Mice with a homozygous deletion of the Mgat2 gene encoding UDP-N-acetylglucosamine:alpha-6-D-mannosi ... | Wang, Yan; Schachter, Harry; Marth, Jamey D | P42ES010337 | Biochim Biophys Acta (2002 Dec 19) | 12417412 | 2002 |
Regulation of cytokine expression by ligands of peroxisome proliferator activated receptors. | Cunard, Robyn; Ricote, Mercedes; DiCampli, Dennis; Archer, D Clay; Kahn, Daniel A; Glass, Chri ... | P42ES010337 | J Immunol (2002 Mar 15) | 11884448 | 2002 |
WY14,643, a PPAR alpha ligand, has profound effects on immune responses in vivo. | Cunard, Robyn; DiCampli, Dennis; Archer, D Clay; Stevenson, Jennifer L; Ricote, Mercedes; Glass ... | P42ES010337 | J Immunol (2002 Dec 15) | 12471112 | 2002 |
An integrated Arabidopsis annotation database for Affymetrix Genechip data analysis, and tools for r ... | Ghassemian, M; Waner, D; Tchieu, J; Gribskov, M; Schroeder, J I | P42ES010337 | Trends Plant Sci (2001 Oct) | 11590042 | 2001 |
Caenorhabditis elegans expresses a functional phytochelatin synthase. | Clemens, S; Schroeder, J I; Degenkolb, T | P42ES010337 | Eur J Biochem (2001 Jul) | 11432729 | 2001 |
DNA microarray analysis of gene expression in endothelial cells in response to 24-h shear stress. | Chen, B P; Li, Y S; Zhao, Y; Chen, K D; Li, S; Lao, J; Yuan, S; Shyy, J Y; Chien, S | P42ES010337 | Physiol Genomics (2001 Oct 10) | 11595792 | 2001 |
Enzymatic manganese(II) oxidation by a marine alpha-proteobacterium. | Francis, C A; Co, E M; Tebo, B M | P42ES010337 | Appl Environ Microbiol (2001 Sep) | 11526000 | 2001 |
Functional pleiotropy of an intramolecular triplex-forming fragment from the 3'-UTR of the rat Pigr ... | Fabregat, I; Koch, K S; Aoki, T; Atkinson, A E; Dang, H; Amosova, O; Fresco, J R; Schildkraut ... | P42ES010337 | Physiol Genomics (2001 Mar 8) | 11242589 | 2001 |
Modeling human congenital disorder of glycosylation type IIa in the mouse: conservation of asparagin ... | Wang, Y; Tan, J; Sutton-Smith, M; Ditto, D; Panico, M; Campbell, R M; Varki, N M; Long, J M; ... | P42ES010337 | Glycobiology (2001 Dec) | 11805078 | 2001 |
Structural organization of the microsomal glutathione S-transferase gene (MGST1) on chromosome 12p13 ... | Kelner, M J; Bagnell, R D; Montoya, M A; Estes, L A; Forsberg, L; Morgenstern, R | P42ES010337 | J Biol Chem (2000 Apr 28) | 10777602 | 2000 |