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Who We Fund: Publication Detail

Project Title: DETECTION AND MODELS OF TOXICANT EXPOSURE
PI: Tukey, Robert H
Institution: University Of California, San Diego
Grant Number: P42ES010337

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Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Adaptation of the brainwriting premortem technique to inform the co-creation of COVID-19 testing str ...   Rabin, Borsika A; Cain, Kelli L; Ayers, Lawrence O; Lomeli, Angel; Escoto, Arleth; Burola, Mar ... P42ES010337 BMC Health Serv Res (2024 Jan 03) 38172787 Exiting the NIEHS site 2024 
From NAFLD to MASLD: implications of the new nomenclature for preclinical and clinical research.   Hsu, Cynthia L; Loomba, Rohit P42ES010337 Nat Metab (2024 Feb 21) 38383845 Exiting the NIEHS site 2024 
NASH is the Leading Cause of Hepatocellular Carcinoma in Liver Transplant Candidates.   Koh, Jia Hong; Ng, Cheng Han; Nah, Benjamin; Tan, Darren Jun Hao; Loomba, Rohit; Huang, Daniel ... P42ES010337 Clin Gastroenterol Hepatol (2024 Jan) 37245718 Exiting the NIEHS site 2024 
Role of Hepatic Stellate and Liver Sinusoidal Endothelial Cells in a Human Primary Cell Three-Dimens ...   Tan, Philip K; Ostertag, Traci; Rosenthal, Sara B; Chilin-Fuentes, Daisy; Aidnik, Haylee; Linke ... P42ES010337 Am J Pathol (2024 Mar) 38158078 Exiting the NIEHS site 2024 
The Origin and Fate of Liver Myofibroblasts.   Kim, Hyun Young; Sakane, Sadatsugu; Eguileor, Alvaro; Carvalho Gontijo Weber, Raquel; Lee, Wons ... P42ES010337 Cell Mol Gastroenterol Hepatol (2024) 37743012 Exiting the NIEHS site 2024 
A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer.   Antal, Corina E; Oh, Tae Gyu; Aigner, Stefan; Luo, En-Ching; Yee, Brian A; Campos, Tania; Tiri ... P42ES010337 Nat Commun (2023 Sep 06) 37673892 Exiting the NIEHS site 2023 
Candida albicans-specific Th17 cell-mediated response contributes to alcohol-associated liver diseas ...   Zeng, Suling; Rosati, Elisa; Saggau, Carina; Messner, Berith; Chu, Huikuan; Duan, Yi; Hartmann ... P42ES010337 Cell Host Microbe (2023 Mar 08) 36893735 Exiting the NIEHS site 2023 
Factors associated with COVID-19 vaccine uptake in a US/Mexico border community: demographics, previ ...   Lomeli, Angel; Escoto, Arleth A; Reyes, Breanna; Burola, Maria Linda M; Tinoco-Calvillo, Stephe ... P42ES010337 Front Public Health (2023) 37575117 Exiting the NIEHS site 2023 
Fibrosis Progression Rate in Biopsy-Proven Nonalcoholic Fatty Liver Disease Among People With Diabet ...   Huang, Daniel Q; Wilson, Laura A; Behling, Cynthia; Kleiner, David E; Kowdley, Kris V; Dasarath ... P42ES010337 Gastroenterology (2023 Aug) 37127100 Exiting the NIEHS site 2023 
Global epidemiology of alcohol-associated cirrhosis and HCC: trends, projections and risk factors.   Huang, Daniel Q; Mathurin, Philippe; Cortez-Pinto, Helena; Loomba, Rohit P42ES010337 Nat Rev Gastroenterol Hepatol (2023 Jan) 36258033 Exiting the NIEHS site 2023 
Hepatocellular Carcinoma Incidence in Alcohol-Associated Cirrhosis: Systematic Review and Meta-analy ...   Huang, Daniel Q; Tan, Darren J H; Ng, Cheng Han; Amangurbanova, Maral; Sutter, Nancy; Lin Tay, ... P42ES010337 Clin Gastroenterol Hepatol (2023 May) 35940513 Exiting the NIEHS site 2023 
Heterozygous mutations in SOX2 may cause idiopathic hypogonadotropic hypogonadism via dominant-negat ...   Cassin, Jessica; Stamou, Maria I; Keefe, Kimberly W; Sung, Kaitlin E; Bojo, Celine C; Tonsfeldt ... P42ES010337 JCI Insight (2023 Feb 08) 36602867 Exiting the NIEHS site 2023 
Isolation of primary human liver cells from normal and nonalcoholic steatohepatitis livers.   Liu, Xiao; Lam, Kevin; Zhao, Huayi; Sakane, Sadatsugu; Kim, Hyun Young; Eguileor, Alvaro; Digg ... P42ES010337 STAR Protoc (2023 Sep 15) 37405925 Exiting the NIEHS site 2023 
Liver stiffness thresholds to predict disease progression and clinical outcomes in bridging fibrosis ...   Loomba, Rohit; Huang, Daniel Q; Sanyal, Arun J; Anstee, Quentin Mark; Trauner, Michael; Lawitz, ... P42ES010337 Gut (2023 Mar) 36750244 Exiting the NIEHS site 2023 
Meta-analysis: Chemoprevention of hepatocellular carcinoma with statins, aspirin and metformin.   Zeng, Rebecca W; Yong, Jie Ning; Tan, Darren J H; Fu, Clarissa E; Lim, Wen Hui; Xiao, Jieling; ... P42ES010337 Aliment Pharmacol Ther (2023 Mar) 36625733 Exiting the NIEHS site 2023 
Meta-analysis: Prevalence of significant or advanced fibrosis in adults with alpha-1-antitrypsin def ...   Huang, Daniel Q; Chan, Kai En; Tan, Caitlyn; Zeng, Rebecca Wenling; Koh, Benjamin; Ong, Elden ... P42ES010337 Aliment Pharmacol Ther (2023 Jul) 37089038 Exiting the NIEHS site 2023 
Oral arsenic administration to humanizedUDP-glucuronosyltransferase1 neonatal mice induces UGT1A1 th ...   Yang, Xiaojing; Weber, André A; Mennillo, Elvira; Paszek, Miles; Wong, Samantha; Le, Sabrina; ... P42ES010337, R21ES034630 J Biol Chem (2023 Mar) 36720308 Exiting the NIEHS site 2023 
Prevalence and factors associated with liver fibrosis among first-degree relatives of Mexican Americ ...   Sharpton, Suzanne; Shan, Kuangda; Bettencourt, Ricki; Lee, Miryoung; McCormick, Joseph B; Fishe ... P42ES010337 Aliment Pharmacol Ther (2023 Feb) 36628455 Exiting the NIEHS site 2023 
Psoriatic disease and non-alcoholic fatty liver disease shared pathogenesis review.   Torosian, Kelly; Lal, Esha; Kavanaugh, Arthur; Loomba, Rohit; Ajmera, Veeral; Guma, Monica P42ES010337 Semin Arthritis Rheum (2023 Apr) 36716599 Exiting the NIEHS site 2023 
Ramipril for the Treatment of COVID-19: RAMIC, a Randomized, Double-Blind, Placebo-Controlled Clinic ...   Huang, Daniel Q; Ajmera, Veeral; Tomaszewski, Christian; LaFree, Andrew; Bettencourt, Ricki; Th ... P42ES010337 Adv Ther (2023 Nov) 37615850 Exiting the NIEHS site 2023 
Review article: Available modalities for screening and imaging diagnosis of hepatocellular carcinoma ...   Barnard Giustini, Abbey; Ioannou, George N; Sirlin, Claude; Loomba, Rohit P42ES010337 Aliment Pharmacol Ther (2023 May) 37038283 Exiting the NIEHS site 2023 
Review article: the role of HSD17B13 on global epidemiology, natural history, pathogenesis and treat ...   Amangurbanova, Maral; Huang, Daniel Q; Loomba, Rohit P42ES010337 Aliment Pharmacol Ther (2023 Jan) 36349732 Exiting the NIEHS site 2023 
The transcription factor VAX1 in VIP neurons of the suprachiasmatic nucleus impacts circadian rhythm ...   Van Loh, Brooke M; Yaw, Alexandra M; Breuer, Joseph A; Jackson, Brooke; Nguyen, Duong; Jang, K ... P42ES010337 Front Endocrinol (Lausanne) (2023) 38205198 Exiting the NIEHS site 2023 
Therapeutic blockade of ER stress and inflammation prevents NASH and progression to HCC.   Boslem, Ebru; Reibe, Saskia; Carlessi, Rodrigo; Smeuninx, Benoit; Tegegne, Surafel; Egan, Case ... P42ES010337 Sci Adv (2023 Sep 15) 37703359 Exiting the NIEHS site 2023 
Type 2 diabetes, hepatic decompensation, and hepatocellular carcinoma in patients with non-alcoholic ...   Huang, Daniel Q; Noureddin, Nabil; Ajmera, Veeral; Amangurbanova, Maral; Bettencourt, Ricki; Tr ... P42ES010337 Lancet Gastroenterol Hepatol (2023 Sep) 37419133 Exiting the NIEHS site 2023 
Using ethnographic approaches to document, evaluate, and facilitate virtual community-engaged implem ...   Rabin, Borsika A; Cain, Kelli L; Salgin, Linda; Watson Jr, Paul L; Oswald, William; Kaiser, Bo ... P42ES010337 BMC Public Health (2023 Feb 28) 36855118 Exiting the NIEHS site 2023 
Zinc accumulation in Atriplex lentiformis is driven by plant genes and the soil microbiome.   Kushwaha, Priyanka; Tran, Alexandria; Quintero, Diego; Song, Miranda; Yu, Qi; Yu, Ruth; Downes ... P42ES004940, P42ES010337 Sci Total Environ (2023 Nov 15) 37478925 Exiting the NIEHS site 2023 
Aberrant iron distribution via hepatocyte-stellate cell axis drives liver lipogenesis and fibrosis.   Gao, Hong; Jin, Zhongmou; Bandyopadhyay, Gautam; Wang, Gaowei; Zhang, Dinghong; Rocha, Karina ... P42ES010337 Cell Metab (2022 Aug 02) 35921818 Exiting the NIEHS site 2022 
Changing global epidemiology of liver cancer from 2010 to 2019: NASH is the fastest growing cause of ...   Huang, Daniel Q; Singal, Amit G; Kono, Yuko; Tan, Darren J H; El-Serag, Hashem B; Loomba, Rohi ... P42ES010337 Cell Metab (2022 Jul 05) 35793659 Exiting the NIEHS site 2022 
Circadian Rhythms in the Neuronal Network Timing the Luteinizing Hormone Surge.   Tonsfeldt, Karen J; Mellon, Pamela L; Hoffmann, Hanne M P42ES010337 Endocrinology (2022 Feb 01) 34967900 Exiting the NIEHS site 2022 
Co-creating a Theory of Change to advance COVID-19 testing and vaccine uptake in underserved communi ...   Stadnick, Nicole A; Cain, Kelli L; Oswald, William; Watson, Paul; Ibarra, Marina; Lagoc, Rapha ... P42ES010337 Health Serv Res (2022 Jun) 35243622 Exiting the NIEHS site 2022 
Combined effects of host genetics and diet on human gut microbiota and incident disease in a single ...   Qin, Youwen; Havulinna, Aki S; Liu, Yang; Jousilahti, Pekka; Ritchie, Scott C; Tokolyi, Alex; ... P42ES010337 Nat Genet (2022 Feb) 35115689 Exiting the NIEHS site 2022 
Comparative efficacy of an optimal exam between ultrasound versus abbreviated MRI for HCC screening ...   Huang, Daniel Q; Fowler, Kathryn J; Liau, Joy; Cunha, Guilherme M; Louie, Ashley L; An, Julie ... P42ES010337 Aliment Pharmacol Ther (2022 Apr) 35229334 Exiting the NIEHS site 2022 
Deletion of Six3 in post-proliferative neurons produces weakened SCN circadian output, improved meta ...   Meadows, Jason D; Breuer, Joseph A; Lavalle, Shanna N; Hirschenberger, Michael R; Patel, Meera ... P42ES010337 Mol Metab (2022 Mar) 34974160 Exiting the NIEHS site 2022 
Deletion of the homeodomain gene Six3 from kisspeptin neurons causes subfertility in female mice.   Lavalle, Shanna N; Chou, Teresa; Hernandez, Jacqueline; Naing, Nay Chi P; He, Michelle Y; Tonsf ... P42ES010337 Mol Cell Endocrinol (2022 Apr 15) 35121076 Exiting the NIEHS site 2022 
Early prediction of incident liver disease using conventional risk factors and gut-microbiome-augmen ...   Liu, Yang; Méric, Guillaume; Havulinna, Aki S; Teo, Shu Mei; Åberg, Fredrik; Ruuskanen, Matti; ... P42ES010337 Cell Metab (2022 May 03) 35354069 Exiting the NIEHS site 2022 
Editorial: screening for hepatocellular carcinoma in NAFLD cirrhosis-towards abbreviated MRI alterna ...   Huang, Daniel Q; Loomba, Rohit P42ES010337 Aliment Pharmacol Ther (2022 May) 35429041 Exiting the NIEHS site 2022 
Emerging advances in the pharmacologic treatment of nonalcoholic steatohepatitis and related cirrhos ...   Sinakos, Emmanouil; Liava, Christina; Loomba, Rohit P42ES010337 Ann Gastroenterol (2022) 35599922 Exiting the NIEHS site 2022 
Engaging Underserved Communities in COVID-19 Health Equity Implementation Research: An Analysis of C ...   Stadnick, Nicole A; Cain, Kelli L; Watson, Paul; Oswald, William; Ibarra, Marina; Lagoc, Rapha ... P42ES010337 Front Health Serv (2022) 36258685 Exiting the NIEHS site 2022 
Expert Panel Review to Compare FDA and EMA Guidance on Drug Development and Endpoints in Nonalcoholi ...   Loomba, Rohit; Ratziu, Vlad; Harrison, Stephen A; NASH Clinical Trial Design International Workin ... P42ES010337 Gastroenterology (2022 Mar) 34822801 Exiting the NIEHS site 2022 
Female fertility does not require Bmal1 in suprachiasmatic nucleus neurons expressing arginine vasop ...   Tonsfeldt, Karen J; Cui, Laura J; Lee, Jinkwon; Walbeek, Thijs J; Brusman, Liza E; Jin, Ye; Mi ... P42ES010337 Front Endocrinol (Lausanne) (2022) 35992114 Exiting the NIEHS site 2022 
FGF1 and insulin control lipolysis by convergent pathways.   Sancar, Gencer; Liu, Sihao; Gasser, Emanuel; Alvarez, Jacqueline G; Moutos, Christopher; Kim, ... P42ES010337 Cell Metab (2022 Jan 04) 34986332 Exiting the NIEHS site 2022 
FXR mediates ILC-intrinsic responses to intestinal inflammation.   Fu, Ting; Li, Yuwenbin; Oh, Tae Gyu; Cayabyab, Fritz; He, Nanhai; Tang, Qin; Coulter, Sally; ... P42ES010337 Proc Natl Acad Sci U S A (2022 Dec 20) 36508655 Exiting the NIEHS site 2022 
Gut metagenome-derived signature predicts hepatic decompensation and mortality in NAFLD-related cirr ...   Sharpton, Suzanne R; Oh, Tae Gyu; Madamba, Egbert; Wang, Chenjingyi; Yu, Ruth T; Atkins, Annet ... P42ES010337 Aliment Pharmacol Ther (2022 Nov) 36164267 Exiting the NIEHS site 2022 
Hepatocellular Carcinoma Risk Assessment for Patients With Advanced Fibrosis After Eradication of He ...   Tamaki, Nobuharu; Kurosaki, Masayuki; Yasui, Yutaka; Mori, Nami; Tsuji, Keiji; Hasebe, Chitomi ... P42ES010337 Hepatol Commun (2022 Mar) 34676692 Exiting the NIEHS site 2022 
Interorgan crosstalk in pancreatic islet function and pathology.   Evans, Ronald M; Wei, Zong P42ES010337 FEBS Lett (2022 Mar) 35014695 Exiting the NIEHS site 2022 
Intestinal UDP-Glucuronosyltransferase 1A1 and Protection against Irinotecan-Induced Toxicity in a N ...   Mennillo, Elvira; Yang, Xiaojing; Weber, Andre A; Maruo, Yoshihiro; Verreault, Melanie; Barbier ... P42ES010337 Drug Metab Dispos (2022 Jan) 34697081 Exiting the NIEHS site 2022 
Lactational delivery of Triclosan promotes non-alcoholic fatty liver disease in newborn mice.   Weber, André A; Yang, Xiaojing; Mennillo, Elvira; Ding, Jeffrey; Watrous, Jeramie D; Jain, Moh ... P42ES010337 Nat Commun (2022 Jul 27) 35896521 Exiting the NIEHS site 2022 
Liver Fat Assessment in Multiview Sonography Using Transfer Learning With Convolutional Neural Netwo ...   Byra, Michal; Han, Aiguo; Boehringer, Andrew S; Zhang, Yingzhen N; O'Brien Jr, William D; Erdma ... P42ES010337 J Ultrasound Med (2022 Jan) 33749862 Exiting the NIEHS site 2022 
Magnetic resonance elastography plus Fibrosis-4 versus FibroScan-aspartate aminotransferase in detec ...   Tamaki, Nobuharu; Imajo, Kento; Sharpton, Suzanne; Jung, Jinho; Kawamura, Nobuyoshi; Yoneda, M ... P42ES010337 Hepatology (2022 Mar) 34496054 Exiting the NIEHS site 2022 
Metabolic Injury of Hepatocytes Promotes Progression of NAFLD and AALD.   Carvalho-Gontijo, Raquel; Han, Cuijuan; Zhang, Lei; Zhang, Vivian; Hosseini, Mojgan; Mekeel, K ... P42ES010337 Semin Liver Dis (2022 Aug) 36001995 Exiting the NIEHS site 2022 
MiR-690 treatment causes decreased fibrosis and steatosis and restores specific Kupffer cell functio ...   Gao, Hong; Jin, Zhongmou; Bandyopadhyay, Gautam; Cunha E Rocha, Karina; Liu, Xiao; Zhao, Huayi ... P42ES010337 Cell Metab (2022 Jul 05) 35700738 Exiting the NIEHS site 2022 
Non-invasive methods for imaging hepatic steatosis and their clinical importance in NAFLD.   Tamaki, Nobuharu; Ajmera, Veeral; Loomba, Rohit P42ES010337 Nat Rev Endocrinol (2022 Jan) 34815553 Exiting the NIEHS site 2022 
Noninvasive Risk Stratification for Nonalcoholic Fatty Liver Disease Among Living Liver Donor Candid ...   Danis, Nilay; Weeks, Sharon R; Kim, Ahyoung; Baghdadi, Azarakhsh; Ghadimi, Maryam; Kamel, Ihab ... P42ES010337 Liver Transpl (2022 Apr) 34753223 Exiting the NIEHS site 2022 
Obesity alters pathology and treatment response in inflammatory disease.   Bapat, Sagar P; Whitty, Caroline; Mowery, Cody T; Liang, Yuqiong; Yoo, Arum; Jiang, Zewen; Pet ... P42ES010337 Nature (2022 Apr) 35355021 Exiting the NIEHS site 2022 
PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to s ...   Kim, Ju Youn; Wang, Lily Q; Sladky, Valentina C; Oh, Tae Gyu; Liu, Junlai; Trinh, Kaitlyn; Eic ... P42ES010337 Cell Metab (2022 Oct 04) 36041455 Exiting the NIEHS site 2022 
Plant hormone regulation of abiotic stress responses.   Waadt, Rainer; Seller, Charles A; Hsu, Po-Kai; Takahashi, Yohei; Munemasa, Shintaro; Schroeder, ... P42ES010337 Nat Rev Mol Cell Biol (2022 Oct) 35513717 Exiting the NIEHS site 2022 
Review article: current and emerging therapies for the management of cirrhosis and its complications ...   Tapper, Elliot B; Ufere, Nneka N; Huang, Daniel Q; Loomba, Rohit P42ES010337 Aliment Pharmacol Ther (2022 May) 35235219 Exiting the NIEHS site 2022 
Shared Mechanisms between Cardiovascular Disease and NAFLD.   Huang, Daniel Q; Downes, Michael; Evans, Ronald M; Witztum, Joseph L; Glass, Christopher K; Loo ... P42ES010337 Semin Liver Dis (2022 Nov) 36008083 Exiting the NIEHS site 2022 
Treatment Candidacy for Pharmacologic Therapies for NASH.   Rowe, Ian A; Wong, Vincent Wai-Sun; Loomba, Rohit P42ES010337 Clin Gastroenterol Hepatol (2022 06) 33711479 Exiting the NIEHS site 2022 
Understanding implementation research collaborations from a co-creation lens: Recommendations for a ...   Pérez Jolles, Mónica; Willging, Cathleen E; Stadnick, Nicole A; Crable, Erika L; Lengnick-Hall, ... P42ES010337 Front Health Serv (2022) 36908715 Exiting the NIEHS site 2022 
"Sweet death": Fructose as a metabolic toxin that targets the gut-liver axis.   Febbraio, Mark A; Karin, Michael P42ES010337 Cell Metab (2021 12 07) 34619076 Exiting the NIEHS site 2021 
A role for calcium-dependent protein kinases in differential CO2 - and ABA-controlled stomatal closi ...   Schulze, Sebastian; Dubeaux, Guillaume; Ceciliato, Paulo H O; Munemasa, Shintaro; Nuhkat, Maris ... P42ES010337 New Phytol (2021 03) 33187027 Exiting the NIEHS site 2021 
Administrative Coding in Electronic Health Care Record-Based Research of NAFLD: An Expert Panel Cons ...   Hagström, Hannes; Adams, Leon A; Allen, Alina M; Byrne, Christopher D; Chang, Yoosoo; Grønbaek, ... P42ES010337 Hepatology (2021 07) 33486773 Exiting the NIEHS site 2021 
Alterations in bile acid metabolizing gut microbiota and specific bile acid genes as a precision med ...   Jiao, Na; Loomba, Rohit; Yang, Zi-Huan; Wu, Dingfeng; Fang, Sa; Bettencourt, Richele; Lan, Pi ... P42ES010337 Physiol Genomics (2021 08 01) 34151600 Exiting the NIEHS site 2021 
An amiRNA screen uncovers redundant CBF and ERF34/35 transcription factors that differentially regul ...   Xie, Qingqing; Yu, Qi; Jobe, Timothy O; Pham, Allis; Ge, Chennan; Guo, Qianqian; Liu, Jianxiu ... P42ES010337 Plant Cell Environ (2021 05) 33554343 Exiting the NIEHS site 2021 
Androgen receptor positively regulates gonadotropin-releasing hormone receptor in pituitary gonadotr ...   Ryan, Genevieve E; Bohaczuk, Stephanie C; Cassin, Jessica; Witham, Emily A; Shojaei, Shadi; Ho, ... P42ES010337 Mol Cell Endocrinol (2021 06 15) 33872733 Exiting the NIEHS site 2021 
Associations of healthy food choices with gut microbiota profiles.   Koponen, Kari K; Salosensaari, Aaro; Ruuskanen, Matti O; Havulinna, Aki S; Männistö, Satu; Jous ... P42ES010337 Am J Clin Nutr (2021 Aug 02) 34020448 Exiting the NIEHS site 2021 
Bisphenol A derivatives act as novel coactivator-binding inhibitors for estrogen receptor β.   Iwamoto, Masaki; Masuya, Takahiro; Hosose, Mari; Tagawa, Koki; Ishibashi, Tomoka; Suyama, Keit ... P42ES010337 J Biol Chem (2021 Nov) 34499926 Exiting the NIEHS site 2021 
Bromodomain containing 9 (BRD9) regulates macrophage inflammatory responses by potentiating glucocor ...   Wang, Liu; Oh, Tae Gyu; Magida, Jason; Estepa, Gabriela; Obayomi, S M Bukola; Chong, Ling-Wa; ... P42ES010337 Proc Natl Acad Sci U S A (2021 08 31) 34446564 Exiting the NIEHS site 2021 
Change in Fibrosis 4 Index as Predictor of High Risk of Incident Hepatocellular Carcinoma After Erad ...   Tamaki, Nobuharu; Kurosaki, Masayuki; Yasui, Yutaka; Mori, Nami; Tsuji, Keiji; Hasebe, Chitomi ... P42ES010337 Clin Infect Dis (2021 11 02) 33544129 Exiting the NIEHS site 2021 
Change in MRI-PDFF and Histologic Response in Patients With Nonalcoholic Steatohepatitis: A Systemat ...   Stine, Jonathan G; Munaganuru, Nagambika; Barnard, Abbey; Wang, Jennifer L; Kaulback, Kellee; A ... P42ES010337 Clin Gastroenterol Hepatol (2021 11) 32882428 Exiting the NIEHS site 2021 
Clinical Care Pathway for the Risk Stratification and Management of Patients With Nonalcoholic Fatty ...   Kanwal, Fasiha; Shubrook, Jay H; Adams, Leon A; Pfotenhauer, Kim; Wai-Sun Wong, Vincent; Wright ... P42ES010337 Gastroenterology (2021 11) 34602251 Exiting the NIEHS site 2021 
Clinical Utility of Change in Nonalcoholic Fatty Liver Disease Activity Score and Change in Fibrosis ...   Tamaki, Nobuharu; Munaganuru, Nagambika; Jung, Jinho; Yonan, Aed Qas; Bettencourt, Richele; Ajm ... P42ES010337 Clin Gastroenterol Hepatol (2021 Dec) 33157318 Exiting the NIEHS site 2021 
Colon cancer checks in when bile acids check out: the bile acid-nuclear receptor axis in colon cance ...   Tang, Qin; Evans, Ronald M P42ES010337 Essays Biochem (2021 12 17) 34414429 Exiting the NIEHS site 2021 
Current Concepts, Opportunities, and Challenges of Gut Microbiome-Based Personalized Medicine in Non ...   Sharpton, S R; Schnabl, B; Knight, R; Loomba, R P42ES010337 Cell Metab (2021 Jan 05) 33296678 Exiting the NIEHS site 2021 
Distal Enhancer Potentiates Activin- and GnRH-Induced Transcription of FSHB.   Bohaczuk, Stephanie C; Cassin, Jessica; Slaiwa, Theresa I; Thackray, Varykina G; Mellon, Pamela ... P42ES010337 Endocrinology (2021 07 01) 33824966 Exiting the NIEHS site 2021 
Emerging Metabolic and Transcriptomic Signature of PNPLA3-Associated NASH.   Dhar, Debanjan; Loomba, Rohit P42ES010337 Hepatology (2021 Apr) 33544416 Exiting the NIEHS site 2021 
Emerging Role of Genomic Analysis in Clinical Evaluation of Lean Individuals With NAFLD.   Vilarinho, Sílvia; Ajmera, Veeral; Zheng, Melanie; Loomba, Rohit P42ES010337 Hepatology (2021 10) 34233030 Exiting the NIEHS site 2021 
FGF21 promotes thermogenic gene expression as an autocrine factor in adipocytes.   Abu-Odeh, Mohammad; Zhang, Yuan; Reilly, Shannon M; Ebadat, Nima; Keinan, Omer; Valentine, Jos ... P42ES010337 Cell Rep (2021 Jun 29) 34192547 Exiting the NIEHS site 2021 
From Liver Fat to Cancer: Perils of the Western Diet.   Kim, Ju Youn; He, Feng; Karin, Michael P42ES010337 Cancers (Basel) (2021 Mar 04) 33806428 Exiting the NIEHS site 2021 
FSHB  Transcription is Regulated by a Novel 5' Distal Enhancer With a Fertility-Associated Single Nu ...   Bohaczuk, Stephanie C; Thackray, Varykina G; Shen, Jia; Skowronska-Krawczyk, Dorota; Mellon, Pa ... P42ES010337 Endocrinology (2021 01 01) 33009549 Exiting the NIEHS site 2021 
Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention.   Huang, Daniel Q; El-Serag, Hashem B; Loomba, Rohit P42ES010337 Nat Rev Gastroenterol Hepatol (2021 04) 33349658 Exiting the NIEHS site 2021 
Growth Hormone Pulses and Liver Gene Expression Are Differentially Regulated by the Circadian Clock ...   Schoeller, Erica L; Tonsfeldt, Karen J; Sinkovich, McKenna; Shi, Rujing; Mellon, Pamela L P42ES010337 Endocrinology (2021 04 01) 33539533 Exiting the NIEHS site 2021 
Hepatic Fibrosis Associates With Multiple Cardiometabolic Disease Risk Factors: The Framingham Heart ...   Long, Michelle T; Zhang, Xiaoyu; Xu, Hanfei; Liu, Ching-Ti; Corey, Kathleen E; Chung, Raymond ... P42ES010337 Hepatology (2021 Feb) 33125745 Exiting the NIEHS site 2021 
Heterogeneity of HSCs in a Mouse Model of NASH.   Rosenthal, Sara Brin; Liu, Xiao; Ganguly, Souradipta; Dhar, Debanjan; Pasillas, Martina P; Ricc ... P42ES010337 Hepatology (2021 Aug) 33550587 Exiting the NIEHS site 2021 
Identification and characterization of SaeIF1 from the eukaryotic translation factor SUI1 family in ...   Yu, Qi; Zhang, Zhong-Chun; Wang, Miao-Yu; Scavo, Alexander; Schroeder, Julian I; Qiu, Bao-Shen ... P42ES010337 Planta (2021 Jan 03) 33389204 Exiting the NIEHS site 2021 
Imaging biomarkers of NAFLD, NASH, and fibrosis.   Ajmera, Veeral; Loomba, Rohit P42ES010337 Mol Metab (2021 08) 33460786 Exiting the NIEHS site 2021 
Intestinal α1-2-Fucosylation Contributes to Obesity and Steatohepatitis in Mice.   Zhou, Rongrong; Llorente, Cristina; Cao, Jinling; Zaramela, Livia S; Zeng, Suling; Gao, Bei; L ... P42ES010337 Cell Mol Gastroenterol Hepatol (2021) 33631374 Exiting the NIEHS site 2021 
Kiss1 is differentially regulated in male and female mice by the homeodomain transcription factor VA ...   Lavalle, Shanna N; Chou, Teresa; Hernandez, Jacqueline; Naing, Nay Chi P; Tonsfeldt, Karen J; H ... P42ES010337 Mol Cell Endocrinol (2021 08 20) 34098016 Exiting the NIEHS site 2021 
Links between gut microbiome composition and fatty liver disease in a large population sample.   Ruuskanen, Matti O; Åberg, Fredrik; Männistö, Ville; Havulinna, Aki S; Méric, Guillaume; Liu, ... P42ES010337 Gut Microbes (2021 Jan-Dec) 33651661 Exiting the NIEHS site 2021 
Liver stiffness by magnetic resonance elastography is associated with increased risk of cardiovascul ...   Park, Jung Gil; Jung, Jinho; Verma, Kritin K; Kang, Min Kyu; Madamba, Egbert; Lopez, Scarlett; ... P42ES010337 Aliment Pharmacol Ther (2021 05) 33764550 Exiting the NIEHS site 2021 
Machine learning enables new insights into genetic contributions to liver fat accumulation.   Haas, Mary E; Pirruccello, James P; Friedman, Samuel N; Wang, Minxian; Emdin, Connor A; Ajmera, ... P42ES010337 Cell Genom (2021 Dec 08) 34957434 Exiting the NIEHS site 2021 
Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation ...   Xian, Hongxu; Liu, Yuan; Rundberg Nilsson, Alexandra; Gatchalian, Raphaella; Crother, Timothy R ... P42ES010337 Immunity (2021 Jul 13) 34115964 Exiting the NIEHS site 2021 
Molecular mechanisms of stomatal closure in response to rising vapour pressure deficit.   Jalakas, Pirko; Takahashi, Yohei; Waadt, Rainer; Schroeder, Julian I; Merilo, Ebe P42ES010337 New Phytol (2021 10) 34197630 Exiting the NIEHS site 2021 
MRE combined with FIB-4 (MEFIB) index in detection of candidates for pharmacological treatment of NA ...   Jung, Jinho; Loomba, Rohan R; Imajo, Kento; Madamba, Egbert; Gandhi, Sanil; Bettencourt, Ricki ... P42ES010337 Gut (2021 10) 33214165 Exiting the NIEHS site 2021 
MRI-Proton Density Fat Fraction Treatment Response Criteria in Nonalcoholic Steatohepatitis.   Loomba, Rohit P42ES010337 Hepatology (2021 Mar) 33179266 Exiting the NIEHS site 2021 
Nonalcoholic fatty liver disease as a metabolic disease in humans: A literature review.   Cariou, Bertrand; Byrne, Christopher D; Loomba, Rohit; Sanyal, Arun J P42ES010337 Diabetes Obes Metab (2021 05) 33464677 Exiting the NIEHS site 2021 
Nontargeted mass spectrometry of dried blood spots for interrogation of the human circulating metabo ...   Ward, Casey; Nallamshetty, Shriram; Watrous, Jeramie D; Acres, Eowyn; Long, Tao; Mathews, Ian ... P42ES010337 J Mass Spectrom (2021 May 27) 34240506 Exiting the NIEHS site 2021 
Optimal Threshold of Controlled Attenuation Parameter for Detection of HIV-Associated NAFLD With Mag ...   Ajmera, Veeral H; Cachay, Edward R; Ramers, Christian B; Bassirian, Shirin; Singh, Seema; Bette ... P42ES010337 Clin Infect Dis (2021 06 15) 32975278 Exiting the NIEHS site 2021 
Potential of therapeutic bile acids in the treatment of neonatal Hyperbilirubinemia.   van der Schoor, Lori W E; Verkade, Henkjan J; Bertolini, Anna; de Wit, Sanne; Mennillo, Elvira; ... P42ES010337 Sci Rep (2021 May 27) 34045606 Exiting the NIEHS site 2021 
Protein kinase sensors: an overview of new designs for visualizing kinase dynamics in single plant c ...   Zhang, Li; Takahashi, Yohei; Schroeder, Julian I P42ES010337 Plant Physiol (2021 Oct 05) 35142856 Exiting the NIEHS site 2021 
Publisher Correction: Immune-evasive human islet-like organoids ameliorate diabetes.   Yoshihara, Eiji; O'Connor, Carolyn; Gasser, Emanuel; Wei, Zong; Oh, Tae Gyu; Tseng, Tiffany W; ... P42ES010337 Nature (2021 Feb) 33469222 Exiting the NIEHS site 2021 
RAMIC: Design of a randomized, double-blind, placebo-controlled trial to evaluate the efficacy of ra ...   Ajmera, Veeral; Thompson, Wesley K; Smith, Davey M; Malhotra, Atul; Mehta, Ravindra L; Tolia, ... P42ES010337 Contemp Clin Trials (2021 Apr) 33631357 Exiting the NIEHS site 2021 
Randomised clinical trial: Pemafibrate, a novel selective peroxisome proliferator-activated receptor ...   Nakajima, Atsushi; Eguchi, Yuichiro; Yoneda, Masato; Imajo, Kento; Tamaki, Nobuharu; Suganami, ... P42ES010337 Aliment Pharmacol Ther (2021 11) 34528723 Exiting the NIEHS site 2021 
Randomised clinical trial: semaglutide versus placebo reduced liver steatosis but not liver stiffnes ...   Flint, Anne; Andersen, Grit; Hockings, Paul; Johansson, Lars; Morsing, Anni; Sundby Palle, Mad ... P42ES010337 Aliment Pharmacol Ther (2021 11) 34570916 Exiting the NIEHS site 2021 
Regulation of Intestinal UDP-Glucuronosyltransferase 1A1 by the Farnesoid X Receptor Agonist Obetich ...   Weber, André A; Mennillo, Elvira; Yang, Xiaojing; van der Schoor, Lori W E; Jonker, Johan W; Ch ... P42ES010337 Drug Metab Dispos (2021 01) 33154041 Exiting the NIEHS site 2021 
Reproductive Deficits Induced by Prenatal Antimüllerian Hormone Exposure Require Androgen Receptor i ...   Ho, Emily V; Shi, Chengxian; Cassin, Jessica; He, Michelle Y; Nguyen, Ryan D; Ryan, Genevieve ... P42ES010337 Endocrinology (2021 12 01) 34529765 Exiting the NIEHS site 2021 
Signaling mechanisms in abscisic acid-mediated stomatal closure.   Hsu, Po-Kai; Dubeaux, Guillaume; Takahashi, Yohei; Schroeder, Julian I P42ES010337 Plant J (2021 01) 33145840 Exiting the NIEHS site 2021 
Systematic review with network meta-analysis: comparative efficacy of pharmacologic therapies for fi ...   Majzoub, Abdul M; Nayfeh, Tarek; Barnard, Abbey; Munaganuru, Nagambika; Dave, Shravan; Singh, ... P42ES010337 Aliment Pharmacol Ther (2021 Oct) 34435378 Exiting the NIEHS site 2021 
The Commensal Microbe Veillonella as a Marker for Response to an FGF19 Analog in NASH.   Loomba, Rohit; Ling, Lei; Dinh, Duy M; DePaoli, Alex M; Lieu, Hsiao D; Harrison, Stephen A; Sa ... P42ES010337 Hepatology (2021 01) 32794259 Exiting the NIEHS site 2021 
The impact of genetic risk on liver fibrosis in non-alcoholic fatty liver disease as assessed by mag ...   Ajmera, Veeral; Liu, Amy; Bettencourt, Ricki; Dhar, Debanjan; Richards, Lisa; Loomba, Rohit P42ES010337 Aliment Pharmacol Ther (2021 07) 33975381 Exiting the NIEHS site 2021 
The Relationship Between Type 2 Diabetes, NAFLD, and Cardiovascular Risk.   Caussy, Cyrielle; Aubin, Adrien; Loomba, Rohit P42ES010337 Curr Diab Rep (2021 03 19) 33742318 Exiting the NIEHS site 2021 
The SLIM1 transcription factor is required for arsenic resistance in Arabidopsis thaliana.   Jobe, Timothy O; Yu, Qi; Hauser, Felix; Xie, Qingqing; Meng, Yuan; Maassen, Tim; Kopriva, Sta ... P42ES010337 FEBS Lett (2021 06) 33960401 Exiting the NIEHS site 2021 
The transcription factors SIX3 and VAX1 are required for suprachiasmatic nucleus circadian output an ...   Hoffmann, Hanne M; Meadows, Jason D; Breuer, Joseph A; Yaw, Alexandra M; Nguyen, Duong; Tonsfel ... P42ES010337 J Neurosci Res (2021 10) 34212416 Exiting the NIEHS site 2021 
Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction ...   Xu, Shihao; Chaudhary, Omkar; Rodríguez-Morales, Patricia; Sun, Xiaoli; Chen, Dan; Zappasodi, ... P42ES010337 Immunity (2021 Jul 13) 34102100 Exiting the NIEHS site 2021 
A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis.   Oh, Tae Gyu; Kim, Susy M; Caussy, Cyrielle; Fu, Ting; Guo, Jian; Bassirian, Shirin; Singh, Se ... P42ES010337 Cell Metab (2020 Nov 03) 33147487 Exiting the NIEHS site 2020 
A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis.   Oh, Tae Gyu; Kim, Susy M; Caussy, Cyrielle; Fu, Ting; Guo, Jian; Bassirian, Shirin; Singh, Se ... P42ES010337 Cell Metab (2020 11 03) 32610095 Exiting the NIEHS site 2020 
Advances in non-invasive assessment of hepatic fibrosis.   Loomba, Rohit; Adams, Leon A P42ES010337 Gut (2020 07) 32066623 Exiting the NIEHS site 2020 
Advances in non-invasive biomarkers for the diagnosis and monitoring of non-alcoholic fatty liver di ...   Long, Michelle T; Gandhi, Sanil; Loomba, Rohit P42ES010337 Metabolism (2020 10) 32387227 Exiting the NIEHS site 2020 
AGA Clinical Practice Update on Screening and Surveillance for Hepatocellular Carcinoma in Patients ...   Loomba, Rohit; Lim, Joseph K; Patton, Heather; El-Serag, Hashem B P42ES010337 Gastroenterology (2020 05) 32006545 Exiting the NIEHS site 2020 
An AMPK-caspase-6 axis controls liver damage in nonalcoholic steatohepatitis.   Zhao, Peng; Sun, Xiaoli; Chaggan, Cynthia; Liao, Zhongji; In Wong, Kai; He, Feng; Singh, Seem ... P42ES010337 Science (2020 02 07) 32029622 Exiting the NIEHS site 2020 
An update on the role of the microbiome in non-alcoholic fatty liver disease pathogenesis, diagnosis ...   Mouzaki, Marialena; Loomba, Rohit P42ES010337 Curr Treat Options Gastroenterol (2020 Jun) 33716495 Exiting the NIEHS site 2020 
Assessment of Hepatic Steatosis in Nonalcoholic Fatty Liver Disease by Using Quantitative US.   Han, Aiguo; Zhang, Yingzhen N; Boehringer, Andrew S; Montes, Vivian; Andre, Michael P; Erdman J ... P42ES010337 Radiology (2020 04) 32013792 Exiting the NIEHS site 2020 
Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in ...   Xu, Jun; Ma, Hsiao-Yen; Liu, Xiao; Rosenthal, Sara; Baglieri, Jacopo; McCubbin, Ryan; Sun, Me ... P42ES010337 JCI Insight (2020 02 13) 32051339 Exiting the NIEHS site 2020 
CBASS Immunity Uses CARF-Related Effectors to Sense 3'-5'- and 2'-5'-Linked Cyclic Oligonucleotide S ...   Lowey, Brianna; Whiteley, Aaron T; Keszei, Alexander F A; Morehouse, Benjamin R; Mathews, Ian T ... P42ES010337 Cell (2020 07 09) 32544385 Exiting the NIEHS site 2020 
Clinical Research in Hepatology in the COVID-19 Pandemic and Post-Pandemic Era: Challenges and the N ...   Verna, Elizabeth C; Serper, Marina; Chu, Jaime; Corey, Kathleen; Fix, Oren K; Hoyt, Karen; Pag ... P42ES010337 Hepatology (2020 11) 32740969 Exiting the NIEHS site 2020 
Clinical Utility of an Increase in Magnetic Resonance Elastography in Predicting Fibrosis Progressio ...   Ajmera, Veeral H; Liu, Amy; Singh, Seema; Yachoa, Georg; Ramey, Matthew; Bhargava, Meera; Zama ... P42ES010337 Hepatology (2020 03) 31556124 Exiting the NIEHS site 2020 
Combination therapy for non-alcoholic steatohepatitis: rationale, opportunities and challenges.   Dufour, Jean-François; Caussy, Cyrielle; Loomba, Rohit P42ES010337 Gut (2020 Oct) 32381514 Exiting the NIEHS site 2020 
Decreased adipose tissue oxygenation associates with insulin resistance in individuals with obesity.   Cifarelli, Vincenza; Beeman, Scott C; Smith, Gordon I; Yoshino, Jun; Morozov, Darya; Beals, Jo ... P42ES010337 J Clin Invest (2020 12 01) 33164985 Exiting the NIEHS site 2020 
Differential Role of Liver X Receptor (LXR) α and LXRβ in the Regulation of UDP-Glucuronosyltransfer ...   Hansmann, Eva; Mennillo, Elvira; Yoda, Emiko; Verreault, Mélanie; Barbier, Olivier; Chen, Shuj ... P42ES010337 Drug Metab Dispos (2020 04) 31980500 Exiting the NIEHS site 2020 
Effects of Diet versus Gastric Bypass on Metabolic Function in Diabetes.   Yoshino, Mihoko; Kayser, Brandon D; Yoshino, Jun; Stein, Richard I; Reeds, Dominic; Eagon, J C ... P42ES010337 N Engl J Med (2020 Aug 20) 32813948 Exiting the NIEHS site 2020 
Evidence-based clinical advice for nutrition and dietary weight loss strategies for the management o ...   Hydes, Theresa J; Ravi, Sujan; Loomba, Rohit; E Gray, Meagan P42ES010337 Clin Mol Hepatol (2020 10) 32674529 Exiting the NIEHS site 2020 
Fructose stimulated de novo lipogenesis is promoted by inflammation.   Todoric, Jelena; Di Caro, Giuseppe; Reibe, Saskia; Henstridge, Darren C; Green, Courtney R; Vrb ... P42ES010337 Nat Metab (2020 10) 32839596 Exiting the NIEHS site 2020 
Genomic and Epigenomic Landscaping Defines New Therapeutic Targets for Adenosquamous Carcinoma of th ...   Lenkiewicz, Elizabeth; Malasi, Smriti; Hogenson, Tara L; Flores, Luis F; Barham, Whitney; Phill ... P42ES010337 Cancer Res (2020 10 15) 32928922 Exiting the NIEHS site 2020 
Global chemical effects of the microbiome include new bile-acid conjugations.   Quinn, Robert A; Melnik, Alexey V; Vrbanac, Alison; Fu, Ting; Patras, Kathryn A; Christy, Mitc ... P42ES010337 Nature (2020 Mar) 32103176 Exiting the NIEHS site 2020 
GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadot ...   Nicholas, Dequina A; Knight, Vashti S; Tonsfeldt, Karen J; Terasaka, Tomohiro; Molinar-Inglis, ... P42ES010337 Sci Rep (2020 08 03) 32747664 Exiting the NIEHS site 2020 
Glyphosate Excretion is Associated With Steatohepatitis and Advanced Liver Fibrosis in Patients With ...   Mills, Paul J; Caussy, Cyrielle; Loomba, Rohit P42ES010337 Clin Gastroenterol Hepatol (2020 03) 30954713 Exiting the NIEHS site 2020 
IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcoho ...   Ma, Hsiao-Yen; Yamamoto, Gen; Xu, Jun; Liu, Xiao; Karin, Daniel; Kim, Ju Youn; Alexandrov, Lu ... P42ES010337 J Hepatol (2020 05) 31899206 Exiting the NIEHS site 2020 
Immune-evasive human islet-like organoids ameliorate diabetes.   Yoshihara, Eiji; O'Connor, Carolyn; Gasser, Emanuel; Wei, Zong; Oh, Tae Gyu; Tseng, Tiffany W; ... P42ES010337 Nature (2020 Oct) 32814902 Exiting the NIEHS site 2020 
Initiation of Parental Genome Reprogramming in Fertilized Oocyte by Splicing Kinase SRPK1-Catalyzed ...   Gou, Lan-Tao; Lim, Do-Hwan; Ma, Wubin; Aubol, Brandon E; Hao, Yajing; Wang, Xin; Zhao, Jun; L ... P42ES010337 Cell (2020 03 19) 32169215 Exiting the NIEHS site 2020 
Intestinal Virome Signature Associated With Severity of Nonalcoholic Fatty Liver Disease.   Lang, Sonja; Demir, Münevver; Martin, Anna; Jiang, Lu; Zhang, Xinlian; Duan, Yi; Gao, Bei; Wi ... P42ES010337 Gastroenterology (2020 11) 32652145 Exiting the NIEHS site 2020 
Liver Stiffness Severity is Associated With Increased Cardiovascular Risk in Patients With Type 2 Di ...   Mangla, Neeraj; Ajmera, Veeral H; Caussy, Cyrielle; Sirlin, Claude; Brouha, Sharon; Bajwa-Dulai ... P42ES010337 Clin Gastroenterol Hepatol (2020 03) 31100460 Exiting the NIEHS site 2020 
MAP3Kinase-dependent SnRK2-kinase activation is required for abscisic acid signal transduction and r ...   Takahashi, Yohei; Zhang, Jingbo; Hsu, Po-Kai; Ceciliato, Paulo H O; Zhang, Li; Dubeaux, Guilla ... P42ES010337 Nat Commun (2020 01 02) 31896774 Exiting the NIEHS site 2020 
Mechanisms of liver fibrosis and its role in liver cancer.   Dhar, Debanjan; Baglieri, Jacopo; Kisseleva, Tatiana; Brenner, David A P42ES010337 Exp Biol Med (Maywood) (2020 Jan) 31924111 Exiting the NIEHS site 2020 
Monitoring and mitigation of toxic heavy metals and arsenic accumulation in food crops: A case study ...   Cooper, Andrew M; Felix, Didra; Alcantara, Fatima; Zaslavsky, Ilya; Work, Amy; Watson, Paul L; ... P42ES010337 Plant Direct (2020 Jan) 31956855 Exiting the NIEHS site 2020 
NCoR1 Protects Mice From Dextran Sodium Sulfate-Induced Colitis by Guarding Colonic Crypt Cells From ...   Mennillo, Elvira; Yang, Xiaojing; Paszek, Miles; Auwerx, Johan; Benner, Christopher; Chen, Shu ... P42ES010337 Cell Mol Gastroenterol Hepatol (2020) 32044398 Exiting the NIEHS site 2020 
Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis.   Sun, Xiaoli; Seidman, Jason S; Zhao, Peng; Troutman, Ty D; Spann, Nathanael J; Que, Xuchu; Zho ... P42ES010337 Cell Metab (2020 01 07) 31761566 Exiting the NIEHS site 2020 
NF-κB-p62-NRF2 survival signaling is associated with high ROR1 expression in chronic lymphocytic leu ...   Sanchez-Lopez, Elsa; Ghia, Emanuela M; Antonucci, Laura; Sharma, Natasha; Rassenti, Laura Z; Xu ... P42ES010337 Cell Death Differ (2020 07) 31992855 Exiting the NIEHS site 2020 
Noninvasive Diagnosis of Nonalcoholic Fatty Liver Disease and Quantification of Liver Fat with Radio ...   Han, Aiguo; Byra, Michal; Heba, Elhamy; Andre, Michael P; Erdman Jr, John W; Loomba, Rohit; Si ... P42ES010337 Radiology (2020 05) 32096706 Exiting the NIEHS site 2020 
NRF2 activates growth factor genes and downstream AKT signaling to induce mouse and human hepatomega ...   He, Feng; Antonucci, Laura; Yamachika, Shinichiro; Zhang, Zechuan; Taniguchi, Koji; Umemura, A ... P42ES010337 J Hepatol (2020 06) 32105670 Exiting the NIEHS site 2020 
NRF2 as a regulator of cell metabolism and inflammation in cancer.   He, Feng; Antonucci, Laura; Karin, Michael P42ES010337 Carcinogenesis (2020 06 17) 32347301 Exiting the NIEHS site 2020 
NRF2-Independent Regulation of Intestinal Constitutive Androstane Receptor by the Pro-Oxidants Cadmi ...   Paszek, Miles; Tukey, Robert H P42ES010337 Drug Metab Dispos (2020 01) 31704714 Exiting the NIEHS site 2020 
PNPLA3 Genotype and Risk of Liver and All-Cause Mortality.   Stender, Stefan; Loomba, Rohit P42ES010337 Hepatology (2020 03) 31954067 Exiting the NIEHS site 2020 
Prospective, Same-Day, Direct Comparison of Controlled Attenuation Parameter With the M vs the XL Pr ...   Caussy, Cyrielle; Brissot, Justine; Singh, Seema; Bassirian, Shirin; Hernandez, Carolyn; Betten ... P42ES010337 Clin Gastroenterol Hepatol (2020 Jul) 31843596 Exiting the NIEHS site 2020 
Stem cell regionalization during olfactory bulb neurogenesis depends on regulatory interactions betw ...   Coré, Nathalie; Erni, Andrea; Hoffmann, Hanne M; Mellon, Pamela L; Saurin, Andrew J; Beclin, C ... P42ES010337 Elife (2020 Aug 07) 32762844 Exiting the NIEHS site 2020 
Targeting the renin-angiotensin signaling pathway in COVID-19: Unanswered questions, opportunities, ...   Sriram, Krishna; Loomba, Rohit; Insel, Paul A P42ES010337 Proc Natl Acad Sci U S A (2020 11 24) 33203679 Exiting the NIEHS site 2020 
The Homeodomain Transcription Factors Vax1 and Six6 Are Required for SCN Development and Function.   Pandolfi, Erica C; Breuer, Joseph A; Nguyen Huu, Viet Anh; Talluri, Tulasi; Nguyen, Duong; Lee, ... P42ES010337 Mol Neurobiol (2020 Feb) 31705443 Exiting the NIEHS site 2020 
The Role of Noninvasive Tests for Differentiating NASH From NAFL and Diagnosing Advanced Fibrosis Am ...   Balakrishnan, Maya; Loomba, Rohit P42ES010337 J Clin Gastroenterol (2020 02) 31789757 Exiting the NIEHS site 2020 
Triclosan leads to dysregulation of the metabolic regulator FGF21 exacerbating high fat diet-induced ...   Yueh, Mei-Fei; He, Feng; Chen, Chen; Vu, Catherine; Tripathi, Anupriya; Knight, Rob; Karin, M ... P42ES010337 Proc Natl Acad Sci U S A (2020 12 08) 33229553 Exiting the NIEHS site 2020 
Triptolide targets super-enhancer networks in pancreatic cancer cells and cancer-associated fibrobla ...   Noel, Pawan; Hussein, Shaimaa; Ng, Serina; Antal, Corina E; Lin, Wei; Rodela, Emily; Delgado, ... P42ES010337 Oncogenesis (2020 Nov 09) 33168807 Exiting the NIEHS site 2020 
A gut microbiome signature for cirrhosis due to nonalcoholic fatty liver disease.   Caussy, Cyrielle; Tripathi, Anupriya; Humphrey, Greg; Bassirian, Shirin; Singh, Seema; Faulkner ... P42ES010337 Nat Commun (2019 03 29) 30926798 Exiting the NIEHS site 2019 
A seed resource for screening functionally redundant genes and isolation of new mutants impaired in ...   Hauser, Felix; Ceciliato, Paulo H O; Lin, Yi-Chen; Guo, DanDan; Gregerson, J D; Abbasi, Nazia; ... P42ES010337 J Exp Bot (2019 01 07) 30346611 Exiting the NIEHS site 2019 
Chemical genetic identification of a lectin receptor kinase that transduces immune responses and int ...   Park, Jiyoung; Kim, Tae-Houn; Takahashi, Yohei; Schwab, Rebecca; Dressano, Keini; Stephan, Aar ... P42ES010337 Plant J (2019 May) 30659683 Exiting the NIEHS site 2019 
Choline Uptake and Metabolism Modulate Macrophage IL-1β and IL-18 Production.   Sanchez-Lopez, Elsa; Zhong, Zhenyu; Stubelius, Alexandra; Sweeney, Shannon R; Booshehri, Laela ... P42ES010337 Cell Metab (2019 06 04) 30982734 Exiting the NIEHS site 2019 
Collagen Formation Assessed by N-Terminal Propeptide of Type 3 Procollagen Is a Heritable Trait and ...   Caussy, Cyrielle; Bhargava, Meera; Villesen, Ida F; Gudmann, Natasja S; Leeming, Diana J; Karsd ... P42ES010337 Hepatology (2019 07) 30859582 Exiting the NIEHS site 2019 
Cytogenetic, Genomic, and Functional Characterization of Pituitary Gonadotrope Cell Lines.   Ruf-Zamojski, Frederique; Ge, Yongchao; Pincas, Hanna; Shan, Jidong; Song, Yinghui; Hines, Nik ... P42ES010337 J Endocr Soc (2019 May 01) 31020055 Exiting the NIEHS site 2019 
Deletion of the Homeodomain Protein Six6 From GnRH Neurons Decreases GnRH Gene Expression, Resulting ...   Pandolfi, Erica C; Tonsfeldt, Karen J; Hoffmann, Hanne M; Mellon, Pamela L P42ES010337 Endocrinology (2019 09 01) 31211355 Exiting the NIEHS site 2019 
Differential CRE Expression in Lhrh-cre and GnRH-cre Alleles and the Impact on Fertility in Otx2-Flo ...   Hoffmann, Hanne M; Larder, Rachel; Lee, Jessica S; Hu, Rachael J; Trang, Crystal; Devries, Bro ... P42ES010337 Neuroendocrinology (2019) 30739114 Exiting the NIEHS site 2019 
FXR Regulates Intestinal Cancer Stem Cell Proliferation.   Fu, Ting; Coulter, Sally; Yoshihara, Eiji; Oh, Tae Gyu; Fang, Sungsoon; Cayabyab, Fritz; Zhu, ... P42ES010337 Cell (2019 02 21) 30794774 Exiting the NIEHS site 2019 
Genetic strategies for improving crop yields.   Bailey-Serres, Julia; Parker, Jane E; Ainsworth, Elizabeth A; Oldroyd, Giles E D; Schroeder, Ju ... P42ES010337 Nature (2019 11) 31695205 Exiting the NIEHS site 2019 
Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human ...   Loomba, Rohit; Seguritan, Victor; Li, Weizhong; Long, Tao; Klitgord, Niels; Bhatt, Archana; Du ... P42ES010337 Cell Metab (2019 Sep 03) 31484056 Exiting the NIEHS site 2019 
Haploinsufficiency of Homeodomain Proteins Six3, Vax1, and Otx2 Causes Subfertility in Mice via Dist ...   Hoffmann, Hanne M; Pandolfi, Erica C; Larder, Rachel; Mellon, Pamela L P42ES010337 Neuroendocrinology (2019) 30261489 Exiting the NIEHS site 2019 
Insights into the evolving role of the gut microbiome in nonalcoholic fatty liver disease: rationale ...   Mouzaki, Marialena; Loomba, Rohit P42ES010337 Therap Adv Gastroenterol (2019) 31258623 Exiting the NIEHS site 2019 
Intact leaf gas exchange provides a robust method for measuring the kinetics of stomatal conductance ...   Ceciliato, Paulo H O; Zhang, Jingbo; Liu, Qing; Shen, Xin; Hu, Honghong; Liu, Chen; Schäffner, ... P42ES010337 Plant Methods (2019) 31019545 Exiting the NIEHS site 2019 
NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice.   Liang, Shuang; Ma, Hsiao-Yen; Zhong, Zhenyu; Dhar, Debanjan; Liu, Xiao; Xu, Jun; Koyama, Yuki ... P42ES010337 Gastroenterology (2019 03) 30445007 Exiting the NIEHS site 2019 
Noninvasive Assessment of Liver Disease in Patients With Nonalcoholic Fatty Liver Disease.   Castera, Laurent; Friedrich-Rust, Mireen; Loomba, Rohit P42ES010337 Gastroenterology (2019 04) 30660725 Exiting the NIEHS site 2019 
Preclinical Models for Studying NASH-Driven HCC: How Useful Are They?   Febbraio, Mark A; Reibe, Saskia; Shalapour, Shabnam; Ooi, Geraldine J; Watt, Matthew J; Karin, ... P42ES010337 Cell Metab (2019 01 08) 30449681 Exiting the NIEHS site 2019 
RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype.   Cai, Demin; Wang, Junjian; Gao, Bei; Li, Jin; Wu, Feng; Zou, June X; Xu, Jianzhen; Jiang, Yu ... P42ES010337 Nat Commun (2019 10 11) 31604910 Exiting the NIEHS site 2019 
Standardising the interpretation of liver biopsies in non-alcoholic fatty liver disease clinical tri ...   Pai, Rish K; Kleiner, David E; Hart, John; Adeyi, Oyedele A; Clouston, Andrew D; Behling, Cynt ... P42ES010337 Aliment Pharmacol Ther (2019 11) 31583739 Exiting the NIEHS site 2019 
The 20% Rule of NASH Progression: The Natural History of Advanced Fibrosis and Cirrhosis Caused by N ...   Loomba, Rohit; Adams, Leon A P42ES010337 Hepatology (2019 Dec) 31520407 Exiting the NIEHS site 2019 
The Contribution of the Circadian Gene Bmal1 to Female Fertility and the Generation of the Preovulat ...   Tonsfeldt, Karen J; Schoeller, Erica L; Brusman, Liza E; Cui, Laura J; Lee, Jinkwon; Mellon, P ... P42ES010337 J Endocr Soc (2019 Apr 01) 30906911 Exiting the NIEHS site 2019 
The nuclear receptor REV-ERBα modulates Th17 cell-mediated autoimmune disease.   Chang, Christina; Loo, Chin-San; Zhao, Xuan; Solt, Laura A; Liang, Yuqiong; Bapat, Sagar P; Ch ... P42ES010337 Proc Natl Acad Sci U S A (2019 09 10) 31455731 Exiting the NIEHS site 2019 
The Role of Fibrosis and Liver-Associated Fibroblasts in the Pathogenesis of Hepatocellular Carcinom ...   Baglieri, Jacopo; Brenner, David A; Kisseleva, Tatiana P42ES010337 Int J Mol Sci (2019 Apr 07) 30959975 Exiting the NIEHS site 2019 
YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity.   Wang, Lirui; Mazagova, Magdalena; Pan, Chuyue; Yang, Song; Brandl, Katharina; Liu, Jun; Reilly ... P42ES010337 Proc Natl Acad Sci U S A (2019 Jul 23) 31289229 Exiting the NIEHS site 2019 
A transportome-scale amiRNA-based screen identifies redundant roles of Arabidopsis ABCB6 and ABCB20 ...   Zhang, Yuqin; Nasser, Victoria; Pisanty, Odelia; Omary, Moutasem; Wulff, Nikolai; Di Donato, M ... P42ES010337 Nat Commun (2018 10 11) 30310073 Exiting the NIEHS site 2018 
Abscisic acid-independent stomatal CO2 signal transduction pathway and convergence of CO2 and ABA si ...   Hsu, Po-Kai; Takahashi, Yohei; Munemasa, Shintaro; Merilo, Ebe; Laanemets, Kristiina; Waadt, R ... P42ES010337 Proc Natl Acad Sci U S A (2018 Oct 16) 30282744 Exiting the NIEHS site 2018 
Abscisic acid-induced degradation of Arabidopsis guanine nucleotide exchange factor requires calcium ...   Li, Zixing; Takahashi, Yohei; Scavo, Alexander; Brandt, Benjamin; Nguyen, Desiree; Rieu, Phili ... P42ES010337 Proc Natl Acad Sci U S A (2018 May 08) 29686103 Exiting the NIEHS site 2018 
Antiandrogen Treatment Ameliorates Reproductive and Metabolic Phenotypes in the Letrozole-Induced Mo ...   Ryan, Genevieve E; Malik, Shaddy; Mellon, Pamela L P42ES010337 Endocrinology (2018 04 01) 29471436 Exiting the NIEHS site 2018 
Author Correction: Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity.   Shalapour, Shabnam; Lin, Xue-Jia; Bastian, Ingmar N; Brain, John; Burt, Alastair D; Aksenov, A ... P42ES010337 Nature (2018 09) 29973714 Exiting the NIEHS site 2018 
Chemokines and Chemokine Receptors in the Development of NAFLD.   Roh, Yoon-Seok; Seki, Ekihiro P42ES010337 Adv Exp Med Biol (2018) 29956205 Exiting the NIEHS site 2018 
Cryo-EM Elucidation of the Structure of Bacteriophage P22 Virions after Genome Release.   McNulty, Reginald; Cardone, Giovanni; Gilcrease, Eddie B; Baker, Timothy S; Casjens, Sherwood R ... P42ES010337 Biophys J (2018 03 27) 29590587 Exiting the NIEHS site 2018 
ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P.   Kim, Ju Youn; Garcia-Carbonell, Ricard; Yamachika, Shinichiro; Zhao, Peng; Dhar, Debanjan; Loom ... P42ES010337 Cell (2018 09 20) 30220454 Exiting the NIEHS site 2018 
ERRγ Preserves Brown Fat Innate Thermogenic Activity.   Ahmadian, Maryam; Liu, Sihao; Reilly, Shannon M; Hah, Nasun; Fan, Weiwei; Yoshihara, Eiji; Jha ... P42ES010337 Cell Rep (2018 03 13) 29539415 Exiting the NIEHS site 2018 
ERRγ Promotes Angiogenesis, Mitochondrial Biogenesis, and Oxidative Remodeling in PGC1α/β-Deficient ...   Fan, Weiwei; He, Nanhai; Lin, Chun Shi; Wei, Zong; Hah, Nasun; Waizenegger, Wanda; He, Ming-X ... P42ES010337 Cell Rep (2018 03 06) 29514081 Exiting the NIEHS site 2018 
Geographic Variability in Liver Disease-Related Mortality Rates in the United States.   Desai, Archita P; Mohan, Prashanthinie; Roubal, Anne M; Bettencourt, Ricki; Loomba, Rohit P42ES010337 Am J Med (2018 Jul) 29496501 Exiting the NIEHS site 2018 
Haploinsufficiency of SIX3 Abolishes Male Reproductive Behavior Through Disrupted Olfactory Developm ...   Pandolfi, Erica C; Hoffmann, Hanne M; Schoeller, Erica L; Gorman, Michael R; Mellon, Pamela L P42ES010337 Mol Neurobiol (2018 Nov) 29589282 Exiting the NIEHS site 2018 
Humanized UGT1 Mice, Regulation of UGT1A1, and the Role of the Intestinal Tract in Neonatal Hyperbil ...   Chen, Shujuan; Tukey, Robert H P42ES010337 Drug Metab Dispos (2018 11) 30093417 Exiting the NIEHS site 2018 
IKKα inactivation promotes Kras-initiated lung adenocarcinoma development through disrupting major r ...   Song, Na-Young; Zhu, Feng; Wang, Zining; Willette-Brown, Jami; Xi, Sichuan; Sun, Zhonghe; Su, ... P42ES010337 Proc Natl Acad Sci U S A (2018 01 23) 29311298 Exiting the NIEHS site 2018 
Increased severity of liver fat content and liver fibrosis in non-alcoholic fatty liver disease corr ...   Brouha, Sharon S; Nguyen, Phirum; Bettencourt, Ricki; Sirlin, Claude B; Loomba, Rohit P42ES010337 Eur Radiol (2018 Apr) 29058029 Exiting the NIEHS site 2018 
Integrative genomic analysis of mouse and human hepatocellular carcinoma.   Dow, Michelle; Pyke, Rachel M; Tsui, Brian Y; Alexandrov, Ludmil B; Nakagawa, Hayato; Taniguchi ... P42ES010337 Proc Natl Acad Sci U S A (2018 Oct 16) 30287485 Exiting the NIEHS site 2018 
Link between gut-microbiome derived metabolite and shared gene-effects with hepatic steatosis and fi ...   Caussy, Cyrielle; Hsu, Cynthia; Lo, Min-Tzu; Liu, Amy; Bettencourt, Ricki; Ajmera, Veeral H; B ... P42ES010337 Hepatology (2018 09) 29572891 Exiting the NIEHS site 2018 
Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling.   Dhar, Debanjan; Antonucci, Laura; Nakagawa, Hayato; Kim, Ju Youn; Glitzner, Elisabeth; Caruso, ... P42ES010337 Cancer Cell (2018 06 11) 29894692 Exiting the NIEHS site 2018 
Magnetic Resonance Imaging Proton Density Fat Fraction Associates With Progression of Fibrosis in Pa ...   Ajmera, Veeral; Park, Charlie C; Caussy, Cyrielle; Singh, Seema; Hernandez, Carolyn; Bettencour ... P42ES010337 Gastroenterology (2018 08) 29660324 Exiting the NIEHS site 2018 
Mitogen-activated protein kinases MPK4 and MPK12 are key components mediating CO2 -induced stomatal ...   Tõldsepp, Kadri; Zhang, Jingbo; Takahashi, Yohei; Sindarovska, Yana; Hõrak, Hanna; Ceciliato, ... P42ES010337 Plant J (2018 12) 30203878 Exiting the NIEHS site 2018 
Modulation of the intestinal bile acid/farnesoid X receptor/fibroblast growth factor 15 axis improve ...   Hartmann, Phillipp; Hochrath, Katrin; Horvath, Angela; Chen, Peng; Seebauer, Caroline T; Lloren ... P42ES010337 Hepatology (2018 06) 29159825 Exiting the NIEHS site 2018 
New insights into the pathogenesis and treatment of non-viral hepatocellular carcinoma: a balancing ...   Karin, Michael P42ES010337 Precis Clin Med (2018 Jun) 30687560 Exiting the NIEHS site 2018 
New mitochondrial DNA synthesis enables NLRP3 inflammasome activation.   Zhong, Zhenyu; Liang, Shuang; Sanchez-Lopez, Elsa; He, Feng; Shalapour, Shabnam; Lin, Xue-Jia; ... P42ES010337 Nature (2018 08) 30046112 Exiting the NIEHS site 2018 
Nonalcoholic fatty liver disease, metabolic syndrome, and the fight that will define clinical practi ...   Tapper, Elliot B; Loomba, Rohit P42ES010337 Hepatology (2018 May) 29222913 Exiting the NIEHS site 2018 
Noninvasive imaging biomarker assessment of liver fibrosis by elastography in NAFLD.   Tapper, Elliot B; Loomba, Rohit P42ES010337 Nat Rev Gastroenterol Hepatol (2018 05) 29463906 Exiting the NIEHS site 2018 
Of Mice and Men and Nonalcoholic Steatohepatitis.   Brenner, David A P42ES010337 Hepatology (2018 12) 30033687 Exiting the NIEHS site 2018 
Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice.   Que, Xuchu; Hung, Ming-Yow; Yeang, Calvin; Gonen, Ayelet; Prohaska, Thomas A; Sun, Xiaoli; Die ... P42ES010337 Nature (2018 Jun) 29875409 Exiting the NIEHS site 2018 
Publisher Correction: The gut-liver axis and the intersection with the microbiome.   Tripathi, Anupriya; Debelius, Justine; Brenner, David A; Karin, Michael; Loomba, Rohit; Schnabl ... P42ES010337 Nat Rev Gastroenterol Hepatol (2018 12) 29785003 Exiting the NIEHS site 2018 
Species differences in drug glucuronidation: Humanized UDP-glucuronosyltransferase 1 mice and their ...   Fujiwara, Ryoichi; Yoda, Emiko; Tukey, Robert H P42ES010337 Drug Metab Pharmacokinet (2018 Feb) 29079228 Exiting the NIEHS site 2018 
Tdp1 processes chromate-induced single-strand DNA breaks that collapse replication forks.   Ganguly, Abantika; Guo, Lan; Sun, Lingling; Suo, Fang; Du, Li-Lin; Russell, Paul P42ES010337 PLoS Genet (2018 08) 30148840 Exiting the NIEHS site 2018 
The contribution of toll-like receptor signaling to the development of liver fibrosis and cancer in ...   Song, Isabelle Jingyi; Yang, Yoon Mee; Inokuchi-Shimizu, Sayaka; Roh, Yoon Seok; Yang, Ling; Se ... P42ES010337 Int J Cancer (2018 Jan 01) 28875549 Exiting the NIEHS site 2018 
The gut-liver axis and the intersection with the microbiome.   Tripathi, Anupriya; Debelius, Justine; Brenner, David A; Karin, Michael; Loomba, Rohit; Schnabl ... P42ES010337 Nat Rev Gastroenterol Hepatol (2018 07) 29748586 Exiting the NIEHS site 2018 
Transcriptional interaction between cFOS and the homeodomain-binding transcription factor VAX1 on th ...   Hoffmann, Hanne M; Gong, Ping; Tamrazian, Anika; Mellon, Pamela L P42ES010337 Mol Cell Endocrinol (2018 Feb 05) 28890143 Exiting the NIEHS site 2018 
Vitamin D Switches BAF Complexes to Protect β Cells.   Wei, Zong; Yoshihara, Eiji; He, Nanhai; Hah, Nasun; Fan, Weiwei; Pinto, Antonio F M; Huddy, T ... P42ES010337 Cell (2018 May 17) 29754817 Exiting the NIEHS site 2018 
What Is the Next Frontier in Plant Engineering?   P42ES010337 Cell (2018 Jul 26) 30053421 Exiting the NIEHS site 2018 
A Highly Sensitive Enzymatic Catalysis System for Trace Detection of Arsenic in Water.   Liu, Yuanli; Yu, Chuanbai; Cao, Zhixin; Shvarts, Daniel; Trogler, William C P42ES010337 Chemistry (2017 Aug 01) 28631380 Exiting the NIEHS site 2017 
Assessment of treatment response in non-alcoholic steatohepatitis using advanced magnetic resonance ...   Lin, S C; Heba, E; Bettencourt, R; Lin, G Y; Valasek, M A; Lunde, O; Hamilton, G; Sirlin, C ... P42ES010337 Aliment Pharmacol Ther (2017 Mar) 28116801 Exiting the NIEHS site 2017 
Chromatin status and transcription factor binding to gonadotropin promoters in gonadotrope cell line ...   Xie, Huimin; Hoffmann, Hanne M; Iyer, Anita K; Brayman, Melissa J; Ngo, Cindy; Sunshine, Mary ... P42ES010337 Reprod Biol Endocrinol (2017 Oct 24) 29065928 Exiting the NIEHS site 2017 
Circadian clock cryptochrome proteins regulate autoimmunity.   Cao, Qi; Zhao, Xuan; Bai, Jingwen; Gery, Sigal; Sun, Haibo; Lin, De-Chen; Chen, Qi; Chen, Zh ... P42ES010337 Proc Natl Acad Sci U S A (2017 Nov 21) 29109286 Exiting the NIEHS site 2017 
Crypt Organoid Culture as an in Vitro Model in Drug Metabolism and Cytotoxicity Studies.   Lu, Wenqi; Rettenmeier, Eva; Paszek, Miles; Yueh, Mei-Fei; Tukey, Robert H; Trottier, Jocelyn; ... P42ES010337 Drug Metab Dispos (2017 Jul) 28468837 Exiting the NIEHS site 2017 
Developmental, Genetic, Dietary, and Xenobiotic Influences on Neonatal Hyperbilirubinemia.   Yueh, Mei-Fei; Chen, Shujuan; Nguyen, Nghia; Tukey, Robert H P42ES010337 Mol Pharmacol (2017 May) 28283555 Exiting the NIEHS site 2017 
Erratum to: Stress and the nonsense-mediated RNA decay pathway.   Goetz, Alexandra E; Wilkinson, Miles P42ES010337 Cell Mol Life Sci (2017 11) 28905073 Exiting the NIEHS site 2017 
Erratum: Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity.   Shalapour, Shabnam; Lin, Xue-Jia; Bastian, Ingmar N; Brain, John; Burt, Alastair D; Aksenov, A ... P42ES010337 Nature (2017 Dec 21) 29168501 Exiting the NIEHS site 2017 
Exercise Mimetics: Impact on Health and Performance.   Fan, Weiwei; Evans, Ronald M P42ES010337 Cell Metab (2017 Feb 07) 27889389 Exiting the NIEHS site 2017 
Farnesoid X Receptor an Emerging Target to Combat Obesity.   De Magalhaes Filho, C Daniel; Downes, Michael; Evans, Ronald M P42ES010337 Dig Dis (2017) 28249279 Exiting the NIEHS site 2017 
FGF1 - a new weapon to control type 2 diabetes mellitus.   Gasser, Emanuel; Moutos, Christopher P; Downes, Michael; Evans, Ronald M P42ES010337 Nat Rev Endocrinol (2017 Oct) 28664920 Exiting the NIEHS site 2017 
Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis.   Chung, Hyo Kyun; Ryu, Dongryeol; Kim, Koon Soon; Chang, Joon Young; Kim, Yong Kyung; Yi, Hyon- ... P42ES010337 J Cell Biol (2017 Jan 02) 27986797 Exiting the NIEHS site 2017 
Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human ...   Loomba, Rohit; Seguritan, Victor; Li, Weizhong; Long, Tao; Klitgord, Niels; Bhatt, Archana; Du ... P42ES010337 Cell Metab (2017 May 02) 28467925 Exiting the NIEHS site 2017 
Identification of Novel Fibrosis Modifiers by In Vivo siRNA Silencing.   Vollmann, Elisabeth H; Cao, Lizhi; Amatucci, Aldo; Reynolds, Taylor; Hamann, Stefan; Dalkilic-L ... P42ES010337 Mol Ther Nucleic Acids (2017 Jun 16) 28624207 Exiting the NIEHS site 2017 
Increased Risk of Death, in the Hospital and Outside the Intensive Care Unit, for Patients With Cirr ...   Reinders, Megan E; Wardi, Gabriel; Bettencourt, Ricki; Bouland, Daniel; Bazick, Jessica; Mendle ... P42ES010337 Clin Gastroenterol Hepatol (2017 Nov) 28602970 Exiting the NIEHS site 2017 
Increased risk of mortality by fibrosis stage in nonalcoholic fatty liver disease: Systematic review ...   Dulai, Parambir S; Singh, Siddharth; Patel, Janki; Soni, Meera; Prokop, Larry J; Younossi, Zob ... P42ES010337 Hepatology (2017 May) 28130788 Exiting the NIEHS site 2017 
Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity.   Shalapour, Shabnam; Lin, Xue-Jia; Bastian, Ingmar N; Brain, John; Burt, Alastair D; Aksenov, A ... P42ES010337 Nature (2017 11 16) 29144460 Exiting the NIEHS site 2017 
Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia.   Chen, Shujuan; Lu, Wenqi; Yueh, Mei-Fei; Rettenmeier, Eva; Liu, Miao; Paszek, Miles; Auwerx, ... P42ES010337 Proc Natl Acad Sci U S A (2017 Feb 21) 28167773 Exiting the NIEHS site 2017 
Intestinal PPARδ protects against diet-induced obesity, insulin resistance and dyslipidemia.   Doktorova, Marcela; Zwarts, Irene; Zutphen, Tim van; Dijk, Theo H van; Bloks, Vincent W; Harkem ... P42ES010337 Sci Rep (2017 Apr 12) 28404991 Exiting the NIEHS site 2017 
Isothiocyanates induce UGT1A1 in humanized UGT1 mice in a CAR dependent fashion that is highly depen ...   Yoda, Emiko; Paszek, Miles; Konopnicki, Camille; Fujiwara, Ryoichi; Chen, Shujuan; Tukey, Robe ... P42ES010337 Sci Rep (2017 04 19) 28422158 Exiting the NIEHS site 2017 
Liver inflammation and fibrosis.   Koyama, Yukinori; Brenner, David A P42ES010337 J Clin Invest (2017 Jan 03) 28045404 Exiting the NIEHS site 2017 
Magnetic Resonance Elastography vs Transient Elastography in Detection of Fibrosis and Noninvasive M ...   Park, Charlie C; Nguyen, Phirum; Hernandez, Carolyn; Bettencourt, Ricki; Ramirez, Kimberly; For ... P42ES010337 Gastroenterology (2017 Feb) 27911262 Exiting the NIEHS site 2017 
Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis.   Koyama, Yukinori; Wang, Ping; Liang, Shuang; Iwaisako, Keiko; Liu, Xiao; Xu, Jun; Zhang, Ming ... P42ES010337 J Clin Invest (2017 Apr 03) 28287406 Exiting the NIEHS site 2017 
Metabolic control of regulatory T cell (Treg) survival and function by Lkb1.   He, Nanhai; Fan, Weiwei; Henriquez, Brian; Yu, Ruth T; Atkins, Annette R; Liddle, Christopher; ... P42ES010337 Proc Natl Acad Sci U S A (2017 11 21) 29109251 Exiting the NIEHS site 2017 
Mice with hyperbilirubinemia due to Gilbert's syndrome polymorphism are resistant to hepatic steatos ...   Hinds Jr, Terry D; Hosick, Peter A; Chen, Shujuan; Tukey, Robert H; Hankins, Michael W; Nestor- ... P42ES010337 Am J Physiol Endocrinol Metab (2017 04 01) 28096081 Exiting the NIEHS site 2017 
NCoR1 restrains thymic negative selection by repressing Bim expression to spare thymocytes undergoin ...   Wang, Jianrong; He, Nanhai; Zhang, Na; Quan, Dexian; Zhang, Shuo; Zhang, Caroline; Yu, Ruth T ... P42ES010337 Nat Commun (2017 Oct 16) 29038463 Exiting the NIEHS site 2017 
Nonalcoholic fatty liver disease with cirrhosis increases familial risk for advanced fibrosis.   Caussy, Cyrielle; Soni, Meera; Cui, Jeffrey; Bettencourt, Ricki; Schork, Nicholas; Chen, Chi-H ... P42ES010337 J Clin Invest (2017 Jun 30) 28628033 Exiting the NIEHS site 2017 
PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality contro ...   Dickey, Audrey S; Sanchez, Dafne N; Arreola, Martin; Sampat, Kunal R; Fan, Weiwei; Arbez, Nico ... P42ES010337 Sci Transl Med (2017 Dec 06) 29212711 Exiting the NIEHS site 2017 
PPARδ Promotes Running Endurance by Preserving Glucose.   Fan, Weiwei; Waizenegger, Wanda; Lin, Chun Shi; Sorrentino, Vincenzo; He, Ming-Xiao; Wall, Chr ... P42ES010337 Cell Metab (2017 May 02) 28467934 Exiting the NIEHS site 2017 
Prediction of drug-induced liver injury using keratinocytes.   Hirashima, Rika; Itoh, Tomoo; Tukey, Robert H; Fujiwara, Ryoichi P42ES010337 J Appl Toxicol (2017 Jul) 28138970 Exiting the NIEHS site 2017 
Seeing is believing.   Azoulay-Shemer, Tamar; Hsu, Po-Kai; Schroeder, Julian I P42ES010337 Nat Plants (2017 Oct) 28970562 Exiting the NIEHS site 2017 
Severe Neonatal Hyperbilirubinemia in Crigler-Najjar Syndrome Model Mice Can Be Reversed With Zinc P ...   Fujiwara, Ryoichi; Mitsugi, Ryo; Uemura, Asuka; Itoh, Tomoo; Tukey, Robert H P42ES010337 Hepatol Commun (2017 Oct) 29399656 Exiting the NIEHS site 2017 
Statin Use and Risk of Cirrhosis and Related Complications in Patients With Chronic Liver Diseases: ...   Kim, Rebecca G; Loomba, Rohit; Prokop, Larry J; Singh, Siddharth P42ES010337 Clin Gastroenterol Hepatol (2017 Oct) 28479502 Exiting the NIEHS site 2017 
Stress and the nonsense-mediated RNA decay pathway.   Goetz, Alexandra E; Wilkinson, Miles P42ES010337 Cell Mol Life Sci (2017 10) 28503708 Exiting the NIEHS site 2017 
Stromal cues regulate the pancreatic cancer epigenome and metabolome.   Sherman, Mara H; Yu, Ruth T; Tseng, Tiffany W; Sousa, Cristovao M; Liu, Sihao; Truitt, Morgan ... P42ES010337 Proc Natl Acad Sci U S A (2017 Jan 31) 28096419 Exiting the NIEHS site 2017 
Structural basis for specific ligation of the peroxisome proliferator-activated receptor δ.   Wu, Chyuan-Chuan; Baiga, Thomas J; Downes, Michael; La Clair, James J; Atkins, Annette R; Richa ... P42ES010337 Proc Natl Acad Sci U S A (2017 Mar 28) 28320959 Exiting the NIEHS site 2017 
Synectin promotes fibrogenesis by regulating PDGFR isoforms through distinct mechanisms.   Drinane, Mary C; Yaqoob, Usman; Yu, Haibin; Luo, Fanghong; Greuter, Thomas; Arab, Juan P; Kost ... P42ES010337 JCI Insight (2017 Dec 21) 29263300 Exiting the NIEHS site 2017 
The role of human cytochrome P450 2E1 in liver inflammation and fibrosis.   Xu, Jun; Ma, Hsiao-Yen; Liang, Shuang; Sun, Mengxi; Karin, Gabriel; Koyama, Yukinori; Hu, Ron ... P42ES010337 Hepatol Commun (2017 Dec) 29404441 Exiting the NIEHS site 2017 
TRIF Differentially Regulates Hepatic Steatosis and Inflammation/Fibrosis in Mice.   Yang, Ling; Miura, Kouichi; Zhang, Bi; Matsushita, Hiroshi; Yang, Yoon Mee; Liang, Shuang; Son ... P42ES010337 Cell Mol Gastroenterol Hepatol (2017 May) 28462384 Exiting the NIEHS site 2017 
A Novel Gonadotropin-Releasing Hormone 1 (Gnrh1) Enhancer-Derived Noncoding RNA Regulates Gnrh1 Gene ...   Huang, Polly P; Brusman, Liza E; Iyer, Anita K; Webster, Nicholas J G; Mellon, Pamela L P42ES010337 PLoS One (2016) 27389022 Exiting the NIEHS site 2016 
A small population of hypothalamic neurons govern fertility: the critical role of VAX1 in GnRH neuro ...   Hoffmann, Hanne M; Mellon, Pamela L P42ES010337 Neurosci Commun (Houst) (2016) 28164172 Exiting the NIEHS site 2016 
Acrolein, a New Villain in the Development of Alcoholic Liver Disease.   Seki, Ekihiro P42ES010337 Cell Mol Gastroenterol Hepatol (2016 Sep) 28174735 Exiting the NIEHS site 2016 
Acyl-glucuronide as a Possible Cause of Trovafloxacin-Induced Liver Toxicity: Induction of Chemokine ...   Mitsugi, Ryo; Sumida, Kyohei; Fujie, Yoshiko; Tukey, Robert H; Itoh, Tomoo; Fujiwara, Ryoichi P42ES010337 Biol Pharm Bull (2016) 27725437 Exiting the NIEHS site 2016 
An ABA-increased interaction of the PYL6 ABA receptor with MYC2 Transcription Factor: A putative lin ...   Aleman, Fernando; Yazaki, Junshi; Lee, Melissa; Takahashi, Yohei; Kim, Alice Y; Li, Zixing; Ki ... P42ES010337 Sci Rep (2016 Jun 30) 27357749 Exiting the NIEHS site 2016 
Bmal1 Is Required for Normal Reproductive Behaviors in Male Mice.   Schoeller, Erica L; Clark, Daniel D; Dey, Sandeepa; Cao, Nathan V; Semaan, Sheila J; Chao, Lin ... P42ES010337 Endocrinology (2016 Dec) 27704948 Exiting the NIEHS site 2016 
Cadmium and arsenic override NF-κB developmental regulation of the intestinal UGT1A1 gene and contro ...   Liu, Miao; Chen, Shujuan; Yueh, Mei-Fei; Fujiwara, Ryoichi; Konopnicki, Camille; Hao, Haiping; ... P42ES010337 Biochem Pharmacol (2016 Jun 15) 27060662 Exiting the NIEHS site 2016 
Cistromic and genetic evidence that the vitamin D receptor mediates susceptibility to latitude-depen ...   Booth, D R; Ding, N; Parnell, G P; Shahijanian, F; Coulter, S; Schibeci, S D; Atkins, A R; St ... P42ES010337 Genes Immun (2016 Jun) 26986782 Exiting the NIEHS site 2016 
CO2 Sensing and CO2 Regulation of Stomatal Conductance: Advances and Open Questions.   Engineer, Cawas B; Hashimoto-Sugimoto, Mimi; Negi, Juntaro; Israelsson-Nordström, Maria; Azoulay ... P42ES010337 Trends Plant Sci (2016 Jan) 26482956 Exiting the NIEHS site 2016 
Creating healthy and just bioregions.   Pezzoli, Keith; Leiter, Robert Allen P42ES010337 Rev Environ Health (2016 Mar) 26812849 Exiting the NIEHS site 2016 
Ctp1-dependent clipping and resection of DNA double-strand breaks by Mre11 endonuclease complex are ...   Jensen, Kristi L; Russell, Paul P42ES010337 Nucleic Acids Res (2016 Sep 30) 27325741 Exiting the NIEHS site 2016 
Deletion of Vax1 from Gonadotropin-Releasing Hormone (GnRH) Neurons Abolishes GnRH Expression and Le ...   Hoffmann, Hanne M; Trang, Crystal; Gong, Ping; Kimura, Ikuo; Pandolfi, Erica C; Mellon, Pamela ... P42ES010337 J Neurosci (2016 Mar 23) 27013679 Exiting the NIEHS site 2016 
Effective treatment of steatosis and steatohepatitis by fibroblast growth factor 1 in mouse models o ...   Liu, Weilin; Struik, Dicky; Nies, Vera J M; Jurdzinski, Angelika; Harkema, Liesbeth; de Bruin, ... P42ES010337 Proc Natl Acad Sci U S A (2016 Feb 23) 26858440 Exiting the NIEHS site 2016 
ERRγ Is Required for the Metabolic Maturation of Therapeutically Functional Glucose-Responsive β Cel ...   Yoshihara, Eiji; Wei, Zong; Lin, Chun Shi; Fang, Sungsoon; Ahmadian, Maryam; Kida, Yasuyuki; T ... P42ES010337 Cell Metab (2016 Apr 12) 27076077 Exiting the NIEHS site 2016 
Exosome Migration Inhibitory Factor as a Marker and Therapeutic Target for Pancreatic Cancer.   Matsushita, Hiroshi; Yang, Yoon Mee; Pandol, Stephen J; Seki, Ekihiro P42ES010337 Gastroenterology (2016 Apr) 26922869 Exiting the NIEHS site 2016 
Finding a new role for NEMO: A key player in preventing hepatocyte apoptosis and liver tumorigenesis ...   Hsin, I-Fang; Montano, Erica; Seki, Ekihiro P42ES010337 Hepatology (2016 Jul) 27122117 Exiting the NIEHS site 2016 
Global Fitness Profiling Identifies Arsenic and Cadmium Tolerance Mechanisms in Fission Yeast.   Guo, Lan; Ganguly, Abantika; Sun, Lingling; Suo, Fang; Du, Li-Lin; Russell, Paul P42ES010337 G3 (Bethesda) (2016 Oct 13) 27558664 Exiting the NIEHS site 2016 
Growth and the Environment of Schizosaccharomyces pombe.   Petersen, Janni; Russell, Paul P42ES010337 Cold Spring Harb Protoc (2016 Mar 01) 26933253 Exiting the NIEHS site 2016 
HEDGEHOG Signal in hepatocytes mediates macrophage recruitment: A new mechanism and potential therap ...   Seki, Ekihiro P42ES010337 Hepatology (2016 Apr) 26638191 Exiting the NIEHS site 2016 
Identification of AtOPT4 as a Plant Glutathione Transporter.   Zhang, Zhongchun; Xie, Qingqing; Jobe, Timothy O; Kau, Andrew R; Wang, Cun; Li, Yunxia; Qiu, ... P42ES010337 Mol Plant (2016 Mar 07) 26283048 Exiting the NIEHS site 2016 
Induction of the UDP-Glucuronosyltransferase 1A1 during the Perinatal Period Can Cause Neurodevelopm ...   Hirashima, Rika; Michimae, Hirofumi; Takemoto, Hiroaki; Sasaki, Aya; Kobayashi, Yoshinori; Itoh ... P42ES010337 Mol Pharmacol (2016 Sep) 27413119 Exiting the NIEHS site 2016 
Liver carcinogenesis: from naughty chemicals to soothing fat and the surprising role of NRF2.   Karin, Michael; Dhar, Debanjan P42ES010337 Carcinogenesis (2016 Jun) 27207669 Exiting the NIEHS site 2016 
Mapping transcription factor interactome networks using HaloTag protein arrays.   Yazaki, Junshi; Galli, Mary; Kim, Alice Y; Nito, Kazumasa; Aleman, Fernando; Chang, Katherine ... P42ES010337 Proc Natl Acad Sci U S A (2016 Jul 19) 27357687 Exiting the NIEHS site 2016 
New Developments on the Treatment of Liver Fibrosis.   Koyama, Yukinori; Xu, Jun; Liu, Xiao; Brenner, David A P42ES010337 Dig Dis (2016) 27332862 Exiting the NIEHS site 2016 
NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria.   Zhong, Zhenyu; Umemura, Atsushi; Sanchez-Lopez, Elsa; Liang, Shuang; Shalapour, Shabnam; Wong, ... P42ES010337 Cell (2016 Feb 25) 26919428 Exiting the NIEHS site 2016 
Nitrate-Regulated Glutaredoxins Control Arabidopsis Primary Root Growth.   Patterson, Kurt; Walters, Laura A; Cooper, Andrew M; Olvera, Jocelyn G; Rosas, Miguel A; Rasmus ... P42ES010337 Plant Physiol (2016 Feb) 26662603 Exiting the NIEHS site 2016 
Nonsense-Mediated RNA Decay Influences Human Embryonic Stem Cell Fate.   Lou, Chih-Hong; Chousal, Jennifer; Goetz, Alexandra; Shum, Eleen Y; Brafman, David; Liao, Xiao ... P42ES010337 Stem Cell Reports (2016 06 14) 27304915 Exiting the NIEHS site 2016 
Nuclear receptors and AMPK: can exercise mimetics cure diabetes?   Wall, Christopher E; Yu, Ruth T; Atkins, Anne R; Downes, Michael; Evans, Ronald M P42ES010337 J Mol Endocrinol (2016 Jul) 27106806 Exiting the NIEHS site 2016 
OsHKT1;4-mediated Na(+) transport in stems contributes to Na(+) exclusion from leaf blades of rice a ...   Suzuki, Kei; Yamaji, Naoki; Costa, Alex; Okuma, Eiji; Kobayashi, Natsuko I; Kashiwagi, Tatsuhi ... P42ES010337 BMC Plant Biol (2016 Jan 19) 26786707 Exiting the NIEHS site 2016 
p62 in Cancer: Signaling Adaptor Beyond Autophagy.   Moscat, Jorge; Karin, Michael; Diaz-Meco, Maria T P42ES010337 Cell (2016 Oct 20) 27768885 Exiting the NIEHS site 2016 
p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival ...   Umemura, Atsushi; He, Feng; Taniguchi, Koji; Nakagawa, Hayato; Yamachika, Shinichiro; Font-Burg ... P42ES010337 Cancer Cell (2016 06 13) 27211490 Exiting the NIEHS site 2016 
p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and L ...   Duran, Angeles; Hernandez, Eloy D; Reina-Campos, Miguel; Castilla, Elias A; Subramaniam, Shanka ... P42ES010337 Cancer Cell (2016 Oct 10) 27728806 Exiting the NIEHS site 2016 
p62/SQSTM1-Dr. Jekyll and Mr. Hyde that prevents oxidative stress but promotes liver cancer.   Taniguchi, Koji; Yamachika, Shinichiro; He, Feng; Karin, Michael P42ES010337 FEBS Lett (2016 08) 27404485 Exiting the NIEHS site 2016 
Promising Therapy Candidates for Liver Fibrosis.   Wang, Ping; Koyama, Yukinori; Liu, Xiao; Xu, Jun; Ma, Hsiao-Yen; Liang, Shuang; Kim, In H; Br ... P42ES010337 Front Physiol (2016) 26909046 Exiting the NIEHS site 2016 
Rapid hyperosmotic-induced Ca2+ responses in Arabidopsis thaliana exhibit sensory potentiation and i ...   Stephan, Aaron B; Kunz, Hans-Henning; Yang, Eric; Schroeder, Julian I P42ES010337 Proc Natl Acad Sci U S A (2016 Aug 30) 27528686 Exiting the NIEHS site 2016 
Reconstitution of CO2 Regulation of SLAC1 Anion Channel and Function of CO2-Permeable PIP2;1 Aquapor ...   Wang, Cun; Hu, Honghong; Qin, Xue; Zeise, Brian; Xu, Danyun; Rappel, Wouter-Jan; Boron, Walte ... P42ES010337 Plant Cell (2016 Feb) 26764375 Exiting the NIEHS site 2016 
Reduced Myelination and Increased Glia Reactivity Resulting from Severe Neonatal Hyperbilirubinemia.   Barateiro, Andreia; Chen, Shujuan; Yueh, Mei-Fei; Fernandes, Adelaide; Domingues, Helena Sofia; ... P42ES010337 Mol Pharmacol (2016 Jan) 26480925 Exiting the NIEHS site 2016 
Reduction of p53 by knockdown of the UGT1 locus in colon epithelial cells causes an increase in tumo ...   Liu, Miao; Chen, Shujuan; Yueh, Mei-Fei; Wang, Guangji; Hao, Haiping; Tukey, Robert H P42ES010337 Cell Mol Gastroenterol Hepatol (2016 Jan) 26807433 Exiting the NIEHS site 2016 
Reparative inflammation takes charge of tissue regeneration.   Karin, Michael; Clevers, Hans P42ES010337 Nature (2016 Jan 21) 26791721 Exiting the NIEHS site 2016 
Sestrin regulation of TORC1: Is Sestrin a leucine sensor?   Lee, Jun Hee; Cho, Uhn-Soo; Karin, Michael P42ES010337 Sci Signal (2016 Jun 07) 27273098 Exiting the NIEHS site 2016 
Stage-specific regulation of the WNT/β-catenin pathway enhances differentiation of hESCs into hepato ...   Touboul, Thomas; Chen, Shujuan; To, Cuong C; Mora-Castilla, Sergio; Sabatini, Karen; Tukey, Ro ... P42ES010337 J Hepatol (2016 Jun) 26921690 Exiting the NIEHS site 2016 
The Role of NADPH Oxidases (NOXs) in Liver Fibrosis and the Activation of Myofibroblasts.   Liang, Shuang; Kisseleva, Tatiana; Brenner, David A P42ES010337 Front Physiol (2016) 26869935 Exiting the NIEHS site 2016 
The Transmembrane Region of Guard Cell SLAC1 Channels Perceives CO2 Signals via an ABA-Independent P ...   Yamamoto, Yoshiko; Negi, Juntaro; Wang, Cun; Isogai, Yasuhiro; Schroeder, Julian I; Iba, Koh P42ES010337 Plant Cell (2016 Feb) 26764376 Exiting the NIEHS site 2016 
Triclosan: A Widespread Environmental Toxicant with Many Biological Effects.   Yueh, Mei-Fei; Tukey, Robert H P42ES010337 Annu Rev Pharmacol Toxicol (2016) 26738475 Exiting the NIEHS site 2016 
A Novel Letrozole Model Recapitulates Both the Reproductive and Metabolic Phenotypes of Polycystic O ...   Kauffman, Alexander S; Thackray, Varykina G; Ryan, Genevieve E; Tolson, Kristen P; Glidewell-Ken ... P42ES010337 Biol Reprod (2015 Sep) 26203175 Exiting the NIEHS site 2015 
Abscisic acid and other plant hormones: Methods to visualize distribution and signaling.   Waadt, Rainer; Hsu, Po-Kai; Schroeder, Julian I P42ES010337 Bioessays (2015 Dec) 26577078 Exiting the NIEHS site 2015 
Absent Progesterone Signaling in Kisspeptin Neurons Disrupts the LH Surge and Impairs Fertility in F ...   Stephens, Shannon B Z; Tolson, Kristen P; Rouse Jr, Melvin L; Poling, Matthew C; Hashimoto-Party ... P42ES010337 Endocrinology (2015 Sep) 26076042 Exiting the NIEHS site 2015 
Aging and liver disease.   Kim, In Hee; Kisseleva, Tatiana; Brenner, David A P42ES010337 Curr Opin Gastroenterol (2015 May) 25850346 Exiting the NIEHS site 2015 
Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER s ...   Antonucci, Laura; Fagman, Johan B; Kim, Ju Youn; Todoric, Jelena; Gukovsky, Ilya; Mackey, Maso ... P42ES010337 Proc Natl Acad Sci U S A (2015 Nov 10) 26512112 Exiting the NIEHS site 2015 
BRD4 is a novel therapeutic target for liver fibrosis.   Ding, Ning; Hah, Nasun; Yu, Ruth T; Sherman, Mara H; Benner, Chris; Leblanc, Mathias; He, Min ... P42ES010337 Proc Natl Acad Sci U S A (2015 Dec 22) 26644586 Exiting the NIEHS site 2015 
Calcipotriol Targets LRP6 to Inhibit Wnt Signaling in Pancreatic Cancer.   Arensman, Michael D; Nguyen, Phillip; Kershaw, Kathleen M; Lay, Anna R; Ostertag-Hill, Claire A ... P42ES010337 Mol Cancer Res (2015 Nov) 26224368 Exiting the NIEHS site 2015 
Calcium specificity signaling mechanisms in abscisic acid signal transduction in Arabidopsis guard c ...   Brandt, Benjamin; Munemasa, Shintaro; Wang, Cun; Nguyen, Desiree; Yong, Taiming; Yang, Paul G; ... P42ES010337 Elife (2015 Jul 20) 26192964 Exiting the NIEHS site 2015 
Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice.   Mazagova, Magdalena; Wang, Lirui; Anfora, Andrew T; Wissmueller, Max; Lesley, Scott A; Miyamoto ... P42ES010337 FASEB J (2015 Mar) 25466902 Exiting the NIEHS site 2015 
Comment on 'Fluorescence sensing of arsenate at nanomolar level in a greener way: naphthalene based ...   Liu, Yuanli; Trogler, William C P42ES010337 Chem Commun (Camb) (2015 Oct 11) 26299989 Exiting the NIEHS site 2015 
Corrigendum: Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer.   Suh, Jae Myoung; Jonker, Johan W; Ahmadian, Maryam; Goetz, Regina; Lackey, Denise; Osborn, Oli ... P42ES010337 Nature (2015 Apr 16) 25739500 Exiting the NIEHS site 2015 
Critical Function of γH2A in S-Phase.   Mejia-Ramirez, Eva; Limbo, Oliver; Langerak, Petra; Russell, Paul P42ES010337 PLoS Genet (2015 Sep) 26368543 Exiting the NIEHS site 2015 
Deficiency of NOX1 or NOX4 Prevents Liver Inflammation and Fibrosis in Mice through Inhibition of He ...   Lan, Tian; Kisseleva, Tatiana; Brenner, David A P42ES010337 PLoS One (2015) 26222337 Exiting the NIEHS site 2015 
Depletion of fat-resident Treg cells prevents age-associated insulin resistance.   Bapat, Sagar P; Myoung Suh, Jae; Fang, Sungsoon; Liu, Sihao; Zhang, Yang; Cheng, Albert; Zhou, ... P42ES010337 Nature (2015 Dec 03) 26580014 Exiting the NIEHS site 2015 
Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular car ...   Finkin, Shlomi; Yuan, Detian; Stein, Ilan; Taniguchi, Koji; Weber, Achim; Unger, Kristian; Bro ... P42ES010337 Nat Immunol (2015 Dec) 26502405 Exiting the NIEHS site 2015 
Effect of weight loss on magnetic resonance imaging estimation of liver fat and volume in patients w ...   Patel, Niraj S; Doycheva, Iliana; Peterson, Michael R; Hooker, Jonathan; Kisselva, Tatiana; Sch ... P42ES010337 Clin Gastroenterol Hepatol (2015 Mar) 25218667 Exiting the NIEHS site 2015 
Expression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Su ...   Kutsuno, Yuki; Hirashima, Rika; Sakamoto, Masaya; Ushikubo, Hiroko; Michimae, Hirofumi; Itoh, ... P42ES010337 Drug Metab Dispos (2015 Jul) 25953521 Exiting the NIEHS site 2015 
Genetic Interaction Landscape Reveals Critical Requirements for Schizosaccharomyces pombe Brc1 in DN ...   Sánchez, Arancha; Roguev, Assen; Krogan, Nevan J; Russell, Paul P42ES010337 G3 (Bethesda) (2015 Mar 19) 25795664 Exiting the NIEHS site 2015 
Guard cell photosynthesis is critical for stomatal turgor production, yet does not directly mediate ...   Azoulay-Shemer, Tamar; Palomares, Axxell; Bagheri, Andisheh; Israelsson-Nordstrom, Maria; Engine ... P42ES010337 Plant J (2015 Aug) 26096271 Exiting the NIEHS site 2015 
Hepatic inflammation and fibrosis: functional links and key pathways.   Seki, Ekihiro; Schwabe, Robert F P42ES010337 Hepatology (2015 Mar) 25066777 Exiting the NIEHS site 2015 
Homeodomain Proteins SIX3 and SIX6 Regulate Gonadotrope-specific Genes During Pituitary Development.   Xie, Huimin; Hoffmann, Hanne M; Meadows, Jason D; Mayo, Susan L; Trang, Crystal; Leming, Sunam ... P42ES010337 Mol Endocrinol (2015 Jun) 25915183 Exiting the NIEHS site 2015 
Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer.   Font-Burgada, Joan; Shalapour, Shabnam; Ramaswamy, Suvasini; Hsueh, Brian; Rossell, David; Umem ... P42ES010337 Cell (2015 Aug 13) 26276631 Exiting the NIEHS site 2015 
Imaging Fibrosis and Separating Collagens using Second Harmonic Generation and Phasor Approach to Fl ...   Ranjit, Suman; Dvornikov, Alexander; Stakic, Milka; Hong, Suk-Hyun; Levi, Moshe; Evans, Ronald ... P42ES010337 Sci Rep (2015 Aug 21) 26293987 Exiting the NIEHS site 2015 
Inflammation-sensitive super enhancers form domains of coordinately regulated enhancer RNAs.   Hah, Nasun; Benner, Chris; Chong, Ling-Wa; Yu, Ruth T; Downes, Michael; Evans, Ronald M P42ES010337 Proc Natl Acad Sci U S A (2015 Jan 20) 25564661 Exiting the NIEHS site 2015 
Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance.   Fang, Sungsoon; Suh, Jae Myoung; Reilly, Shannon M; Yu, Elizabeth; Osborn, Olivia; Lackey, Den ... P42ES010337 Nat Med (2015 Feb) 25559344 Exiting the NIEHS site 2015 
Live Cell Imaging with R-GECO1 Sheds Light on flg22- and Chitin-Induced Transient [Ca(2+)]cyt Patter ...   Keinath, Nana F; Waadt, Rainer; Brugman, Rik; Schroeder, Julian I; Grossmann, Guido; Schumacher ... P42ES010337 Mol Plant (2015 Aug) 26002145 Exiting the NIEHS site 2015 
MafG, A Novel Target of FXR that Regulates Bile Acid Homeostasis.   Yang, Yoon Mee; Roh, Yoon Seok; Seki, Ekihiro P42ES010337 Gastroenterology (2015 Dec) 26501563 Exiting the NIEHS site 2015 
Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to ...   Bourne, Yves; Sulzenbacher, Gerlind; Radić, Zoran; Aráoz, Rómulo; Reynaud, Morgane; Benoit, Ev ... P42ES010337 Structure (2015 Jun 02) 26004441 Exiting the NIEHS site 2015 
Mechanisms of abscisic acid-mediated control of stomatal aperture.   Munemasa, Shintaro; Hauser, Felix; Park, Jiyoung; Waadt, Rainer; Brandt, Benjamin; Schroeder, ... P42ES010337 Curr Opin Plant Biol (2015 Dec) 26599955 Exiting the NIEHS site 2015 
New therapies for hepatic fibrosis.   Koyama, Yukinori; Brenner, David A P42ES010337 Clin Res Hepatol Gastroenterol (2015 Sep) 26206573 Exiting the NIEHS site 2015 
Nicotine regulates the expression of UDP-glucuronosyltransferase (UGT) in humanized UGT1 mouse brain ...   Sakamoto, Masaya; Itoh, Tomoo; Tukey, Robert H; Fujiwara, Ryoichi P42ES010337 Drug Metab Pharmacokinet (2015 Aug) 26210671 Exiting the NIEHS site 2015 
P16INK4a Upregulation Mediated by SIX6 Defines Retinal Ganglion Cell Pathogenesis in Glaucoma.   Skowronska-Krawczyk, Dorota; Zhao, Ling; Zhu, Jie; Weinreb, Robert N; Cao, Guiqun; Luo, Jing; ... P42ES010337 Mol Cell (2015 Sep 17) 26365380 Exiting the NIEHS site 2015 
PPARs and ERRs: molecular mediators of mitochondrial metabolism.   Fan, Weiwei; Evans, Ronald P42ES010337 Curr Opin Cell Biol (2015 Apr) 25486445 Exiting the NIEHS site 2015 
Recent advancement of molecular mechanisms of liver fibrosis.   Seki, Ekihiro; Brenner, David A P42ES010337 J Hepatobiliary Pancreat Sci (2015 Jul) 25869468 Exiting the NIEHS site 2015 
Role of extrahepatic UDP-glucuronosyltransferase 1A1: Advances in understanding breast milk-induced ...   Fujiwara, Ryoichi; Maruo, Yoshihiro; Chen, Shujuan; Tukey, Robert H P42ES010337 Toxicol Appl Pharmacol (2015 Nov 15) 26342858 Exiting the NIEHS site 2015 
Role of Gut Microbiota in Liver Disease.   Brenner, David A; Paik, Yong-Han; Schnabl, Bernd P42ES010337 J Clin Gastroenterol (2015) 26447960 Exiting the NIEHS site 2015 
The NIEHS Superfund Research Program: 25 Years of Translational Research for Public Health.   Landrigan, Philip J; Wright, Robert O; Cordero, Jose F; Eaton, David L; Goldstein, Bernard D; H ... P42ES004940, P42ES010337, P42ES017198 Environ Health Perspect (2015 Oct) 25978799 Exiting the NIEHS site 2015 
The TM6SF2 variants, novel genetic predictors for nonalcoholic steatohepatitis.   Roh, Yoon-Seok; Loomba, Rohit; Seki, Ekihiro P42ES010337 Gastroenterology (2015 Jan) 25451657 Exiting the NIEHS site 2015 
TNFα in liver fibrosis.   Yang, Yoon Mee; Seki, Ekihiro P42ES010337 Curr Pathobiol Rep (2015 Dec) 26726307 Exiting the NIEHS site 2015 
A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic ...   Moles, Anna; Murphy, Lindsay; Wilson, Caroline L; Chakraborty, Jayashree Bagchi; Fox, Christoph ... P42ES010337 J Hepatol (2014 Apr) 24333183 Exiting the NIEHS site 2014 
Bilirubin uridine diphosphate-glucuronosyltransferase variation is a genetic basis of breast milk ja ...   Maruo, Yoshihiro; Morioka, Yoriko; Fujito, Hiroshi; Nakahara, Sayuri; Yanagi, Takahide; Matsui, ... P42ES010337 J Pediatr (2014 Jul) 24650397 Exiting the NIEHS site 2014 
Carbonic anhydrases, EPF2 and a novel protease mediate CO2 control of stomatal development.   Engineer, Cawas B; Ghassemian, Majid; Anderson, Jeffrey C; Peck, Scott C; Hu, Honghong; Schroed ... P42ES010337 Nature (2014 Sep 11) 25043023 Exiting the NIEHS site 2014 
Cerium oxide nanoparticles protect against Aβ-induced mitochondrial fragmentation and neuronal cell ...   Dowding, J M; Song, W; Bossy, K; Karakoti, A; Kumar, A; Kim, A; Bossy, B; Seal, S; Ellisman, ... P42ES010337 Cell Death Differ (2014 Oct) 24902900 Exiting the NIEHS site 2014 
Developmental onset of bilirubin-induced neurotoxicity involves Toll-like receptor 2-dependent signa ...   Yueh, Mei-Fei; Chen, Shujuan; Nguyen, Nghia; Tukey, Robert H P42ES010337 J Biol Chem (2014 Feb 21) 24403077 Exiting the NIEHS site 2014 
Differences in health symptoms among residents living near illegal dump sites in Los Laureles Canyon ...   Al-Delaimy, Wael K; Larsen, Catherine Wood; Pezzoli, Keith P42ES010337 Int J Environ Res Public Health (2014 Sep) 25226411 Exiting the NIEHS site 2014 
Effects of exogenous pyoverdines on Fe availability and their impacts on Mn(II) oxidation by Pseudom ...   Lee, Sung-Woo; Parker, Dorothy L; Geszvain, Kati; Tebo, Bradley M P42ES010337 Front Microbiol (2014) 25009534 Exiting the NIEHS site 2014 
Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer.   Suh, Jae Myoung; Jonker, Johan W; Ahmadian, Maryam; Goetz, Regina; Lackey, Denise; Osborn, Oli ... P42ES010337 Nature (2014 Sep 18) 25043058 Exiting the NIEHS site 2014 
ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development.   Nakagawa, Hayato; Umemura, Atsushi; Taniguchi, Koji; Font-Burgada, Joan; Dhar, Debanjan; Ogata, ... P42ES010337 Cancer Cell (2014 Sep 08) 25132496 Exiting the NIEHS site 2014 
FRET-based reporters for the direct visualization of abscisic acid concentration changes and distrib ...   Waadt, Rainer; Hitomi, Kenichi; Nishimura, Noriyuki; Hitomi, Chiharu; Adams, Stephen R; Getzoff ... P42ES010337 Elife (2014) 24737861 Exiting the NIEHS site 2014 
GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis.   Lopez-Sanchez, Inmaculada; Dunkel, Ying; Roh, Yoon-Seok; Mittal, Yash; De Minicis, Samuele; Mur ... P42ES010337 Nat Commun (2014 Jul 21) 25043713 Exiting the NIEHS site 2014 
Glucose induces intestinal human UDP-glucuronosyltransferase (UGT) 1A1 to prevent neonatal hyperbili ...   Aoshima, Naoya; Fujie, Yoshiko; Itoh, Tomoo; Tukey, Robert H; Fujiwara, Ryoichi P42ES010337 Sci Rep (2014) 25209391 Exiting the NIEHS site 2014 
Glucuronidation of drugs and drug-induced toxicity in humanized UDP-glucuronosyltransferase 1 mice.   Kutsuno, Yuki; Itoh, Tomoo; Tukey, Robert H; Fujiwara, Ryoichi P42ES010337 Drug Metab Dispos (2014 Jul) 24764149 Exiting the NIEHS site 2014 
Heterozygous deletion of ventral anterior homeobox (vax1) causes subfertility in mice.   Hoffmann, Hanne M; Tamrazian, Anika; Xie, Huimin; Pérez-Millán, María Inés; Kauffman, Alexander ... P42ES010337 Endocrinology (2014 Oct) 25060364 Exiting the NIEHS site 2014 
Influence of stress-induced intermediates on gonadotropin gene expression in gonadotrope cells.   Breen, Kellie M; Mellon, Pamela L P42ES010337 Mol Cell Endocrinol (2014 Mar 25) 24012628 Exiting the NIEHS site 2014 
Interactions between the intestinal microbiome and liver diseases.   Schnabl, Bernd; Brenner, David A P42ES010337 Gastroenterology (2014 May) 24440671 Exiting the NIEHS site 2014 
KISS1R signals independently of Gαq/11 and triggers LH secretion via the β-arrestin pathway in the m ...   Ahow, Maryse; Min, Le; Pampillo, Macarena; Nash, Connor; Wen, Junping; Soltis, Kathleen; Carro ... P42ES010337 Endocrinology (2014 Nov) 25147978 Exiting the NIEHS site 2014 
Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition.   Umemura, Atsushi; Park, Eek Joong; Taniguchi, Koji; Lee, Jun Hee; Shalapour, Shabnam; Valasek, ... P42ES010337 Cell Metab (2014 Jul 01) 24910242 Exiting the NIEHS site 2014 
Mechanisms of vascular dysfunction in mice with endothelium-specific deletion of the PPAR-δ gene.   d'Uscio, Livius V; He, Tongrong; Santhanam, Anantha Vijay R; Tai, Li-Jung; Evans, Ronald M; Kat ... P42ES010337 Am J Physiol Heart Circ Physiol (2014 Apr 01) 24486511 Exiting the NIEHS site 2014 
Microbiome-obesity-liver cancer interaction: senescence of hepatic stellate cells and bile acids pla ...   Seki, Ekihiro P42ES010337 Gastroenterology (2014 Mar) 24468171 Exiting the NIEHS site 2014 
NCOA5, IL-6, type 2 diabetes, and HCC: The deadly quartet.   Dhar, Debanjan; Seki, Ekihiro; Karin, Michael P42ES010337 Cell Metab (2014 Jan 07) 24411937 Exiting the NIEHS site 2014 
Neurokinin B induces c-fos transcription via protein kinase C and activation of serum response facto ...   Glidewell-Kenney, Christine A; Trang, Crystal; Shao, Paul P; Gutierrez-Reed, Navarre; Uzo-Okerek ... P42ES010337 Endocrinology (2014 Oct) 25057795 Exiting the NIEHS site 2014 
Novel fate-tracing strategies show that hepatic stellate cells mediate fibrosis in vivo.   Liang, Shuang; Zhong, Zhenyu; Seki, Ekihiro P42ES010337 Gastroenterology (2014 Jun) 24768331 Exiting the NIEHS site 2014 
Nrf2 activation protects the liver from ischemia/reperfusion injury in mice.   Kudoh, Kazuhiro; Uchinami, Hiroshi; Yoshioka, Masato; Seki, Ekihiro; Yamamoto, Yuzo P42ES010337 Ann Surg (2014 Jul) 24368646 Exiting the NIEHS site 2014 
Nuclear receptors and metabolism: from feast to famine.   Hong, Suk-Hyun; Ahmadian, Maryam; Yu, Ruth T; Atkins, Annette R; Downes, Michael; Evans, Ronal ... P42ES010337 Diabetologia (2014 May) 24619218 Exiting the NIEHS site 2014 
Nuclear receptors rock around the clock.   Zhao, Xuan; Cho, Han; Yu, Ruth T; Atkins, Annette R; Downes, Michael; Evans, Ronald M P42ES010337 EMBO Rep (2014 May) 24737872 Exiting the NIEHS site 2014 
Nuclear Receptors, RXR, and the Big Bang.   Evans, Ronald M; Mangelsdorf, David J P42ES010337 Cell (2014 Mar 27) 24679540 Exiting the NIEHS site 2014 
One Bioregion/One Health: An Integrative Narrative for Transboundary Planning along the US-Mexico Bo ...   Pezzoli, Keith; Kozo, Justine; Ferran, Karen; Wooten, Wilma; Gomez, Gudelia Rangel; Al-Delaimy, ... P42ES010337 Glob Soc (2014) 26097402 Exiting the NIEHS site 2014 
OPT3 is a component of the iron-signaling network between leaves and roots and misregulation of OPT3 ...   Mendoza-Cózatl, David G; Xie, Qingqing; Akmakjian, Garo Z; Jobe, Timothy O; Patel, Ami; Stacey, ... P42ES010337 Mol Plant (2014 Sep) 24880337 Exiting the NIEHS site 2014 
Phytochelatin-metal(loid) transport into vacuoles shows different substrate preferences in barley an ...   Song, Won-Yong; Mendoza-Cózatl, David G; Lee, Youngsook; Schroeder, Julian I; Ahn, Sang-Nag; Le ... P42ES010337 Plant Cell Environ (2014 May) 24313707 Exiting the NIEHS site 2014 
Plant salt stress status is transmitted systemically via propagating calcium waves.   Stephan, Aaron B; Schroeder, Julian I P42ES010337 Proc Natl Acad Sci U S A (2014 Apr 29) 24737890 Exiting the NIEHS site 2014 
Plant salt-tolerance mechanisms.   Deinlein, Ulrich; Stephan, Aaron B; Horie, Tomoaki; Luo, Wei; Xu, Guohua; Schroeder, Julian I P42ES010337 Trends Plant Sci (2014 Jun) 24630845 Exiting the NIEHS site 2014 
Plastidial transporters KEA1, -2, and -3 are essential for chloroplast osmoregulation, integrity, an ...   Kunz, Hans-Henning; Gierth, Markus; Herdean, Andrei; Satoh-Cruz, Mio; Kramer, David M; Spetea, ... P42ES010337 Proc Natl Acad Sci U S A (2014 May 20) 24794527 Exiting the NIEHS site 2014 
Pyoverdine synthesis by the Mn(II)-oxidizing bacterium Pseudomonas putida GB-1.   Parker, Dorothy L; Lee, Sung-Woo; Geszvain, Kati; Davis, Richard E; Gruffaz, Christelle; Meyer, ... P42ES010337 Front Microbiol (2014) 24847318 Exiting the NIEHS site 2014 
Regulation of the Rhp26ERCC6/CSB chromatin remodeler by a novel conserved leucine latch motif.   Wang, Lanfeng; Limbo, Oliver; Fei, Jia; Chen, Lu; Kim, Bong; Luo, Jie; Chong, Jenny; Conaway, ... P42ES010337 Proc Natl Acad Sci U S A (2014 Dec 30) 25512493 Exiting the NIEHS site 2014 
Role of NADPH oxidases in liver fibrosis.   Paik, Yong-Han; Kim, Jonghwa; Aoyama, Tomonori; De Minicis, Samuele; Bataller, Ramon; Brenner, ... P42ES010337 Antioxid Redox Signal (2014 Jun 10) 24040957 Exiting the NIEHS site 2014 
Roles of binding elements, FOXL2 domains, and interactions with cJUN and SMADs in regulation of FSHβ ...   Roybal, Lacey L; Hambarchyan, Arpi; Meadows, Jason D; Barakat, Nermeen H; Pepa, Patricia A; Bre ... P42ES010337 Mol Endocrinol (2014 Oct) 25105693 Exiting the NIEHS site 2014 
Self-assembled Targeting of Cancer Cells by Iron(III)-doped, Silica Nanoparticles.   Mitchell, K K Pohaku; Sandoval, S; Cortes-Mateos, M J; Alfaro, J G; Kummel, A C; Trogler, W C P42ES010337 J Mater Chem B (2014 Dec 07) 25364507 Exiting the NIEHS site 2014 
Sestrins inhibit mTORC1 kinase activation through the GATOR complex.   Parmigiani, Anita; Nourbakhsh, Aida; Ding, Boxiao; Wang, Wei; Kim, Young Chul; Akopiants, Kons ... P42ES010337 Cell Rep (2014 Nov 20) 25457612 Exiting the NIEHS site 2014 
Synthesis and surface functionalization of silica nanoparticles for nanomedicine.   Liberman, Alexander; Mendez, Natalie; Trogler, William C; Kummel, Andrew C P42ES010337 Surf Sci Rep (2014 Sep) 25364083 Exiting the NIEHS site 2014 
TAK1 regulates hepatic cell survival and carcinogenesis.   Roh, Yoon Seok; Song, Jingyi; Seki, Ekihiro P42ES010337 J Gastroenterol (2014 Feb) 24443058 Exiting the NIEHS site 2014 
TAK1-dependent autophagy: A suppressor of fatty liver disease and hepatic oncogenesis.   Seki, Ekihiro P42ES010337 Mol Cell Oncol (2014) 26709386 Exiting the NIEHS site 2014 
TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis.   Inokuchi-Shimizu, Sayaka; Park, Eek Joong; Roh, Yoon Seok; Yang, Ling; Zhang, Bi; Song, Jingyi ... P42ES010337 J Clin Invest (2014 Aug) 24983318 Exiting the NIEHS site 2014 
The commonly used antimicrobial additive triclosan is a liver tumor promoter.   Yueh, Mei-Fei; Taniguchi, Koji; Chen, Shujuan; Evans, Ronald M; Hammock, Bruce D; Karin, Micha ... P42ES004699, P42ES010337 Proc Natl Acad Sci U S A (2014 Dec 02) 25404284 Exiting the NIEHS site 2014 
Toll-like receptor 7-mediated type I interferon signaling prevents cholestasis- and hepatotoxin-indu ...   Roh, Yoon Seok; Park, Surim; Kim, Jong Won; Lim, Chae Woong; Seki, Ekihiro; Kim, Bumseok P42ES010337 Hepatology (2014 Jul) 24375615 Exiting the NIEHS site 2014 
Transcriptional repression of the transforming growth factor β (TGF-β) Pseudoreceptor BMP and activi ...   Liu, Cheng; Chen, Xiaorong; Yang, Ling; Kisseleva, Tatiana; Brenner, David A; Seki, Ekihiro P42ES010337 J Biol Chem (2014 Mar 07) 24448807 Exiting the NIEHS site 2014 
Transforming growth factor beta signaling in hepatocytes participates in steatohepatitis through reg ...   Yang, Ling; Roh, Yoon Seok; Song, Jingyi; Zhang, Bi; Liu, Cheng; Loomba, Rohit; Seki, Ekihiro P42ES010337 Hepatology (2014 Feb) 23996730 Exiting the NIEHS site 2014 
Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic ca ...   Sherman, Mara H; Yu, Ruth T; Engle, Dannielle D; Ding, Ning; Atkins, Annette R; Tiriac, Herve; ... P42ES010337 Cell (2014 Sep 25) 25259922 Exiting the NIEHS site 2014 
A genomic-scale artificial microRNA library as a tool to investigate the functionally redundant gene ...   Hauser, Felix; Chen, Wenxiao; Deinlein, Ulrich; Chang, Kenneth; Ossowski, Stephan; Fitz, Joffr ... P42ES010337 Plant Cell (2013 Aug) 23956262 Exiting the NIEHS site 2013 
A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response.   Ding, Ning; Yu, Ruth T; Subramaniam, Nanthakumar; Sherman, Mara H; Wilson, Caroline; Rao, Renu ... P42ES010337 Cell (2013 Apr 25) 23622244 Exiting the NIEHS site 2013 
Aberrant development of the suprachiasmatic nucleus and circadian rhythms in mice lacking the homeod ...   Clark, Daniel D; Gorman, Michael R; Hatori, Megumi; Meadows, Jason D; Panda, Satchidananda; Mel ... P42ES010337 J Biol Rhythms (2013 Feb) 23382588 Exiting the NIEHS site 2013 
DIDS (4,4-diisothiocyanatostilbenedisulphonic acid) induces apoptotic cell death in a hippocampal ne ...   Pamenter, Matthew E; Perkins, Guy A; Gu, Xiang Q; Ellisman, Mark H; Haddad, Gabriel G P42ES010337 PLoS One (2013) 23577164 Exiting the NIEHS site 2013 
Elemental concentrations in the seed of mutants and natural variants of Arabidopsis thaliana grown u ...   McDowell, Stephen C; Akmakjian, Garo; Sladek, Chris; Mendoza-Cozatl, David; Morrissey, Joe B; S ... P42ES010337 PLoS One (2013) 23671651 Exiting the NIEHS site 2013 
Elimination of manganese(II,III) oxidation in Pseudomonas putida GB-1 by a double knockout of two pu ...   Geszvain, Kati; McCarthy, James K; Tebo, Bradley M P42ES010337 Appl Environ Microbiol (2013 Jan) 23124227 Exiting the NIEHS site 2013 
Evaluation of UGT protein interactions in human hepatocytes: effect of siRNA down regulation of UGT1 ...   Konopnicki, Camille M; Dickmann, Leslie J; Tracy, Jeffrey M; Tukey, Robert H; Wienkers, Larry C ... P42ES010337 Arch Biochem Biophys (2013 Jul 15) 23562620 Exiting the NIEHS site 2013 
Evidence for orphan nuclear receptor TR4 in the etiology of Cushing disease.   Du, Li; Bergsneider, Marvin; Mirsadraei, Leili; Young, Steven H; Jonker, Johan W; Downes, Mich ... P42ES010337 Proc Natl Acad Sci U S A (2013 May 21) 23653479 Exiting the NIEHS site 2013 
Gene dosage of Otx2 is important for fertility in male mice.   Larder, Rachel; Kimura, Ikuo; Meadows, Jason; Clark, Daniel D; Mayo, Susan; Mellon, Pamela L P42ES010337 Mol Cell Endocrinol (2013 Sep 05) 23811236 Exiting the NIEHS site 2013 
Hepatic actions of vitamin D receptor ligands: a sunshine option for chronic liver disease?   Ding, Ning; Liddle, Christopher; Evans, Ronald M; Downes, Michael P42ES010337 Expert Rev Clin Pharmacol (2013 Nov) 24164608 Exiting the NIEHS site 2013 
Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 sig ...   He, Guobin; Dhar, Debanjan; Nakagawa, Hayato; Font-Burgada, Joan; Ogata, Hisanobu; Jiang, Yuho ... P42ES010337 Cell (2013 Oct 10) 24120137 Exiting the NIEHS site 2013 
Identification of three novel natural product compounds that activate PXR and CAR and inhibit inflam ...   Kittayaruksakul, Suticha; Zhao, Wenchen; Xu, Meishu; Ren, Songrong; Lu, Jing; Wang, Ju; Downes ... P42ES010337 Pharm Res (2013 Sep) 23896737 Exiting the NIEHS site 2013 
Impact of fatty acids on human UDP-glucuronosyltransferase 1A1 activity and its expression in neonat ...   Shibuya, Ayako; Itoh, Tomoo; Tukey, Robert H; Fujiwara, Ryoichi P42ES010337 Sci Rep (2013) 24104695 Exiting the NIEHS site 2013 
Importance of UDP-glucuronosyltransferase 1A1 expression in skin and its induction by UVB in neonata ...   Sumida, Kyohei; Kawana, Makiko; Kouno, Emi; Itoh, Tomoo; Takano, Shuhei; Narawa, Tomoya; Tukey ... P42ES010337 Mol Pharmacol (2013 Nov) 23950218 Exiting the NIEHS site 2013 
Insights into negative regulation by the glucocorticoid receptor from genome-wide profiling of infla ...   Uhlenhaut, N Henriette; Barish, Grant D; Yu, Ruth T; Downes, Michael; Karunasiri, Malith; Liddl ... P42ES010337 Mol Cell (2013 Jan 10) 23159735 Exiting the NIEHS site 2013 
Intestinal glucuronidation protects against chemotherapy-induced toxicity by irinotecan (CPT-11).   Chen, Shujuan; Yueh, Mei-Fei; Bigo, Cyril; Barbier, Olivier; Wang, Kepeng; Karin, Michael; Ngu ... P42ES010337 Proc Natl Acad Sci U S A (2013 Nov 19) 24191041 Exiting the NIEHS site 2013 
JNK inhibition reduces apoptosis and neovascularization in a murine model of age-related macular deg ...   Du, Hongjun; Sun, Xufang; Guma, Monica; Luo, Jing; Ouyang, Hong; Zhang, Xiaohui; Zeng, Jing; ... P42ES010337 Proc Natl Acad Sci U S A (2013 Feb 5) 23341606 Exiting the NIEHS site 2013 
Kisspeptin regulates gonadotropin genes via immediate early gene induction in pituitary gonadotropes ...   Witham, Emily A; Meadows, Jason D; Hoffmann, Hanne M; Shojaei, Shadi; Coss, Djurdjica; Kauffman ... P42ES010337 Mol Endocrinol (2013 Aug) 23770611 Exiting the NIEHS site 2013 
M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pat ...   Madsen, Daniel H; Leonard, Daniel; Masedunskas, Andrius; Moyer, Amanda; Jürgensen, Henrik Jesse ... P42ES010337 J Cell Biol (2013 Sep 16) 24019537 Exiting the NIEHS site 2013 
Msx1 homeodomain protein represses the αGSU and GnRH receptor genes during gonadotrope development.   Xie, Huimin; Cherrington, Brian D; Meadows, Jason D; Witham, Emily A; Mellon, Pamela L P42ES010337 Mol Endocrinol (2013 Mar) 23371388 Exiting the NIEHS site 2013 
Neurokinin B causes acute GnRH secretion and repression of GnRH transcription in GT1-7 GnRH neurons.   Glidewell-Kenney, Christine A; Shao, Paul P; Iyer, Anita K; Grove, Anna M H; Meadows, Jason D; ... P42ES010337 Mol Endocrinol (2013 Mar) 23393128 Exiting the NIEHS site 2013 
p38α inhibits liver fibrogenesis and consequent hepatocarcinogenesis by curtailing accumulation of r ...   Sakurai, Toshiharu; Kudo, Masatoshi; Umemura, Atsushi; He, Guobin; Elsharkawy, Ahmed M; Seki, ... P42ES010337 Cancer Res (2013 Jan 01) 23271722 Exiting the NIEHS site 2013 
PPARγ signaling and metabolism: the good, the bad and the future.   Ahmadian, Maryam; Suh, Jae Myoung; Hah, Nasun; Liddle, Christopher; Atkins, Annette R; Downes, ... P42ES010337 Nat Med (2013 May) 23652116 Exiting the NIEHS site 2013 
Road to exercise mimetics: targeting nuclear receptors in skeletal muscle.   Fan, Weiwei; Atkins, Annette R; Yu, Ruth T; Downes, Michael; Evans, Ronald M P42ES010337 J Mol Endocrinol (2013 Dec) 24280961 Exiting the NIEHS site 2013 
Sestrins orchestrate cellular metabolism to attenuate aging.   Lee, Jun Hee; Budanov, Andrei V; Karin, Michael P42ES010337 Cell Metab (2013 Dec 03) 24055102 Exiting the NIEHS site 2013 
The effect of Ca2+ ions and ionic strength on Mn(II) oxidation by spores of the marine Bacillus sp. ...   Toyoda, Kazuhiro; Tebo, Bradley M P42ES010337 Geochim Cosmochim Acta (2013 Jan 15) 29176910 Exiting the NIEHS site 2013 
Toll-like receptors in alcoholic liver disease, non-alcoholic steatohepatitis and carcinogenesis.   Roh, Yoon Seok; Seki, Ekihiro P42ES010337 J Gastroenterol Hepatol (2013 Aug) 23855294 Exiting the NIEHS site 2013 
Transforming growth factor-β signaling in hepatocytes promotes hepatic fibrosis and carcinogenesis i ...   Yang, Ling; Inokuchi, Sayaka; Roh, Yoon Seok; Song, Jingyi; Loomba, Rohit; Park, Eek Joong; Se ... P42ES010337 Gastroenterology (2013 May) 23391818 Exiting the NIEHS site 2013 
Using membrane transporters to improve crops for sustainable food production.   Schroeder, Julian I; Delhaize, Emmanuel; Frommer, Wolf B; Guerinot, Mary Lou; Harrison, Maria J ... P42ES010337 Nature (2013 May 02) 23636397 Exiting the NIEHS site 2013 
A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical ...   Seki, Ekihiro; Brenner, David A; Karin, Michael P42ES010337 Gastroenterology (2012 Aug) 22705006 Exiting the NIEHS site 2012 
Androgen receptor repression of GnRH gene transcription.   Brayman, Melissa J; Pepa, Patricia A; Berdy, Sara E; Mellon, Pamela L P42ES010337 Mol Endocrinol (2012 Jan) 22074952 Exiting the NIEHS site 2012 
Androgen receptor repression of gonadotropin-releasing hormone gene transcription via enhancer 1.   Brayman, Melissa J; Pepa, Patricia A; Mellon, Pamela L P42ES010337 Mol Cell Endocrinol (2012 Nov 05) 22877652 Exiting the NIEHS site 2012 
Arsenic decreases RXRα-dependent transcription of CYP3A and suppresses immune regulators in hepatocy ...   Noreault-Conti, Trisha L; Fellows, Abigail; Jacobs, Judith M; Trask, Heidi W; Strom, Stephen C; ... P42ES010337 Int Immunopharmacol (2012 Apr) 22310326 Exiting the NIEHS site 2012 
Bcl-xL-mediated remodeling of rod and cone synaptic mitochondria after postnatal lead exposure: elec ...   Perkins, Guy A; Scott, Ray; Perez, Alex; Ellisman, Mark H; Johnson, Jerry E; Fox, Donald A P42ES010337 Mol Vis (2012) 23288995 Exiting the NIEHS site 2012 
Cadmium-induced proteome remodeling regulated by Spc1/Sty1 and Zip1 in fission yeast.   Guo, Lan; Ghassemian, Majid; Komives, Elizabeth A; Russell, Paul P42ES010337 Toxicol Sci (2012 Sep) 22610605 Exiting the NIEHS site 2012 
Congenital hypothyroidism mutations affect common folding and trafficking in the α/β-hydrolase fold ...   De Jaco, Antonella; Dubi, Noga; Camp, Shelley; Taylor, Palmer P42ES010337 FEBS J (2012 Dec) 23035660 Exiting the NIEHS site 2012 
CYLD and HCC: when being too sensitive to your dirty neighbors results in self-destruction.   Font-Burgada, Joan; Seki, Ekihiro; Karin, Michael P42ES010337 Cancer Cell (2012 Jun 12) 22698394 Exiting the NIEHS site 2012 
Feedback inhibition by thiols outranks glutathione depletion: a luciferase-based screen reveals glut ...   Jobe, Timothy O; Sung, Dong-Yul; Akmakjian, Garo; Pham, Allis; Komives, Elizabeth A; Mendoza-Có ... P42ES010337 Plant J (2012 Jun) 22283708 Exiting the NIEHS site 2012 
FOXL2 is involved in the synergy between activin and progestins on the follicle-stimulating hormone ...   Ghochani, Yasmin; Saini, Jasjit K; Mellon, Pamela L; Thackray, Varykina G P42ES010337 Endocrinology (2012 Apr) 22294749 Exiting the NIEHS site 2012 
FXR and PXR: potential therapeutic targets in cholestasis.   Jonker, Johan W; Liddle, Christopher; Downes, Michael P42ES010337 J Steroid Biochem Mol Biol (2012 Jul) 21801835 Exiting the NIEHS site 2012 
Hepatic expression of HCV RNA-dependent RNA polymerase triggers innate immune signaling and cytokine ...   Yu, Guann-Yi; He, Guobin; Li, Chia-Yang; Tang, Martin; Grivennikov, Sergei; Tsai, Wan-Ting; Wu ... P42ES010337 Mol Cell (2012 Oct 26) 22959272 Exiting the NIEHS site 2012 
Inherited genetic variants in autism-related CNTNAP2 show perturbed trafficking and ATF6 activation.   Falivelli, Giulia; De Jaco, Antonella; Favaloro, Flores Lietta; Kim, Hyuck; Wilson, Jennifer; D ... P42ES010337 Hum Mol Genet (2012 Nov 1) 22872700 Exiting the NIEHS site 2012 
Iron(III)-doped, silica nanoshells: a biodegradable form of silica.   Pohaku Mitchell, Kristina K; Liberman, Alexander; Kummel, Andrew C; Trogler, William C P42ES010337 J Am Chem Soc (2012 Aug 29) 22871140 Exiting the NIEHS site 2012 
Liver epithelial cells proliferate under hypoxia and protect the liver from ischemic injury via expr ...   Abe, Yuki; Uchinami, Hiroshi; Kudoh, Kazuhiro; Nakagawa, Yasuhiko; Ise, Norihito; Watanabe, Go ... P42ES010337 Surgery (2012 Nov) 22575885 Exiting the NIEHS site 2012 
Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3.   Lee, Jun Hee; Budanov, Andrei V; Talukdar, Saswata; Park, Eek Joong; Park, Hae Li; Park, Hwan- ... P42ES010337 Cell Metab (2012 Sep 05) 22958918 Exiting the NIEHS site 2012 
Obesity, inflammation, and liver cancer.   Sun, Beicheng; Karin, Michael P42ES010337 J Hepatol (2012 Mar) 22120206 Exiting the NIEHS site 2012 
Pregnane-x-receptor controls hepatic glucuronidation during pregnancy and neonatal development in hu ...   Chen, Shujuan; Yueh, Mei-Fei; Evans, Ronald M; Tukey, Robert H P42ES010337 Hepatology (2012 Aug) 22371261 Exiting the NIEHS site 2012 
Prenatal exposure to low levels of androgen accelerates female puberty onset and reproductive senesc ...   Witham, Emily A; Meadows, Jason D; Shojaei, Shadi; Kauffman, Alexander S; Mellon, Pamela L P42ES010337 Endocrinology (2012 Sep) 22778229 Exiting the NIEHS site 2012 
Processing of cholinesterase-like α/β-hydrolase fold proteins: alterations associated with congenita ...   De Jaco, Antonella; Comoletti, Davide; Dubi, Noga; Camp, Shelley; Taylor, Palmer P42ES010337 Protein Pept Lett (2012 Feb) 21933121 Exiting the NIEHS site 2012 
Reduced expression of UGT1A1 in intestines of humanized UGT1 mice via inactivation of NF-κB leads to ...   Fujiwara, Ryoichi; Chen, Shujuan; Karin, Michael; Tukey, Robert H P42ES010337 Gastroenterology (2012 Jan) 21983082 Exiting the NIEHS site 2012 
Stress levels of glucocorticoids inhibit LHβ-subunit gene expression in gonadotrope cells.   Breen, Kellie M; Thackray, Varykina G; Hsu, Tracy; Mak-McCully, Rachel A; Coss, Djurdjica; Mell ... P42ES010337 Mol Endocrinol (2012 Oct) 22851703 Exiting the NIEHS site 2012 
Targeting the pregnane X receptor in liver injury.   Li, Tao; Yu, Ruth T; Atkins, Annette R; Downes, Michael; Tukey, Robert H; Evans, Ronald M P42ES010337 Expert Opin Ther Targets (2012 Nov) 22913318 Exiting the NIEHS site 2012 
Triclocarban mediates induction of xenobiotic metabolism through activation of the constitutive andr ...   Yueh, Mei-Fei; Li, Tao; Evans, Ronald M; Hammock, Bruce; Tukey, Robert H P42ES004699, P42ES010337 PLoS One (2012) 22761658 Exiting the NIEHS site 2012 
Analysis of in situ manganese(II) oxidation in the Columbia River and offshore plume: linking Aurant ...   Anderson, C R; Davis, R E; Bandolin, N S; Baptista, A M; Tebo, B M P42ES010337 Environ Microbiol (2011 Jun) 21418498 Exiting the NIEHS site 2011 
AtHKT1;1 mediates nernstian sodium channel transport properties in Arabidopsis root stelar cells.   Xue, Shaowu; Yao, Xuan; Luo, Wei; Jha, Deepa; Tester, Mark; Horie, Tomoaki; Schroeder, Julian ... P42ES010337 PLoS One (2011) 21931830 Exiting the NIEHS site 2011 
Culturable Rhodobacter and Shewanella species are abundant in estuarine turbidity maxima of the Colu ...   Bräuer, S L; Adams, C; Kranzler, K; Murphy, D; Xu, M; Zuber, P; Simon, H M; Baptista, A M; T ... P42ES010337 Environ Microbiol (2011 Mar) 20977571 Exiting the NIEHS site 2011 
Distinct localization of collagen Q and PRiMA forms of acetylcholinesterase at the neuromuscular jun ...   Bernard, Véronique; Girard, Emmanuelle; Hrabovska, Anna; Camp, Shelley; Taylor, Palmer; Plaud, ... P42ES010337 Mol Cell Neurosci (2011 Jan) 20883790 Exiting the NIEHS site 2011 
Ectopic expression of CD74 in Ikkβ-deleted mouse hepatocytes.   Koch, Katherine S; Leffert, Hyam L P42ES010337 Acta Histochem (2011 Jul) 20569972 Exiting the NIEHS site 2011 
Evolution of abscisic acid synthesis and signaling mechanisms.   Hauser, Felix; Waadt, Rainer; Schroeder, Julian I P42ES010337 Curr Biol (2011 May 10) 21549957 Exiting the NIEHS site 2011 
Extrahepatic cancer suppresses nuclear receptor-regulated drug metabolism.   Kacevska, Marina; Downes, Michael R; Sharma, Rohini; Evans, Ronald M; Clarke, Stephen J; Liddle ... P42ES010337 Clin Cancer Res (2011 May 15) 21498392 Exiting the NIEHS site 2011 
Fibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liver.   Österreicher, Christoph H; Penz-Österreicher, Melitta; Grivennikov, Sergei I; Guma, Monica; Kolt ... P42ES010337 Proc Natl Acad Sci U S A (2011 Jan 04) 21173249 Exiting the NIEHS site 2011 
GWAS of butyrylcholinesterase activity identifies four novel loci, independent effects within BCHE a ...   Benyamin, Beben; Middelberg, Rita P; Lind, Penelope A; Valle, Anne M; Gordon, Scott; Nyholt, D ... P42ES010337 Hum Mol Genet (2011 Nov 15) 21862451 Exiting the NIEHS site 2011 
Hypothalamic dysregulation and infertility in mice lacking the homeodomain protein Six6.   Larder, Rachel; Clark, Daniel D; Miller, Nichol L G; Mellon, Pamela L P42ES010337 J Neurosci (2011 Jan 12) 21228153 Exiting the NIEHS site 2011 
Inhibition of human UGT2B7 gene expression in transgenic mice by the constitutive androstane recepto ...   Yueh, M F; Mellon, P L; Tukey, R H P42ES010337 Mol Pharmacol (2011 Jun) 21415305 Exiting the NIEHS site 2011 
K+ transport by the OsHKT2;4 transporter from rice with atypical Na+ transport properties and compet ...   Horie, Tomoaki; Brodsky, Dennis E; Costa, Alex; Kaneko, Toshiyuki; Lo Schiavo, Fiorella; Katsuh ... P42ES010337 Plant Physiol (2011 Jul) 21610181 Exiting the NIEHS site 2011 
Long-distance transport, vacuolar sequestration, tolerance, and transcriptional responses induced by ...   Mendoza-Cózatl, David G; Jobe, Timothy O; Hauser, Felix; Schroeder, Julian I P42ES010337 Curr Opin Plant Biol (2011 Oct) 21820943 Exiting the NIEHS site 2011 
Naturally occurring variations in the human cholinesterase genes: heritability and association with ...   Valle, Anne M; Radic, Zoran; Rana, Brinda K; Mahboubi, Vafa; Wessel, Jennifer; Shih, Pei-an Be ... P42ES010337 J Pharmacol Exp Ther (2011 Jul) 21493754 Exiting the NIEHS site 2011 
Quantitative transcriptomic analysis of abscisic acid-induced and reactive oxygen species-dependent ...   Bohmer, Maik; Schroeder, Julian I P42ES010337 Plant J (2011 Jul) 21426425 Exiting the NIEHS site 2011 
Roles of intracellular hydrogen peroxide accumulation in abscisic acid signaling in Arabidopsis guar ...   Jannat, Rayhanur; Uraji, Misugi; Morofuji, Miho; Islam, Mohammad Muzahidul; Bloom, Rachel E; Na ... P42ES010337 J Plant Physiol (2011 Nov 01) 21665322 Exiting the NIEHS site 2011 
Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation.   Holzer, Ryan G; Park, Eek-Joong; Li, Ning; Tran, Helen; Chen, Monica; Choi, Crystal; Solinas, ... P42ES010337 Cell (2011 Sep 30) 21962514 Exiting the NIEHS site 2011 
The crystal structure of the α-neurexin-1 extracellular region reveals a hinge point for mediating s ...   Miller, Meghan T; Mileni, Mauro; Comoletti, Davide; Stevens, Raymond C; Harel, Michal; Taylor, ... P42ES010337 Structure (2011 Jun 08) 21620717 Exiting the NIEHS site 2011 
A humanized UGT1 mouse model expressing the UGT1A1*28 allele for assessing drug clearance by UGT1A1- ...   Cai, Hongliang; Nguyen, Nghia; Peterkin, Vincent; Yang, Young-Sun; Hotz, Kathy; La Placa, Deir ... P42ES010337 Drug Metab Dispos (2010 May) 20124398 Exiting the NIEHS site 2010 
Arsenic tolerance in Arabidopsis is mediated by two ABCC-type phytochelatin transporters.   Song, Won-Yong; Park, Jiyoung; Mendoza-Cozatl, David G; Suter-Grotemeyer, Marianne; Shim, Dongh ... P42ES010337 Proc Natl Acad Sci U S A (2010 Dec 7) 21078981 Exiting the NIEHS site 2010 
Cis and trans actions of the cholinesterase-like domain within the thyroglobulin dimer.   Wang, Xiaofan; Lee, Jaemin; Di Jeso, Bruno; Treglia, A Sonia; Comoletti, Davide; Dubi, Noga; T ... P42ES010337 J Biol Chem (2010 Jun 04) 20353937 Exiting the NIEHS site 2010 
Conformational remodeling of femtomolar inhibitor-acetylcholinesterase complexes in the crystalline ...   Bourne, Yves; Radić, Zoran; Taylor, Palmer; Marchot, Pascale P42ES010337 J Am Chem Soc (2010 Dec 29) 21090615 Exiting the NIEHS site 2010 
Contributions of selective knockout studies to understanding cholinesterase disposition and function ...   Camp, Shelley; Zhang, Limin; Krejci, Eric; Dobbertin, Alexandre; Bernard, Veronique; Girard, E ... P42ES010337 Chem Biol Interact (2010 Sep 6) 20153304 Exiting the NIEHS site 2010 
Developmental hyperbilirubinemia and CNS toxicity in mice humanized with the UDP glucuronosyltransfe ...   Fujiwara, Ryoichi; Nguyen, Nghia; Chen, Shujuan; Tukey, Robert H P42ES010337 Proc Natl Acad Sci U S A (2010 Mar 16) 20194756 Exiting the NIEHS site 2010 
Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF e ...   Park, Eek Joong; Lee, Jun Hee; Yu, Guann-Yi; He, Guobin; Ali, Syed Raza; Holzer, Ryan G; Oster ... P42ES010337 Cell (2010 Jan 22) 20141834 Exiting the NIEHS site 2010 
Differential sodium and potassium transport selectivities of the rice OsHKT2;1 and OsHKT2;2 transpor ...   Yao, Xuan; Horie, Tomoaki; Xue, Shaowu; Leung, Ho-Yin; Katsuhara, Maki; Brodsky, Dennis E; Wu, ... P42ES010337 Plant Physiol (2010 Jan) 19889878 Exiting the NIEHS site 2010 
From Split to Sibenik: the tortuous pathway in the cholinesterase field.   Taylor, Palmer P42ES010337 Chem Biol Interact (2010 Sep 6) 20493179 Exiting the NIEHS site 2010 
Guard cell signal transduction network: advances in understanding abscisic acid, CO2, and Ca2+ signa ...   Kim, Tae-Houn; Böhmer, Maik; Hu, Honghong; Nishimura, Noriyuki; Schroeder, Julian I P42ES010337 Annu Rev Plant Biol (2010) 20192751 Exiting the NIEHS site 2010 
H2O2 in plant peroxisomes: an in vivo analysis uncovers a Ca(2+)-dependent scavenging system.   Costa, Alex; Drago, Ilaria; Behera, Smrutisanjita; Zottini, Michela; Pizzo, Paola; Schroeder, ... P42ES010337 Plant J (2010 Jun 01) 20230493 Exiting the NIEHS site 2010 
Hepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress ...   He, Guobin; Yu, Guann-Yi; Temkin, Vladislav; Ogata, Hisanobu; Kuntzen, Christian; Sakurai, Tos ... P42ES010337 Cancer Cell (2010 Mar 16) 20227042 Exiting the NIEHS site 2010 
High-affinity K(+) transport in Arabidopsis: AtHAK5 and AKT1 are vital for seedling establishment an ...   Pyo, Young Jae; Gierth, Markus; Schroeder, Julian I; Cho, Myeon Haeng P42ES010337 Plant Physiol (2010 Jun) 20413648 Exiting the NIEHS site 2010 
Hypothesis: Targeted Ikkβ deletion upregulates MIF signaling responsiveness and MHC class II express ...   Koch, Katherine S; Leffert, Hyam L P42ES010337 Hepat Med (2010 Mar) 23997575 Exiting the NIEHS site 2010 
Metabolism: Tick, tock, a beta-cell clock.   Lamia, Katja A; Evans, Ronald M P42ES010337 Nature (2010 Jul 29) 20671699 Exiting the NIEHS site 2010 
Mitochondrial rejuvenation after induced pluripotency.   Suhr, Steven T; Chang, Eun Ah; Tjong, Jonathan; Alcasid, Nathan; Perkins, Guy A; Goissis, Marc ... P42ES010337 PLoS One (2010 Nov 23) 21124794 Exiting the NIEHS site 2010 
Neuroligin trafficking deficiencies arising from mutations in the alpha/beta-hydrolase fold protein ...   De Jaco, Antonella; Lin, Michael Z; Dubi, Noga; Comoletti, Davide; Miller, Meghan T; Camp, She ... P42ES010337 J Biol Chem (2010 Sep 10) 20615874 Exiting the NIEHS site 2010 
Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies.   Lee, Jun Hee; Budanov, Andrei V; Park, Eek Joong; Birse, Ryan; Kim, Teddy E; Perkins, Guy A; O ... P42ES010337 Science (2010 Mar 05) 20203043 Exiting the NIEHS site 2010 
Sestrins at the crossroad between stress and aging.   Lee, Jun Hee; Bodmer, Rolf; Bier, Ethan; Karin, Michael P42ES010337 Aging (Albany NY) (2010 Jun) 20606249 Exiting the NIEHS site 2010 
Stressin' Sestrins take an aging fight.   Budanov, Andrei V; Lee, Jun Hee; Karin, Michael P42ES010337 EMBO Mol Med (2010 Oct) 20878915 Exiting the NIEHS site 2010 
Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR ...   Bourne, Yves; Radic, Zoran; Aráoz, Rómulo; Talley, Todd T; Benoit, Evelyne; Servent, Denis; Ta ... P42ES010337 Proc Natl Acad Sci U S A (2010 Mar 30) 20224036 Exiting the NIEHS site 2010 
Structural insights into the exquisite selectivity of neurexin/neuroligin synaptic interactions.   Leone, Philippe; Comoletti, Davide; Ferracci, Géraldine; Conrod, Sandrine; Garcia, Simon U; Tay ... P42ES010337 EMBO J (2010 Jul 21) 20543817 Exiting the NIEHS site 2010 
The genome of the Gram-positive metal- and sulfate-reducing bacterium Desulfotomaculum reducens stra ...   Junier, Pilar; Junier, Thomas; Podell, Sheila; Sims, David R; Detter, John C; Lykidis, Athanas ... P42ES010337 Environ Microbiol (2010 Oct) 20482743 Exiting the NIEHS site 2010 
The macromolecular architecture of extracellular domain of alphaNRXN1: domain organization, flexibil ...   Comoletti, Davide; Miller, Meghan T; Jeffries, Cy M; Wilson, Jennifer; Demeler, Borries; Taylor ... P42ES010337 Structure (2010 Aug 11) 20696403 Exiting the NIEHS site 2010 
Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation.   Takahashi, Hiroyuki; Ogata, Hisanobu; Nishigaki, Reiko; Broide, David H; Karin, Michael P42ES010337 Cancer Cell (2010 Jan 19) 20129250 Exiting the NIEHS site 2010 
Tonoplast-localized Abc2 transporter mediates phytochelatin accumulation in vacuoles and confers cad ...   Mendoza-Cózatl, David G; Zhai, Zhiyang; Jobe, Timothy O; Akmakjian, Garo Z; Song, Won-Yong; Lim ... P42ES010337 J Biol Chem (2010 Dec 24) 20937798 Exiting the NIEHS site 2010 
A lymphotoxin-driven pathway to hepatocellular carcinoma.   Haybaeck, Johannes; Zeller, Nicolas; Wolf, Monika Julia; Weber, Achim; Wagner, Ulrich; Kurrer, ... P42ES010337 Cancer Cell (2009 Oct 06) 19800575 Exiting the NIEHS site 2009 
Angiotensin-converting-enzyme 2 inhibits liver fibrosis in mice.   Osterreicher, Christoph H; Taura, Kojiro; De Minicis, Samuele; Seki, Ekihiro; Penz-Osterreicher, ... P42ES010337 Hepatology (2009 Sep) 19650157 Exiting the NIEHS site 2009 
ARS5 is a component of the 26S proteasome complex, and negatively regulates thiol biosynthesis and a ...   Sung, Dong-Yul; Kim, Tae-Houn; Komives, Elizabeth A; Mendoza-Cózatl, David G; Schroeder, Julian ... P42ES010337 Plant J (2009 Sep) 19453443 Exiting the NIEHS site 2009 
Aurantimonas manganoxydans, sp. nov. and Aurantimonas litoralis, sp. nov.: Mn(II) oxidizing represen ...   Anderson, C R; Dick, G J; Chu, M-L; Cho, J-C; Davis, R E; Bräuer, S L; Tebo, B M P42ES010337 Geomicrobiol J (2009 Apr 1) 19768133 Exiting the NIEHS site 2009 
Centaurin-like protein Cnt5 contributes to arsenic and cadmium resistance in fission yeast.   Vashisht, Ajay Amar; Kennedy, Patrick Joseph; Russell, Paul P42ES010337 FEMS Yeast Res (2009 Mar) 19076239 Exiting the NIEHS site 2009 
Chapter 2 Correlated light and electron microscopy/electron tomography of mitochondria in situ.   Perkins, Guy A; Sun, Mei G; Frey, Terrence G P42ES010337 Methods Enzymol (2009) 19348881 Exiting the NIEHS site 2009 
Dynamics of mitochondrial structure during apoptosis and the enigma of Opa1.   Yamaguchi, Ryuji; Perkins, Guy P42ES010337 Biochim Biophys Acta (2009 Aug) 19245786 Exiting the NIEHS site 2009 
HKT transporter-mediated salinity resistance mechanisms in Arabidopsis and monocot crop plants.   Horie, Tomoaki; Hauser, Felix; Schroeder, Julian I P42ES010337 Trends Plant Sci (2009 Dec) 19783197 Exiting the NIEHS site 2009 
Influence of differential expression of acetylcholinesterase in brain and muscle on respiration.   Boudinot, Eliane; Bernard, Véronique; Camp, Shelley; Taylor, Palmer; Champagnat, Jean; Krejci, ... P42ES010337 Respir Physiol Neurobiol (2009 Jan 01) 18977317 Exiting the NIEHS site 2009 
Mn(II) oxidation is catalyzed by heme peroxidases in "Aurantimonas manganoxydans" strain SI85-9A1 an ...   Anderson, C R; Johnson, H A; Caputo, N; Davis, R E; Torpey, J W; Tebo, B M P42ES010337 Appl Environ Microbiol (2009 Jun) 19411418 Exiting the NIEHS site 2009 
Necdin, a Prader-Willi syndrome candidate gene, regulates gonadotropin-releasing hormone neurons dur ...   Miller, Nichol L G; Wevrick, Rachel; Mellon, Pamela L P42ES010337 Hum Mol Genet (2009 Jan 15) 18930956 Exiting the NIEHS site 2009 
New insights into mitochondrial structure during cell death.   Perkins, Guy; Bossy-Wetzel, Ella; Ellisman, Mark H P42ES010337 Exp Neurol (2009 Aug) 19464290 Exiting the NIEHS site 2009 
Plant ion channels: gene families, physiology, and functional genomics analyses.   Ward, John M; Mäser, Pascal; Schroeder, Julian I P42ES010337 Annu Rev Physiol (2009) 18842100 Exiting the NIEHS site 2009 
Structural mechanism of abscisic acid binding and signaling by dimeric PYR1.   Nishimura, Noriyuki; Hitomi, Kenichi; Arvai, Andrew S; Rambo, Robert P; Hitomi, Chiharu; Cutler ... P42ES010337 Science (2009 Dec 04) 19933100 Exiting the NIEHS site 2009 
Studies on induction of lamotrigine metabolism in transgenic UGT1 mice.   Argikar, U A; Senekeo-Effenberger, K; Larson, E E; Tukey, R H; Remmel, R P P42ES010337 Xenobiotica (2009 Nov) 19845433 Exiting the NIEHS site 2009 
Targeted deletion of hepatocyte Ikkbeta confers growth advantages.   Koch, Katherine S; Maeda, Shin; He, Guobin; Karin, Michael; Leffert, Hyam L P42ES010337 Biochem Biophys Res Commun (2009 Mar 06) 19171122 Exiting the NIEHS site 2009 
Targeting of acetylcholinesterase in neurons in vivo: a dual processing function for the proline-ric ...   Dobbertin, Alexandre; Hrabovska, Anna; Dembele, Korami; Camp, Shelley; Taylor, Palmer; Krejci, ... P42ES010337 J Neurosci (2009 Apr 8) 19357277 Exiting the NIEHS site 2009 
A genome-wide screen of genes involved in cadmium tolerance in Schizosaccharomyces pombe.   Kennedy, Patrick J; Vashisht, Ajay A; Hoe, Kwang-Lae; Kim, Dong-Uk; Park, Han-Oh; Hayles, Jacq ... P42ES010337 Toxicol Sci (2008 Nov) 18684775 Exiting the NIEHS site 2008 
Acetylcholinesterase expression in muscle is specifically controlled by a promoter-selective enhance ...   Camp, Shelley; De Jaco, Antonella; Zhang, Limin; Marquez, Michael; De la Torre, Brian; Taylor, ... P42ES010337 J Neurosci (2008 Mar 05) 18322091 Exiting the NIEHS site 2008 
An HPLC-ICP-MS technique for determination of cadmium-phytochelatins in genetically modified Arabido ...   Sadi, Baki B M; Vonderheide, Anne P; Gong, Ji-Ming; Schroeder, Julian I; Shann, Jodi R; Caruso, ... P42ES010337 J Chromatogr B Analyt Technol Biomed Life Sci (2008 Jan 1) 18065298 Exiting the NIEHS site 2008 
Characterization of the solution structure of a neuroligin/beta-neurexin complex.   Comoletti, Davide; Grishaev, Alexander; Whitten, Andrew E; Taylor, Palmer; Trewhella, Jill P42ES010337 Chem Biol Interact (2008 Sep 25) 18550038 Exiting the NIEHS site 2008 
Control of mRNA stability by SAPKs.   Rodríguez-Gabriel, Miguel A; Russell, Paul P42ES010337 Top Curr Genet (2008 Jan 01) 21738496 Exiting the NIEHS site 2008 
Direct identification of a bacterial manganese(II) oxidase, the multicopper oxidase MnxG, from spore ...   Dick, Gregory J; Torpey, Justin W; Beveridge, Terry J; Tebo, Bradley M P42ES010337 Appl Environ Microbiol (2008 Mar) 18165363 Exiting the NIEHS site 2008 
Disruption of the ugt1 locus in mice resembles human Crigler-Najjar type I disease.   Nguyen, Nghia; Bonzo, Jessica A; Chen, Shujuan; Chouinard, Sarah; Kelner, Michael J; Hardiman, ... P42ES010337 J Biol Chem (2008 Mar 21) 18180294 Exiting the NIEHS site 2008 
Expression of the novel wheat gene TM20 confers enhanced cadmium tolerance to bakers' yeast.   Kim, Yu-Young; Kim, Do-Young; Shim, Donghwan; Song, Won-Yong; Lee, Joohyun; Schroeder, Julian ... P42ES010337 J Biol Chem (2008 Jun 06) 18411273 Exiting the NIEHS site 2008 
Genomic insights into Mn(II) oxidation by the marine alphaproteobacterium Aurantimonas sp. strain SI ...   Dick, Gregory J; Podell, Sheila; Johnson, Hope A; Rivera-Espinoza, Yadira; Bernier-Latmani, Riz ... P42ES010337 Appl Environ Microbiol (2008 May) 18344346 Exiting the NIEHS site 2008 
Identification of high levels of phytochelatins, glutathione and cadmium in the phloem sap of Brassi ...   Mendoza-Cózatl, David G; Butko, Emerald; Springer, Franziska; Torpey, Justin W; Komives, Elizab ... P42ES010337 Plant J (2008 Apr) 18208526 Exiting the NIEHS site 2008 
In vitro studies indicate a quinone is involved in bacterial Mn(II) oxidation.   Johnson, Hope A; Tebo, Bradley M P42ES010337 Arch Microbiol (2008 Jan) 17673976 Exiting the NIEHS site 2008 
Liver cancer stem cells.   Sell, Stewart; Leffert, Hyam L P42ES010337 J Clin Oncol (2008 Jun 10) 18539957 Exiting the NIEHS site 2008 
Mitochondrial fragmentation in neurodegeneration.   Knott, Andrew B; Perkins, Guy; Schwarzenbacher, Robert; Bossy-Wetzel, Ella P42ES010337 Nat Rev Neurosci (2008 Jul) 18568013 Exiting the NIEHS site 2008 
NeuroD1 and Mash1 temporally regulate GnRH receptor gene expression in immortalized mouse gonadotrop ...   Cherrington, Brian D; Bailey, Janice S; Diaz, Alejandro L; Mellon, Pamela L P42ES010337 Mol Cell Endocrinol (2008 Nov 25) 18760324 Exiting the NIEHS site 2008 
NF-kappaB and cancer-identifying targets and mechanisms.   Naugler, Willscott E; Karin, Michael P42ES010337 Curr Opin Genet Dev (2008 Feb) 18440219 Exiting the NIEHS site 2008 
Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent ...   Yamaguchi, Ryuji; Lartigue, Lydia; Perkins, Guy; Scott, Ray T; Dixit, Amruta; Kushnareva, Yuli ... P42ES010337 Mol Cell (2008 Aug 22) 18691924 Exiting the NIEHS site 2008 
p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling.   Budanov, Andrei V; Karin, Michael P42ES010337 Cell (2008 Aug 08) 18692468 Exiting the NIEHS site 2008 
SLAC1 is required for plant guard cell S-type anion channel function in stomatal signalling.   Vahisalu, Triin; Kollist, Hannes; Wang, Yong-Fei; Nishimura, Noriyuki; Chan, Wai-Yin; Valerio, ... P42ES010337 Nature (2008 Mar 27) 18305484 Exiting the NIEHS site 2008 
Trafficking of cholinesterases and neuroligins mutant proteins. An association with autism.   De Jaco, Antonella; Comoletti, Davide; King, Charles C; Taylor, Palmer P42ES010337 Chem Biol Interact (2008 Sep 25) 18555979 Exiting the NIEHS site 2008 
Cr(III) is indirectly oxidized by the Mn(II)-oxidizing bacterium Bacillus sp. strain SG-1.   Murray, Karen J; Tebo, Bradley M P42ES010337 Environ Sci Technol (2007 Jan 15) 17310717 Exiting the NIEHS site 2007 
Expression of the human UGT1 locus in transgenic mice by 4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio ...   Senekeo-Effenberger, Kathy; Chen, Shujuan; Brace-Sinnokrak, Erin; Bonzo, Jessica A; Yueh, Mei-F ... P42ES010337 Drug Metab Dispos (2007 Mar) 17151188 Exiting the NIEHS site 2007 
Human CYP1A1GFP expression in transgenic mice serves as a biomarker for environmental toxicant expos ...   Operaña, Theresa N; Nguyen, Nghia; Chen, Shujuan; Beaton, Deirdre; Tukey, Robert H P42ES010337 Toxicol Sci (2007 Jan) 17065433 Exiting the NIEHS site 2007 
Identification of an arsenic tolerant double mutant with a thiol-mediated component and increased ar ...   Sung, Dong-Yul; Lee, David; Harris, Hugh; Raab, Andrea; Feldmann, Jörg; Meharg, Andrew; Kumabe ... P42ES010337 Plant J (2007 Mar) 17335514 Exiting the NIEHS site 2007 
Nrf2-Keap1 signaling pathway regulates human UGT1A1 expression in vitro and in transgenic UGT1 mice.   Yueh, Mei-Fei; Tukey, Robert H P42ES010337 J Biol Chem (2007 Mar 23) 17259171 Exiting the NIEHS site 2007 
PGC-1beta controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, ...   Sonoda, Junichiro; Mehl, Isaac R; Chong, Ling-Wa; Nofsinger, Russell R; Evans, Ronald M P42ES010337 Proc Natl Acad Sci U S A (2007 Mar 20) 17360356 Exiting the NIEHS site 2007 
Rice OsHKT2;1 transporter mediates large Na+ influx component into K+-starved roots for growth.   Horie, Tomoaki; Costa, Alex; Kim, Tae Houn; Han, Min Jung; Horie, Rie; Leung, Ho-Yin; Miyao, ... P42ES010337 EMBO J (2007 Jun 20) 17541409 Exiting the NIEHS site 2007 
Structural analysis of the synaptic protein neuroligin and its beta-neurexin complex: determinants f ...   Fabrichny, Igor P; Leone, Philippe; Sulzenbacher, Gerlind; Comoletti, Davide; Miller, Meghan T; ... P42ES010337 Neuron (2007 Dec 20) 18093521 Exiting the NIEHS site 2007 
Synaptic arrangement of the neuroligin/beta-neurexin complex revealed by X-ray and neutron scatterin ...   Comoletti, Davide; Grishaev, Alexander; Whitten, Andrew E; Tsigelny, Igor; Taylor, Palmer; Trew ... P42ES010337 Structure (2007 Jun) 17562316 Exiting the NIEHS site 2007 
The NIEHS Environmental Health Sciences Data Resource Portal: placing advanced technologies in servi ...   Pezzoli, Keith; Tukey, Robert; Sarabia, Hiram; Zaslavsky, Ilya; Miranda, Marie Lynn; Suk, Will ... P42ES010337, P42ES010356 Environ Health Perspect (2007 Apr) 17450225 Exiting the NIEHS site 2007 
The role of chrysin and the ah receptor in induction of the human UGT1A1 gene in vitro and in transg ...   Bonzo, Jessica A; Bélanger, Alain; Tukey, Robert H P42ES010337 Hepatology (2007 Feb) 17256720 Exiting the NIEHS site 2007 
Toxicity of Cr(lll) to Shewanella sp. strain MR-4 during Cr(VI) reduction.   Bencheikh-Latmani, Rizlan; Obraztsova, Anna; Mackey, Mason R; Ellisman, Mark H; Tebo, Bradley M P42ES010337 Environ Sci Technol (2007 Jan 01) 17265950 Exiting the NIEHS site 2007 
A mutation linked with autism reveals a common mechanism of endoplasmic reticulum retention for the ...   De Jaco, Antonella; Comoletti, Davide; Kovarik, Zrinka; Gaietta, Guido; Radic, Zoran; Lockridge ... P42ES010337 J Biol Chem (2006 Apr 07) 16434405 Exiting the NIEHS site 2006 
A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipog ...   Zhou, Jie; Zhai, Yonggong; Mu, Ying; Gong, Haibiao; Uppal, Hirdesh; Toma, David; Ren, Songron ... P42ES010337 J Biol Chem (2006 May 26) 16556603 Exiting the NIEHS site 2006 
An improved grafting technique for mature Arabidopsis plants demonstrates long-distance shoot-to-roo ...   Chen, Alice; Komives, Elizabeth A; Schroeder, Julian I P42ES010337 Plant Physiol (2006 May) 16531489 Exiting the NIEHS site 2006 
Behavior of mice with mutations in the conserved region deleted in velocardiofacial/DiGeorge syndrom ...   Long, Jeffrey M; LaPorte, Patricia; Merscher, Sandra; Funke, Birgit; Saint-Jore, Bruno; Puech, ... P42ES010337 Neurogenetics (2006 Nov) 16900388 Exiting the NIEHS site 2006 
Benefit of farnesoid X receptor inhibition in obstructive cholestasis.   Stedman, Catherine; Liddle, Christopher; Coulter, Sally; Sonoda, Junichiro; Alvarez, Jacqueline ... P42ES010337 Proc Natl Acad Sci U S A (2006 Jul 25) 16844773 Exiting the NIEHS site 2006 
Cip1 and Cip2 are novel RNA-recognition-motif proteins that counteract Csx1 function during oxidativ ...   Martín, Victoria; Rodríguez-Gabriel, Miguel A; McDonald, W Hayes; Watt, Stephen; Yates 3rd, Joh ... P42ES010337 Mol Biol Cell (2006 Mar) 16407405 Exiting the NIEHS site 2006 
Gene selection, alternative splicing, and post-translational processing regulate neuroligin selectiv ...   Comoletti, Davide; Flynn, Robyn E; Boucard, Antony A; Demeler, Borries; Schirf, Virgil; Shi, J ... P42ES010337 Biochemistry (2006 Oct 24) 17042500 Exiting the NIEHS site 2006 
Immune-privileged embryonic Swiss mouse STO and STO cell-derived progenitor cells: major histocompat ...   Koch, Katherine S; Son, Kyung-Hwa; Maehr, Rene; Pellicciotta, Illenia; Ploegh, Hidde L; Zanetti ... P42ES010337 Immunology (2006 Sep) 16836618 Exiting the NIEHS site 2006 
International Union of Pharmacology. LX. Retinoic acid receptors.   Germain, Pierre; Chambon, Pierre; Eichele, Gregor; Evans, Ronald M; Lazar, Mitchell A; Leid, M ... P42ES010337 Pharmacol Rev (2006 Dec) 17132850 Exiting the NIEHS site 2006 
International Union of Pharmacology. LXIII. Retinoid X receptors.   Germain, Pierre; Chambon, Pierre; Eichele, Gregor; Evans, Ronald M; Lazar, Mitchell A; Leid, M ... P42ES010337 Pharmacol Rev (2006 Dec) 17132853 Exiting the NIEHS site 2006 
Ligand-induced conformational changes in the acetylcholine-binding protein analyzed by hydrogen-deut ...   Shi, Jianxin; Koeppe, Julia R; Komives, Elizabeth A; Taylor, Palmer P42ES010337 J Biol Chem (2006 Apr 28) 16484218 Exiting the NIEHS site 2006 
Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N ...   Sakurai, Toshiharu; Maeda, Shin; Chang, Lufen; Karin, Michael P42ES010337 Proc Natl Acad Sci U S A (2006 Jul 11) 16807293 Exiting the NIEHS site 2006 
Manganese(II)-oxidizing Bacillus spores in Guaymas Basin hydrothermal sediments and plumes.   Dick, Gregory J; Lee, Yifan E; Tebo, Bradley M P42ES010337 Appl Environ Microbiol (2006 May) 16672456 Exiting the NIEHS site 2006 
Upf1, an RNA helicase required for nonsense-mediated mRNA decay, modulates the transcriptional respo ...   Rodríguez-Gabriel, Miguel A; Watt, Stephen; Bähler, Jürg; Russell, Paul P42ES010337 Mol Cell Biol (2006 Sep) 16914721 Exiting the NIEHS site 2006 
Arsenite inhibition of CYP1A1 induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin is independent of cel ...   Bonzo, Jessica A; Chen, Shujuan; Galijatovic, Alema; Tukey, Robert H P42ES010337 Mol Pharmacol (2005 Apr) 15630080 Exiting the NIEHS site 2005 
Distinct signaling pathways respond to arsenite and reactive oxygen species in Schizosaccharomyces p ...   Rodríguez-Gabriel, Miguel A; Russell, Paul P42ES010337 Eukaryot Cell (2005 Aug) 16087744 Exiting the NIEHS site 2005 
Embryonic mouse STO cell-derived xenografts express hepatocytic functions in the livers of nonimmuno ...   Zhang, Mingjun; Joseph, Brigid; Gupta, Sanjeev; Guest, I; Xu, Meng; Sell, Stewart; Son, Kyung ... P42ES010337 Stem Cells (2005 Feb) 15671142 Exiting the NIEHS site 2005 
Enhanced salt tolerance mediated by AtHKT1 transporter-induced Na unloading from xylem vessels to xy ...   Sunarpi; Horie, Tomoaki; Motoda, Jo; Kubo, Masahiro; Yang, Hua; Yoda, Kinya; Horie, Rie; Chan, ... P42ES010337 Plant J (2005 Dec) 16359386 Exiting the NIEHS site 2005 
ERK kinase inhibition stabilizes the aryl hydrocarbon receptor: implications for transcriptional act ...   Chen, Shujuan; Operaña, Theresa; Bonzo, Jessica; Nguyen, Nghia; Tukey, Robert H P42ES010337 J Biol Chem (2005 Feb 11) 15572374 Exiting the NIEHS site 2005 
Geomicrobiology of manganese(II) oxidation.   Tebo, Bradley M; Johnson, Hope A; McCarthy, James K; Templeton, Alexis S P42ES010337 Trends Microbiol (2005 Sep) 16054815 Exiting the NIEHS site 2005 
Global transcriptional profiling of Shewanella oneidensis MR-1 during Cr(VI) and U(VI) reduction.   Bencheikh-Latmani, Rizlan; Williams, Sarah Middleton; Haucke, Lisa; Criddle, Craig S; Wu, Liyou ... P42ES010337 Appl Environ Microbiol (2005 Nov) 16269787 Exiting the NIEHS site 2005 
IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemica ...   Maeda, Shin; Kamata, Hideaki; Luo, Jun-Li; Leffert, Hyam; Karin, Michael P42ES010337 Cell (2005 Jul 01) 15989949 Exiting the NIEHS site 2005 
Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MA ...   Kamata, Hideaki; Honda, Shi-Ichi; Maeda, Shin; Chang, Lufen; Hirata, Hajime; Karin, Michael P42ES010337 Cell (2005 Mar 11) 15766528 Exiting the NIEHS site 2005 
The innate immune response under the control of the LXR pathway.   Valledor, Annabel F P42ES010337 Immunobiology (2005) 16164019 Exiting the NIEHS site 2005 
The role of protein kinase C in regulation of TCDD-mediated CYP1A1 gene expression.   Machemer, Daniel E W; Tukey, Robert H P42ES010337 Toxicol Sci (2005 Sep) 15947024 Exiting the NIEHS site 2005 
Tissue-specific, inducible, and hormonal control of the human UDP-glucuronosyltransferase-1 (UGT1) l ...   Chen, Shujuan; Beaton, Deirdre; Nguyen, Nghia; Senekeo-Effenberger, Kathy; Brace-Sinnokrak, Eri ... P42ES010337 J Biol Chem (2005 Nov 11) 16155002 Exiting the NIEHS site 2005 
Activation of liver X receptors and retinoid X receptors prevents bacterial-induced macrophage apopt ...   Valledor, Annabel F; Hsu, Li-Chung; Ogawa, Sumito; Sawka-Verhelle, Dominique; Karin, Michael; G ... P42ES010337 Proc Natl Acad Sci U S A (2004 Dec 21) 15601766 Exiting the NIEHS site 2004 
Balanol analogues probe specificity determinants and the conformational malleability of the cyclic 3 ...   Akamine, Pearl; Madhusudan; Brunton, Laurence L; Ou, Horng D; Canaves, Jaume M; Xuong, Nguyen-h ... P42ES010337 Biochemistry (2004 Jan 13) 14705934 Exiting the NIEHS site 2004 
Expanded characterization of the social interaction abnormalities in mice lacking Dvl1.   Long, J M; LaPorte, P; Paylor, R; Wynshaw-Boris, A P42ES010337 Genes Brain Behav (2004 Feb) 14960015 Exiting the NIEHS site 2004 
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer.   Greten, Florian R; Eckmann, Lars; Greten, Tim F; Park, Jin Mo; Li, Zhi-Wei; Egan, Laurence J; ... P42ES010337 Cell (2004 Aug 06) 15294155 Exiting the NIEHS site 2004 
Imaging dynamic redox changes in mammalian cells with green fluorescent protein indicators.   Dooley, Colette T; Dore, Timothy M; Hanson, George T; Jackson, W Coyt; Remington, S James; Tsie ... P42ES010337 J Biol Chem (2004 May 21) 14985369 Exiting the NIEHS site 2004 
Overexpression of phytochelatin synthase in Arabidopsis leads to enhanced arsenic tolerance and cadm ...   Li, Yujing; Dhankher, Om Parkash; Carreira, Laura; Lee, David; Chen, Alice; Schroeder, Julian ... P42ES010337 Plant Cell Physiol (2004 Dec) 15653797 Exiting the NIEHS site 2004 
Repression of IFN-gamma expression by peroxisome proliferator-activated receptor gamma.   Cunard, Robyn; Eto, Yoko; Muljadi, Julie T; Glass, Christopher K; Kelly, Carolyn J; Ricote, Me ... P42ES010337 J Immunol (2004 Jun 15) 15187132 Exiting the NIEHS site 2004 
Structural characterization of recombinant soluble rat neuroligin 1: mapping of secondary structure ...   Hoffman, Ross C; Jennings, Lori L; Tsigelny, Igor; Comoletti, Davide; Flynn, Robyn E; Sudhof, ... P42ES010337 Biochemistry (2004 Feb 17) 14769026 Exiting the NIEHS site 2004 
Structural organization of the murine microsomal glutathione S-transferase gene (MGST1) from the 129 ...   Kelner, Michael J; Bagnell, Richard D; Morgenstern, Ralf P42ES010337 Biochim Biophys Acta (2004 May 25) 15157743 Exiting the NIEHS site 2004 
The Arg451Cys-neuroligin-3 mutation associated with autism reveals a defect in protein processing.   Comoletti, Davide; De Jaco, Antonella; Jennings, Lori L; Flynn, Robyn E; Gaietta, Guido; Tsigel ... P42ES010337 J Neurosci (2004 May 19) 15152050 Exiting the NIEHS site 2004 
The human CYP1A1 gene is regulated in a developmental and tissue-specific fashion in transgenic mice ...   Galijatovic, Alema; Beaton, Deirdre; Nguyen, Nghia; Chen, Shujuan; Bonzo, Jessica; Johnson, Ra ... P42ES010337 J Biol Chem (2004 Jun 04) 15037607 Exiting the NIEHS site 2004 
The two NF-kappaB activation pathways and their role in innate and adaptive immunity.   Bonizzi, Giuseppina; Karin, Michael P42ES010337 Trends Immunol (2004 Jun) 15145317 Exiting the NIEHS site 2004 
ars1, an Arabidopsis mutant exhibiting increased tolerance to arsenate and increased phosphate uptak ...   Lee, David A; Chen, Alice; Schroeder, Julian I P42ES010337 Plant J (2003 Sep) 12940956 Exiting the NIEHS site 2003 
Basal expression of the human MAPEG members microsomal glutathione transferase 1 and prostaglandin E ...   Ekström, Lena; Lyrenäs, Louise; Jakobsson, Per-Johan; Morgenstern, Ralf; Kelner, Michael J P42ES010337 Biochim Biophys Acta (2003 Jun 19) 12818425 Exiting the NIEHS site 2003 
Bcl-xL overexpression blocks bax-mediated mitochondrial contact site formation and apoptosis in rod ...   He, Lihua; Perkins, Guy A; Poblenz, Ann T; Harris, Jeffrey B; Hung, Michael; Ellisman, Mark H; ... P42ES010337 Proc Natl Acad Sci U S A (2003 Feb 4) 12540825 Exiting the NIEHS site 2003 
Cometabolism of Cr(VI) by Shewanella oneidensis MR-1 produces cell-associated reduced chromium and i ...   Middleton, Sarah S; Latmani, Rizlan Bencheikh; Mackey, Mason R; Ellisman, Mark H; Tebo, Bradley ... P42ES004911, P42ES010337 Biotechnol Bioeng (2003 Sep 20) 12889027 Exiting the NIEHS site 2003 
Direct analysis of the kinetic profiles of organophosphate-acetylcholinesterase adducts by MALDI-TOF ...   Jennings, Lori L; Malecki, Michael; Komives, Elizabeth A; Taylor, Palmer P42ES010337 Biochemistry (2003 Sep 23) 12974645 Exiting the NIEHS site 2003 
Hepatic progenitor cell lines from allyl alcohol-treated adult rats are derived from gamma-irradiate ...   Zhang, Mingjun; Sell, Stewart; Leffert, Hyam L P42ES010337 Stem Cells (2003) 12832698 Exiting the NIEHS site 2003 
IKK beta is required for peripheral B cell survival and proliferation.   Li, Zhi-Wei; Omori, Sidne A; Labuda, Tord; Karin, Michael; Rickert, Robert C P42ES010337 J Immunol (2003 May 01) 12707341 Exiting the NIEHS site 2003 
IKKbeta is required for prevention of apoptosis mediated by cell-bound but not by circulating TNFalp ...   Maeda, Shin; Chang, Lufen; Li, Zhi-Wei; Luo, Jun-Li; Leffert, Hyam; Karin, Michael P42ES010337 Immunity (2003 Nov) 14614859 Exiting the NIEHS site 2003 
Involvement of the xenobiotic response element (XRE) in Ah receptor-mediated induction of human UDP- ...   Yueh, Mei-Fei; Huang, Yue-Hua; Hiller, Anita; Chen, Shujuan; Nguyen, Nghia; Tukey, Robert H P42ES010337 J Biol Chem (2003 Apr 25) 12566446 Exiting the NIEHS site 2003 
Localization and functional characterization of metal-binding sites in phytochelatin synthases.   Maier, Thomas; Yu, Chao; Küllertz, Gerhard; Clemens, Stephan P42ES010337 Planta (2003 Dec) 12905027 Exiting the NIEHS site 2003 
Long-distance root-to-shoot transport of phytochelatins and cadmium in Arabidopsis.   Gong, Ji-Ming; Lee, David A; Schroeder, Julian I P42ES010337 Proc Natl Acad Sci U S A (2003 Aug 19) 12909714 Exiting the NIEHS site 2003 
Nanosecond dynamics of the mouse acetylcholinesterase cys69-cys96 omega loop.   Shi, Jianxin; Tai, Kaihsu; McCammon, J Andrew; Taylor, Palmer; Johnson, David A P42ES010337 J Biol Chem (2003 Aug 15) 12759360 Exiting the NIEHS site 2003 
PPARgamma and PPARdelta negatively regulate specific subsets of lipopolysaccharide and IFN-gamma tar ...   Welch, John S; Ricote, Mercedes; Akiyama, Taro E; Gonzalez, Frank J; Glass, Christopher K P42ES010337 Proc Natl Acad Sci U S A (2003 May 27) 12740443 Exiting the NIEHS site 2003 
RNA-binding protein Csx1 mediates global control of gene expression in response to oxidative stress.   Rodríguez-Gabriel, Miguel A; Burns, Gavin; McDonald, W Hayes; Martín, Victoria; Yates 3rd, John ... P42ES010337 EMBO J (2003 Dec 01) 14633985 Exiting the NIEHS site 2003 
The role of the Ah receptor and p38 in benzo[a]pyrene-7,8-dihydrodiol and benzo[a]pyrene-7,8-dihydro ...   Chen, Shujuan; Nguyen, Nghia; Tamura, Kumiko; Karin, Michael; Tukey, Robert H P42ES010337 J Biol Chem (2003 May 23) 12637498 Exiting the NIEHS site 2003 
Altered shoot/root Na+ distribution and bifurcating salt sensitivity in Arabidopsis by genetic disru ...   Mäser, Pascal; Eckelman, Brendan; Vaidyanathan, Rama; Horie, Tomoaki; Fairbairn, David J; Kubo, ... P42ES010337 FEBS Lett (2002 Nov 06) 12417304 Exiting the NIEHS site 2002 
Derivation, characterization, and phenotypic variation of hepatic progenitor cell lines isolated fro ...   Yin, Li; Sun, Mingzeng; Ilic, Zoran; Leffert, Hyam L; Sell, Stewart P42ES010337 Hepatology (2002 Feb) 11826404 Exiting the NIEHS site 2002 
Doublecortin is required in mice for lamination of the hippocampus but not the neocortex.   Corbo, Joseph C; Deuel, Thomas A; Long, Jeffrey M; LaPorte, Patricia; Tsai, Elena; Wynshaw-Bori ... P42ES010337 J Neurosci (2002 Sep 01) 12196578 Exiting the NIEHS site 2002 
Enzymatic manganese(II) oxidation by metabolically dormant spores of diverse Bacillus species.   Francis, Chris A; Tebo, Bradley M P42ES010337 Appl Environ Microbiol (2002 Feb) 11823231 Exiting the NIEHS site 2002 
Glycine residues in potassium channel-like selectivity filters determine potassium selectivity in fo ...   Maser, Pascal; Hosoo, Yoshihiro; Goshima, Shinobu; Horie, Tomoaki; Eckelman, Brendan; Yamada, ... P42ES010337 Proc Natl Acad Sci U S A (2002 Apr 30) 11959905 Exiting the NIEHS site 2002 
Hypersensitivity of abscisic acid-induced cytosolic calcium increases in the Arabidopsis farnesyltra ...   Allen, Gethyn J; Murata, Yoshiyuki; Chu, Sarah P; Nafisi, Majse; Schroeder, Julian I P42ES010337 Plant Cell (2002 Jul) 12119381 Exiting the NIEHS site 2002 
Identification and functional characterization of UDP-glucuronosyltransferases UGT1A8*1, UGT1A8*2 an ...   Huang, Yue-Hua; Galijatovic, Alema; Nguyen, Nghia; Geske, Donald; Beaton, Deirdre; Green, Judi ... P42ES010337 Pharmacogenetics (2002 Jun) 12042666 Exiting the NIEHS site 2002 
Inhibitors of different structure induce distinguishing conformations in the omega loop, Cys69-Cys96 ...   Shi, Jianxin; Radic', Zoran; Taylor, Palmer P42ES010337 J Biol Chem (2002 Nov 08) 12196517 Exiting the NIEHS site 2002 
Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition.   Park, Jin Mo; Greten, Florian R; Li, Zhi-Wei; Karin, Michael P42ES010337 Science (2002 Sep 20) 12202685 Exiting the NIEHS site 2002 
Mice with a homozygous deletion of the Mgat2 gene encoding UDP-N-acetylglucosamine:alpha-6-D-mannosi ...   Wang, Yan; Schachter, Harry; Marth, Jamey D P42ES010337 Biochim Biophys Acta (2002 Dec 19) 12417412 Exiting the NIEHS site 2002 
Regulation of cytokine expression by ligands of peroxisome proliferator activated receptors.   Cunard, Robyn; Ricote, Mercedes; DiCampli, Dennis; Archer, D Clay; Kahn, Daniel A; Glass, Chri ... P42ES010337 J Immunol (2002 Mar 15) 11884448 Exiting the NIEHS site 2002 
WY14,643, a PPAR alpha ligand, has profound effects on immune responses in vivo.   Cunard, Robyn; DiCampli, Dennis; Archer, D Clay; Stevenson, Jennifer L; Ricote, Mercedes; Glass ... P42ES010337 J Immunol (2002 Dec 15) 12471112 Exiting the NIEHS site 2002 
An integrated Arabidopsis annotation database for Affymetrix Genechip data analysis, and tools for r ...   Ghassemian, M; Waner, D; Tchieu, J; Gribskov, M; Schroeder, J I P42ES010337 Trends Plant Sci (2001 Oct) 11590042 Exiting the NIEHS site 2001 
Caenorhabditis elegans expresses a functional phytochelatin synthase.   Clemens, S; Schroeder, J I; Degenkolb, T P42ES010337 Eur J Biochem (2001 Jul) 11432729 Exiting the NIEHS site 2001 
DNA microarray analysis of gene expression in endothelial cells in response to 24-h shear stress.   Chen, B P; Li, Y S; Zhao, Y; Chen, K D; Li, S; Lao, J; Yuan, S; Shyy, J Y; Chien, S P42ES010337 Physiol Genomics (2001 Oct 10) 11595792 Exiting the NIEHS site 2001 
Enzymatic manganese(II) oxidation by a marine alpha-proteobacterium.   Francis, C A; Co, E M; Tebo, B M P42ES010337 Appl Environ Microbiol (2001 Sep) 11526000 Exiting the NIEHS site 2001 
Functional pleiotropy of an intramolecular triplex-forming fragment from the 3'-UTR of the rat Pigr ...   Fabregat, I; Koch, K S; Aoki, T; Atkinson, A E; Dang, H; Amosova, O; Fresco, J R; Schildkraut ... P42ES010337 Physiol Genomics (2001 Mar 8) 11242589 Exiting the NIEHS site 2001 
Modeling human congenital disorder of glycosylation type IIa in the mouse: conservation of asparagin ...   Wang, Y; Tan, J; Sutton-Smith, M; Ditto, D; Panico, M; Campbell, R M; Varki, N M; Long, J M; ... P42ES010337 Glycobiology (2001 Dec) 11805078 Exiting the NIEHS site 2001 
Structural organization of the microsomal glutathione S-transferase gene (MGST1) on chromosome 12p13 ...   Kelner, M J; Bagnell, R D; Montoya, M A; Estes, L A; Forsberg, L; Morgenstern, R P42ES010337 J Biol Chem (2000 Apr 28) 10777602 Exiting the NIEHS site 2000 
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