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Your Environment. Your Health.

Who We Fund: Publication Detail

Project Title: NMDA RECEPTOR FUNCTION IN LEAD NEUROTOXICITY
PI: Guilarte, Tomas R
Institution: Florida International University
Grant Number: R01ES006189

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 47 publications
Export to Excel (http://www.niehs.nih.gov//portfolio/index.cfm/portfolio/grantpubdetail/grant_number/R01ES006189/format/excel)
Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Chronic developmental lead exposure increases μ-opiate receptor levels in the adolescent rat brain.   Albores-Garcia, Damaris; McGlothan, Jennifer L; Bursac, Zoran; Guilarte, Tomás R R01ES006189 Neurotoxicology (2021 01) 33248188 Exiting the NIEHS site 2021 
Awake delta and theta-rhythmic hippocampal network modes during intermittent locomotor behaviors in ...   Schultheiss, Nathan W; Schlecht, Maximilian; Jayachandran, Maanasa; Brooks, Deborah R; McGlothan ... R01ES006189 Behav Neurosci (2020 Dec) 32672989 Exiting the NIEHS site 2020 
From the Cover: 7,8-Dihydroxyflavone Rescues Lead-Induced Impairment of Vesicular Release: A Novel T ...   Zhang, Xiao-Lei; McGlothan, Jennifer L; Miry, Omid; Stansfield, Kirstie H; Loth, Meredith K; St ... R01ES006189, T32ES007322 Toxicol Sci (2018 01 01) 29029315 Exiting the NIEHS site 2018 
Subunit-specific NMDAR antagonism dissociates schizophrenia subtype-relevant oscillopathies associat ...   Pittman-Polletta, Benjamin; Hu, Kun; Kocsis, Bernat R01ES006189 Sci Rep (2018 08 02) 30072757 Exiting the NIEHS site 2018 
In Vitro Effects of Lead on Gene Expression in Neural Stem Cells and Associations between Up-regulat ...   Wagner, Peter J; Park, Hae-Ryung; Wang, Zhaoxi; Kirchner, Rory; Wei, Yongyue; Su, Li; Stanfiel ... P30ES000002, P30ES009089, P30ES023515, R01ES006189 Environ Health Perspect (2017 04) 27562236 Exiting the NIEHS site 2017 
Chronic early life lead (Pb2+) exposure alters presynaptic vesicle pools in hippocampal synapses.   Guariglia, Sara Rose; Stansfield, Kirstie H; McGlothan, Jennifer; Guilarte, Tomas R P30ES009089, R01ES006189 BMC Pharmacol Toxicol (2016 11 02) 27802838 Exiting the NIEHS site 2016 
Neurochemistry of lead and manganese.   Austin, Rachel Narehood; Freeman, Jennifer L; Guilarte, Tomás R R01ES006189 Metallomics (2016 06 01) 27261156 Exiting the NIEHS site 2016 
Early-life lead exposure recapitulates the selective loss of parvalbumin-positive GABAergic interneu ...   Stansfield, K H; Ruby, K N; Soares, B D; McGlothan, J L; Liu, X; Guilarte, T R P30ES009089, R01ES006189, T32ES007322 Transl Psychiatry (2015 Mar 10) 25756805 Exiting the NIEHS site 2015 
Presynaptic mechanisms of lead neurotoxicity: effects on vesicular release, vesicle clustering and m ...   Zhang, Xiao-Lei; Guariglia, Sara R; McGlothan, Jennifer L; Stansfield, Kirstie H; Stanton, Patr ... P30ES009089, R01ES006189 PLoS One (2015) 26011056 Exiting the NIEHS site 2015 
Chronic exposure of mutant DISC1 mice to lead produces sex-dependent abnormalities consistent with s ...   Abazyan, Bagrat; Dziedzic, Jenifer; Hua, Kegang; Abazyan, Sofya; Yang, Chunxia; Mori, Susumu; ... P30ES009089, R01ES006189 Schizophr Bull (2014 May) 23716713 Exiting the NIEHS site 2014 
Astrocytes release D-serine by a large vesicle.   Kang, N; Peng, H; Yu, Y; Stanton, P K; Guilarte, T R; Kang, J R01ES006189, R01ES007062 Neuroscience (2013 Jun 14) 23485803 Exiting the NIEHS site 2013 
Mechanisms of lead and manganese neurotoxicity.   Neal, April P; Guilarte, Tomas R R01ES006189 Toxicol Res (Camb) (2013 Mar 01) 25722848 Exiting the NIEHS site 2013 
Dysregulation of BDNF-TrkB signaling in developing hippocampal neurons by Pb(2+): implications for a ...   Stansfield, Kirstie H; Pilsner, J Richard; Lu, Quan; Wright, Robert O; Guilarte, Tomás R P30ES009089, R01ES006189 Toxicol Sci (2012 May) 22345308 Exiting the NIEHS site 2012 
Enhanced nitric oxide production during lead (Pbýýýýý) exposure recovers protein expression but not ...   Neal, April P; Stansfield, Kirstie H; Guilarte, Tomas R R01ES006189, T32ES007141 Brain Res (2012 Feb 23) 22265330 Exiting the NIEHS site 2012 
Is lead exposure in early life an environmental risk factor for Schizophrenia? Neurobiological conne ...   Guilarte, Tomás R; Opler, Mark; Pletnikov, Mikhail R01ES006189 Neurotoxicology (2012 Jun) 22178136 Exiting the NIEHS site 2012 
Lead exposure during synaptogenesis alters NMDA receptor targeting via NMDA receptor inhibition.   Neal, April P; Worley, Paul F; Guilarte, Tomas R R01ES006189, T32ES007141 Neurotoxicology (2011 Mar) 21192972 Exiting the NIEHS site 2011 
Lead exposure during synaptogenesis alters vesicular proteins and impairs vesicular release: potenti ...   Neal, April P; Stansfield, Kirstie H; Worley, Paul F; Thompson, Richard E; Guilarte, Tomas R R01ES006189, T32ES007141 Toxicol Sci (2010 Jul) 20375082 Exiting the NIEHS site 2010 
Molecular neurobiology of lead (Pb(2+)): effects on synaptic function.   Neal, April P; Guilarte, Tomas R R01ES006189 Mol Neurobiol (2010 Dec) 21042954 Exiting the NIEHS site 2010 
Developmental lead exposure impairs extinction of conditioned fear in young adult rats.   McGlothan, Jennifer L; Karcz-Kubicha, Marzena; Guilarte, Tomás R R01ES006189 Neurotoxicology (2008 Nov) 18662719 Exiting the NIEHS site 2008 
Dysregulation of glutamate carboxypeptidase II in psychiatric disease.   Guilarte, Tomás R; Hammoud, Dima A; McGlothan, Jennifer L; Caffo, Brian S; Foss, Catherine A; K ... R01ES006189 Schizophr Res (2008 Feb) 18191545 Exiting the NIEHS site 2008 
Environmental lead exposure during early life alters granule cell neurogenesis and morphology in the ...   Verina, T; Rohde, C A; Guilarte, T R R01ES006189 Neuroscience (2007 Mar 30) 17276012 Exiting the NIEHS site 2007 
Experience-dependent regulation of zif268 gene expression and spatial learning.   Toscano, Christopher D; McGlothan, Jennifer L; Guilarte, Tomas R R01ES006189, T32ES007141 Exp Neurol (2006 Jul) 16545374 Exiting the NIEHS site 2006 
Calcium/calmodulin-dependent protein kinase II activity and expression are altered in the hippocampu ...   Toscano, Christopher D; O'Callaghan, James P; Guilarte, Tomas R R01ES006189, T32ES007141 Brain Res (2005 May 17) 15862789 Exiting the NIEHS site 2005 
Glutamate carboxypeptidase II levels in rodent brain using [125I]DCIT quantitative autoradiography.   Guilarte, Tomás R; McGlothan, Jennifer L; Foss, Catherine A; Zhou, Jia; Heston, Warren D; Kozik ... R01ES006189 Neurosci Lett (2005 Oct 28) 16006038 Exiting the NIEHS site 2005 
Lead neurotoxicity: from exposure to molecular effects.   Toscano, Christopher D; Guilarte, Tomas R R01ES006189 Brain Res Brain Res Rev (2005 Nov) 16269318 Exiting the NIEHS site 2005 
Prenatal lead exposure and schizophrenia: a plausible neurobiologic connection.   Guilarte, Tomás R R01ES006189 Environ Health Perspect (2004 Sep) 15345353 Exiting the NIEHS site 2004 
Environmental enrichment reverses cognitive and molecular deficits induced by developmental lead exp ...   Guilarte, Tomás R; Toscano, Christopher D; McGlothan, Jennifer L; Weaver, Shelley A R01ES006189, T32ES007141 Ann Neurol (2003 Jan) 12509847 Exiting the NIEHS site 2003 
Lead exposure alters cyclic-AMP response element binding protein phosphorylation and binding activit ...   Toscano, Christopher D; McGlothan, Jennifer L; Guilarte, Tomás R R01ES006189, T32ES007141 Brain Res Dev Brain Res (2003 Nov 12) 14604762 Exiting the NIEHS site 2003 
Selective decrease in NR1 subunit splice variant mRNA in the hippocampus of Pb2+-exposed rats: impli ...   Guilarte, Tomás R; McGlothan, Jennifer L R01ES006189 Brain Res Mol Brain Res (2003 May 12) 12750004 Exiting the NIEHS site 2003 
Developmental Pb2+ exposure alters NMDAR subtypes and reduces CREB phosphorylation in the rat brain.   Toscano, Christopher D; Hashemzadeh-Gargari, Hossein; McGlothan, Jennifer L; Guilarte, Tomás R R01ES006189, T32ES007141 Brain Res Dev Brain Res (2002 Dec 15) 12480136 Exiting the NIEHS site 2002 
Is methamphetamine abuse a risk factor in parkinsonism?   Guilarte, T R R01ES006189, R01ES007062, T32ES007062 Neurotoxicology (2001 Dec) 11829406 Exiting the NIEHS site 2001 
Low level Pb(2+) exposure affects hippocampal protein kinase C gamma gene and protein expression in ...   Nihei, M K; McGlothan, J L; Toscano, C D; Guilarte, T R R01ES006189 Neurosci Lett (2001 Feb 09) 11165444 Exiting the NIEHS site 2001 
Molecular changes in glutamatergic synapses induced by Pb2+: association with deficits of LTP and sp ...   Nihei, M K; Guilarte, T R R01ES006189 Neurotoxicology (2001 Oct) 11770885 Exiting the NIEHS site 2001 
Hippocampal expression of N-methyl-D-aspartate receptor (NMDAR1) subunit splice variant mRNA is alte ...   Guilarte, T R; McGlothan, J L; Nihei, M K R01ES006189, T32ES007141 Brain Res Mol Brain Res (2000 Mar 29) 10762705 Exiting the NIEHS site 2000 
N-methyl-D-aspartate receptor subunit changes are associated with lead-induced deficits of long-term ...   Nihei, M K; Desmond, N L; McGlothan, J L; Kuhlmann, A C; Guilarte, T R R01ES006189, T32ES007141 Neuroscience (2000) 10938429 Exiting the NIEHS site 2000 
Divalent cations modulate N-methyl-D-aspartate receptor function at the glycine site.   Hashemzadeh-Gargari, H; Guilarte, T R R01ES006189 J Pharmacol Exp Ther (1999 Sep) 10454514 Exiting the NIEHS site 1999 
NMDAR-2A subunit protein expression is reduced in the hippocampus of rats exposed to Pb2+ during dev ...   Nihei, M K; Guilarte, T R R01ES006189, T32ES007141 Brain Res Mol Brain Res (1999 Mar 20) 10095076 Exiting the NIEHS site 1999 
Hippocampal NMDA receptor mRNA undergoes subunit specific changes during developmental lead exposure ...   Guilarte, T R; McGlothan, J L R01ES006189 Brain Res (1998 Apr 20) 9593842 Exiting the NIEHS site 1998 
Age-dependent effects of developmental lead exposure on performance in the Morris water maze.   Jett, D A; Kuhlmann, A C; Farmer, S J; Guilarte, T R R01ES006189 Pharmacol Biochem Behav (1997 May-Jun) 9164582 Exiting the NIEHS site 1997 
Developmental lead exposure causes spatial learning deficits in adult rats.   Kuhlmann, A C; McGlothan, J L; Guilarte, T R R01ES006189 Neurosci Lett (1997 Sep 19) 9350842 Exiting the NIEHS site 1997 
Glutamatergic system and developmental lead neurotoxicity.   Guilarte, T R R01ES006189 Neurotoxicology (1997) 9339815 Exiting the NIEHS site 1997 
Intrahippocampal administration of lead (Pb) impairs performance of rats in the Morris water maze.   Jett, D A; Kuhlmann, A C; Guilarte, T R R01ES006189 Pharmacol Biochem Behav (1997 May-Jun) 9164581 Exiting the NIEHS site 1997 
Pb2+ inhibits NMDA receptor function at high and low affinity sites: developmental and regional brai ...   Guilarte, T R R01ES006189 Neurotoxicology (1997) 9215987 Exiting the NIEHS site 1997 
Biochemical evidence of an interaction of lead at the zinc allosteric sites of the NMDA receptor com ...   Guilarte, T R; Miceli, R C; Jett, D A R01ES006189 Neurotoxicology (1995) 7603646 Exiting the NIEHS site 1995 
Developmental lead exposure alters N-methyl-D-aspartate and muscarinic cholinergic receptors in the ...   Jett, D A; Guilarte, T R R01ES006189 Neurotoxicology (1995) 7603647 Exiting the NIEHS site 1995 
Neurochemical aspects of hippocampal and cortical Pb2+ neurotoxicity.   Guilarte, T R; Miceli, R C; Jett, D A R01ES006189 Neurotoxicology (1994) 7854579 Exiting the NIEHS site 1994 
Chronic prenatal and postnatal Pb2+ exposure increases [3H]MK801 binding sites in adult rat forebrai ...   Guilarte, T R; Miceli, R C; Altmann, L; Weinsberg, F; Winneke, G; Wiegand, H R01ES006189 Eur J Pharmacol (1993 Oct 01) 8293792 Exiting the NIEHS site 1993 
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