| Project Title: | ANALYSIS OF AH RECEPTOR LIGAND BINDING SPECIFICITY |
|---|---|
| PI: | Denison, Michael Steven |
| Institution: | University Of California At Davis |
| Grant Number: | R01ES007685 |
These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.
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| Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
|---|---|---|---|---|---|
| An aryl hydrocarbon receptor from the caecilian Gymnopis multiplicata suggests low dioxin affinity i ... | Kazzaz, Sarah A; Giani Tagliabue, Sara; Franks, Diana G; Denison, Michael S; Hahn, Mark E; Bona ... | P42ES007381, R01ES007685, R15ES011130, R15ES011130 | Gen Comp Endocrinol (2020 Dec 01) |
32858041
|
2020 |
| Development of a novel recombinant cell line for detection and characterization of Ah receptor nucle ... | Hayashi, Ai; Denison, Michael S | P42ES004699, R01ES007685 | Toxicol In Vitro (2020 Aug) |
32333947
|
2020 |
| The Cellular and Molecular Determinants of Naphthoquinone-Dependent Activation of the Aryl Hydrocarb ... | Faber, Samantha C; Giani Tagliabue, Sara; Bonati, Laura; Denison, Michael S | P42ES004699, R01ES007685 | Int J Mol Sci (2020 Jun 09) |
32526934
|
2020 |
| A Biomimetic, One-Step Transformation of Simple Indolic Compounds to Malassezia-Related Alkaloids wi ... | Mexia, Nikitia; Koutrakis, Stamatis; He, Guochun; Skaltsounis, Alexios-Leandros; Denison, Micha ... | P42ES004699, R01ES007685 | Chem Res Toxicol (2019 11 18) |
31647221
|
2019 |
| Modeling the binding of diverse ligands within the Ah receptor ligand binding domain. | Giani Tagliabue, Sara; Faber, Samantha C; Motta, Stefano; Denison, Michael S; Bonati, Laura | R01ES007685, T32ES007059 | Sci Rep (2019 07 23) |
31337850
|
2019 |
| Comparative In Vitro and In Silico Analysis of the Selectivity of Indirubin as a Human Ah Receptor A ... | Faber, Samantha C; Soshilov, Anatoly A; Giani Tagliabue, Sara; Bonati, Laura; Denison, Michael ... | P42ES004699, R01ES007685 | Int J Mol Sci (2018 Sep 10) |
30201897
|
2018 |
| Ligand-induced perturbation of the HIF-2α:ARNT dimer dynamics. | Motta, Stefano; Minici, Claudia; Corrada, Dario; Bonati, Laura; Pandini, Alessandro | R01ES007685 | PLoS Comput Biol (2018 02) |
29489822
|
2018 |
| And Now for Something Completely Different: Diversity in Ligand-Dependent Activation of Ah Receptor ... | Denison, Michael S; Faber, Samantha C | P42ES004699, R01ES007685 | Curr Opin Toxicol (2017 Feb) |
28845473
|
2017 |
| Auto-induction mechanism of aryl hydrocarbon receptor 2 (AHR2) gene by TCDD-activated AHR1 and AHR2 ... | Bak, Su-Min; Iida, Midori; Soshilov, Anatoly A; Denison, Michael S; Iwata, Hisato; Kim, Eun-Yo ... | R01ES007685 | Arch Toxicol (2017 Jan) |
27188387
|
2017 |
| Editor's Highlight: Microbial-Derived 1,4-Dihydroxy-2-naphthoic Acid and Related Compounds as Aryl H ... | Cheng, Yating; Jin, Un-Ho; Davidson, Laurie A; Chapkin, Robert S; Jayaraman, Arul; Tamamis, Ph ... | R01ES007685, R01ES025713 | Toxicol Sci (2017 02) |
27837168
|
2017 |
| Molecular modeling of the AhR structure and interactions can shed light on ligand-dependent activati ... | Bonati, Laura; Corrada, Dario; Tagliabue, Sara Giani; Motta, Stefano | R01ES007685 | Curr Opin Toxicol (2017 Feb) |
28497129
|
2017 |
| Structural modeling of the AhR:ARNT complex in the bHLH-PASA-PASB region elucidates the key determin ... | Corrada, Dario; Denison, Michael S; Bonati, Laura | R01ES007685 | Mol Biosyst (2017 May 02) |
28393157
|
2017 |
| Deciphering Dimerization Modes of PAS Domains: Computational and Experimental Analyses of the AhR:AR ... | Corrada, Dario; Soshilov, Anatoly A; Denison, Michael S; Bonati, Laura | R01ES007685 | PLoS Comput Biol (2016 06) |
27295348
|
2016 |
| Development of a recombinant human ovarian (BG1) cell line containing estrogen receptor α and β for ... | Brennan, Jennifer C; Bassal, Arzoo; He, Guochun; Denison, Michael S | P42ES004699, R01ES007685, T32ES007059 | Environ Toxicol Chem (2016 Jan) |
26139245
|
2016 |
| Activation of the aryl hydrocarbon receptor by the widely used Src family kinase inhibitor 4-amino-5 ... | Frauenstein, Katrin; Tigges, Julia; Soshilov, Anatoly A; Kado, Sarah; Raab, Nadeshda; Fritsche, ... | R01ES007685 | Arch Toxicol (2015 Aug) |
25082669
|
2015 |
| An Aryl Hydrocarbon Receptor from the Salamander Ambystoma mexicanum Exhibits Low Sensitivity to 2,3 ... | Shoots, Jenny; Fraccalvieri, Domenico; Franks, Diana G; Denison, Michael S; Hahn, Mark E; Bonat ... | R01ES007685, R15ES011130, R15ES011130 | Environ Sci Technol (2015 Jun 02) |
25941739
|
2015 |
| Development of Species-Specific Ah Receptor-Responsive Third Generation CALUX Cell Lines with Enhanc ... | Brennan, Jennifer C; He, Guochun; Tsutsumi, Tomoaki; Zhao, Jing; Wirth, Edward; Fulton, Michae ... | P42ES004699, R01ES007685 | Environ Sci Technol (2015 Oct 6) |
26366531
|
2015 |
| Naturally occurring marine brominated indoles are aryl hydrocarbon receptor ligands/agonists. | DeGroot, Danica E; Franks, Diana G; Higa, Tatsuo; Tanaka, Junichi; Hahn, Mark E; Denison, Mich ... | P42ES004699, R01ES007685 | Chem Res Toxicol (2015 Jun 15) |
26001051
|
2015 |
| Pityriazepin and other potent AhR ligands isolated from Malassezia furfur yeast. | Mexia, Nikitia; Gaitanis, Georgios; Velegraki, Aristea; Soshilov, Anatoly; Denison, Michael S; ... | R01ES007685 | Arch Biochem Biophys (2015 Apr 1) |
25721496
|
2015 |
| Aryl hydrocarbon receptor control of a disease tolerance defence pathway. | Bessede, Alban; Gargaro, Marco; Pallotta, Maria T; Matino, Davide; Servillo, Giuseppe; Brunacci ... | R01ES007685 | Nature (2014 Jul 10) |
24930766
|
2014 |
| Cross-talk between aryl hydrocarbon receptor and the inflammatory response: a role for nuclear facto ... | Vogel, Christoph F A; Khan, Elaine M; Leung, Patrick S C; Gershwin, M Eric; Chang, W L William; ... | R01ES007685 | J Biol Chem (2014 Jan 17) |
24302727
|
2014 |
| Lack of ligand-selective binding of the aryl hydrocarbon receptor to putative DNA binding sites regu ... | DeGroot, Danica E; Hayashi, Ai; Denison, Michael S | P42ES004699, R01ES007685, T32ES007059 | Arch Biochem Biophys (2014 Jan 01) |
24200861
|
2014 |
| Ligand promiscuity of aryl hydrocarbon receptor agonists and antagonists revealed by site-directed m ... | Soshilov, Anatoly A; Denison, Michael S | P42ES004699, R01ES007685 | Mol Cell Biol (2014 May) |
24591650
|
2014 |
| Nucleotide specificity of DNA binding of the aryl hydrocarbon receptor:ARNT complex is unaffected by ... | DeGroot, Danica E; Denison, Michael S | P42ES004699, R01ES007685, T32ES007059 | Toxicol Sci (2014 Jan) |
24136190
|
2014 |
| Artificial neural networks for efficient clustering of conformational ensembles and their potential ... | Pandini, Alessandro; Fraccalvieri, Domenico; Bonati, Laura | R01ES007685 | Curr Top Med Chem (2013) |
23548025
|
2013 |
| Common commercial and consumer products contain activators of the aryl hydrocarbon (dioxin) receptor ... | Zhao, Bin; Bohonowych, Jessica E S; Timme-Laragy, Alicia; Jung, Dawoon; Affatato, Alessandra A; ... | P42ES004699, P42ES010356, R01ES007685 | PLoS One (2013) |
23441220
|
2013 |
| Comparative analysis of homology models of the AH receptor ligand binding domain: verification of st ... | Fraccalvieri, Domenico; Soshilov, Anatoly A; Karchner, Sibel I; Franks, Diana G; Pandini, Aless ... | P42ES004699, P42ES007381, R01ES007685 | Biochemistry (2013 Jan 29) |
23286227
|
2013 |
| Ginsenosides are novel naturally-occurring aryl hydrocarbon receptor ligands. | Hu, Qin; He, Guochun; Zhao, Jing; Soshilov, Anatoly; Denison, Michael S; Zhang, Aiqian; Yin, ... | P42ES004699, R01ES007685 | PLoS One (2013) |
23776647
|
2013 |
| Malassezia yeasts produce a collection of exceptionally potent activators of the Ah (dioxin) recepto ... | Magiatis, Prokopios; Pappas, Periklis; Gaitanis, George; Mexia, Nikitia; Melliou, Eleni; Galano ... | P42ES004699, R01ES007685 | J Invest Dermatol (2013 Aug) |
23448877
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2013 |
| Specific ligand binding domain residues confer low dioxin responsiveness to AHR1β of Xenopus laevis. | Odio, Camila; Holzman, Sarah A; Denison, Michael S; Fraccalvieri, Domenico; Bonati, Laura; Fran ... | R01ES007685, R15ES011130, R15ES011130 | Biochemistry (2013 Mar 12) |
23394719
|
2013 |
| A novel prenylflavone restricts breast cancer cell growth through AhR-mediated destabilization of ER ... | Tiong, Chi Tze; Chen, Chen; Zhang, Shi Jun; Li, Jun; Soshilov, Anatoly; Denison, Michael S; Le ... | R01ES007685 | Carcinogenesis (2012 May) |
22345291
|
2012 |
| Harmaline and harmalol inhibit the carcinogen-activating enzyme CYP1A1 via transcriptional and postt ... | El Gendy, Mohamed A M; Soshilov, Anatoly A; Denison, Michael S; El-Kadi, Ayman O S | R01ES007685 | Food Chem Toxicol (2012 Feb) |
22037238
|
2012 |
| Novel 2-amino-isoflavones exhibit aryl hydrocarbon receptor agonist or antagonist activity in a spec ... | Wall, Richard J; He, Guochun; Denison, Michael S; Congiu, Cenzo; Onnis, Valentina; Fernandes, ... | P42ES004699, R01ES007685 | Toxicology (2012 Jul 16) |
22507882
|
2012 |
| Transcriptional and posttranslational inhibition of dioxin-mediated induction of CYP1A1 by harmine a ... | El Gendy, Mohamed A M; Soshilov, Anatoly A; Denison, Michael S; El-Kadi, Ayman O S | R01ES007685 | Toxicol Lett (2012 Jan 5) |
22001777
|
2012 |
| 2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced MUC5AC expression: aryl hydrocarbon receptor-independent ... | Lee, Yong C; Oslund, Karen L; Thai, Philip; Velichko, Sharlene; Fujisawa, Tomoyuki; Duong, Tra ... | R01ES007685 | Am J Respir Cell Mol Biol (2011 Aug) |
20971882
|
2011 |
| Conformational and functional analysis of molecular dynamics trajectories by self-organising maps. | Fraccalvieri, Domenico; Pandini, Alessandro; Stella, Fabio; Bonati, Laura | R01ES007685 | BMC Bioinformatics (2011 May 14) |
21569575
|
2011 |
| Exactly the same but different: promiscuity and diversity in the molecular mechanisms of action of t ... | Denison, Michael S; Soshilov, Anatoly A; He, Guochun; DeGroot, Danica E; Zhao, Bin | P42ES004699, R01ES007685 | Toxicol Sci (2011 Nov) |
21908767
|
2011 |
| Identification of benzothiazole derivatives and polycyclic aromatic hydrocarbons as aryl hydrocarbon ... | He, Guochun; Zhao, Bin; Denison, Michael S | P42ES004699, R01ES007685 | Environ Toxicol Chem (2011 Aug) |
21590714
|
2011 |
| Ligand displaces heat shock protein 90 from overlapping binding sites within the aryl hydrocarbon re ... | Soshilov, Anatoly; Denison, Michael S | R01ES007685 | J Biol Chem (2011 Oct 07) |
21856752
|
2011 |
| New aryl hydrocarbon receptor homology model targeted to improve docking reliability. | Motto, Ilaria; Bordogna, Annalisa; Soshilov, Anatoly A; Denison, Michael S; Bonati, Laura | P42ES004699, R01ES007685 | J Chem Inf Model (2011 Nov 28) |
21981577
|
2011 |
| Predicting the accuracy of protein-ligand docking on homology models. | Bordogna, Annalisa; Pandini, Alessandro; Bonati, Laura | R01ES007685 | J Comput Chem (2011 Jan 15) |
20607693
|
2011 |
| The p38 MAPK inhibitor SB203580 induces cytochrome P450 1A1 gene expression in murine and human hepa ... | Korashy, Hesham M; Anwar-Mohamed, Anwar; Soshilov, Anatoly A; Denison, Michael S; El-Kadi, Ayma ... | R01ES007685 | Chem Res Toxicol (2011 Sep 19) |
21732638
|
2011 |
| Third-generation Ah receptor-responsive luciferase reporter plasmids: amplification of dioxin-respon ... | He, Guochun; Tsutsumi, Tomoaki; Zhao, Bin; Baston, David S; Zhao, Jing; Heath-Pagliuso, Sharon ... | P42ES004699, R01ES007685 | Toxicol Sci (2011 Oct) |
21775728
|
2011 |
| Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells. | Boitano, Anthony E; Wang, Jian; Romeo, Russell; Bouchez, Laure C; Parker, Albert E; Sutton, Su ... | P42ES004699, R01ES007685 | Science (2010 Sep 10) |
20688981
|
2010 |
| CH223191 is a ligand-selective antagonist of the Ah (Dioxin) receptor. | Zhao, Bin; Degroot, Danica E; Hayashi, Ai; He, Guochun; Denison, Michael S | P42ES004699, R01ES007685 | Toxicol Sci (2010 Oct) |
20634293
|
2010 |
| Mechanism-based common reactivity pattern (COREPA) modelling of aryl hydrocarbon receptor binding af ... | Petkov, P I; Rowlands, J C; Budinsky, R; Zhao, B; Denison, M S; Mekenyan, O | R01ES007685 | SAR QSAR Environ Res (2010 Jan 01) |
20373220
|
2010 |
| Detection of the TCDD binding-fingerprint within the Ah receptor ligand binding domain by structural ... | Pandini, Alessandro; Soshilov, Anatoly A; Song, Yujuan; Zhao, Jing; Bonati, Laura; Denison, Mi ... | R01ES007685 | Biochemistry (2009 Jun 30) |
19456125
|
2009 |
| Newspapers and newspaper ink contain agonists for the ah receptor. | Bohonowych, Jessica E S; Zhao, Bin; Timme-Laragy, Alicia; Jung, Dawoon; Di Giulio, Richard T; D ... | P42ES004699, P42ES010356, R01ES007685 | Toxicol Sci (2008 Apr) |
18203687
|
2008 |
| Role of the Per/Arnt/Sim domains in ligand-dependent transformation of the aryl hydrocarbon receptor ... | Soshilov, Anatoly; Denison, Michael S | R01ES007685 | J Biol Chem (2008 Nov 21) |
18806268
|
2008 |
| Analysis of dioxins in contaminated soils with the calux and caflux bioassays, an immunoassay, and g ... | Nording, Malin; Denison, Michael S; Baston, David; Persson, Ylva; Spinnel, Erik; Haglund, Pete ... | P42ES004699, R01ES007685 | Environ Toxicol Chem (2007 Jun) |
17571676
|
2007 |
| Computational approaches to shed light on molecular mechanisms in biological processes. | Moro, Giorgio; Bonati, Laura; Bruschi, Maurizio; Cosentino, Ugo; De Gioia, Luca; Fantucci, Pie ... | R01ES007685 | Theor Chem Acc (2007 May 01) |
21415934
|
2007 |
| Persistent binding of ligands to the aryl hydrocarbon receptor. | Bohonowych, Jessica E; Denison, Michael S | R01ES007685 | Toxicol Sci (2007 Jul) |
17431010
|
2007 |
| Structural and functional characterization of the aryl hydrocarbon receptor ligand binding domain by ... | Pandini, Alessandro; Denison, Michael S; Song, Yujuan; Soshilov, Anatoly A; Bonati, Laura | R01ES007685 | Biochemistry (2007 Jan 23) |
17223691
|
2007 |
| Determination of in vitro relative potency (REP) values for mono-ortho polychlorinated biphenyls aft ... | Peters, A K; Leonards, P E; Zhao, B; Bergman, A; Denison, M S; Van den Berg, M | P42ES004699, R01ES007685 | Toxicol Lett (2006 Sep 10) |
16750337
|
2006 |
| Interaction of diuron and related substituted phenylureas with the Ah receptor pathway. | Zhao, Bin; Baston, David S; Hammock, Bruce; Denison, Michael S | P42ES004699, R01ES007685 | J Biochem Mol Toxicol (2006) |
16788953
|
2006 |
| Interactions of polybrominated diphenyl ethers with the aryl hydrocarbon receptor pathway. | Peters, A K; Nijmeijer, S; Gradin, K; Backlund, M; Bergman, A; Poellinger, L; Denison, M S; V ... | P42ES004699, R01ES007685 | Toxicol Sci (2006 Jul) |
16601081
|
2006 |
| Comparison of recombinant cell bioassays for the detection of Ah receptor agonists. | Han, Dalho; Nagy, Scott R; Denison, Michael S | P42ES004699, R01ES007685 | Biofactors (2004) |
15096657
|
2004 |
| Activation of the Ah receptor by extracts of dietary herbal supplements, vegetables, and fruits. | Jeuken, Anoek; Keser, Bart J G; Khan, Elaine; Brouwer, Abraham; Koeman, Jan; Denison, Michael ... | P42ES004699, P42ES004911, R01ES007685 | J Agric Food Chem (2003 Aug 27) |
12926901
|
2003 |
| Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemica ... | Denison, Michael S; Nagy, Scott R | P42ES004699, R01ES007685, T32ES007059 | Annu Rev Pharmacol Toxicol (2003) |
12540743
|
2003 |
| Analysis of the antiestrogenic activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in human ovarian carc ... | Rogers, Jane M; Denison, Michael S | P42ES004699, R01ES007685 | Mol Pharmacol (2002 Jun) |
12021401
|
2002 |
| Application of the luciferase cell culture bioassay for the detection of refined petroleum products. | Ziccardi, Michael H; Gardner, Ian A; Mazet, Jonna A K; Denison, Michael S | P42ES004699, R01ES007685 | Mar Pollut Bull (2002 Oct) |
12474956
|
2002 |
| Application of the luciferase recombinant cell culture bioassay system for the analysis of polycycli ... | Ziccardi, Michael H; Gardner, Ian A; Denison, Michael S | P42ES004699, R01ES007685 | Environ Toxicol Chem (2002 Oct) |
12371477
|
2002 |
| Development of a green fluorescent protein-based cell bioassay for the rapid and inexpensive detecti ... | Nagy, Scott R; Sanborn, James R; Hammock, Bruce D; Denison, Michael S | P42ES004699, R01ES007685, T32ES007059 | Toxicol Sci (2002 Feb) |
11812924
|
2002 |
| Identification of novel Ah receptor agonists using a high-throughput green fluorescent protein-based ... | Nagy, Scott R; Liu, Gang; Lam, Kit S; Denison, Michael S | P42ES004699, R01ES007685, T32ES007059 | Biochemistry (2002 Jan 22) |
11790108
|
2002 |
| Ligand binding and activation of the Ah receptor. | Denison, Michael S; Pandini, Alessandro; Nagy, Scott R; Baldwin, Enoch P; Bonati, Laura | R01ES007685, T32ES007059 | Chem Biol Interact (2002 Sep 20) |
12213382
|
2002 |
| The silencing mediator of retinoic acid and thyroid hormone receptors can interact with the aryl hyd ... | Rushing, S Renée; Denison, Michael S | P42ES004699, R01ES007685 | Arch Biochem Biophys (2002 Jul 15) |
12139968
|
2002 |
| Activation of the Ah receptor signaling pathway by prostaglandins. | Seidel, S D; Winters, G M; Rogers, W J; Ziccardi, M H; Li, V; Keser, B; Denison, M S | P42ES004699, R01ES007685, T32ES007059 | J Biochem Mol Toxicol (2001) |
11673847
|
2001 |
| Comparative studies on the effects of green tea extracts and individual tea catechins on human CYP1A ... | Williams, S N; Shih, H; Guenette, D K; Brackney, W; Denison, M S; Pickwell, G V; Quattrochi, ... | P42ES004699, R01ES007685 | Chem Biol Interact (2000 Nov 01) |
11064004
|
2000 |
| Development and modification of a recombinant cell bioassay to directly detect halogenated and polyc ... | Ziccardi, M H; Gardner, I A; Denison, M S | P42ES004699, R01ES007685 | Toxicol Sci (2000 Mar) |
10746945
|
2000 |
| Recombinant cell bioassays for endocrine disruptors: development of a stably transfected human ovari ... | Rogers, J M; Denison, M S | P42ES004699, R01ES007685 | In Vitr Mol Toxicol (2000) |
10900408
|
2000 |
| Activation of the Ah receptor by tryptophan and tryptophan metabolites. | Heath-Pagliuso, S; Rogers, W J; Tullis, K; Seidel, S D; Cenijn, P H; Brouwer, A; Denison, M S | P42ES004699, R01ES007685 | Biochemistry (1998 Aug 18) |
9708986
|
1998 |
| Activation of the Ah receptor signal transduction pathway by bilirubin and biliverdin. | Phelan, D; Winter, G M; Rogers, W J; Lam, J C; Denison, M S | P42ES004699, R01ES007685 | Arch Biochem Biophys (1998 Sep 1) |
9721195
|
1998 |
| Carbaryl, a carbamate insecticide, is a ligand for the hepatic Ah (dioxin) receptor. | Denison, M S; Phelan, D; Winter, G M; Ziccardi, M H | P42ES004699, R01ES007685 | Toxicol Appl Pharmacol (1998 Oct) |
9853009
|
1998 |
| The Ah receptor: a regulator of the biochemical and toxicological actions of structurally diverse ch ... | Denison, M S; Heath-Pagliuso, S | R01ES007685 | Bull Environ Contam Toxicol (1998 Nov) |
9841714
|
1998 |
| Brevetoxin-6 (PbTx-6), a nonaromatic marine neurotoxin, is a ligand of the aryl hydrocarbon receptor ... | Washburn, B S; Rein, K S; Baden, D G; Walsh, P J; Hinton, D E; Tullis, K; Denison, M S | R01ES007685 | Arch Biochem Biophys (1997 Jul 15) |
9224724
|
1997 |