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Who We Fund: Publication Detail

Project Title: MECHANISMS OF MANGANESE NEUROTOXICITY
PI: Bowman, Aaron B
Institution: Purdue University
Grant Number: R01ES010563

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Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Anandamide and WIN 55212-2 Afford Protection in Rat Brain Mitochondria in a Toxic Model Induced by 3 ...   Maya-López, Marisol; Monsalvo-Maraver, Luis Angel; Delgado-Arzate, Ana Laura; Olivera-Pérez, Car ... R01ES007331, R01ES010563 Mol Neurobiol (2024 Feb 03) 38307967 Exiting the NIEHS site 2024 
Interactions Between the Ubiquitin-Proteasome System, Nrf2, and the Cannabinoidome as Protective Str ...   Monsalvo-Maraver, Luis Angel; Ovalle-Noguez, Enid A; Nava-Osorio, Jade; Maya-López, Marisol; Ran ... R01ES010563 Neurotox Res (2024 Feb 23) 38393521 Exiting the NIEHS site 2024 
Should ebselen be considered for the treatment of mercury intoxication? A minireview.   Barbosa, Nilda V; Aschner, Michael; Tinkov, Alexey A; Farina, Marcelo; Rocha, João Batista Teix ... R01ES007331, R01ES010563 Toxicol Mech Methods (2024 Jan) 37731353 Exiting the NIEHS site 2024 
A Reliable Method Based on Liquid Chromatography-Tandem Mass Spectrometry for the Simultaneous Quant ...   Weishaupt, Ann-Kathrin; Kubens, Laura; Ruecker, Lysann; Schwerdtle, Tanja; Aschner, Michael; Bo ... R01ES007331, R01ES010563 Molecules (2023 Jul 13) 37513246 Exiting the NIEHS site 2023 
Amyloid Beta Peptide-Mediated Alterations in Mitochondrial Dynamics and its Implications for Alzheim ...   Monsalvo-Maraver, Luis Ángel; Maya-López, Marisol; Rangel-López, Edgar; Túnez, Isaac; Tinkov, A ... R01ES007331, R01ES010563 CNS Neurol Disord Drug Targets (2023) 35713133 Exiting the NIEHS site 2023 
Association between Heavy Metals, Metalloids and Metabolic Syndrome: New Insights and Approaches.   Martins, Airton C; Ferrer, Beatriz; Tinkov, Alexey A; Caito, Samuel; Deza-Ponzio, Romina; Skaln ... R01ES007331, R01ES010563 Toxics (2023 Aug 03) 37624175 Exiting the NIEHS site 2023 
Astrocytic Yin Yang 1 is critical for murine brain development and protection against apoptosis, oxi ...   Pajarillo, Edward; Nyarko-Danquah, Ivan; Digman, Alexis; Vied, Cynthia; Son, Deok-Soo; Lee, Ja ... R01ES007331, R01ES010563, R01ES031282 Glia (2023 Feb) 36300569 Exiting the NIEHS site 2023 
Butyrate Protects and Synergizes with Nicotine against Iron- and Manganese-induced Toxicities in Cel ...   Tizabi, Yousef; Getachew, Bruk; Aschner, Michael R01ES010563 Neurotox Res (2023 Dec 14) 38095760 Exiting the NIEHS site 2023 
Butyrate protects and synergizes with nicotine against iron- and manganese-induced toxicities in cel ...   Tizabi, Yousef; Getachew, Bruk; Aschner, Michael R01ES007331, R01ES010563 Res Sq (2023 Oct 05) 37886507 Exiting the NIEHS site 2023 
Cobalt nanoparticles induce mitochondrial damage and β-amyloid toxicity via the generation of reacti ...   Chen, Jingrong; Chen, Cheng; Wang, Na; Wang, Chunyu; Gong, Zhaohui; Du, Jingxian; Lai, Hongli ... R01ES007331, R01ES010563 Neurotoxicology (2023 Mar) 36716931 Exiting the NIEHS site 2023 
COVID-19 vaccination and case fatality rates: a case report in a Brazilian municipality.   Paludetto Junior, Moacir; Olak, André S; Passarelli-Araujo, Hisrael; Susuki, Aline M; Aschner, ... R01ES010563 Cad Saude Publica (2023) 37018770 Exiting the NIEHS site 2023 
Dopaminergic modulation by quercetin: In silico and in vivo evidence using Caenorhabditis elegans as ...   Salgueiro, Willian Goulart; Soares, Marcell Valandro; Martins, Cassiano Fiad; Paula, Fávero Reis ... R01ES007331, R01ES010563 Chem Biol Interact (2023 Sep 01) 37348670 Exiting the NIEHS site 2023 
Evaluation of neurotoxicity and the role of oxidative stress of cobalt nanoparticles, titanium dioxi ...   Chen, Cheng; Chen, Jingrong; Lin, Xinpei; Yang, Jiafu; Qu, Huimin; Li, Lisong; Zhang, Duanyan ... R01ES007331, R01ES010563 Toxicol Sci (2023 Oct 30) 37584706 Exiting the NIEHS site 2023 
Genetic factors in methylmercury-induced neurotoxicity: What have we learned from Caenorhabditis ele ...   Ke, Tao; Junior, Fernando Barbosa; Santamaria, Abel; Bowman, Aaron B; Aschner, Michael R01ES007331, R01ES010563 Adv Neurotoxicol (2023) 37389202 Exiting the NIEHS site 2023 
Identification of the bacterial metabolite aerugine as potential trigger of human dopaminergic neuro ...   Ückert, Anna-Katharina; Rütschlin, Sina; Gutbier, Simon; Wörz, Nathalie Christine; Miah, Mahfuz ... R01ES007331, R01ES010563 Environ Int (2023 Oct) 37797477 Exiting the NIEHS site 2023 
IGF/mTORC1/S6 Signaling Is Potentiated and Prolonged by Acute Loading of Subtoxicological Manganese ...   Tang, Xueqi; Balachandran, Rekha C; Aschner, Michael; Bowman, Aaron B R01ES010563 Biomolecules (2023 Aug 08) 37627294 Exiting the NIEHS site 2023 
Interaction of Heavy Metal Lead with Gut Microbiota: Implications for Autism Spectrum Disorder.   Tizabi, Yousef; Bennani, Samia; El Kouhen, Nacer; Getachew, Bruk; Aschner, Michael R01ES007331, R01ES010563 Biomolecules (2023 Oct 19) 37892231 Exiting the NIEHS site 2023 
MiR-130/SNAP-25 axis regulate presynaptic alteration in anterior cingulate cortex involved in lead i ...   Wang, Tao; Guan, Rui-Li; Zou, Yun-Feng; Zheng, Gang; Shen, Xue-Feng; Cao, Zi-Peng; Yang, Rui- ... R01ES007331, R01ES010563 J Hazard Mater (2023 Feb 05) 36332276 Exiting the NIEHS site 2023 
Mitochondria in the Spotlight: C. elegans as a Model Organism to Evaluate Xenobiotic-Induced Dysfunc ...   Martins, Airton C; Virgolini, Miriam B; Ávila, Daiana Silva; Scharf, Pablo; Li, Jung; Tinkov, ... R01ES007331, R01ES010563 Cells (2023 Aug 22) 37681856 Exiting the NIEHS site 2023 
Morphological alterations in C57BL/6 mouse intestinal organoids as a tool for predicting chemical-in ...   Wang, Ziwei; Chen, Shen; Pang, Yaqin; Ye, Lizhu; Zhang, Qi; Jiang, Xinhang; Zhang, Rui; Li, ... R01ES007331, R01ES010563 Arch Toxicol (2023 Apr) 36806895 Exiting the NIEHS site 2023 
Nauphoeta cinerea as an emerging model in neurotoxicology.   Adedara, Isaac A; Mohammed, Khadija A; Canzian, Julia; Rosemberg, Denis B; Aschner, Michael; Fa ... R01ES007331, R01ES010563 Adv Neurotoxicol (2023) 37389201 Exiting the NIEHS site 2023 
Neurotoxicology of metals and metallic nanoparticles in Caenorhabditis elegans.   Agarrayua, Danielle Araujo; Silva, Aline Castro; Saraiva, Nariani Rocha; Soares, Ana Thalita; As ... R01ES007331, R01ES010563 Adv Neurotoxicol (2023) 37384197 Exiting the NIEHS site 2023 
Perspective on halogenated organic compounds.   Kodavanti, Prasada Rao S; Costa, Lucio G; Aschner, Michael R01ES010563 Adv Neurotoxicol (2023) 37920427 Exiting the NIEHS site 2023 
Role of Astrocytes in Parkinson's Disease Associated with Genetic Mutations and Neurotoxicants.   Kim, Sanghoon; Pajarillo, Edward; Nyarko-Danquah, Ivan; Aschner, Michael; Lee, Eunsook R01ES010563, R01ES031282 Cells (2023 Feb 15) 36831289 Exiting the NIEHS site 2023 
Signaling Pathways Involved in Manganese-Induced Neurotoxicity.   Cheng, Hong; Villahoz, Beatriz Ferrer; Ponzio, Romina Deza; Aschner, Michael; Chen, Pan R01ES010563 Cells (2023 Dec 14) 38132161 Exiting the NIEHS site 2023 
Therapeutic m6A Eraser ALKBH5 mRNA-Loaded Exosome-Liposome Hybrid Nanoparticles Inhibit Progression ...   Wu, Shenshen; Yun, Jun; Tang, Weiyan; Familiari, Giuseppe; Relucenti, Michela; Wu, Jiong; Li, ... R01ES007331, R01ES010563 ACS Nano (2023 Jun 27) 37310898 Exiting the NIEHS site 2023 
Type 1 diabetes and diet-induced obesity predispose C57BL/6J mice to PM2.5-induced lung injury: a co ...   Chen, Shen; Li, Miao; Zhang, Rui; Ye, Lizhu; Jiang, Yue; Jiang, Xinhang; Peng, Hui; Wang, Zi ... R01ES007331, R01ES010563 Part Fibre Toxicol (2023 Apr 17) 37069663 Exiting the NIEHS site 2023 
An Update on the Critical Role of α-Synuclein in Parkinson's Disease and Other Synucleinopathies: fr ...   Serratos, Iris N; Hernández-Pérez, Elizabeth; Campos, Carolina; Aschner, Michael; Santamaría, A ... R01ES010563 Mol Neurobiol (2022 Jan) 34750787 Exiting the NIEHS site 2022 
Chemotherapeutic Risk lncRNA-PVT1 SNP Sensitizes Metastatic Colorectal Cancer to FOLFOX Regimen.   Wu, Shenshen; Yang, Xi; Tang, Weiyan; Familiari, Giuseppe; Relucenti, Michela; Aschner, Michae ... R01ES007331, R01ES010563 Front Oncol (2022) 35433465 Exiting the NIEHS site 2022 
CpG site-specific methylation as epi-biomarkers for the prediction of health risk in PAHs-exposed po ...   Ye, Lizhu; He, Zhini; Li, Daochuan; Chen, Liping; Chen, Shen; Guo, Ping; Yu, Dianke; Ma, Lu; ... R01ES007331, R01ES010563 J Hazard Mater (2022 Jun 05) 35231813 Exiting the NIEHS site 2022 
Determination of tipping point in course of PM2.5 organic extracts-induced malignant transformation ...   Chen, Shen; Li, Daochuan; Yu, Dianke; Li, Miao; Ye, Lizhu; Jiang, Yue; Tang, Shijie; Zhang, ... R01ES007331, R01ES010563 J Hazard Mater (2022 Mar 15) 34933256 Exiting the NIEHS site 2022 
Effects of co-exposure to lead and manganese on learning and memory deficits.   Guan, Ruili; Wang, Tao; Dong, Xiaoru; Du, Kejun; Li, Juan; Zhao, Fang; Xu, Jie; Li, Bin; Zhe ... R01ES010563 J Environ Sci (China) (2022 Nov) 35654517 Exiting the NIEHS site 2022 
Epstein-Barr Virus-Encoded MicroRNA-BART18-3p Promotes Colorectal Cancer Progression by Targeting De ...   Meng, Qingtao; Sun, Hao; Wu, Shenshen; Familiari, Giuseppe; Relucenti, Michela; Aschner, Micha ... R01ES007331, R01ES010563 Adv Sci (Weinh) (2022 Dec) 36307872 Exiting the NIEHS site 2022 
Erratum for Chen et al. Perturbation of specific signaling pathways is involved in initiation of mou ...   R01ES007331, R01ES010563 Hepatology (2022 May) 35318702 Exiting the NIEHS site 2022 
Exposing the role of metals in neurological disorders: a focus on manganese.   Kim, Hyunjin; Harrison, Fiona E; Aschner, Michael; Bowman, Aaron B R01ES007331, R01ES010563, R01ES031401 Trends Mol Med (2022 Jul) 35610122 Exiting the NIEHS site 2022 
Genomic, transcriptomic, and metabolomic profiles of hiPSC-derived dopamine neurons from clinically ...   Cukier, Holly N; Kim, Hyunjin; Griswold, Anthony J; Codreanu, Simona G; Prince, Lisa M; Sherrod ... R01ES010563 NPJ Parkinsons Dis (2022 Jun 29) 35768426 Exiting the NIEHS site 2022 
Hydrogen Sulfide (H2S) Signaling as a Protective Mechanism against Endogenous and Exogenous Neurotox ...   Aschner, Michael; Skalny, Anatoly V; Ke, Tao; da Rocha, Joao Bt; Paoliello, Monica Mb; Santamar ... R01ES010563 Curr Neuropharmacol (2022) 35236265 Exiting the NIEHS site 2022 
Iron overload and neurodegenerative diseases: What can we learn from Caenorhabditis elegans?   Martins, Airton C; Virgolini, Miriam B; Tinkov, Alexey A; Skalny, Anatoly V; Tirumala, Rohan P; ... R01ES007331, R01ES010563 Toxicol Res Appl (2022) 35990536 Exiting the NIEHS site 2022 
Manganese phosphorylates Yin Yang 1 at serine residues to repress EAAT2 in human H4 astrocytes.   Rizor, Asha; Pajarillo, Edward; Son, Deok-Soo; Aschner, Michael; Lee, Eunsook R01ES007331, R01ES010563, R01ES031282 Toxicol Lett (2022 Feb 01) 34800614 Exiting the NIEHS site 2022 
Manganese-induced hyperactivity and dopaminergic dysfunction depend on age, sex and YAC128 genotype.   Wilcox, Jordyn M; Consoli, David C; Paffenroth, Krista C; Spitznagel, Brittany D; Calipari, Eri ... R01ES010563, R01ES031401 Pharmacol Biochem Behav (2022 Feb) 35063467 Exiting the NIEHS site 2022 
Meteorological parameters and cases of COVID-19 in Brazilian cities: an observational study.   Olak, André S; Santos, Willian S; Susuki, Aline M; Pott-Junior, Henrique; V Skalny, Anatoly; Ti ... R01ES007331, R01ES010563 J Toxicol Environ Health A (2022 01 02) 34474657 Exiting the NIEHS site 2022 
Methylcyclopentadienyl Manganese Tricarbonyl Alter Behavior and Cause Ultrastructural Changes in the ...   Zhu, Qi-Feng; Lu, Li-Li; Fang, Yuan-Yuan; Wu, Jie; Huang, Zhao-Ying; Zheng, Xiao-Wei; Song, H ... R01ES010563 Neurochem Res (2022 Aug) 35513760 Exiting the NIEHS site 2022 
Neurotoxicity Evaluation of Nanomaterials Using C. elegans: Survival, Locomotion Behaviors, and Oxid ...   Zheng, Fuli; Chen, Cheng; Aschner, Michael R01ES007331, R01ES010563 Curr Protoc (2022 Jul) 35849041 Exiting the NIEHS site 2022 
PP2A-mTOR-p70S6K/4E-BP1 axis regulates M1 polarization of pulmonary macrophages and promotes ambient ...   Chen, Shen; Chen, Liping; Ye, Lizhu; Jiang, Yue; Li, Qiong; Zhang, Haiyan; Zhang, Rui; Li, H ... R01ES007331, R01ES010563 J Hazard Mater (2022 02 15) 34740159 Exiting the NIEHS site 2022 
Prediction of COPD acute exacerbation in response to air pollution using exosomal circRNA profile an ...   Meng, Qingtao; Wang, Jiajia; Cui, Jian; Li, Bin; Wu, Shenshen; Yun, Jun; Aschner, Michael; Wa ... R01ES007331, R01ES010563 Environ Int (2022 Oct) 36041244 Exiting the NIEHS site 2022 
Probiotics and the Treatment of Parkinson's Disease: An Update.   Mirzaei, Hamed; Sedighi, Saman; Kouchaki, Ebrahim; Barati, Erfaneh; Dadgostar, Ehsan; Aschner, ... R01ES007331, R01ES010563 Cell Mol Neurobiol (2022 Nov) 34283340 Exiting the NIEHS site 2022 
Protein phosphatase 2A regulates cytotoxicity and drug resistance by dephosphorylating AHR and MDR1.   Chen, Liping; Guo, Ping; Li, Wenxue; Jiang, Xinhang; Zhao, Qun; Li, Daochuan; Wang, Qing; Xia ... R01ES007331, R01ES010563 J Biol Chem (2022 May) 35405096 Exiting the NIEHS site 2022 
Sex-dependent metal accumulation and immunoexpression of Hsp70 and Nrf2 in rats' brain following man ...   Ijomone, Omamuyovwi M; Iroegbu, Joy D; Morcillo, Patricia; Ayodele, Akinyemi J; Ijomone, Olayem ... R01ES007331, R01ES010563 Environ Toxicol (2022 Sep) 35596948 Exiting the NIEHS site 2022 
Single-cell transcriptomics reveals immune dysregulation mediated by IL-17A in initiation of chronic ...   Zhang, Rui; Chen, Shen; Chen, Liping; Ye, Lizhu; Jiang, Yue; Peng, Hui; Guo, Zhanyu; Li, Mia ... R01ES007331, R01ES010563 Part Fibre Toxicol (2022 Jun 23) 35739565 Exiting the NIEHS site 2022 
Sodium para-aminosalicylic acid ameliorates lead-induced hippocampal neuronal apoptosis by suppressi ...   Li, Zhao-Cong; Wang, Lei-Lei; Zhao, Yue-Song; Peng, Dong-Jie; Chen, Jing; Jiang, Si-Yang; Zhao ... R01ES010563 Ecotoxicol Environ Saf (2022 Aug) 36068756 Exiting the NIEHS site 2022 
Thallium Induces Antiproliferative and Cytotoxic Activity in Glioblastoma C6 and U373 Cell Cultures ...   Rangel-López, Edgar; Robles-Bañuelos, Benjamín; Guadiana-Ramírez, Natalia; Alvarez-Garduño, Vale ... R01ES010563 Neurotox Res (2022 Jun) 35476314 Exiting the NIEHS site 2022 
Toxic metals that interact with thiol groups and alteration in insect behavior.   Oliveira, Cláudia S; Nogara, Pablo A; Lima, Luíza S; Galiciolli, Maria Ea; Souza, Júlia V; Asch ... R01ES007331, R01ES010563 Curr Opin Insect Sci (2022 Aug) 35462063 Exiting the NIEHS site 2022 
3,3'-diindolylmethane exerts antiproliferation and apoptosis induction by TRAF2-p38 axis in gastric ...   Ye, Yang; Ye, Fen; Li, Xue; Yang, Qi; Zhou, Jianwei; Xu, Wenrong; Aschner, Michael; Lu, Rong ... R01ES007331, R01ES010563 Anticancer Drugs (2021 Feb 01) 33315588 Exiting the NIEHS site 2021 
A bistable, multiport valve enables microformulators creating microclinical analyzers that reveal ab ...   Miller, Dusty R; Schaffer, David K; Neely, M Diana; McClain, Ethan S; Travis, Adam R; Block 3rd ... R01ES007331, R01ES010563, T32ES007028 Sens Actuators B Chem (2021 Aug 15) 34092923 Exiting the NIEHS site 2021 
A potential role for zinc in restless legs syndrome.   Chen, Pan; Bornhorst, Julia; Patton, Stephanie; Bagai, Kanika; Nitin, Rachana; Miah, Mahfuzur; ... R01ES007331, R01ES010563 Sleep (2021 Apr 09) 33175142 Exiting the NIEHS site 2021 
An updated systematic review on the association between Cd exposure, blood pressure and hypertension ...   Martins, Airton C; Almeida Lopes, Ana Carolina B; Urbano, Mariana R; Carvalho, Maria de Fatima H ... R01ES007331, R01ES010563 Ecotoxicol Environ Saf (2021 Jan 15) 33396156 Exiting the NIEHS site 2021 
Application of Fluorescence Microscopy and Behavioral Assays to Demonstrating Neuronal Connectomes a ...   Ijomone, Omamuyovwi M; Gubert, Priscila; Okoh, Comfort O A; Varão, Alexandre M; Amara, Leandro ... R01ES007331, R01ES010563 Neuromethods (2021) 34754139 Exiting the NIEHS site 2021 
Caenorhabditis elegans as a model for studies on quinolinic acid-induced NMDAR-dependent glutamaterg ...   Limana da Silveira, Tássia; Lopes Machado, Marina; Bicca Obetine Baptista, Fabiane; Farina Gonçal ... R01ES007331, R01ES010563 Brain Res Bull (2021 10) 34271120 Exiting the NIEHS site 2021 
Commonalities between Copper Neurotoxicity and Alzheimer's Disease.   Patel, Roshni; Aschner, Michael R01ES007331, R01ES010563 Toxics (2021 Jan 07) 33430181 Exiting the NIEHS site 2021 
Conjugates of desferrioxamine and aromatic amines improve markers of iron-dependent neurotoxicity.   Carvalho, Rodrigo R V; Peres, Tanara V; Liria, Cleber W; Machini, M Teresa; Aschner, Michael; E ... R01ES007331, R01ES010563 Biometals (2021 04) 33389339 Exiting the NIEHS site 2021 
Copper, Iron, Selenium and Lipo-Glycemic Dysmetabolism in Alzheimer's Disease.   Aaseth, Jan; Skalny, Anatoly V; Roos, Per M; Alexander, Jan; Aschner, Michael; Tinkov, Alexey ... R01ES007331, R01ES010563 Int J Mol Sci (2021 Aug 31) 34502369 Exiting the NIEHS site 2021 
Corrigendum to "Toxic metal exposure as a possible risk factor for COVID-19 and other respiratory in ...   Skalny, Anatoly V; Lima, Thania Rios Rossi; Ke, Tao; Zhou, Ji-Chang; Bornhorst, Julia; Alekseen ... R01ES007331, R01ES010563 Food Chem Toxicol (2021 Mar) 33500155 Exiting the NIEHS site 2021 
Defective Mitochondrial Dynamics Underlie Manganese-Induced Neurotoxicity.   Morcillo, Patricia; Cordero, Hector; Ijomone, Omamuyovwi M; Ayodele, Akinyemi; Bornhorst, Julia ... R01ES010563 Mol Neurobiol (2021 Jul) 33666854 Exiting the NIEHS site 2021 
Diterpene glycosides from Holothuria scabra exert the α-synuclein degradation and neuroprotection ag ...   Chalorak, Pawanrat; Sornkaew, Nilubon; Manohong, Preeyanuch; Niamnont, Nakorn; Malaiwong, Nawap ... R01ES007331, R01ES010563 J Ethnopharmacol (2021 Oct 28) 34147616 Exiting the NIEHS site 2021 
Endocrine-disrupting activity of mancozeb.   Skalny, Anatoly; Aschner, Michael; Paoliello, Monica; Santamaria, Abel; Nikitina, Natalia; Rejn ... R01ES010563 Arh Farm (Belgr) (2021) 35990020 Exiting the NIEHS site 2021 
Endothelial Dysfunction Induced by Cadmium and Mercury and its Relationship to Hypertension.   Martins, Airton C; Santos, Alessanda A D; Lopes, Ana C B A; Skalny, Anatoly V; Aschner, Michael ... R01ES007331, R01ES010563 Curr Hypertens Rev (2021) 33475076 Exiting the NIEHS site 2021 
Evaluating the risk of manganese-induced neurotoxicity of parenteral nutrition: review of the curren ...   Martins Jr, Airton C; Ruella Oliveira, Silvana; Barbosa Jr, Fernando; Tinkov, Alexey A; V Skalny ... R01ES007331, R01ES010563, R01ES031282 Expert Opin Drug Metab Toxicol (2021 May) 33620266 Exiting the NIEHS site 2021 
Haloperidol Interactions with the dop-3 Receptor in Caenorhabditis elegans.   Krum, Bárbara Nunes; Martins Jr, Airton C; Queirós, Libânia; Ferrer, Beatriz; Milne, Ginger L; ... R01ES007331, R01ES010563 Mol Neurobiol (2021 Jan) 32935232 Exiting the NIEHS site 2021 
HER2-specific chimeric antigen receptor-T cells for targeted therapy of metastatic colorectal cancer ...   Xu, Jie; Meng, Qingtao; Sun, Hao; Zhang, Xinwei; Yun, Jun; Li, Bin; Wu, Shenshen; Li, Xiaobo ... R01ES007331, R01ES010563 Cell Death Dis (2021 Nov 27) 34839348 Exiting the NIEHS site 2021 
Hypoxia-Inducible Exosomes Facilitate Liver-Tropic Premetastatic Niche in Colorectal Cancer.   Sun, Hao; Meng, Qingtao; Shi, Chengyu; Yang, Hongbao; Li, Xiaobo; Wu, Shenshen; Familiari, Gi ... R01ES007331, R01ES010563 Hepatology (2021 11) 34110633 Exiting the NIEHS site 2021 
Identification of Three Small Molecules That Can Selectively Influence Cellular Manganese Levels in ...   Horning, Kyle J; Tang, Xueqi; Thomas, Morgan G; Aschner, Michael; Bowman, Aaron B R01ES010563, T32ES007028 Molecules (2021 Feb 22) 33671818 Exiting the NIEHS site 2021 
Impact of environmental toxicants on p38- and ERK-MAPK signaling pathways in the central nervous sys ...   Ijomone, Omamuyovwi M; Iroegbu, Joy D; Aschner, Michael; Bornhorst, Julia R01ES007331, R01ES010563 Neurotoxicology (2021 Sep) 34389354 Exiting the NIEHS site 2021 
In silico Studies on the Interaction between Mpro and PLpro From SARS-CoV-2 and Ebselen, its Metabol ...   Nogara, Pablo Andrei; Omage, Folorunsho Bright; Bolzan, Gustavo Roni; Delgado, Cássia Pereira; A ... R01ES007331, R01ES010563 Mol Inform (2021 08) 34018687 Exiting the NIEHS site 2021 
Intercellular transfer of mitochondria via tunneling nanotubes protects against cobalt nanoparticle- ...   Zheng, Fuli; Luo, Zhousong; Lin, Xinpei; Wang, Wei; Aschner, Michael; Cai, Ping; Wang, Yuan-L ... R01ES007331, R01ES010563 Nanotoxicology (2021 Dec) 35077651 Exiting the NIEHS site 2021 
lncRNA TUG1 as a ceRNA promotes PM exposure-induced airway hyper-reactivity.   Li, Bin; Huang, Nannan; Wei, Shengnan; Xv, Jie; Meng, Qingtao; Aschner, Michael; Li, Xiaobo; ... R01ES007331, R01ES010563 J Hazard Mater (2021 08 15) 34492818 Exiting the NIEHS site 2021 
Manganese-induced reactive oxygen species activate IκB kinase to upregulate YY1 and impair glutamate ...   Rizor, Asha; Pajarillo, Edward; Nyarko-Danquah, Ivan; Digman, Alexis; Mooneyham, Leyah; Son, D ... R01ES010563, R01ES031282 Neurotoxicology (2021 09) 34310962 Exiting the NIEHS site 2021 
Measurement of the Effects of Metals on Taxis-to-Food Behavior in Caenorhabditis elegans.   Queirós, Libânia; Monteiro, Luana; Marques, Carlos; Pereira, Joana L; Gonçalves, Fernando J M; ... R01ES007331, R01ES010563 Curr Protoc (2021 May) 33974358 Exiting the NIEHS site 2021 
Mechanisms of Metal-Induced Mitochondrial Dysfunction in Neurological Disorders.   Cheng, Hong; Yang, Bobo; Ke, Tao; Li, Shaojun; Yang, Xiaobo; Aschner, Michael; Chen, Pan R01ES007331, R01ES010563 Toxics (2021 Jun 17) 34204190 Exiting the NIEHS site 2021 
Molecular mechanisms of aluminum neurotoxicity: Update on adverse effects and therapeutic strategies ...   Skalny, Anatoly V; Aschner, Michael; Jiang, Yueming; Gluhcheva, Yordanka G; Tizabi, Yousef; Lob ... R01ES007331, R01ES010563 Adv Neurotoxicol (2021) 34263089 Exiting the NIEHS site 2021 
MOLECULAR MECHANISMS OF LEAD NEUROTOXICITY.   Virgolini, Miriam B; Aschner, Michael R01ES007331, R01ES010563 Adv Neurotoxicol (2021) 34263090 Exiting the NIEHS site 2021 
Molecular Targets of Manganese-Induced Neurotoxicity: A Five-Year Update.   Tinkov, Alexey A; Paoliello, Monica M B; Mazilina, Aksana N; Skalny, Anatoly V; Martins, Airton ... R01ES010563 Int J Mol Sci (2021 Apr 28) 33925013 Exiting the NIEHS site 2021 
Multibiomarker approach to assess the magnitude of occupational exposure and effects induced by a mi ...   Lopes de Andrade, V; Serrazina, D; Mateus, M L; Batoréu, C; Aschner, M; Marreilha Dos Santos, ... R01ES007331, R01ES010563 Toxicol Appl Pharmacol (2021 10 15) 34437931 Exiting the NIEHS site 2021 
Neurotoxicity mechanisms of manganese in the central nervous system.   Pajarillo, Edward; Nyarko-Danquah, Ivan; Adinew, Getinet; Rizor, Asha; Aschner, Michael; Lee, ... R01ES007331, R01ES010563 Adv Neurotoxicol (2021) 34263091 Exiting the NIEHS site 2021 
NEUROTOXICITY OF METAL MIXTURES.   Lopes de Andrade, Vanda; Marreilha Dos Santos, Ana Paula; Aschner, Michael R01ES007331, R01ES010563 Adv Neurotoxicol (2021) 34263093 Exiting the NIEHS site 2021 
New epigenetic players in stroke pathogenesis: From non-coding RNAs to exosomal non-coding RNAs.   Mahjoubin-Tehran, Maryam; Rezaei, Samaneh; Jesmani, Amin; Birang, Nafise; Morshedi, Korosh; Kha ... R01ES007331, R01ES010563 Biomed Pharmacother (2021 Aug) 34044272 Exiting the NIEHS site 2021 
New insights on mechanisms underlying methylmercury-induced and manganese-induced neurotoxicity.   Martins, Airton C; Ke, Tao; Bowman, Aaron B; Aschner, Michael R01ES007331, R01ES010563 Curr Opin Toxicol (2021 Mar) 33898886 Exiting the NIEHS site 2021 
Novel Pharmacotherapies in Parkinson's Disease.   Tizabi, Yousef; Getachew, Bruk; Aschner, Michael R01ES007331, R01ES010563 Neurotox Res (2021 Aug) 34003454 Exiting the NIEHS site 2021 
Nutritive Manganese and Zinc Overdosing in Aging C. elegans Result in a Metallothionein-Mediated Alt ...   Baesler, Jessica; Michaelis, Vivien; Stiboller, Michael; Haase, Hajo; Aschner, Michael; Schwerd ... R01ES007331, R01ES010563 Mol Nutr Food Res (2021 Apr) 33641237 Exiting the NIEHS site 2021 
On the Biomedical Properties of Endocannabinoid Degradation and Reuptake Inhibitors: Pre-clinical an ...   Paredes-Ruiz, Karen Jaqueline; Chavira-Ramos, Karla; Orozco-Morales, Mario; Karasu, Cimen; Tinko ... R01ES010563 Neurotox Res (2021 Dec) 34741755 Exiting the NIEHS site 2021 
Overview of Chemotaxis Behavior Assays in Caenorhabditis elegans.   Queirós, Libânia; Marques, Carlos; Pereira, Joana L; Gonçalves, Fernando J M; Aschner, Michael; ... R01ES007331, R01ES010563 Curr Protoc (2021 May) 33974354 Exiting the NIEHS site 2021 
Pain Perception and Management: Where do We Stand?   Afridi, Bilal; Khan, Haroon; Akkol, Esra K; Aschner, Michael R01ES007331, R01ES010563 Curr Mol Pharmacol (2021) 32525788 Exiting the NIEHS site 2021 
Perturbation of Specific Signaling Pathways Is Involved in Initiation of Mouse Liver Fibrosis.   Chen, Liping; Guo, Ping; Li, Wenxue; Fang, Fei; Zhu, Wei; Fan, Junling; Wang, Fangping; Gao, ... R01ES007331, R01ES010563 Hepatology (2021 04) 32654205 Exiting the NIEHS site 2021 
Perturbed MAPK signaling in ASD: Impact of metal neurotoxicity.   Aluko, Oritoke M; Lawal, Saheed A; Ijomone, Omamuyovwi M; Aschner, Michael R01ES007331, R01ES010563 Curr Opin Toxicol (2021 Jun) 34263087 Exiting the NIEHS site 2021 
Platinum nanoparticles Protect Against Lipopolysaccharide-Induced Inflammation in Microglial BV-2 Ce ...   Elmazoglu, Zubeyir; Kayhan, Handan; Santamaría, Abel; Rangel-López, Edgar; Uğur, Pelin Kelicen; ... R01ES007331, R01ES010563 Neurochem Res (2021 Dec) 34432181 Exiting the NIEHS site 2021 
Plumbagin attenuates traumatic tracheal stenosis in rats and inhibits lung fibroblast proliferation ...   Shi, Wei; Fang, Yuanyuan; Jiang, Yueming; Jiang, Siyang; Li, Yu; Li, Wentao; Xu, Mingpeng; As ... R01ES007331, R01ES010563 Bioengineered (2021 12) 34304701 Exiting the NIEHS site 2021 
Protective Effects of Novel Substituted Triazinoindole Inhibitors of Aldose Reductase and Epalrestat ...   Elmazoglu, Zubeyir; Prnova, Marta Soltesova; Stefek, Milan; Ceylan, Asli F; Aschner, Michael; R ... R01ES010563 Neurotox Res (2021 Jun) 33713301 Exiting the NIEHS site 2021 
Protective Effects of Sodium Para-aminosalicylic Acid on Manganese-Induced Damage in Rat Pancreas.   Zhu, Xiaojuan; Xie, Bingyan; Liang, Dianyin; Qin, Wenxia; Zhao, Lin; Deng, Yue; Wen, Pingjing ... R01ES007331, R01ES010563 Biol Trace Elem Res (2021 Oct) 33405079 Exiting the NIEHS site 2021 
Review of the mechanism underlying mefloquine-induced neurotoxicity.   Martins, Airton C; Paoliello, Monica M B; Docea, Anca O; Santamaria, Abel; Tinkov, Alexey A; Sk ... R01ES007331, R01ES010563 Crit Rev Toxicol (2021 03) 33905310 Exiting the NIEHS site 2021 
S-allylcysteine induces cytotoxic effects in two human lung cancer cell lines via induction of oxida ...   Orozco-Morales, Mario; Hernández-Pedro, Norma Yanet; Barrios-Bernal, Pedro; Arrieta, Oscar; Ruiz ... R01ES010563 Anticancer Drugs (2021 Feb 01) 33136700 Exiting the NIEHS site 2021 
Sirtuins as molecular targets, mediators, and protective agents in metal-induced toxicity.   Tinkov, Alexey A; Nguyen, Thuy T; Santamaria, Abel; Bowman, Aaron B; Buha Djordjevic, Aleksandr ... R01ES007331, R01ES010563 Arch Toxicol (2021 07) 34028595 Exiting the NIEHS site 2021 
Social injustice in environmental health: A call for fortitude.   Aschner, Michael; Paoliello, Monica M B; Tsatsakis, Aristides; Bowman, Aaron B; Dorea, Jose G; ... R01ES007331, R01ES010563 Environ Res (2021 03) 33373610 Exiting the NIEHS site 2021 
Sodium P-aminosalicylic Acid Inhibits Manganese-Induced Neuroinflammation in BV2 Microglial Cells vi ...   Fang, Yuanyuan; Peng, Dongjie; Liang, Yuan; Lu, Lili; Li, Junyan; Zhao, Lin; Ou, Shiyan; Li, ... R01ES010563 Biol Trace Elem Res (2021 Sep) 33156491 Exiting the NIEHS site 2021 
The Effect of Lead Exposure on Autism Development.   Goel, Aanya; Aschner, Michael R01ES007331, R01ES010563 Int J Mol Sci (2021 Feb 06) 33561959 Exiting the NIEHS site 2021 
The Endocannabinoid System in Caenorhabditis elegans.   Estrada-Valencia, Rubén; de Lima, María Eduarda; Colonnello, Aline; Rangel-López, Edgar; Saraiva ... R01ES007331, R01ES010563 Rev Physiol Biochem Pharmacol (2021 Aug 17) 34401955 Exiting the NIEHS site 2021 
The Impact of Environmental Factors on Monogenic Mendelian Diseases.   Tukker, Anke M; Royal, Charmaine D; Bowman, Aaron B; McAllister, Kimberly A R01ES010563 Toxicol Sci (2021 Apr 27) 33677604 Exiting the NIEHS site 2021 
Therapeutic potential of alkaloids in autoimmune diseases: Promising candidates for clinical trials.   Khan, Haroon; Ullah, Hammad; Khattak, Sumaira; Aschner, Michael; Aguilar, Cristobal N; Halimi, ... R01ES007331, R01ES010563 Phytother Res (2021 Jan) 32667693 Exiting the NIEHS site 2021 
Therapeutic potential of marine peptides in glioblastoma: Mechanistic insights.   Ahmed, Salman; Hasan, Muhammad Mohtasheemul; Aschner, Michael; Mirzaei, Hamed; Alam, Waqas; Muk ... R01ES010563 Cell Signal (2021 11) 34487816 Exiting the NIEHS site 2021 
Whole body potassium as a biomarker for potassium uptake using a mouse model.   Tabbassum, Sana; Cheng, Pinjing; Yanko, Frank M; Balachandran, Rekha; Aschner, Michael; Bowman, ... R01ES007331, R01ES010563 Sci Rep (2021 03 18) 33737537 Exiting the NIEHS site 2021 
Zinc.   Skalny, Anatoly V; Aschner, Michael; Tinkov, Alexey A R01ES007331, R01ES010563 Adv Food Nutr Res (2021) 34112355 Exiting the NIEHS site 2021 
A Small-Molecule Modulator of Metal Homeostasis in Gram-Positive Pathogens.   Juttukonda, Lillian J; Beavers, William N; Unsihuay, Daisy; Kim, Kwangho; Pishchany, Gleb; Horn ... R01ES010563, T32ES007028 mBio (2020 10 27) 33109764 Exiting the NIEHS site 2020 
Are we rushing too much?   Aschner, Michael R01ES007331, R01ES010563 Food Chem Toxicol (2020 Sep) 32640328 Exiting the NIEHS site 2020 
Astrocyte-specific deletion of the transcription factor Yin Yang 1 in murine substantia nigra mitiga ...   Pajarillo, Edward; Johnson Jr, James; Rizor, Asha; Nyarko-Danquah, Ivan; Adinew, Getinet; Bornh ... R01ES007331, R01ES010563, R01ES031282 J Biol Chem (2020 Nov 13) 32893191 Exiting the NIEHS site 2020 
Brain manganese and the balance between essential roles and neurotoxicity.   Balachandran, Rekha C; Mukhopadhyay, Somshuvra; McBride, Danielle; Veevers, Jennifer; Harrison, ... P30ES026529, R01ES010563, R01ES024812, R01ES031401 J Biol Chem (2020 May 08) 32188696 Exiting the NIEHS site 2020 
Caloric restriction attenuates C57BL/6 J mouse lung injury and extra-pulmonary toxicity induced by r ...   Li, Daochuan; Chen, Shen; Li, Qiong; Chen, Liping; Zhang, Haiyan; Li, Huiyao; Yu, Dianke; Zha ... R01ES007331, R01ES010563 Part Fibre Toxicol (2020 06 05) 32503629 Exiting the NIEHS site 2020 
Cannabinoid-profiled agents improve cell survival via reduction of oxidative stress and inflammation ...   Elmazoglu, Zubeyir; Rangel-López, Edgar; Medina-Campos, Omar Noel; Pedraza-Chaverri, José; Túnez ... R01ES007331, R01ES010563 Neurochem Int (2020 Nov) 32781098 Exiting the NIEHS site 2020 
Cephalic Neuronal Vesicle Formation is Developmentally Dependent and Modified by Methylmercury and s ...   Ke, Tao; Santamaria, Abel; Rocha, Joao B T; Tinkov, Alex; Bornhorst, Julia; Bowman, Aaron B; A ... R01ES007331, R01ES010563 Neurochem Res (2020 Dec) 33037975 Exiting the NIEHS site 2020 
Chronic exposure to methylmercury induces puncta formation in cephalic dopaminergic neurons in Caeno ...   Ke, Tao; Tsatsakis, Aristidis; Santamaría, Abel; Antunes Soare, Félix Alexandre; Tinkov, Alexey ... R01ES007331, R01ES010563 Neurotoxicology (2020 03) 31935438 Exiting the NIEHS site 2020 
Comparing the Neuroprotective Effects of Caffeic Acid in Rat Cortical Slices and Caenorhabditis eleg ...   Colonnello, Aline; Aguilera-Portillo, Gabriela; Rubio-López, Leonardo C; Robles-Bañuelos, Benjam ... R01ES007331, R01ES010563 Neurotox Res (2020 Feb) 31773641 Exiting the NIEHS site 2020 
Differential susceptibility of PC12 and BRL cells and the regulatory role of HIF-1α signaling pathwa ...   Liu, Tingting; Gao, Qianqian; Yang, Bobo; Yin, Changsheng; Chang, Jie; Qian, Hai; Xing, Guang ... R01ES007331, R01ES010563 Toxicol Lett (2020 Oct 01) 32461003 Exiting the NIEHS site 2020 
Disparity in Risk Factor Severity for Early Childhood Blood Lead among Predominantly African-America ...   Yeter, Deniz; Banks, Ellen C; Aschner, Michael R01ES007331, R01ES010563 Int J Environ Res Public Health (2020 02 28) 32121216 Exiting the NIEHS site 2020 
Drp-1-Dependent Mitochondrial Fragmentation Contributes to Cobalt Chloride-Induced Toxicity in Caeno ...   Zheng, Fuli; Chen, Pan; Li, Huangyuan; Aschner, Michael R01ES010563 Toxicol Sci (2020 09 01) 32617571 Exiting the NIEHS site 2020 
Dysregulation of TFEB contributes to manganese-induced autophagic failure and mitochondrial dysfunct ...   Zhang, Ziyan; Yan, Jingqi; Bowman, Aaron B; Bryan, Miles R; Singh, Rajat; Aschner, Michael R01ES007331, R01ES010563 Autophagy (2020 08) 31690173 Exiting the NIEHS site 2020 
Environmental influence on neurodevelopmental disorders: Potential association of heavy metal exposu ...   Ijomone, Omamuyovwi M; Olung, Nzube F; Akingbade, Grace T; Okoh, Comfort O A; Aschner, Michael R01ES007331, R01ES010563 J Trace Elem Med Biol (2020 Dec) 32891009 Exiting the NIEHS site 2020 
Epigenetic influence of environmentally neurotoxic metals.   Ijomone, Omamuyovwi M; Ijomone, Olayemi K; Iroegbu, Joy D; Ifenatuoha, Chibuzor W; Olung, Nzube ... R01ES007331, R01ES010563 Neurotoxicology (2020 Dec) 32882300 Exiting the NIEHS site 2020 
Generating Bacterial Foods in Toxicology Studies with Caenorhabditis elegans.   Ke, Tao; Santamaría, Abel; Tinkov, Alexey A; Bornhorst, Julia; Aschner, Michael R01ES007331, R01ES010563 Curr Protoc Toxicol (2020 06) 32436649 Exiting the NIEHS site 2020 
High throughput fluorimetric assessment of iron traffic and chelation in iron-overloaded Caenorhabdi ...   Espósito, Breno Pannia; Martins, Airton Cunha; de Carvalho, Rodrigo Rodrigues Victor; Aschner, M ... R01ES007331, R01ES010563 Biometals (2020 10) 32979113 Exiting the NIEHS site 2020 
Huntington's disease genotype suppresses global manganese-responsive processes in pre-manifest and m ...   Pfalzer, Anna C; Wilcox, Jordyn M; Codreanu, Simona G; Totten, Melissa; Bichell, Terry J V; Hal ... R01ES010563, T32ES007028 Metallomics (2020 Jul 22) 32421118 Exiting the NIEHS site 2020 
Identification of a selective manganese ionophore that enables nonlethal quantification of cellular ...   Horning, Kyle J; Joshi, Piyush; Nitin, Rachana; Balachandran, Rekha C; Yanko, Frank M; Kim, Kw ... R01ES010563, T32ES007028 J Biol Chem (2020 Mar 20) 32047113 Exiting the NIEHS site 2020 
Maintaining Translational Relevance in Animal Models of Manganese Neurotoxicity.   Taylor, Cherish A; Tuschl, Karin; Nicolai, Merle M; Bornhorst, Julia; Gubert, Priscila; Varão, ... R01ES007331, R01ES010563, R01ES024812 J Nutr (2020 Jun 01) 32211802 Exiting the NIEHS site 2020 
Manganese Accumulation in the Brain via Various Transporters and Its Neurotoxicity Mechanisms.   Nyarko-Danquah, Ivan; Pajarillo, Edward; Digman, Alexis; Soliman, Karam F A; Aschner, Michael; ... R01ES007331, R01ES010563, R01ES031282 Molecules (2020 Dec 12) 33322668 Exiting the NIEHS site 2020 
Manganese Acts upon Insulin/IGF Receptors to Phosphorylate AKT and Increase Glucose Uptake in Huntin ...   Bryan, Miles R; Nordham, Kristen D; Rose, Daniel I R; O'Brien, Michael T; Joshi, Piyush; Foshag ... R01ES010563, T32ES007028 Mol Neurobiol (2020 Mar) 31797328 Exiting the NIEHS site 2020 
Manganese-induced Mitochondrial Dysfunction Is Not Detectable at Exposures Below the Acute Cytotoxic ...   Warren, Emily B; Bryan, Miles R; Morcillo, Patricia; Hardeman, Keisha N; Aschner, Michael; Bowm ... R01ES010563 Toxicol Sci (2020 Aug 01) 32492146 Exiting the NIEHS site 2020 
Manganese-induced neurodegenerative diseases and possible therapeutic approaches.   Martins Jr, Airton C; Gubert, Priscila; Villas Boas, Gustavo R; Meirelles Paes, Marina; Santamar ... R01ES007331, R01ES010563 Expert Rev Neurother (2020 11) 32799578 Exiting the NIEHS site 2020 
Metal environmental contamination within different human exposure context- specific and non-specific ...   de Andrade, Vanda Lopes; Cota, Madalena; Serrazina, Daniela; Mateus, Maria Luisa; Aschner, Mich ... R01ES007331, R01ES010563 Toxicol Lett (2020 May 15) 31935480 Exiting the NIEHS site 2020 
Metal-induced neurotoxicity in a RAGE-expressing C. elegans model.   Lawes, Michael; Pinkas, Adi; Frohlich, Bailey A; Iroegbu, Joy D; Ijomone, Omamuyovwi M; Aschner ... R01ES007331, R01ES010563 Neurotoxicology (2020 09) 32621835 Exiting the NIEHS site 2020 
Neurotoxicity of e-cigarettes.   Ruszkiewicz, Joanna A; Zhang, Ziyan; Gonçalves, Filipe Marques; Tizabi, Yousef; Zelikoff, Judit ... R01ES007331, R01ES010563 Food Chem Toxicol (2020 Apr) 32145355 Exiting the NIEHS site 2020 
Nicotine and the nicotinic cholinergic system in COVID-19.   Tizabi, Yousef; Getachew, Bruk; Copeland, Robert L; Aschner, Michael R01ES007331, R01ES010563 FEBS J (2020 09) 32790936 Exiting the NIEHS site 2020 
Oleamide Induces Cell Death in Glioblastoma RG2 Cells by a Cannabinoid Receptor-Independent Mechanis ...   Torres-Román, Ana Laura; García-Hernández, Victor Manuel; Rangel-López, Edgar; Ruiz-García, Erik ... R01ES010563 Neurotox Res (2020 Dec) 32930995 Exiting the NIEHS site 2020 
Redox toxicology of environmental chemicals causing oxidative stress.   Zheng, Fuli; Gonçalves, Filipe Marques; Abiko, Yumi; Li, Huangyuan; Kumagai, Yoshito; Aschner, ... R01ES007331, R01ES010563 Redox Biol (2020 Jul) 32336668 Exiting the NIEHS site 2020 
S-Allylcysteine Protects Against Excitotoxic Damage in Rat Cortical Slices Via Reduction of Oxidativ ...   Reyes-Soto, Carolina Y; Rangel-López, Edgar; Galván-Arzate, Sonia; Colín-González, Ana Laura; Si ... R01ES010563 Neurotox Res (2020 Dec) 32813208 Exiting the NIEHS site 2020 
Sulfhydryl groups as targets of mercury toxicity.   Ajsuvakova, Olga P; Tinkov, Alexey A; Aschner, Michael; Rocha, João B T; Michalke, Bernhard; Sk ... R01ES007331, R01ES010563 Coord Chem Rev (2020 Aug 15) 32905350 Exiting the NIEHS site 2020 
Thallium Toxicity in Caenorhabditis elegans: Involvement of the SKN-1 Pathway and Protection by S-Al ...   Hurtado-Díaz, María Ester; Estrada-Valencia, Rubén; Rangel-López, Edgar; Maya-López, Marisol; Co ... R01ES010563 Neurotox Res (2020 Aug) 32468422 Exiting the NIEHS site 2020 
The effects of manganese overexposure on brain health.   Miah, Mahfuzur R; Ijomone, Omamuyovwi M; Okoh, Comfort O A; Ijomone, Olayemi K; Akingbade, Grac ... R01ES007331, R01ES010563 Neurochem Int (2020 May) 31972215 Exiting the NIEHS site 2020 
The impact of manganese on neurotransmitter systems.   Soares, Ana Thalita Gonçalves; Silva, Aline de Castro; Tinkov, Alexey A; Khan, Haroon; Santamarí ... R01ES007331, R01ES010563 J Trace Elem Med Biol (2020 May 20) 32480053 Exiting the NIEHS site 2020 
The Role of Human LRRK2 in Methylmercury-Induced Inhibition of Microvesicle Formation of Cephalic Ne ...   Ke, Tao; Santamaria, Abel; Rocha, Joao B T; Tinkov, Alexey A; Lu, Rongzhu; Bowman, Aaron B; As ... R01ES007331, R01ES010563 Neurotox Res (2020 Oct) 32725544 Exiting the NIEHS site 2020 
The role of poly(ADP-ribose) polymerases in manganese exposed Caenorhabditis elegans.   Neumann, Catherine; Baesler, Jessica; Steffen, Gereon; Nicolai, Merle Marie; Zubel, Tabea; Asch ... R01ES007331, R01ES010563 J Trace Elem Med Biol (2020 Jan) 31546209 Exiting the NIEHS site 2020 
The transcription factor REST up-regulates tyrosine hydroxylase and antiapoptotic genes and protects ...   Pajarillo, Edward; Rizor, Asha; Son, Deok-Soo; Aschner, Michael; Lee, Eunsook R01ES007331, R01ES010563, R01ES031282 J Biol Chem (2020 Mar 06) 32001620 Exiting the NIEHS site 2020 
Toxic metal exposure as a possible risk factor for COVID-19 and other respiratory infectious disease ...   Skalny, Anatoly V; Lima, Thania Rios Rossi; Ke, Tao; Zhou, Ji-Chang; Bornhorst, Julia; Alekseen ... R01ES007331, R01ES010563 Food Chem Toxicol (2020 Dec) 33069759 Exiting the NIEHS site 2020 
Transcriptomic and Proteomic Tools in the Study of Hg Toxicity: What Is Missing?   Oliveira, Cláudia S; Segatto, Ana L A; Nogara, Pablo A; Piccoli, Bruna C; Loreto, Élgion L S; A ... R01ES007331, R01ES010563 Front Genet (2020) 32431728 Exiting the NIEHS site 2020 
A review of the alleged health hazards of monosodium glutamate.   Zanfirescu, Anca; Ungurianu, Anca; Tsatsakis, Aristides M; Nițulescu, George M; Kouretas, Demet ... R01ES007331, R01ES010563 Compr Rev Food Sci Food Saf (2019 Jul) 31920467 Exiting the NIEHS site 2019 
Acute manganese treatment restores defective autophagic cargo loading in Huntington's disease cell l ...   Bryan, Miles R; O'Brien, Michael T; Nordham, Kristen D; Rose, Daniel I R; Foshage, Audra M; Jos ... R01ES010563, T32ES007028 Hum Mol Genet (2019 11 15) 31600787 Exiting the NIEHS site 2019 
Bacteria affect Caenorhabditis elegans responses to MeHg toxicity.   Ke, Tao; Aschner, Michael R01ES007331, R01ES010563 Neurotoxicology (2019 12) 31542475 Exiting the NIEHS site 2019 
Brain diseases in changing climate.   Ruszkiewicz, Joanna A; Tinkov, Alexey A; Skalny, Anatoly V; Siokas, Vasileios; Dardiotis, Efthi ... R01ES007331, R01ES010563 Environ Res (2019 10) 31416010 Exiting the NIEHS site 2019 
Caenorhabditis elegans and its applicability to studies on restless legs syndrome.   Chen, Pan; Ijomone, Omamuyovwi Meashack; Lee, Kun He; Aschner, Michael R01ES007331, R01ES010563 Adv Pharmacol (2019) 31229169 Exiting the NIEHS site 2019 
Caenorhabditis elegans as a tool for environmental risk assessment: emerging and promising applicati ...   Queirós, L; Pereira, J L; Gonçalves, F J M; Pacheco, M; Aschner, M; Pereira, P R01ES007331, R01ES010563 Crit Rev Toxicol (2019 May) 31268799 Exiting the NIEHS site 2019 
Colonic Injuries Induced by Inhalational Exposure to Particulate-Matter Air Pollution.   Li, Xiaobo; Cui, Jian; Yang, Hongbao; Sun, Hao; Lu, Runze; Gao, Na; Meng, Qingtao; Wu, Shens ... R01ES007331, R01ES010563 Adv Sci (Weinh) (2019 Jun 05) 31179224 Exiting the NIEHS site 2019 
Combined exposure to methylmercury and manganese during L1 larval stage causes motor dysfunction, ch ...   Schetinger, Maria Rosa Chitolina; Peres, Tanara V; Arantes, Letícia P; Carvalho, Fabiano; Dressl ... R01ES007331, R01ES010563 Toxicology (2019 01 01) 30336192 Exiting the NIEHS site 2019 
Editorial: Sex and Gene-Dependent Neurotoxicity.   Ruszkiewicz, Joanna A; Aschner, Michael R01ES007331, R01ES010563 Front Genet (2019) 30891065 Exiting the NIEHS site 2019 
Endothelial cells are critical regulators of iron transport in a model of the human blood-brain barr ...   Chiou, Brian; Neal, Emma H; Bowman, Aaron B; Lippmann, Ethan S; Simpson, Ian A; Connor, James ... R01ES010563 J Cereb Blood Flow Metab (2019 11) 29911470 Exiting the NIEHS site 2019 
Glutathione antioxidant system and methylmercury-induced neurotoxicity: An intriguing interplay.   Farina, Marcelo; Aschner, Michael R01ES007331, R01ES010563 Biochim Biophys Acta Gen Subj (2019 12) 30659883 Exiting the NIEHS site 2019 
Human-induced pluripotent stems cells as a model to dissect the selective neurotoxicity of methylmer ...   Prince, Lisa M; Aschner, Michael; Bowman, Aaron B R01ES007331, R01ES010563 Biochim Biophys Acta Gen Subj (2019 12) 30742955 Exiting the NIEHS site 2019 
Huntington's disease associated resistance to Mn neurotoxicity is neurodevelopmental stage and neuro ...   Joshi, Piyush; Bodnya, Caroline; Ilieva, Ilyana; Neely, M Diana; Aschner, Michael; Bowman, Aar ... R01ES010563 Neurotoxicology (2019 12) 31545971 Exiting the NIEHS site 2019 
Iron and manganese-related CNS toxicity: mechanisms, diagnosis and treatment.   Chen, Pan; Totten, Melissa; Zhang, Ziyan; Bucinca, Hana; Erikson, Keith; Santamaría, Abel; Bow ... R01ES007331, R01ES010563 Expert Rev Neurother (2019 Mar) 30759034 Exiting the NIEHS site 2019 
LRRK2 kinase plays a critical role in manganese-induced inflammation and apoptosis in microglia.   Kim, Judong; Pajarillo, Edward; Rizor, Asha; Son, Deok-Soo; Lee, Jayden; Aschner, Michael; Lee ... R01ES010563, R01ES031282 PLoS One (2019) 30645642 Exiting the NIEHS site 2019 
MALAT1 rs664589 Polymorphism Inhibits Binding to miR-194-5p, Contributing to Colorectal Cancer Risk, ...   Wu, Shenshen; Sun, Hao; Wang, Yajie; Yang, Xi; Meng, Qingtao; Yang, Hongbao; Zhu, Haitao; Tan ... R01ES007331, R01ES010563 Cancer Res (2019 10 15) 31311811 Exiting the NIEHS site 2019 
Manganese: Its Role in Disease and Health.   Erikson, Keith M; Aschner, Michael R01ES007331, R01ES010563 Met Ions Life Sci (2019 Jan 14) 30855111 Exiting the NIEHS site 2019 
Methylmercury Epigenetics.   Culbreth, Megan; Aschner, Michael R01ES007331, R01ES010563, T32ES007026 Toxics (2019 Nov 09) 31717489 Exiting the NIEHS site 2019 
Natural Products in the Promotion of Healthspan and Longevity.   Niso-Santano, Mireia; González-Polo, Rosa A; Paredes-Barquero, Marta; Fuentes, José M; Aschner, ... R01ES007331, R01ES010563 Clin Pharmacol Transl Med (2019) 31363716 Exiting the NIEHS site 2019 
New Insights on the Role of Manganese in Alzheimer's Disease and Parkinson's Disease.   Martins Jr, Airton Cunha; Morcillo, Patricia; Ijomone, Omamuyovwi Meashack; Venkataramani, Vivek ... R01ES007331, R01ES010563 Int J Environ Res Public Health (2019 Sep 22) 31546716 Exiting the NIEHS site 2019 
Organotins in obesity and associated metabolic disturbances.   Tinkov, Alexey A; Ajsuvakova, Olga P; Skalnaya, Margarita G; Skalny, Anatoly V; Aschner, Michae ... R01ES007331, R01ES010563 J Inorg Biochem (2019 02) 30458368 Exiting the NIEHS site 2019 
Overview of the effects of chemical mixtures with endocrine disrupting activity in the context of re ...   Margina, Denisa; Nițulescu, George Mihai; Ungurianu, Anca; Mesnage, Robin; Goumenou, Marina; Sa ... R01ES007331, R01ES010563 World Acad Sci J (2019 Jul) 32346674 Exiting the NIEHS site 2019 
Polyphenols in the treatment of autoimmune diseases.   Khan, Haroon; Sureda, Antoni; Belwal, Tarun; Çetinkaya, Sümeyra; Süntar, İpek; Tejada, Silvia; ... R01ES007331, R01ES010563 Autoimmun Rev (2019 Jul) 31059841 Exiting the NIEHS site 2019 
Post-translational modifications in MeHg-induced neurotoxicity.   Ke, Tao; Gonçalves, Filipe Marques; Gonçalves, Cinara Ludvig; Dos Santos, Alessandra Antunes; Ro ... R01ES007331, R01ES010563 Biochim Biophys Acta Mol Basis Dis (2019 08 01) 30385410 Exiting the NIEHS site 2019 
Role of Astrocytes in Manganese Neurotoxicity Revisited.   Ke, Tao; Sidoryk-Wegrzynowicz, Marta; Pajarillo, Edward; Rizor, Asha; Soares, Félix Alexandre A ... R01ES007331, R01ES010563, R01ES031282 Neurochem Res (2019 Nov) 31571097 Exiting the NIEHS site 2019 
Sex-Specific Differences in Redox Homeostasis in Brain Norm and Disease.   Ruszkiewicz, Joanna A; Miranda-Vizuete, Antonio; Tinkov, Alexey A; Skalnaya, Margarita G; Skalny ... R01ES007331, R01ES010563 J Mol Neurosci (2019 Feb) 30604380 Exiting the NIEHS site 2019 
Sex-Specific Response of Caenorhabditis elegans to Methylmercury Toxicity.   Ruszkiewicz, Joanna A; Teixeira de Macedo, Gabriel; Miranda-Vizuete, Antonio; Bowman, Aaron B; B ... R01ES007331, R01ES010563 Neurotox Res (2019 Jan) 30155682 Exiting the NIEHS site 2019 
Small Molecule Modifiers of In Vitro Manganese Transport Alter Toxicity In Vivo.   Peres, Tanara V; Horning, Kyle J; Bornhorst, Julia; Schwerdtle, Tanja; Bowman, Aaron B; Aschner ... R01ES007331, R01ES010563 Biol Trace Elem Res (2019 Mar) 30267310 Exiting the NIEHS site 2019 
The role of astrocytic glutamate transporters GLT-1 and GLAST in neurological disorders: Potential t ...   Pajarillo, Edward; Rizor, Asha; Lee, Jayden; Aschner, Michael; Lee, Eunsook R01ES007331, R01ES010563, R01ES031282 Neuropharmacology (2019 Dec 15) 30851309 Exiting the NIEHS site 2019 
The role of posttranslational modifications of α-synuclein and LRRK2 in Parkinson's disease: Potenti ...   Pajarillo, Edward; Rizor, Asha; Lee, Jayden; Aschner, Michael; Lee, Eunsook R01ES007331, R01ES010563, R01ES031282 Biochim Biophys Acta Mol Basis Dis (2019 Aug 01) 30481588 Exiting the NIEHS site 2019 
Treatment of Caenorhabditis elegans with Small Selenium Species Enhances Antioxidant Defense Systems ...   Rohn, Isabelle; Raschke, Stefanie; Aschner, Michael; Tuck, Simon; Kuehnelt, Doris; Kipp, Anna; ... R01ES007331, R01ES010563 Mol Nutr Food Res (2019 May) 30815971 Exiting the NIEHS site 2019 
Triclosan induces PC12 cells injury is accompanied by inhibition of AKT/mTOR and activation of p38 p ...   Li, Shao-Jun; Chen, Pan; Peres, Tanara Vieira; Villahoz, Beatriz Ferrer; Zhang, Ziyan; Miah, M ... R01ES007331, R01ES010563 Neurotoxicology (2019 09) 31381933 Exiting the NIEHS site 2019 
Zn homeostasis in genetic models of Parkinson's disease in Caenorhabditis elegans.   Baesler, Jessica; Kopp, Johannes F; Pohl, Gabriele; Aschner, Michael; Haase, Hajo; Schwerdtle, ... R01ES007331, R01ES010563 J Trace Elem Med Biol (2019 Sep) 31345364 Exiting the NIEHS site 2019 
17β-estradiol and tamoxifen protect mice from manganese-induced dopaminergic neurotoxicity.   Pajarillo, Edward; Johnson Jr, James; Kim, Judong; Karki, Pratap; Son, Deok-Soo; Aschner, Mich ... R01ES010563 Neurotoxicology (2018 03) 29183790 Exiting the NIEHS site 2018 
Arundic Acid Increases Expression and Function of Astrocytic Glutamate Transporter EAAT1 Via the ERK ...   Karki, Pratap; Hong, Peter; Johnson Jr, James; Pajarillo, Edward; Son, Deok-Soo; Aschner, Mich ... R01ES010563, R01ES031282 Mol Neurobiol (2018 Jun) 28812276 Exiting the NIEHS site 2018 
Assessment of occupational exposures to multiple metals with urinary porphyrin profiles.   de Andrade, V Lopes; Mateus, M L; Aschner, M; Dos Santos, Ap Marreilha R01ES007331, R01ES010563 J Integr OMICS (2018 Jun) 30666282 Exiting the NIEHS site 2018 
Association of exposure to manganese and iron with striatal and thalamic GABA and other neurometabol ...   Casjens, Swaantje; Dydak, Urike; Dharmadhikari, Shalmali; Lotz, Anne; Lehnert, Martin; Quetsche ... R01ES010563 Neurotoxicology (2018 Jan) 28803850 Exiting the NIEHS site 2018 
Biomarkers of exposure and effect in a working population exposed to lead, manganese and arsenic.   Serrazina, Daniela C; Lopes De Andrade, Vanda; Cota, Madalena; Mateus, Maria Luísa; Aschner, Mi ... R01ES007331, R01ES010563 J Toxicol Environ Health A (2018) 30296394 Exiting the NIEHS site 2018 
C. elegans as a model in developmental neurotoxicology.   Ruszkiewicz, Joanna A; Pinkas, Adi; Miah, Mahfuzur R; Weitz, Rebecca L; Lawes, Michael J A; Aki ... R01ES007331, R01ES010563 Toxicol Appl Pharmacol (2018 09 01) 29550512 Exiting the NIEHS site 2018 
C. elegans-An Emerging Model to Study Metal-Induced RAGE-Related Pathologies.   Pinkas, Adi; Cunha Martins Jr, Airton; Aschner, Michael R01ES007331, R01ES010563 Int J Environ Res Public Health (2018 Jul 04) 29973513 Exiting the NIEHS site 2018 
DR4 mediates the progression, invasion, metastasis and survival of colorectal cancer through the Sp1 ...   Wu, Shenshen; Meng, Qingtao; Zhang, Chengcheng; Sun, Hao; Lu, Runze; Gao, Na; Yang, Hongbao; ... R01ES007331, R01ES010563 Int J Cancer (2018 Jul 15) 29446085 Exiting the NIEHS site 2018 
Molecular Pathways Associated With Methylmercury-Induced Nrf2 Modulation.   Unoki, Takamitsu; Akiyama, Masahiro; Kumagai, Yoshito; Gonçalves, Filipe Marques; Farina, Marce ... R01ES007331, R01ES010563 Front Genet (2018) 30271424 Exiting the NIEHS site 2018 
MPO Promoter Polymorphism rs2333227 Enhances Malignant Phenotypes of Colorectal Cancer by Altering t ...   Meng, Qingtao; Wu, Shenshen; Wang, Yajie; Xu, Jin; Sun, Hao; Lu, Runze; Gao, Na; Yang, Hongb ... R01ES007331, R01ES010563 Cancer Res (2018 May 15) 29540402 Exiting the NIEHS site 2018 
Neurodevelopmental Effects of Mercury.   Oliveira, Cláudia S; Nogara, Pablo A; Ardisson-Araújo, Daniel M P; Aschner, Michael; Rocha, Joã ... R01ES007331, R01ES010563 Adv Neurotoxicol (2018) 32346667 Exiting the NIEHS site 2018 
Pharmaceutical iron formulations do not cross a model of the human blood-brain barrier.   Chiou, Brian; Neal, Emma H; Bowman, Aaron B; Lippmann, Ethan S; Simpson, Ian A; Connor, James ... R01ES010563 PLoS One (2018) 29889872 Exiting the NIEHS site 2018 
Phosphatidylinositol 3 kinase (PI3K) modulates manganese homeostasis and manganese-induced cell sign ...   Bryan, Miles R; Uhouse, Michael A; Nordham, Kristen D; Joshi, Piyush; Rose, Daniel I R; O'Brien ... R01ES010563 Neurotoxicology (2018 Jan) 28780388 Exiting the NIEHS site 2018 
Quinolinic acid and glutamatergic neurodegeneration in Caenorhabditis elegans.   da Silveira, Tássia Limana; Zamberlan, Daniele Coradine; Arantes, Leticia Priscilla; Machado, Ma ... R01ES007331, R01ES010563 Neurotoxicology (2018 07) 29702159 Exiting the NIEHS site 2018 
Role of Caenorhabditis elegans AKT-1/2 and SGK-1 in Manganese Toxicity.   Peres, Tanara V; Arantes, Leticia P; Miah, Mahfuzur R; Bornhorst, Julia; Schwerdtle, Tanja; Bow ... R01ES007331, R01ES010563 Neurotox Res (2018 Oct) 29882004 Exiting the NIEHS site 2018 
Selenium species-dependent toxicity, bioavailability and metabolic transformations in Caenorhabditis ...   Rohn, Isabelle; Marschall, Talke Anu; Kroepfl, Nina; Jensen, Kenneth Bendix; Aschner, Michael; ... R01ES007331, R01ES010563 Metallomics (2018 06 20) 29770420 Exiting the NIEHS site 2018 
System-specific neurodegeneration following glucotoxicity in the C. elegans model.   Pinkas, Adi; Lawes, Michael; Aschner, Michael R01ES007331, R01ES010563 Neurotoxicology (2018 09) 30036563 Exiting the NIEHS site 2018 
Valproate and sodium butyrate attenuate manganese-decreased locomotor activity and astrocytic glutam ...   Johnson Jr, James; Pajarillo, Edward Alain B; Taka, Equar; Reams, Romonia; Son, Deok-Soo; Aschn ... R01ES010563 Neurotoxicology (2018 Jan) 28610743 Exiting the NIEHS site 2018 
Valproic acid attenuates manganese-induced reduction in expression of GLT-1 and GLAST with concomita ...   Johnson Jr, James; Pajarillo, Edward; Karki, Pratap; Kim, Judong; Son, Deok-Soo; Aschner, Mich ... R01ES010563, R01ES031282 Neurotoxicology (2018 Jul) 29778792 Exiting the NIEHS site 2018 
Accelerated differentiation of human induced pluripotent stem cells to blood-brain barrier endotheli ...   Hollmann, Emma K; Bailey, Amanda K; Potharazu, Archit V; Neely, M Diana; Bowman, Aaron B; Lippm ... R01ES010563 Fluids Barriers CNS (2017 Apr 13) 28407791 Exiting the NIEHS site 2017 
AGEs/RAGE-Related Neurodegeneration: daf-16 as a Mediator, Insulin as an Ameliorant, and C. elegans ...   Pinkas, Adi; Aschner, Michael R01ES007331, R01ES010563 Chem Res Toxicol (2017 Jan 17) 27704837 Exiting the NIEHS site 2017 
Associations between former exposure to manganese and olfaction in an elderly population: Results fr ...   Casjens, Swaantje; Pesch, Beate; Robens, Sibylle; Kendzia, Benjamin; Behrens, Thomas; Weiss, T ... R01ES010563 Neurotoxicology (2017 Jan) 27865828 Exiting the NIEHS site 2017 
Biomarkers of mercury toxicity: Past, present, and future trends.   Branco, Vasco; Caito, Sam; Farina, Marcelo; Teixeira da Rocha, João; Aschner, Michael; Carvalho ... R01ES007331, R01ES010563 J Toxicol Environ Health B Crit Rev (2017) 28379072 Exiting the NIEHS site 2017 
BXD recombinant inbred strains participate in social preference, anxiety and depression behaviors al ...   López-Granero, Caridad; Antunes Dos Santos, Alessandra; Ferrer, Beatriz; Culbreth, Megan; Chakra ... R01ES007331, R01ES010563 Psychoneuroendocrinology (2017 Jun) 28324704 Exiting the NIEHS site 2017 
Defective Sphingosine-1-phosphate metabolism is a druggable target in Huntington's disease.   Di Pardo, Alba; Amico, Enrico; Basit, Abdul; Armirotti, Andrea; Joshi, Piyush; Neely, M Diana; ... R01ES010563 Sci Rep (2017 07 13) 28706199 Exiting the NIEHS site 2017 
Disease-Toxicant Interactions in Parkinson's Disease Neuropathology.   Kwakye, Gunnar F; McMinimy, Rachael A; Aschner, Michael R01ES007331, R01ES010563 Neurochem Res (2017 Jun) 27613618 Exiting the NIEHS site 2017 
From the Cover: Manganese and Rotenone-Induced Oxidative Stress Signatures Differ in iPSC-Derived Hu ...   Neely, M Diana; Davison, Carrie Ann; Aschner, Michael; Bowman, Aaron B R01ES010563 Toxicol Sci (2017 Oct 01) 28962525 Exiting the NIEHS site 2017 
Frontiers in Toxicogenomics in the Twenty-First Century-the Grand Challenge: To Understand How the G ...   Ruden, Douglas M; Gurdziel, Katherine; Aschner, Michael P30ES020957, R01ES007331, R01ES010563 Front Genet (2017) 29170679 Exiting the NIEHS site 2017 
Manganese and the Insulin-IGF Signaling Network in Huntington's Disease and Other Neurodegenerative ...   Bryan, Miles R; Bowman, Aaron B R01ES010563 Adv Neurobiol (2017) 28889265 Exiting the NIEHS site 2017 
Manganese Control of Glutamate Transporters' Gene Expression.   Lee, Eunsook; Karki, Pratap; Johnson Jr, James; Hong, Peter; Aschner, Michael R01ES010563 Adv Neurobiol (2017) 28828603 Exiting the NIEHS site 2017 
Metals and Circadian Rhythms.   Parmalee, Nancy L; Aschner, Michael R01ES007331, R01ES010563 Adv Neurotoxicol (2017) 30729219 Exiting the NIEHS site 2017 
Neuroprotective and Therapeutic Strategies for Manganese-Induced Neurotoxicity.   Marreilha Dos Santos, A P; Andrade, V; Aschner, M R01ES007331, R01ES010563 Clin Pharmacol Transl Med (2017) 30854510 Exiting the NIEHS site 2017 
Neurotoxic effect of active ingredients in sunscreen products, a contemporary review.   Ruszkiewicz, Joanna A; Pinkas, Adi; Ferrer, Beatriz; Peres, Tanara V; Tsatsakis, Aristides; Asc ... R01ES007331, R01ES010563 Toxicol Rep (2017) 28959646 Exiting the NIEHS site 2017 
Neurotoxicity of fragrance compounds: A review.   Pinkas, Adi; Gonçalves, Cinara Ludvig; Aschner, Michael R01ES007331, R01ES010563 Environ Res (2017 Oct) 28683407 Exiting the NIEHS site 2017 
Occupational Exposure to Manganese and Fine Motor Skills in Elderly Men: Results from the Heinz Nixd ...   Pesch, Beate; Casjens, Swaantje; Weiss, Tobias; Kendzia, Benjamin; Arendt, Marina; Eisele, Lew ... R01ES010563 Ann Work Expo Health (2017 Nov 10) 29136419 Exiting the NIEHS site 2017 
Phenotypic Discordance in Siblings with Identical Compound Heterozygous PARK2 Mutations.   Isaacs, David; Claassen, Daniel; Bowman, Aaron B; Hedera, Peter R01ES010563 Brain Sci (2017 Jun 24) 28672806 Exiting the NIEHS site 2017 
Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse mo ...   Bichell, Terry Jo V; Wegrzynowicz, Michal; Tipps, K Grace; Bradley, Emma M; Uhouse, Michael A; ... R01ES010563, T32ES007028 Biochim Biophys Acta Mol Basis Dis (2017 06) 28213125 Exiting the NIEHS site 2017 
Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) poten ...   Aschner, Michael; Ceccatelli, Sandra; Daneshian, Mardas; Fritsche, Ellen; Hasiwa, Nina; Hartung ... R01ES007331, R01ES010563, R01ES014901 ALTEX (2017) 27452664 Exiting the NIEHS site 2017 
Relationships Between Essential Manganese Biology and Manganese Toxicity in Neurological Disease.   Pfalzer, Anna C; Bowman, Aaron B R01ES010563, T32ES007028 Curr Environ Health Rep (2017 Jun) 28417441 Exiting the NIEHS site 2017 
Role of matrix metalloproteinase-2/9 (MMP2/9) in lead-induced changes in an in vitro blood-brain bar ...   Liu, Xinqin; Su, Peng; Meng, Shanshan; Aschner, Michael; Cao, Yupeng; Luo, Wenjing; Zheng, Ga ... R01ES007331, R01ES010563 Int J Biol Sci (2017) 29209140 Exiting the NIEHS site 2017 
Suppression of PTPN6 exacerbates aluminum oxide nanoparticle-induced COPD-like lesions in mice throu ...   Li, Xiaobo; Yang, Hongbao; Wu, Shenshen; Meng, Qingtao; Sun, Hao; Lu, Runze; Cui, Jian; Zheng ... R01ES007331, R01ES010563 Part Fibre Toxicol (2017 Dec 12) 29233151 Exiting the NIEHS site 2017 
Taurine ameliorates particulate matter-induced emphysema by switching on mitochondrial NADH dehydrog ...   Li, Xiaobo; Yang, Hongbao; Sun, Hao; Lu, Runze; Zhang, Chengcheng; Gao, Na; Meng, Qingtao; Wu ... R01ES007331, R01ES010563 Proc Natl Acad Sci U S A (2017 Nov 07) 29078374 Exiting the NIEHS site 2017 
The catecholaminergic neurotransmitter system in methylmercury-induced neurotoxicity.   Farina, Marcelo; Aschner, Michael; da Rocha, João Batista Teixeira R01ES007331, R01ES010563 Adv Neurotoxicol (2017) 32346666 Exiting the NIEHS site 2017 
Toxic Mechanisms Underlying Motor Activity Changes Induced by a Mixture of Lead, Arsenic and Mangane ...   Andrade, Vanda; Mateus, M Luísa; Batoréu, M Camila; Aschner, Michael; Dos Santos, Ap Marreilha R01ES007331, R01ES010563 EC Pharmacol Toxicol (2017) 31633124 Exiting the NIEHS site 2017 
Toxicology of Lead and Its Damage to Mammalian Organs.   Caito, Samuel; Lopes, Ana Carolina B Almeida; Paoliello, Monica M B; Aschner, Michael R01ES007331, R01ES010563 Met Ions Life Sci (2017 Apr 10) 28731309 Exiting the NIEHS site 2017 
Transcriptional Regulation of Human Transforming Growth Factor-α in Astrocytes.   Karki, Pratap; Johnson Jr, James; Son, Deok-Soo; Aschner, Michael; Lee, Eunsook R01ES007331, R01ES010563 Mol Neurobiol (2017 03) 26797516 Exiting the NIEHS site 2017 
XRCC1 mediated the development of cervival cancer through a novel Sp1/Krox-20 swich.   Meng, Qingtao; Wang, Shizhi; Tang, Weiyan; Wu, Shenshen; Gao, Na; Zhang, Chengcheng; Cao, Xia ... R01ES007331, R01ES010563 Oncotarget (2017 Oct 17) 29156789 Exiting the NIEHS site 2017 
"Manganese-induced neurotoxicity: a review of its behavioral consequences and neuroprotective strate ...   Peres, Tanara V; Schettinger, Maria Rosa C; Chen, Pan; Carvalho, Fabiano; Avila, Daiana S; Bowm ... R01ES010563 BMC Pharmacol Toxicol (2016 Nov 04) 27814772 Exiting the NIEHS site 2016 
A Simple Light Stimulation of Caenorhabditis elegans.   Lee, Kun He; Aschner, Michael R01ES007331, R01ES010563 Curr Protoc Toxicol (2016 Feb 01) 26828328 Exiting the NIEHS site 2016 
Advanced Glycation End-Products and Their Receptors: Related Pathologies, Recent Therapeutic Strateg ...   Pinkas, Adi; Aschner, Michael R01ES007331, R01ES010563 Chem Res Toxicol (2016 May 16) 27054356 Exiting the NIEHS site 2016 
Autophagy in Neurodegenerative Diseases and Metal Neurotoxicity.   Zhang, Ziyan; Miah, Mahfuzur; Culbreth, Megan; Aschner, Michael R01ES007331, R01ES010563 Neurochem Res (2016 Feb) 26869037 Exiting the NIEHS site 2016 
Caenorhabditis elegans as a model system to study post-translational modifications of human transthy ...   Henze, Andrea; Homann, Thomas; Rohn, Isabelle; Aschner, Michael; Link, Christopher D; Kleuser, ... R01ES007331, R01ES010563 Sci Rep (2016 Nov 21) 27869126 Exiting the NIEHS site 2016 
Cellular uptake of lead in the blood-cerebrospinal fluid barrier: Novel roles of Connexin 43 hemicha ...   Song, Han; Zheng, Gang; Liu, Yang; Shen, Xue-Feng; Zhao, Zai-Hua; Aschner, Michael; Luo, Wen- ... R01ES007331, R01ES010563 Toxicol Appl Pharmacol (2016 Apr 15) 26926986 Exiting the NIEHS site 2016 
Extracellular dopamine and alterations on dopamine transporter are related to reserpine toxicity in ...   Reckziegel, Patrícia; Chen, Pan; Caito, Sam; Gubert, Priscila; Soares, Félix Alexandre Antunes; ... R01ES010563 Arch Toxicol (2016 Mar) 25579234 Exiting the NIEHS site 2016 
Genomic Instability Associated with p53 Knockdown in the Generation of Huntington's Disease Human In ...   Tidball, Andrew M; Neely, M Diana; Chamberlin, Reed; Aboud, Asad A; Kumar, Kevin K; Han, Bingy ... R01ES010563 PLoS One (2016) 26982737 Exiting the NIEHS site 2016 
Guarana (Paullinia cupana Mart.) attenuates methylmercury-induced toxicity in Caenorhabditis elegans ...   Arantes, Leticia Priscilla; Peres, Tanara Vieira; Chen, Pam; Caito, Samuel; Aschner, Michael; S ... R01ES007331, R01ES010563 Toxicol Res (Camb) (2016 Nov 01) 28316775 Exiting the NIEHS site 2016 
Involvement of heat shock proteins on Mn-induced toxicity in Caenorhabditis elegans.   Avila, Daiana Silva; Benedetto, Alexandre; Au, Catherine; Bornhorst, Julia; Aschner, Michael R01ES007331, R01ES010563 BMC Pharmacol Toxicol (2016 Nov 02) 27802836 Exiting the NIEHS site 2016 
Linear and Curvilinear Trajectories of Cortical Loss with Advancing Age and Disease Duration in Park ...   Claassen, Daniel O; Dobolyi, David G; Isaacs, David A; Roman, Olivia C; Herb, Joshua; Wylie, S ... R01ES010563 Aging Dis (2016 May) 27330836 Exiting the NIEHS site 2016 
Manganese and aging.   Parmalee, Nancy L; Aschner, Michael R01ES010563 Neurotoxicology (2016 Sep) 27293182 Exiting the NIEHS site 2016 
Methods for the Detection of Autophagy in Mammalian Cells.   Zhang, Ziyan; Singh, Rajat; Aschner, Michael R01ES007331, R01ES010563 Curr Protoc Toxicol (2016 08 01) 27479363 Exiting the NIEHS site 2016 
Null allele mutants of trt-1, the catalytic subunit of telomerase in Caenorhabditis elegans, are les ...   Ijomone, Omamuyovwi M; Miah, Mahfuzur R; Peres, Tanara V; Nwoha, Polycarp U; Aschner, Michael R01ES010563 Neurotoxicology (2016 Dec) 27593554 Exiting the NIEHS site 2016 
Preconditioning of endoplasmic reticulum stress protects against acrylonitrile-induced cytotoxicity ...   Yu, Bai; Wenjun, Zhao; Changsheng, Yin; Yuntao, Fang; Jing, Ma; Ben, Li; Hai, Qian; Guangwei, ... R01ES007331, R01ES010563 Neurotoxicology (2016 07) 27260289 Exiting the NIEHS site 2016 
Role of autophagy in methylmercury-induced neurotoxicity in rat primary astrocytes.   Yuntao, Fang; Chenjia, Guo; Panpan, Zhang; Wenjun, Zhao; Suhua, Wang; Guangwei, Xing; Haifeng, ... R01ES007331, R01ES010563 Arch Toxicol (2016 Feb) 25488884 Exiting the NIEHS site 2016 
Scavengers of reactive γ-ketoaldehydes extend Caenorhabditis elegans lifespan and healthspan through ...   Nguyen, Thuy T; Caito, Samuel W; Zackert, William E; West, James D; Zhu, Shijun; Aschner, Mich ... R01ES007331, R01ES010563, T32ES007028 Aging (Albany NY) (2016 08) 27514077 Exiting the NIEHS site 2016 
Sex- and structure-specific differences in antioxidant responses to methylmercury during early devel ...   Ruszkiewicz, Joanna A; Bowman, Aaron B; Farina, Marcelo; Rocha, João B T; Aschner, Michael R01ES007331, R01ES010563 Neurotoxicology (2016 Sep) 27456245 Exiting the NIEHS site 2016 
A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuro ...   Tidball, Andrew M; Bryan, Miles R; Uhouse, Michael A; Kumar, Kevin K; Aboud, Asad A; Feist, Ja ... R01ES010563 Hum Mol Genet (2015 Apr 01) 25489053 Exiting the NIEHS site 2015 
Age- and manganese-dependent modulation of dopaminergic phenotypes in a C. elegans DJ-1 genetic mode ...   Chen, Pan; DeWitt, Margaret R; Bornhorst, Julia; Soares, Felix A; Mukhopadhyay, Somshuvra; Bowm ... R01ES007331, R01ES010563 Metallomics (2015 Feb) 25531510 Exiting the NIEHS site 2015 
Combinatorial polymer matrices enhance in vitro maturation of human induced pluripotent stem cell-de ...   Chun, Young Wook; Balikov, Daniel A; Feaster, Tromondae K; Williams, Charles H; Sheng, Calvin C ... R01ES010563 Biomaterials (2015 Oct) 26204225 Exiting the NIEHS site 2015 
Differential interaction of hGDH1 and hGDH2 with manganese: Implications for metabolism and toxicity ...   Dimovasili, Christina; Aschner, Michael; Plaitakis, Andreas; Zaganas, Ioannis R01ES010563 Neurochem Int (2015 Sep) 25837286 Exiting the NIEHS site 2015 
Differential responses of induced pluripotent stem cell-derived cardiomyocytes to anisotropic strain ...   Chun, Young Wook; Voyles, David E; Rath, Rutwik; Hofmeister, Lucas H; Boire, Timothy C; Wilcox, ... R01ES010563 J Biomech (2015 Nov 05) 26476764 Exiting the NIEHS site 2015 
Elemental bioimaging of Cisplatin in Caenorhabditis elegans by LA-ICP-MS.   Crone, Barbara; Aschner, Michael; Schwerdtle, Tanja; Karst, Uwe; Bornhorst, Julia R01ES007331, R01ES010563 Metallomics (2015 Jul) 25996669 Exiting the NIEHS site 2015 
Genetic dys-regulation of astrocytic glutamate transporter EAAT2 and its implications in neurologica ...   Karki, Pratap; Smith, Keisha; Johnson Jr, James; Aschner, Michael; Lee, Eunsook Y R01ES010563 Neurochem Res (2015 Feb) 25064045 Exiting the NIEHS site 2015 
High-Resolution Multi-Photon Imaging of Morphological Structures of Caenorhabditis elegans.   Bixel, Gabriele M; Fretham, Stephanie J B; Aschner, Michael R01ES007331, R01ES010563 Curr Protoc Toxicol (2015 05 04) 26344221 Exiting the NIEHS site 2015 
High-resolution multi-photon imaging of morphological structures of caenorhabditis elegans.   Bixel, M Gabriele; Fretham, Stephanie J B; Aschner, Michael R01ES007331, R01ES010563 Curr Protoc Toxicol (2015 May) 26309451 Exiting the NIEHS site 2015 
Highly sensitive isotope-dilution liquid-chromatography-electrospray ionization-tandem-mass spectrom ...   Schumacher, Fabian; Chakraborty, Sudipta; Kleuser, Burkhard; Gulbins, Erich; Schwerdtle, Tanja; ... R01ES007331, R01ES010563 Talanta (2015 Nov 01) 26452793 Exiting the NIEHS site 2015 
Lead, Arsenic, and Manganese Metal Mixture Exposures: Focus on Biomarkers of Effect.   Andrade, V M; Mateus, M L; Batoréu, M C; Aschner, M; Marreilha dos Santos, A P R01ES010563 Biol Trace Elem Res (2015 Jul) 25693681 Exiting the NIEHS site 2015 
Loss of pdr-1/parkin influences Mn homeostasis through altered ferroportin expression in C. elegans.   Chakraborty, Sudipta; Chen, Pan; Bornhorst, Julia; Schwerdtle, Tanja; Schumacher, Fabian; Kleus ... R01ES007331, R01ES010563 Metallomics (2015 May) 25769119 Exiting the NIEHS site 2015 
Manganese homeostasis in the nervous system.   Chen, Pan; Chakraborty, Sudipta; Mukhopadhyay, Somshuvra; Lee, Eunsook; Paoliello, Monica M B; ... R01ES010563 J Neurochem (2015 Aug) 25982296 Exiting the NIEHS site 2015 
Manganese Is Essential for Neuronal Health.   Horning, Kyle J; Caito, Samuel W; Tipps, K Grace; Bowman, Aaron B; Aschner, Michael R01ES007331, R01ES010563, T32ES007028 Annu Rev Nutr (2015) 25974698 Exiting the NIEHS site 2015 
Manganese-induced Neurotoxicity: From C. elegans to Humans.   Chen, Pan; Chakraborty, Sudipta; Peres, Tanara V; Bowman, Aaron B; Aschner, Michael R01ES007331, R01ES010563 Toxicol Res (Camb) (2015 Mar 01) 25893090 Exiting the NIEHS site 2015 
Manganese-Induced Parkinsonism and Parkinson's Disease: Shared and Distinguishable Features.   Kwakye, Gunnar F; Paoliello, Monica M B; Mukhopadhyay, Somshuvra; Bowman, Aaron B; Aschner, Mic ... R01ES010563 Int J Environ Res Public Health (2015 Jul 06) 26154659 Exiting the NIEHS site 2015 
Mir-203-mediated tricellulin mediates lead-induced in vitro loss of blood-cerebrospinal fluid barrie ...   Su, Peng; Zhao, Fang; Cao, Zipeng; Zhang, Jianbin; Aschner, Michael; Luo, Wenjing R01ES007331, R01ES010563 Toxicol In Vitro (2015 Aug) 25975750 Exiting the NIEHS site 2015 
Mitochondrial Redox Dysfunction and Environmental Exposures.   Caito, Samuel W; Aschner, Michael R01ES007331, R01ES010563 Antioxid Redox Signal (2015 Aug 20) 25826672 Exiting the NIEHS site 2015 
Neuroimaging identifies increased manganese deposition in infants receiving parenteral nutrition.   Aschner, Judy L; Anderson, Adam; Slaughter, James Christopher; Aschner, Michael; Steele, Steven ... R01ES010563 Am J Clin Nutr (2015 Dec) 26561627 Exiting the NIEHS site 2015 
New tools for the quantitative assessment of prodrug delivery and neurotoxicity.   Samuelson, Lynn E; Scherer, Randy L; VanSaun, Michael N; Fan, Kang-Hsien; Dozier, E Ashley; Car ... R01ES007331, R01ES010563 Neurotoxicology (2015 Mar) 25732874 Exiting the NIEHS site 2015 
PARK2 patient neuroprogenitors show increased mitochondrial sensitivity to copper.   Aboud, Asad A; Tidball, Andrew M; Kumar, Kevin K; Neely, M Diana; Han, Bingying; Ess, Kevin C; ... R01ES010563 Neurobiol Dis (2015 Jan) 25315681 Exiting the NIEHS site 2015 
Protective effects of novel organic selenium compounds against oxidative stress in the nematode Caen ...   Stefanello, Sílvio Terra; Gubert, Priscila; Puntel, Bruna; Mizdal, Caren Rigon; de Campos, Marl ... R01ES007331, R01ES010563 Toxicol Rep (2015) 26726309 Exiting the NIEHS site 2015 
Quantification of Glutathione in Caenorhabditis elegans.   Caito, Samuel W; Aschner, Michael R01ES007331, R01ES010563 Curr Protoc Toxicol (2015) 26309452 Exiting the NIEHS site 2015 
Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic ...   Brown, Jacquelyn A; Pensabene, Virginia; Markov, Dmitry A; Allwardt, Vanessa; Neely, M Diana; S ... R01ES010563 Biomicrofluidics (2015 Sep) 26576206 Exiting the NIEHS site 2015 
RNASeq in C. elegans Following Manganese Exposure.   Parmalee, Nancy L; Maqbool, Shahina B; Ye, Bin; Calder, Brent; Bowman, Aaron B; Aschner, Micha ... R01ES007331, R01ES010563 Curr Protoc Toxicol (2015 Aug 06) 26250396 Exiting the NIEHS site 2015 
Role of transcription factor yin yang 1 in manganese-induced reduction of astrocytic glutamate trans ...   Karki, Pratap; Smith, Keisha; Johnson Jr, James; Aschner, Michael; Lee, Eunsook R01ES010563 Neurochem Int (2015 Sep) 25128239 Exiting the NIEHS site 2015 
SLC30A10: A novel manganese transporter.   Chen, Pan; Bowman, Aaron B; Mukhopadhyay, Somshuvra; Aschner, Michael R01ES010563 Worm (2015 Jul-Sep) 26430566 Exiting the NIEHS site 2015 
Structural and functional changes in the zebrafish (Danio rerio) skeletal muscle after cadmium expos ...   Avallone, Bice; Agnisola, Claudio; Cerciello, Raimondo; Panzuto, Raffaele; Simoniello, Palma; C ... R01ES010563 Cell Biol Toxicol (2015 Dec) 26715392 Exiting the NIEHS site 2015 
Transcriptional Regulation of the Astrocytic Excitatory Amino Acid Transporter 1 (EAAT1) via NF-κB a ...   Karki, Pratap; Kim, Clifford; Smith, Keisha; Son, Deok-Soo; Aschner, Michael; Lee, Eunsook R01ES007331, R01ES010563 J Biol Chem (2015 Sep 25) 26269591 Exiting the NIEHS site 2015 
Untargeted metabolic profiling identifies interactions between Huntington's disease and neuronal man ...   Kumar, Kevin K; Goodwin, Cody R; Uhouse, Michael A; Bornhorst, Julia; Schwerdtle, Tanja; Aschne ... R01ES010563 Metallomics (2015 Feb) 25599126 Exiting the NIEHS site 2015 
Activation of MAPK and FoxO by manganese (Mn) in rat neonatal primary astrocyte cultures.   Exil, Vernat; Ping, Li; Yu, Yingchun; Chakraborty, Sudipta; Caito, Samuel W; Wells, K Sam; Kar ... R01ES010563 PLoS One (2014) 24787138 Exiting the NIEHS site 2014 
Anthocyanin-rich açaí (Euterpe oleracea Mart.) extract attenuates manganese-induced oxidative stress ...   da Silva Santos, Vivian; Bisen-Hersh, Emily; Yu, Yingchun; Cabral, Ingridy Simone Ribeiro; Nardi ... R01ES010563 J Toxicol Environ Health A (2014) 24617543 Exiting the NIEHS site 2014 
Arsenic and manganese alter lead deposition in the rat.   Andrade, V; Mateus, M L; Santos, D; Aschner, M; Batoreu, M C; Marreilha dos Santos, A P R01ES010563 Biol Trace Elem Res (2014 Jun) 24715659 Exiting the NIEHS site 2014 
Cellular manganese content is developmentally regulated in human dopaminergic neurons.   Kumar, Kevin K; Lowe Jr, Edward W; Aboud, Asad A; Neely, M Diana; Redha, Rey; Bauer, Joshua A; ... R01ES010563 Sci Rep (2014 Oct 28) 25348053 Exiting the NIEHS site 2014 
Changes in rat urinary porphyrin profiles predict the magnitude of the neurotoxic effects induced by ...   Andrade, Vanda; Mateus, M Luísa; Batoréu, M Camila; Aschner, Michael; Marreilha dos Santos, A P R01ES010563 Neurotoxicology (2014 Dec) 25451970 Exiting the NIEHS site 2014 
Considerations on manganese (Mn) treatments for in vitro studies.   Bowman, Aaron B; Aschner, Michael R01ES010563 Neurotoxicology (2014 Mar) 24509086 Exiting the NIEHS site 2014 
Elemental bioimaging of manganese uptake in C. elegans.   Brinkhaus, Sigrid Grosse; Bornhorst, Julia; Chakraborty, Sudipta; Wehe, Christoph A; Niehaus, R ... R01ES007331, R01ES010563 Metallomics (2014 Mar) 24481269 Exiting the NIEHS site 2014 
F3-Isoprostanes as a Measure of in vivo Oxidative Damage in Caenorhabditis elegans.   Nguyen, Thuy T; Aschner, Michael R01ES007331, R01ES010563 Curr Protoc Toxicol (2014 Nov 06) 25378241 Exiting the NIEHS site 2014 
Manganese in human parenteral nutrition: considerations for toxicity and biomonitoring.   Santos, Dinamene; Batoreu, Camila; Mateus, Luisa; Marreilha Dos Santos, A P; Aschner, Michael R01ES010563 Neurotoxicology (2014 Jul) 24184781 Exiting the NIEHS site 2014 
Recent Advances in Mercury Research.   Martinez-Finley, Ebany J; Aschner, Michael R01ES007331, R01ES010563 Curr Environ Health Rep (2014 Jun) 28018837 Exiting the NIEHS site 2014 
SLC30A10 is a cell surface-localized manganese efflux transporter, and parkinsonism-causing mutation ...   Leyva-Illades, Dinorah; Chen, Pan; Zogzas, Charles E; Hutchens, Steven; Mercado, Jonathan M; Sw ... R01ES007331, R01ES010563 J Neurosci (2014 Oct 15) 25319704 Exiting the NIEHS site 2014 
The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein ...   Bornhorst, Julia; Chakraborty, Sudipta; Meyer, Sören; Lohren, Hanna; Brinkhaus, Sigrid Grosse; ... R01ES010563, T32ES007028 Metallomics (2014 Mar) 24452053 Exiting the NIEHS site 2014 
The interaction between microglia and neural stem/precursor cells.   Su, Peng; Zhang, Jianbin; Zhao, Fang; Aschner, Michael; Chen, Jingyuan; Luo, Wenjing R01ES007331, R01ES010563 Brain Res Bull (2014 Oct) 25245208 Exiting the NIEHS site 2014 
Yin Yang 1 is a repressor of glutamate transporter EAAT2, and it mediates manganese-induced decrease ...   Karki, Pratap; Webb, Anton; Smith, Keisha; Johnson Jr, James; Lee, Kyuwon; Son, Deok-Soo; Asch ... R01ES010563 Mol Cell Biol (2014 Apr) 24469401 Exiting the NIEHS site 2014 
Acrylonitrile has Distinct Hormetic Effects on Acetyl-Cholinesterase Activity in Mouse Brain and Blo ...   Yuanqing, He; Suhua, Wang; Guangwei, Xing; Chunlan, Ren; Hai, Qian; Wenrong, Xu; Rongzhu, Lu; ... R01ES007331, R01ES010563 Dose Response (2013) 23550232 Exiting the NIEHS site 2013 
cAMP response element-binding protein (CREB) and nuclear factor κB mediate the tamoxifen-induced up- ...   Karki, Pratap; Webb, Anton; Smith, Keisha; Lee, Kyuwon; Son, Deok-Soo; Aschner, Michael; Lee, ... R01ES010563 J Biol Chem (2013 Oct 04) 23955341 Exiting the NIEHS site 2013 
Chlorpyrifos-, diisopropylphosphorofluoridate-, and parathion-induced behavioral and oxidative stres ...   López-Granero, Caridad; Cañadas, Fernando; Cardona, Diana; Yu, Yingchun; Giménez, Estela; Lozan ... R01ES007331, R01ES010563 Toxicol Sci (2013 Jan) 22986948 Exiting the NIEHS site 2013 
Comparative study on methyl- and ethylmercury-induced toxicity in C6 glioma cells and the potential ...   Zimmermann, Luciana T; Santos, Danúbia B; Naime, Aline A; Leal, Rodrigo B; Dórea, José G; Barbo ... R01ES007331, R01ES010563 Neurotoxicology (2013 Sep) 23727015 Exiting the NIEHS site 2013 
Comparison between 5-aminosalicylic acid (5-ASA) and para-aminosalicylic acid (4-PAS) as potential p ...   Santos, Dinamene; Batoreu, M Camila; Aschner, Michael; Marreilha dos Santos, Ana P R01ES010563 Biol Trace Elem Res (2013 Apr) 23315311 Exiting the NIEHS site 2013 
Differential response to acrylonitrile toxicity in rat primary astrocytes and microglia.   Caito, Samuel; Yu, Yingchun; Aschner, Michael R01ES007331, R01ES010563, T32ES007028 Neurotoxicology (2013 Jul) 23628792 Exiting the NIEHS site 2013 
Dopaminergic neurotoxicity of S-ethyl N,N-dipropylthiocarbamate (EPTC), molinate, and S-methyl-N,N-d ...   Caito, Samuel W; Valentine, William M; Aschner, Michael R01ES007331, R01ES010563, T32ES007028 J Neurochem (2013 Dec) 23786526 Exiting the NIEHS site 2013 
Estrogen attenuates manganese-induced glutamate transporter impairment in rat primary astrocytes.   Lee, Eunsook; Sidoryk-Wegrzynowicz, Marta; Farina, Marcelo; Rocha, Joao B T; Aschner, Michael R01ES010563 Neurotox Res (2013 Feb) 22878846 Exiting the NIEHS site 2013 
Evaluation of neurobehavioral and neuroinflammatory end-points in the post-exposure period in rats s ...   Santos, Dinamene; Dinamene, Santos; Batoréu, M Camila; Camila, Batoreu M; Tavares de Almeida, I ... R01ES010563 Toxicology (2013 Dec 06) 24060432 Exiting the NIEHS site 2013 
Hormetic effects of acute methylmercury exposure on grp78 expression in rat brain cortex.   Zhang, Ye; Lu, Rongzhu; Liu, Wenshuai; Wu, Ying; Qian, Hai; Zhao, Xiaowu; Wang, Suhua; Xing, ... R01ES007331, R01ES010563 Dose Response (2013) 23549286 Exiting the NIEHS site 2013 
In vitro manganese exposure disrupts MAPK signaling pathways in striatal and hippocampal slices from ...   Peres, Tanara Vieira; Pedro, Daniela Zótico; de Cordova, Fabiano Mendes; Lopes, Mark William; Go ... R01ES010563 Biomed Res Int (2013) 24324973 Exiting the NIEHS site 2013 
Manganese efflux in Parkinsonism: insights from newly characterized SLC30A10 mutations.   DeWitt, Margaret R; Chen, Pan; Aschner, Michael R01ES010563, T32ES007028 Biochem Biophys Res Commun (2013 Mar 01) 23357421 Exiting the NIEHS site 2013 
Manganese homeostasis and transport.   Roth, Jerome; Ponzoni, Silvia; Aschner, Michael R01ES007331, R01ES010563 Met Ions Life Sci (2013) 23595673 Exiting the NIEHS site 2013 
Manganese in health and disease.   Avila, Daiana Silva; Puntel, Robson Luiz; Aschner, Michael R01ES007331, R01ES010563 Met Ions Life Sci (2013) 24470093 Exiting the NIEHS site 2013 
Manganese neurotoxicity and the role of reactive oxygen species.   Martinez-Finley, Ebany J; Gavin, Claire E; Aschner, Michael; Gunter, Thomas E R01ES010563, T32ES007028 Free Radic Biol Med (2013 Sep) 23395780 Exiting the NIEHS site 2013 
Manganese neurotoxicity may underlie the association between early life iron deficiency and impaired ...   Maitre, Nathalie L; Aschner, Judy L; Aschner, Michael R01ES010563 J Nutr (2013 Apr) 23515251 Exiting the NIEHS site 2013 
Manganese neurotoxicity: a focus on glutamate transporters.   Karki, Pratap; Lee, Eunsook; Aschner, Michael R01ES010563 Ann Occup Environ Med (2013 May 21) 24472696 Exiting the NIEHS site 2013 
Manganese toxicity in the central nervous system: the glutamine/glutamate-ýý-aminobutyric acid cycle ...   Sidoryk-Wegrzynowicz, M; Aschner, M R01ES010563 J Intern Med (2013 May) 23360507 Exiting the NIEHS site 2013 
Manganese-exposed developing rats display motor deficits and striatal oxidative stress that are reve ...   Cordova, Fabiano M; Aguiar Jr, Aderbal S; Peres, Tanara V; Lopes, Mark W; Gonçalves, Filipe M; ... R01ES007331, R01ES010563 Arch Toxicol (2013 Jul) 23385959 Exiting the NIEHS site 2013 
Metal-induced neurodegeneration in C. elegans.   Chen, Pan; Martinez-Finley, Ebany J; Bornhorst, Julia; Chakraborty, Sudipta; Aschner, Michael R01ES010563, T32ES007028 Front Aging Neurosci (2013) 23730287 Exiting the NIEHS site 2013 
Metals, oxidative stress and neurodegeneration: a focus on iron, manganese and mercury.   Farina, Marcelo; Avila, Daiana Silva; da Rocha, Joao Batista Teixeira; Aschner, Michael R01ES007331, R01ES010563 Neurochem Int (2013 Apr) 23266600 Exiting the NIEHS site 2013 
Optimization of fluorescence assay of cellular manganese status for high throughput screening.   Kumar, Kevin K; Aboud, Asad A; Patel, Devin K; Aschner, Michael; Bowman, Aaron B R01ES010563 J Biochem Mol Toxicol (2013 Jan) 23169769 Exiting the NIEHS site 2013 
Organochalcogens inhibit mitochondrial complexes I and II in rat brain: possible implications for ne ...   Puntel, Robson Luiz; Roos, Daniel Henrique; Seeger, Rodrigo Lopes; Aschner, Michael; Rocha, Joã ... R01ES007331, R01ES010563 Neurotox Res (2013 Aug) 23224748 Exiting the NIEHS site 2013 
Oxidative stress mechanisms underlying Parkinson's disease-associated neurodegeneration in C. elegan ...   Chakraborty, Sudipta; Bornhorst, Julia; Nguyen, Thuy T; Aschner, Michael R01ES007331, R01ES010563, T32ES007028 Int J Mol Sci (2013 Nov 21) 24284401 Exiting the NIEHS site 2013 
Role of astrocytes in manganese mediated neurotoxicity.   Sidoryk-Wegrzynowicz, Marta; Aschner, Michael R01ES010563 BMC Pharmacol Toxicol (2013) 23594835 Exiting the NIEHS site 2013 
SyM-BBB: a microfluidic Blood Brain Barrier model.   Prabhakarpandian, Balabhaskar; Shen, Ming-Che; Nichols, Joseph B; Mills, Ivy R; Sidoryk-Wegrzyno ... R01ES007331, R01ES010563 Lab Chip (2013 Mar 21) 23344641 Exiting the NIEHS site 2013 
Urinary delta-ALA: a potential biomarker of exposure and neurotoxic effect in rats co-treated with a ...   Andrade, Vanda; Mateus, M Luísa; Batoréu, M Camila; Aschner, Michael; dos Santos, A P Marreilha R01ES010563 Neurotoxicology (2013 Sep) 23764341 Exiting the NIEHS site 2013 
15-Deoxy-Δ12,14-prostaglandin J₂ modulates manganese-induced activation of the NF-κB, Nrf2, and PI3K ...   Lee, Eunsook; Yin, Zhaobao; Sidoryk-Węgrzynowicz, Marta; Jiang, Haiyan; Aschner, Michael R01ES010563 Free Radic Biol Med (2012 Mar 15) 22245093 Exiting the NIEHS site 2012 
Ammonia increases paracellular permeability of rat brain endothelial cells by a mechanism encompassi ...   Skowrońska, Marta; Zielińska, Magdalena; Wójcik-Stanaszek, Luiza; Ruszkiewicz, Joanna; Milatovic ... R01ES007331, R01ES010563 J Neurochem (2012 Apr) 22260250 Exiting the NIEHS site 2012 
Anti-aging effects of deuterium depletion on Mn-induced toxicity in a C. elegans model.   Avila, Daiana Silva; Somlyai, Gábor; Somlyai, Ildikó; Aschner, Michael R01ES007331, R01ES010563 Toxicol Lett (2012 Jun 20) 22561170 Exiting the NIEHS site 2012 
C. elegans and Neurodegeneration In Caenorhabditis Elegans: Anatomy, Life Cycles and Biological Func ...   Martinez-Finley, Ebany J; Chakraborty, Sudipta; Caito, Sam; Fretham, Stephanie; Aschner, Michae ... R01ES007331, R01ES010563 Adv Med Biol (2012) 32346495 Exiting the NIEHS site 2012 
Cellular transport and homeostasis of essential and nonessential metals.   Martinez-Finley, Ebany J; Chakraborty, Sudipta; Fretham, Stephanie J B; Aschner, Michael R01ES007331, R01ES010563, T32ES007028 Metallomics (2012 Jul) 22337135 Exiting the NIEHS site 2012 
Current needs and future directions of occupational safety and heath in a globalized world.   Perera, Frederica P; Li, T Y; Lin, C; Tang, Deliang; Gilbert, Steven G; Kang, Seong-Kyu; Aschn ... R01ES007331, R01ES010563 Neurotoxicology (2012 Aug) 22037493 Exiting the NIEHS site 2012 
Disease-toxicant interactions in manganese exposed Huntington disease mice: early changes in striata ...   Madison, Jennifer L; Wegrzynowicz, Michal; Aschner, Michael; Bowman, Aaron B R01ES010563 PLoS One (2012) 22363539 Exiting the NIEHS site 2012 
Genome-Wide Analyses of Metal Responsive Genes in Caenorhabditis elegans.   Caito, Samuel; Fretham, Stephanie; Martinez-Finley, Ebany; Chakraborty, Sudipta; Avila, Daiana; ... R01ES007331, R01ES010563, T32ES007028 Front Genet (2012) 22514555 Exiting the NIEHS site 2012 
GPR30 regulates glutamate transporter GLT-1 expression in rat primary astrocytes.   Lee, Eunsook; Sidoryk-Wêgrzynowicz, Marta; Wang, Ning; Webb, Anton; Son, Deok-Soo; Lee, Kyuwon ... R01ES010563 J Biol Chem (2012 Aug 03) 22645130 Exiting the NIEHS site 2012 
In vivo manganese exposure modulates Erk, Akt and Darpp-32 in the striatum of developing rats, and i ...   Cordova, Fabiano M; Aguiar Jr, Aderbal S; Peres, Tanara V; Lopes, Mark W; Gonçalves, Filipe M; ... R01ES010563 PLoS One (2012) 22427945 Exiting the NIEHS site 2012 
Manganese alters rat brain amino acids levels.   Santos, Dinamene; Batoreu, M Camila; Almeida, Isabel; Ramos, Ruben; Sidoryk-Wegrzynowicz, M; As ... R01ES010563 Biol Trace Elem Res (2012 Dec) 22971893 Exiting the NIEHS site 2012 
Mechanism of Mn(II)-mediated dysregulation of glutamine-glutamate cycle: focus on glutamate turnover ...   Sidoryk-Wegrzynowicz, Marta; Lee, Eunsook; Aschner, Michael R01ES010563 J Neurochem (2012 Aug) 22708868 Exiting the NIEHS site 2012 
Mechanisms and Modifiers of Methylmercury-Induced Neurotoxicity.   Fretham, Stephanie Jb; Caito, Samuel; Martinez-Finley, Ebany J; Aschner, Michael R01ES007331, R01ES010563, T32ES007028 Toxicol Res (Camb) (2012 Jul 01) 27795823 Exiting the NIEHS site 2012 
New strategies in neuroprotection and neurorepair.   Antonelli, Marta C; Guillemin, Gilles J; Raisman-Vozari, Rita; Del-Bel, Elaine A; Aschner, Mich ... R01ES007331, R01ES010563 Neurotox Res (2012 Jan) 21861211 Exiting the NIEHS site 2012 
Organotellurium and organoselenium compounds attenuate Mn-induced toxicity in Caenorhabditis elegans ...   Avila, Daiana Silva; Benedetto, Alexandre; Au, Catherine; Manarin, Flávia; Erikson, Keith; Soar ... R01ES007331, R01ES010563 Free Radic Biol Med (2012 May 01) 22406322 Exiting the NIEHS site 2012 
Pathophysiology of manganese-associated neurotoxicity.   Racette, Brad A; Aschner, Michael; Guilarte, Tomas R; Dydak, Ulrike; Criswell, Susan R; Zheng, ... R01ES010563 Neurotoxicology (2012 Aug) 22202748 Exiting the NIEHS site 2012 
Prolonged hypoxia augments L-citrulline transport by system A in the newborn piglet pulmonary circul ...   Fike, Candice D; Sidoryk-Wegrzynowicz, Marta; Aschner, Michael; Summar, Marshall; Prince, Lawre ... R01ES007331, R01ES010563 Cardiovasc Res (2012 Aug 01) 22673370 Exiting the NIEHS site 2012 
Protective effects of ebselen (Ebs) and para-aminosalicylic acid (PAS) against manganese (Mn)-induce ...   Santos, A P Marreilha Dos; Lucas, Rui L; Andrade, Vanda; Mateus, M Luisa; Milatovic, Dejan; Asc ... R01ES010563 Toxicol Appl Pharmacol (2012 Feb 1) 22178737 Exiting the NIEHS site 2012 
The Caenorhabiditis elegans model as a reliable tool in neurotoxicology.   Avila, Daiana; Helmcke, Kirsten; Aschner, Michael R01ES007331, R01ES010563 Hum Exp Toxicol (2012 Mar) 21148196 Exiting the NIEHS site 2012 
The inhibitory effect of manganese on acetylcholinesterase activity enhances oxidative stress and ne ...   Santos, Dinamene; Milatovic, Dejan; Andrade, Vanda; Batoreu, M Camila; Aschner, Michael; Marrei ... R01ES010563 Toxicology (2012 Feb 26) 22154916 Exiting the NIEHS site 2012 
Transforming growth factor-α mediates estrogen-induced upregulation of glutamate transporter GLT-1 i ...   Lee, Eunsook; Sidoryk-Wegrzynowicz, Marta; Yin, Zhaobao; Webb, Anton; Son, Deok-Soo; Aschner, ... R01ES010563 Glia (2012 Jul) 22488924 Exiting the NIEHS site 2012 
Disruption of astrocytic glutamine turnover by manganese is mediated by the protein kinase C pathway ...   Sidoryk-Wegrzynowicz, Marta; Lee, Eunsook; Mingwei, Ni; Aschner, Michael R01ES010563 Glia (2011 Nov) 21812036 Exiting the NIEHS site 2011 
Environmental exposure, obesity, and Parkinson's disease: lessons from fat and old worms.   Aitlhadj, Layla; Avila, Daiana Silva; Benedetto, Alexandre; Aschner, Michael; Stürzenbaum, Step ... R01ES010563 Environ Health Perspect (2011 Jan) 20797931 Exiting the NIEHS site 2011 
Gender and manganese exposure interactions on mouse striatal neuron morphology.   Madison, Jennifer L; Wegrzynowicz, Michal; Aschner, Michael; Bowman, Aaron B R01ES010563 Neurotoxicology (2011 Dec) 21641932 Exiting the NIEHS site 2011 
Insights from Caenorhabditis elegans on the role of metals in neurodegenerative diseases.   Martinez-Finley, Ebany J; Avila, Daiana Silva; Chakraborty, Sudipta; Aschner, Michael R01ES007331, R01ES010563, T32ES007028 Metallomics (2011 Mar) 21210060 Exiting the NIEHS site 2011 
Measurement of isoprostanes as markers of oxidative stress.   Milatovic, Dejan; Montine, Thomas J; Aschner, Michael R01ES007331, R01ES010563 Methods Mol Biol (2011) 21815067 Exiting the NIEHS site 2011 
Mefloquine neurotoxicity is mediated by non-receptor tyrosine kinase.   Milatovic, Dejan; Jenkins, Jerry W; Hood, Jonathan E; Yu, Yingchun; Rongzhu, Lu; Aschner, Mich ... R01ES007331, R01ES010563, T32ES007028 Neurotoxicology (2011 Oct) 21241737 Exiting the NIEHS site 2011 
Prolactin is a peripheral marker of manganese neurotoxicity.   Marreilha Dos Santos, A P; Lopes Santos, M; Batoréu, Maria C; Aschner, M R01ES010563 Brain Res (2011 Mar 25) 21262206 Exiting the NIEHS site 2011 
Prostanoid signaling: dual role for prostaglandin E2 in neurotoxicity.   Milatovic, Dejan; Montine, Thomas J; Aschner, Michael R01ES007331, R01ES010563 Neurotoxicology (2011 Jun) 21376752 Exiting the NIEHS site 2011 
Protective effects of antioxidants and anti-inflammatory agents against manganese-induced oxidative ...   Milatovic, Dejan; Gupta, Ramesh C; Yu, Yingchun; Zaja-Milatovic, Snjezana; Aschner, Michael R01ES010563 Toxicol Appl Pharmacol (2011 Nov 01) 21684300 Exiting the NIEHS site 2011 
Role of astrocytes in brain function and disease.   Sidoryk-Wegrzynowicz, Marta; Wegrzynowicz, Michal; Lee, Eunsook; Bowman, Aaron B; Aschner, Mich ... R01ES010563 Toxicol Pathol (2011 Jan) 21075920 Exiting the NIEHS site 2011 
Role of manganese in neurodegenerative diseases.   Bowman, Aaron B; Kwakye, Gunnar F; Herrero Hernández, Elena; Aschner, Michael R01ES010563 J Trace Elem Med Biol (2011 Dec) 21963226 Exiting the NIEHS site 2011 
Volume measurements in cultured primary astrocytes.   Aschner, Michael R01ES007331, R01ES010563 Methods Mol Biol (2011) 21815080 Exiting the NIEHS site 2011 
γ-Glutamylcysteine ameliorates oxidative injury in neurons and astrocytes in vitro and increases bra ...   Le, Truc M; Jiang, Haiyan; Cunningham, Gary R; Magarik, Jordan A; Barge, William S; Cato, Mari ... R01ES007331, R01ES010563 Neurotoxicology (2011 Oct) 21159318 Exiting the NIEHS site 2011 
Altered manganese homeostasis and manganese toxicity in a Huntington's disease striatal cell model a ...   Williams, B Blairanne; Kwakye, Gunnar F; Wegrzynowicz, Michal; Li, Daphne; Aschner, Michael; Er ... R01ES010563 Toxicol Sci (2010 Sep) 20547568 Exiting the NIEHS site 2010 
Chronic exposure to manganese alters brain responses to amphetamine: a pharmacological magnetic reso ...   Williams, Jason M; Milatovic, Dejan; Gore, John C; Aschner, Michael; Avison, Malcolm J R01ES010563 Toxicol Sci (2010 Apr) 20061340 Exiting the NIEHS site 2010 
Disease-toxicant screen reveals a neuroprotective interaction between Huntington's disease and manga ...   Williams, B Blairanne; Li, Daphne; Wegrzynowicz, Michal; Vadodaria, Bhavin K; Anderson, Joel G; ... R01ES010563 J Neurochem (2010 Jan) 19845833 Exiting the NIEHS site 2010 
Extracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic ...   Benedetto, Alexandre; Au, Catherine; Avila, Daiana Silva; Milatovic, Dejan; Aschner, Michael R01ES010563 PLoS Genet (2010 Aug 26) 20865164 Exiting the NIEHS site 2010 
Ferroportin is a manganese-responsive protein that decreases manganese cytotoxicity and accumulation ...   Yin, Zhaobao; Jiang, Haiyan; Lee, Eun-Sook Y; Ni, Mingwei; Erikson, Keith M; Milatovic, Dejan; ... R01ES010563 J Neurochem (2010 Mar) 20002294 Exiting the NIEHS site 2010 
Gene-environment interactions: neurodegeneration in non-mammals and mammals.   Aschner, Michael; Levin, Edward D; Suñol, Cristina; Olopade, James O; Helmcke, Kirsten J; Avila ... P42ES010356, R01ES007331, R01ES010563 Neurotoxicology (2010 Sep) 20359493 Exiting the NIEHS site 2010 
Hormetic effect of methylmercury on Caenorhabditis elegans.   Helmcke, Kirsten J; Aschner, Michael R01ES007331, R01ES010563, T32ES007028 Toxicol Appl Pharmacol (2010 Oct 15) 20691719 Exiting the NIEHS site 2010 
Introduction to the special issue on emerging high throughput and complementary model screens for ne ...   Aschner, M; Crofton, K M; Levin, E D P42ES010356, R01ES010563 Neurotoxicol Teratol (2010 Jan-Feb) 19703556 Exiting the NIEHS site 2010 
Manganese (Mn) and iron (Fe): interdependency of transport and regulation.   Fitsanakis, Vanessa A; Zhang, Na; Garcia, Stephanie; Aschner, Michael R01ES010563 Neurotox Res (2010 Aug) 19921534 Exiting the NIEHS site 2010 
Manganese-induced downregulation of astroglial glutamine transporter SNAT3 involves ubiquitin-mediat ...   Sidoryk-Wegrzynowicz, Marta; Lee, Eun-Sook; Ni, Mingwei; Aschner, Michael R01ES007331, R01ES010563 Glia (2010 Dec) 20737472 Exiting the NIEHS site 2010 
Morphometric analysis in neurodegenerative disorders.   Milatovic, Dejan; Montine, Thomas J; Zaja-Milatovic, Snjezana; Madison, Jennifer L; Bowman, Aar ... R01ES007331, R01ES010563 Curr Protoc Toxicol (2010 Nov) 21049492 Exiting the NIEHS site 2010 
Morphometric analysis in neurodegenerative disorders.   Milatovic, Dejan; Montine, Thomas J; Zaja-Milatovic, Snjezana; Madison, Jennifer L; Bowman, Aar ... R01ES007331, R01ES010563 Curr Protoc Toxicol (2010 Feb) 20401325 Exiting the NIEHS site 2010 
Neonatal rat primary microglia: isolation, culturing, and selected applications.   Ni, Mingwei; Aschner, Michael R01ES007331, R01ES010563 Curr Protoc Toxicol (2010 Feb) 20960423 Exiting the NIEHS site 2010 
Rat brain endothelial cells are a target of manganese toxicity.   dos Santos, Ana Paula Marreilha; Milatovic, Dejan; Au, Catherine; Yin, Zhaobao; Batoreu, Maria ... R01ES010563 Brain Res (2010 Apr 22) 20170646 Exiting the NIEHS site 2010 
Stressed-induced TMEM135 protein is part of a conserved genetic network involved in fat storage and ...   Exil, Vernat J; Silva Avila, Daiana; Benedetto, Alexandre; Exil, Elizabeth A; Adams, Margaret R ... R01ES010563 PLoS One (2010 Dec 03) 21151927 Exiting the NIEHS site 2010 
A chronic iron-deficient/high-manganese diet in rodents results in increased brain oxidative stress ...   Fitsanakis, Vanessa A; Thompson, Kimberly N; Deery, Sarah E; Milatovic, Dejan; Shihabi, Zak K; ... R01ES010563 Neurotox Res (2009 Feb) 19384579 Exiting the NIEHS site 2009 
A model for the analysis of competitive relaxation effects of manganese and iron in vivo.   Zhang, Na; Fitsanakis, Vanessa A; Erikson, Keith M; Aschner, Michael; Avison, Malcolm J; Gore, ... R01ES007331, R01ES010563 NMR Biomed (2009 May) 19137511 Exiting the NIEHS site 2009 
Changes in Dietary Iron Levels Affect Brain Manganese Accumulation and Distribution.   Fitsanakis, Vanessa A; Finkelstein, Yoram; Aschner, Michael R01ES010563 Cell Biol Toxicol (2009) 32390688 Exiting the NIEHS site 2009 
Estrogen and tamoxifen reverse manganese-induced glutamate transporter impairment in astrocytes.   Lee, Eun-Sook Y; Sidoryk, Marta; Jiang, Haiyan; Yin, Zhaobao; Aschner, Michael R01ES010563 J Neurochem (2009 Jul) 19453300 Exiting the NIEHS site 2009 
Genetic aspects of behavioral neurotoxicology.   Levin, Edward D; Aschner, Michael; Heberlein, Ulrike; Ruden, Douglas; Welsh-Bohmer, Kathleen A; ... P42ES010356, R01ES010563 Neurotoxicology (2009 Sep) 19647018 Exiting the NIEHS site 2009 
Manganese disrupts astrocyte glutamine transporter expression and function.   Sidoryk-Wegrzynowicz, Marta; Lee, Eunsook; Albrecht, Jan; Aschner, Michael R01ES010563 J Neurochem (2009 Aug) 19457077 Exiting the NIEHS site 2009 
Manganese exposure is cytotoxic and alters dopaminergic and GABAergic neurons within the basal gangl ...   Stanwood, Gregg D; Leitch, Duncan B; Savchenko, Valentina; Wu, Jane; Fitsanakis, Vanessa A; And ... R01ES010563 J Neurochem (2009 Jul) 19457100 Exiting the NIEHS site 2009 
Methamphetamine Dysregulates Redox Status in Primary Rat Astrocyte and Mesencephalic Neuronal Cultur ...   Ali, S F; Jiang, H; Rongzhu, L; Milatovic, D; Aschner, M R01ES007331, R01ES010563 Am J Neuroprot Neuroregen (2009 Jun) 30627316 Exiting the NIEHS site 2009 
Oxidative damage and neurodegeneration in manganese-induced neurotoxicity.   Milatovic, Dejan; Zaja-Milatovic, Snjezana; Gupta, Ramesh C; Yu, Yingchun; Aschner, Michael R01ES010563 Toxicol Appl Pharmacol (2009 Oct 15) 19607852 Exiting the NIEHS site 2009 
SMF-1, SMF-2 and SMF-3 DMT1 orthologues regulate and are regulated differentially by manganese level ...   Au, Catherine; Benedetto, Alexandre; Anderson, Joel; Labrousse, Arnaud; Erikson, Keith; Ewbank, ... R01ES010563 PLoS One (2009 Nov 18) 19924247 Exiting the NIEHS site 2009 
The divalent metal transporter homologues SMF-1/2 mediate dopamine neuron sensitivity in caenorhabdi ...   Settivari, Raja; Levora, Jennifer; Nass, Richard R01ES010563 J Biol Chem (2009 Dec 18) 19801673 Exiting the NIEHS site 2009 
Antioxidant properties of blirubin in the model organism, Caenorhabditis elegans.   McCaughan, Danny; Au, Catherine; Benedetto, Alexandre; Milatovic, Dejan; Aschner, Judy; Aschner ... R01ES007331, R01ES010563 Int J Neuroprot Neuroregener (2008) 31178919 Exiting the NIEHS site 2008 
Differential deposition of manganese in the rat brain following subchronic exposure to manganese: a ...   Finkelstein, Yoram; Zhang, Na; Fitsanakis, Vanessa A; Avison, Malcolm J; Gore, John C; Aschner, ... R01ES010563 Isr Med Assoc J (2008 Nov) 19070289 Exiting the NIEHS site 2008 
Leaching of trace elements from biological tissue by formalin fixation.   Gellein, Kristin; Flaten, Trond Peder; Erikson, Keith M; Aschner, Michael; Syversen, Tore R01ES010563 Biol Trace Elem Res (2008 Mar) 17952381 Exiting the NIEHS site 2008 
Manganese transport in eukaryotes: the role of DMT1.   Au, Catherine; Benedetto, Alexandre; Aschner, Michael R01ES010563 Neurotoxicology (2008 Jul) 18565586 Exiting the NIEHS site 2008 
Manganese Transport into the Brain: Putative Mechanisms.   Aschner, Michael; Dos Santos, Ana Paula Marreilha; Erikson, Keith M; Zheng, Wei R01ES007331, R01ES010563 Met Ions Biol Med (2008 May) 30595649 Exiting the NIEHS site 2008 
Measuring brain manganese and iron accumulation in rats following 14 weeks of low-dose manganese tre ...   Fitsanakis, Vanessa A; Zhang, Na; Anderson, Joel G; Erikson, Keith M; Avison, Malcolm J; Gore, ... R01ES007331, R01ES010563 Toxicol Sci (2008 May) 18234737 Exiting the NIEHS site 2008 
Metallothionein in the central nervous system: Roles in protection, regeneration and cognition.   West, Adrian K; Hidalgo, Juan; Eddins, Donnie; Levin, Edward D; Aschner, Michael P42ES010356, R01ES007331, R01ES010563 Neurotoxicology (2008 May) 18313142 Exiting the NIEHS site 2008 
Mitochondrial-dependent manganese neurotoxicity in rat primary astrocyte cultures.   Yin, Zhaoobao; Aschner, Judy L; dos Santos, Ana Paula; Aschner, Michael R01ES010563 Brain Res (2008 Apr 8) 18313649 Exiting the NIEHS site 2008 
Effects of manganese on thyroid hormone homeostasis: potential links.   Soldin, O P; Aschner, M R01ES010563 Neurotoxicology (2007 Sep) 17576015 Exiting the NIEHS site 2007 
Manganese induces oxidative impairment in cultured rat astrocytes.   Milatovic, Dejan; Yin, Zhaobao; Gupta, Ramesh C; Sidoryk, Marta; Albrecht, Jan; Aschner, Judy ... R01ES010563 Toxicol Sci (2007 Jul) 17468184 Exiting the NIEHS site 2007 
Manganese neurotoxicity: a focus on the neonate.   Erikson, Keith M; Thompson, Khristy; Aschner, Judy; Aschner, Michael R01ES010563 Pharmacol Ther (2007 Feb) 17084903 Exiting the NIEHS site 2007 
Manganese: recent advances in understanding its transport and neurotoxicity.   Aschner, Michael; Guilarte, Tomás R; Schneider, Jay S; Zheng, Wei R01ES010563 Toxicol Appl Pharmacol (2007 Jun 1) 17466353 Exiting the NIEHS site 2007 
Modulation of cholinergic systems by manganese.   Finkelstein, Yoram; Milatovic, Dejan; Aschner, Michael R01ES010563 Neurotoxicology (2007 Sep) 17920128 Exiting the NIEHS site 2007 
Putative proteins involved in manganese transport across the blood-brain barrier.   Fitsanakis, Vanessa A; Piccola, Greg; Marreilha dos Santos, Ana Paula; Aschner, Judy L; Aschner, ... R01ES010563 Hum Exp Toxicol (2007 Apr) 17615110 Exiting the NIEHS site 2007 
Role of glutathione in determining the differential sensitivity between the cortical and cerebellar ...   Kaur, Parvinder; Aschner, Michael; Syversen, Tore R01ES010563 Toxicology (2007 Feb 12) 17169475 Exiting the NIEHS site 2007 
Characteristics of manganese (Mn) transport in rat brain endothelial (RBE4) cells, an in vitro model ...   Fitsanakis, Vanessa A; Piccola, Greg; Aschner, Judy L; Aschner, Michael R01ES010563 Neurotoxicology (2006 Jan) 16169084 Exiting the NIEHS site 2006 
Increased manganese uptake by primary astrocyte cultures with altered iron status is mediated primar ...   Erikson, Keith M; Aschner, Michael R01ES010563 Neurotoxicology (2006 Jan) 16140386 Exiting the NIEHS site 2006 
Manganese transport by rat brain endothelial (RBE4) cell-based transwell model in the presence of as ...   Fitsanakis, Vanessa A; Piccola, Greg; Aschner, Judy L; Aschner, Michael R01ES010563 J Neurosci Res (2005 Jul 15) 15948148 Exiting the NIEHS site 2005 
Nutritional aspects of manganese homeostasis.   Aschner, Judy L; Aschner, Michael R01ES010563 Mol Aspects Med (2005 Aug-Oct) 16099026 Exiting the NIEHS site 2005 
The in vitro uptake of glutamate in GLAST and GLT-1 transfected mutant CHO-K1 cells is inhibited by ...   Mutkus, Lysette; Aschner, Judy L; Fitsanakis, Vanessa; Aschner, Michael R01ES010563 Biol Trace Elem Res (2005 Dec) 16286678 Exiting the NIEHS site 2005 
The role of MT in neurological disorders.   Aschner, Michael; West, Adrian K R01ES007331, R01ES010563 J Alzheimers Dis (2005 Nov) 16308482 Exiting the NIEHS site 2005 
Developmental neuropathology of environmental agents.   Costa, Lucio G; Aschner, Michael; Vitalone, Annabella; Syversen, Tore; Soldin, Offie Porat P30ES007033, R01ES007331, R01ES010563 Annu Rev Pharmacol Toxicol (2004) 14744240 Exiting the NIEHS site 2004 
Manganese exposure and induced oxidative stress in the rat brain.   Erikson, Keith M; Dobson, Allison W; Dorman, David C; Aschner, Michael R01ES007331, R01ES010563 Sci Total Environ (2004 Dec 01) 15504526 Exiting the NIEHS site 2004 
Manganese-induced cytotoxicity in dopamine-producing cells.   Stredrick, Denise L; Stokes, Alan H; Worst, Travis J; Freeman, Willard M; Johnson, Elizabeth A; ... R01ES010563 Neurotoxicology (2004 Jun) 15183009 Exiting the NIEHS site 2004 
Neurotoxicology: principles and considerations of in vitro assessment.   Aschner, Michael; Syversen, Tore R01ES007331, R01ES010563 Altern Lab Anim (2004 Oct) 15651915 Exiting the NIEHS site 2004 
Brain barrier systems: a new frontier in metal neurotoxicological research.   Zheng, Wei; Aschner, Michael; Ghersi-Egea, Jean-Francois P30ES009089, R01ES007331, R01ES010563 Toxicol Appl Pharmacol (2003 Oct 01) 14554098 Exiting the NIEHS site 2003 
Developmental aspects of blood-brain barrier (BBB) and rat brain endothelial (RBE4) cells as in vitr ...   Yang, Jian; Aschner, Michael R01ES007331, R01ES010563 Neurotoxicology (2003 Aug) 12900088 Exiting the NIEHS site 2003 
The Neuron-Glia Unit in Neuropathology: Is it a Double-Edged Sword?   Aschner, Michael; Aschner, Yael; Sonnewald, Ursula R01ES007331, R01ES010563 No Junkan Taisha (2003) 31190696 Exiting the NIEHS site 2003 
Effects of manganese (Mn) on the developing rat brain: oxidative-stress related endpoints.   Weber, Sarah; Dorman, David C; Lash, Lawrence H; Erikson, Keith; Vrana, Kent E; Aschner, Micha ... R01ES007331, R01ES010563 Neurotoxicology (2002 Jul) 12224758 Exiting the NIEHS site 2002 
Effects of manganese on oxidative stress in CATH.a cells.   Worley, Cynthia G; Bombick, David; Allen, Jeffrey W; Suber, R Lee; Aschner, Michael R01ES007331, R01ES010563 Neurotoxicology (2002 Jul) 12224756 Exiting the NIEHS site 2002 
The uptake of manganese in brain endothelial cultures.   Aschner, Michael; Shanker, Gouri; Erikson, Keith; Yang, Jian; Mutkus, Lysette A R01ES007331, R01ES010563 Neurotoxicology (2002 Jul) 12224757 Exiting the NIEHS site 2002 
Transendothelial permeability of chlorpyrifos in RBE4 monolayers is modulated by astrocyte-condition ...   Yang, J; Mutkus, L A; Sumner, D; Stevens, J T; Eldridge, J C; Strandhoy, J W; Aschner, M R01ES007331, R01ES010563 Brain Res Mol Brain Res (2001 Dec 16) 11744161 Exiting the NIEHS site 2001 
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