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Who We Fund: Publication Detail

Project Title: CROSS-TALKING EVENTS OF EUKARYOTIC DDR
PI: Zhu, Qianzheng
Institution: Ohio State University
Grant Number: R01ES012991

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 50 publications
Export to Excel (http://www.niehs.nih.gov//portfolio/index.cfm/portfolio/grantpubdetail/grant_number/R01ES012991/format/excel)
Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Spironolactone-induced XPB degradation requires TFIIH integrity and ubiquitin-selective segregase VC ...   Chauhan, Anil K; Li, Ping; Sun, Yingming; Wani, Gulzar; Zhu, Qianzheng; Wani, Altaf A R01ES012991 Cell Cycle (2021 Jan) 33381997 Exiting the NIEHS site 2021 
USP7-mediated deubiquitination differentially regulates CSB but not UVSSA upon UV radiation-induced ...   Zhu, Qianzheng; Ding, Nan; Wei, Shengcai; Li, Ping; Wani, Gulzar; He, Jinshan; Wani, Altaf A R01ES012991 Cell Cycle (2020 01) 31775559 Exiting the NIEHS site 2020 
Disulfiram combats cancer via crippling valosin-containing protein/p97 segregase adaptor NPL4.   Ding, Nan; Zhu, Qianzheng R01ES012991 Transl Cancer Res (2018 Apr) 30112292 Exiting the NIEHS site 2018 
Copper-mediated DNA damage by the neurotransmitter dopamine and L-DOPA: A pro-oxidant mechanism.   Rehmani, Nida; Zafar, Atif; Arif, Hussain; Hadi, Sheikh Mumtaz; Wani, Altaf A R01ES012991 Toxicol In Vitro (2017 Apr) 28137434 Exiting the NIEHS site 2017 
Human CRL4DDB2 ubiquitin ligase preferentially regulates post-repair chromatin restoration of H3K56A ...   Zhu, Qianzheng; Wei, Shengcai; Sharma, Nidhi; Wani, Gulzar; He, Jinshan; Wani, Altaf A R01ES012991 Oncotarget (2017 Nov 28) 29262658 Exiting the NIEHS site 2017 
Nucleotide Excision Repair: Finely Tuned Molecular Orchestra of Early Pre-incision Events.   Zhu, Qianzheng; Wani, Altaf A R01ES012991 Photochem Photobiol (2017 01) 27696486 Exiting the NIEHS site 2017 
UV radiation-induced SUMOylation of DDB2 regulates nucleotide excision repair.   Han, Chunhua; Zhao, Ran; Kroger, John; He, Jinshan; Wani, Gulzar; Wang, Qi-En; Wani, Altaf A R01ES012991 Carcinogenesis (2017 10 01) 28981631 Exiting the NIEHS site 2017 
UV-induced proteolysis of RNA polymerase II is mediated by VCP/p97 segregase and timely orchestratio ...   He, Jinshan; Zhu, Qianzheng; Wani, Gulzar; Wani, Altaf A R01ES012991 Oncotarget (2017 Feb 14) 28036256 Exiting the NIEHS site 2017 
ATR- and ATM-Mediated DNA Damage Response Is Dependent on Excision Repair Assembly during G1 but Not ...   Ray, Alo; Blevins, Chessica; Wani, Gulzar; Wani, Altaf A R01ES012991 PLoS One (2016) 27442013 Exiting the NIEHS site 2016 
Differential DNA lesion formation and repair in heterochromatin and euchromatin.   Han, Chunhua; Srivastava, Amit Kumar; Cui, Tiantian; Wang, Qi-En; Wani, Altaf A R01ES012991 Carcinogenesis (2016 Feb) 26717995 Exiting the NIEHS site 2016 
Valosin-containing Protein (VCP)/p97 Segregase Mediates Proteolytic Processing of Cockayne Syndrome ...   He, Jinshan; Zhu, Qianzheng; Wani, Gulzar; Sharma, Nidhi; Wani, Altaf A R01ES012991 J Biol Chem (2016 Apr 01) 26826127 Exiting the NIEHS site 2016 
Cdt2-mediated XPG degradation promotes gap-filling DNA synthesis in nucleotide excision repair.   Han, Chunhua; Wani, Gulzar; Zhao, Ran; Qian, Jiang; Sharma, Nidhi; He, Jinshan; Zhu, Qianzhen ... R01ES012991 Cell Cycle (2015) 25483071 Exiting the NIEHS site 2015 
Damaged DNA-binding protein down-regulates epigenetic mark H3K56Ac through histone deacetylase 1 and ...   Zhu, Qianzheng; Battu, Aruna; Ray, Alo; Wani, Gulzar; Qian, Jiang; He, Jinshan; Wang, Qi-en; ... R01ES012991 Mutat Res (2015 Jun) 26255936 Exiting the NIEHS site 2015 
USP7 deubiquitinase promotes ubiquitin-dependent DNA damage signaling by stabilizing RNF168.   Zhu, Qianzheng; Sharma, Nidhi; He, Jinshan; Wani, Gulzar; Wani, Altaf A R01ES012991 Cell Cycle (2015) 25894431 Exiting the NIEHS site 2015 
USP7 modulates UV-induced PCNA monoubiquitination by regulating DNA polymerase eta stability.   Qian, J; Pentz, K; Zhu, Q; Wang, Q; He, J; Srivastava, A K; Wani, A A R01ES012991 Oncogene (2015 Sep 03) 25435364 Exiting the NIEHS site 2015 
DNA damage-binding complex recruits HDAC1 to repress Bcl-2 transcription in human ovarian cancer cel ...   Zhao, Ran; Han, Chunhua; Eisenhauer, Eric; Kroger, John; Zhao, Weiqiang; Yu, Jianhua; Selvendi ... R01ES012991 Mol Cancer Res (2014 Mar) 24249678 Exiting the NIEHS site 2014 
Ubiquitin-specific protease 7 regulates nucleotide excision repair through deubiquitinating XPC prot ...   He, Jinshan; Zhu, Qianzheng; Wani, Gulzar; Sharma, Nidhi; Han, Chunhua; Qian, Jiang; Pentz, K ... R01ES012991 J Biol Chem (2014 Sep 26) 25118285 Exiting the NIEHS site 2014 
USP3 counteracts RNF168 via deubiquitinating H2A and γH2AX at lysine 13 and 15.   Sharma, Nidhi; Zhu, Qianzheng; Wani, Gulzar; He, Jingshan; Wang, Qi-en; Wani, Altaf A R01ES012991 Cell Cycle (2014) 24196443 Exiting the NIEHS site 2014 
Caspase-2 short isoform interacts with membrane-associated cytoskeleton proteins to inhibit apoptosi ...   Han, Chunhua; Zhao, Ran; Kroger, John; Qu, Meihua; Wani, Altaf A; Wang, Qi-En R01ES012991 PLoS One (2013) 23840868 Exiting the NIEHS site 2013 
NER initiation factors, DDB2 and XPC, regulate UV radiation response by recruiting ATR and ATM kinas ...   Ray, Alo; Milum, Keisha; Battu, Aruna; Wani, Gulzar; Wani, Altaf A R01ES012991 DNA Repair (Amst) (2013 Apr 01) 23422745 Exiting the NIEHS site 2013 
p38 MAPK- and Akt-mediated p300 phosphorylation regulates its degradation to facilitate nucleotide e ...   Wang, Qi-En; Han, Chunhua; Zhao, Ran; Wani, Gulzar; Zhu, Qianzheng; Gong, Li; Battu, Aruna; R ... R01ES012991 Nucleic Acids Res (2013 Feb 01) 23275565 Exiting the NIEHS site 2013 
Thymoquinone inhibits autophagy and induces cathepsin-mediated, caspase-independent cell death in gl ...   Racoma, Ira O; Meisen, Walter Hans; Wang, Qi-En; Kaur, Balveen; Wani, Altaf A R01ES012991 PLoS One (2013) 24039814 Exiting the NIEHS site 2013 
Lack of CAK complex accumulation at DNA damage sites in XP-B and XP-B/CS fibroblasts reveals differe ...   Zhu, Qianzheng; Wani, Gulzar; Sharma, Nidhi; Wani, Altaf R01ES012991 DNA Repair (Amst) (2012 Dec 1) 23083890 Exiting the NIEHS site 2012 
Nucleotide excision repair factor XPC enhances DNA damage-induced apoptosis by downregulating the an ...   Wang, Qi-En; Han, Chunhua; Zhang, Bo; Sabapathy, Kanaga; Wani, Altaf A R01ES012991 Cancer Res (2012 Feb 01) 22174370 Exiting the NIEHS site 2012 
ASF1A and ATM regulate H3K56-mediated cell-cycle checkpoint recovery in response to UV irradiation.   Battu, Aruna; Ray, Alo; Wani, Altaf A R01ES012991 Nucleic Acids Res (2011 Oct) 21727091 Exiting the NIEHS site 2011 
Differential contributory roles of nucleotide excision and homologous recombination repair for enhan ...   Wang, Qi-En; Milum, Keisha; Han, Chunhua; Huang, Yi-Wen; Wani, Gulzar; Thomale, Jurgen; Wani, ... R01ES012991 Mol Cancer (2011) 21385444 Exiting the NIEHS site 2011 
Stem cell protein Piwil2 modulates chromatin modifications upon cisplatin treatment.   Wang, Qi-En; Han, Chunhua; Milum, Keisha; Wani, Altaf A R01ES012991 Mutat Res (2011 Mar 15) 21310163 Exiting the NIEHS site 2011 
Thymoquinone up-regulates PTEN expression and induces apoptosis in doxorubicin-resistant human breas ...   Arafa, El-Shaimaa A; Zhu, Qianzheng; Shah, Zubair I; Wani, Gulzar; Barakat, Bassant M; Racoma, ... R01ES012991 Mutat Res (2011 Jan 10) 21040738 Exiting the NIEHS site 2011 
Dissociation of CAK from core TFIIH reveals a functional link between XP-G/CS and the TFIIH disassem ...   Arab, Hany H; Wani, Gulzar; Ray, Alo; Shah, Zubair I; Zhu, Qianzheng; Wani, Altaf A R01ES012991 PLoS One (2010) 20543986 Exiting the NIEHS site 2010 
Histone modifications: crucial elements for damage response and chromatin restoration.   Zhu, Qianzheng; Wani, Altaf A R01ES012991 J Cell Physiol (2010 May) 20112283 Exiting the NIEHS site 2010 
Hsp27 protects adenocarcinoma cells from UV-induced apoptosis by Akt and p21-dependent pathways of s ...   Kanagasabai, Ragu; Karthikeyan, Krishnamurthy; Vedam, Kaushik; Qien, Wang; Zhu, Qianzheng; Ilan ... R01ES012991 Mol Cancer Res (2010 Oct) 20858736 Exiting the NIEHS site 2010 
Overexpression of DDB2 enhances the sensitivity of human ovarian cancer cells to cisplatin by augmen ...   Barakat, Bassant M; Wang, Qi-En; Han, Chunhua; Milum, Keisha; Yin, De-Tao; Zhao, Qun; Wani, G ... R01ES012991 Int J Cancer (2010 Aug 15) 20013802 Exiting the NIEHS site 2010 
Chromatin restoration following nucleotide excision repair involves the incorporation of ubiquitinat ...   Zhu, Qianzheng; Wani, Gulzar; Arab, Hany H; El-Mahdy, Mohamed A; Ray, Alo; Wani, Altaf A R01ES012991 DNA Repair (Amst) (2009 Feb 01) 19059499 Exiting the NIEHS site 2009 
Human SNF5/INI1, a component of the human SWI/SNF chromatin remodeling complex, promotes nucleotide ...   Ray, Alo; Mir, Safita N; Wani, Gulzar; Zhao, Qun; Battu, Aruna; Zhu, Qianzheng; Wang, Qi-En; ... R01ES012991 Mol Cell Biol (2009 Dec) 19805520 Exiting the NIEHS site 2009 
Modulation of nucleotide excision repair by mammalian SWI/SNF chromatin-remodeling complex.   Zhao, Qun; Wang, Qi-En; Ray, Alo; Wani, Gulzar; Han, Chunhua; Milum, Keisha; Wani, Altaf A R01ES012991 J Biol Chem (2009 Oct 30) 19740755 Exiting the NIEHS site 2009 
Sem1p and Ubp6p orchestrate telomeric silencing by modulating histone H2B ubiquitination and H3 acet ...   Qin, Song; Wang, Qien; Ray, Alo; Wani, Gulzar; Zhao, Qun; Bhaumik, Sukesh R; Wani, Altaf A R01ES012991 Nucleic Acids Res (2009 Apr) 19188254 Exiting the NIEHS site 2009 
Tangeretin sensitizes cisplatin-resistant human ovarian cancer cells through downregulation of phosp ...   Arafa, El-Shaimaa A; Zhu, Qianzheng; Barakat, Bassant M; Wani, Gulzar; Zhao, Qun; El-Mahdy, Mo ... R01ES012991 Cancer Res (2009 Dec 01) 19903849 Exiting the NIEHS site 2009 
Naringenin protects HaCaT human keratinocytes against UVB-induced apoptosis and enhances the removal ...   El-Mahdy, Mohamed A; Zhu, Qianzheng; Wang, Qi-En; Wani, Gulzar; Patnaik, Srinivas; Zhao, Qun; ... R01ES012991 Photochem Photobiol (2008 Mar-Apr) 18086244 Exiting the NIEHS site 2008 
The p38 mitogen-activated protein kinase augments nucleotide excision repair by mediating DDB2 degra ...   Zhao, Qun; Barakat, Bassant M; Qin, Song; Ray, Alo; El-Mahdy, Mohamed A; Wani, Gulzar; Arafa, ... R01ES012991 J Biol Chem (2008 Nov 21) 18806262 Exiting the NIEHS site 2008 
Role of Claspin in regulation of nucleotide excision repair factor DDB2.   Praetorius-Ibba, Mette; Wang, Qi-En; Wani, Gulzar; El-Mahdy, Mohamed A; Zhu, Qianzheng; Qin, S ... R01ES012991 DNA Repair (Amst) (2007 May 01) 17196446 Exiting the NIEHS site 2007 
The ubiquitin-proteasome system regulates p53-mediated transcription at p21waf1 promoter.   Zhu, Q; Wani, G; Yao, J; Patnaik, S; Wang, Q-E; El-Mahdy, M A; Praetorius-Ibba, M; Wani, A A R01ES012991 Oncogene (2007 Jun 21) 17224908 Exiting the NIEHS site 2007 
Ubiquitylation-independent degradation of Xeroderma pigmentosum group C protein is required for effi ...   Wang, Qi-En; Praetorius-Ibba, Mette; Zhu, Qianzheng; El-Mahdy, Mohamed A; Wani, Gulzar; Zhao, ... R01ES012991 Nucleic Acids Res (2007) 17693435 Exiting the NIEHS site 2007 
Cullin 4A-mediated proteolysis of DDB2 protein at DNA damage sites regulates in vivo lesion recognit ...   El-Mahdy, Mohamed A; Zhu, Qianzheng; Wang, Qi-en; Wani, Gulzar; Praetorius-Ibba, Mette; Wani, ... R01ES012991 J Biol Chem (2006 May 12) 16527807 Exiting the NIEHS site 2006 
DNA damage binding protein component DDB1 participates in nucleotide excision repair through DDB2 DN ...   Li, Jinyou; Wang, Qi-En; Zhu, Qianzheng; El-Mahdy, Mohamed A; Wani, Gulzar; Praetorius-Ibba, M ... R01ES012991 Cancer Res (2006 Sep 01) 16951172 Exiting the NIEHS site 2006 
Cellular ubiquitination and proteasomal functions positively modulate mammalian nucleotide excision ...   Wang, Qi-En; Wani, Manzoor A; Chen, Jianming; Zhu, Qianzheng; Wani, Gulzar; El-Mahdy, Mohamed ... R01ES012991 Mol Carcinog (2005 Jan) 15547920 Exiting the NIEHS site 2005 
Deubiquitination by proteasome is coordinated with substrate translocation for proteolysis in vivo.   Zhu, Qianzheng; Wani, Gulzar; Wang, Qi-en; El-mahdy, Mohamed; Snapka, Robert M; Wani, Altaf A R01ES012991 Exp Cell Res (2005 Jul 15) 15950624 Exiting the NIEHS site 2005 
DNA repair factor XPC is modified by SUMO-1 and ubiquitin following UV irradiation.   Wang, Qi-En; Zhu, Qianzheng; Wani, Gulzar; El-Mahdy, Mohamed A; Li, Jinyou; Wani, Altaf A R01ES012991 Nucleic Acids Res (2005) 16030353 Exiting the NIEHS site 2005 
Thymoquinone induces apoptosis through activation of caspase-8 and mitochondrial events in p53-null ...   El-Mahdy, Mohamed A; Zhu, Qianzheng; Wang, Qi-En; Wani, Gulzar; Wani, Altaf A R01ES012991 Int J Cancer (2005 Nov 10) 15906362 Exiting the NIEHS site 2005 
UV radiation-induced XPC translocation within chromatin is mediated by damaged-DNA binding protein, ...   Wang, Qi-En; Zhu, Qianzheng; Wani, Gulzar; Chen, Jianming; Wani, Altaf A R01ES012991 Carcinogenesis (2004 Jun) 14742321 Exiting the NIEHS site 2004 
Genetic control of interconnected neuronal populations in the mouse primary visual system.   Seecharan, Dave J; Kulkarni, Anand L; Lu, Lu; Rosen, Glenn D; Williams, Robert W R01ES012991 J Neurosci (2003 Dec 03) 14657177 Exiting the NIEHS site 2003 
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