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Who We Fund: Publication Detail

Project Title: TRANSLESION SYNTHESIS DNA POLYMERASES AND GENOME INSTABILITY
PI: Shcherbakova, Polina V
Institution: University Of Nebraska Medical Center
Grant Number: R01ES015869

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 21 publications
Export to Excel (http://www.niehs.nih.gov//portfolio/index.cfm/portfolio/grantpubdetail/grant_number/R01ES015869/format/excel)
Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
DNA polymerase δ proofreads errors made by DNA polymerase ε.   Bulock, Chelsea R; Xing, Xuanxuan; Shcherbakova, Polina V R01ES015869 Proc Natl Acad Sci U S A (2020 03 17) 32123096 Exiting the NIEHS site 2020 
Homologous Recombination Repair Truncations Predict Hypermutation in Microsatellite Stable Colorecta ...   Lee, Minyi; Eng, George; Barbari, Stephanie R; Deshpande, Vikram; Shcherbakova, Polina V; Gala, ... R01ES015869 Clin Transl Gastroenterol (2020 03) 32352724 Exiting the NIEHS site 2020 
Mismatch repair and DNA polymerase δ proofreading prevent catastrophic accumulation of leading stran ...   Bulock, Chelsea R; Xing, Xuanxuan; Shcherbakova, Polina V R01ES015869 Nucleic Acids Res (2020 09 18) 32756902 Exiting the NIEHS site 2020 
A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme.   Xing, Xuanxuan; Kane, Daniel P; Bulock, Chelsea R; Moore, Elizabeth A; Sharma, Sushma; Chabes, ... R01ES015869 Nat Commun (2019 01 22) 30670691 Exiting the NIEHS site 2019 
Structural consequence of the most frequently recurring cancer-associated substitution in DNA polyme ...   Parkash, Vimal; Kulkarni, Yashraj; Ter Beek, Josy; Shcherbakova, Polina V; Kamerlin, Shina Caro ... R01ES015869 Nat Commun (2019 01 22) 30670696 Exiting the NIEHS site 2019 
Functional Analysis of Cancer-Associated DNA Polymerase ε Variants in Saccharomyces cerevisiae.   Barbari, Stephanie R; Kane, Daniel P; Moore, Elizabeth A; Shcherbakova, Polina V R01ES015869 G3 (Bethesda) (2018 03 02) 29352080 Exiting the NIEHS site 2018 
Nucleotide selectivity defect and mutator phenotype conferred by a colon cancer-associated DNA polym ...   Mertz, T M; Baranovskiy, A G; Wang, J; Tahirov, T H; Shcherbakova, P V R01ES015869 Oncogene (2017 Aug) 28368425 Exiting the NIEHS site 2017 
Replicative DNA polymerase defects in human cancers: Consequences, mechanisms, and implications for ...   Barbari, Stephanie R; Shcherbakova, Polina V R01ES015869 DNA Repair (Amst) (2017 08) 28687338 Exiting the NIEHS site 2017 
Yeast DNA polymerase ζ maintains consistent activity and mutagenicity across a wide range of physiol ...   Kochenova, Olga V; Bezalel-Buch, Rachel; Tran, Phong; Makarova, Alena V; Chabes, Andrei; Burger ... R01ES015869 Nucleic Acids Res (2017 02 17) 28180291 Exiting the NIEHS site 2017 
Yeast DNA polymerase ζ maintains consistent activity and mutagenicity across a wide range of physiol ...   Kochenova, Olga V; Bezalel-Buch, Rachel; Tran, Phong; Makarova, Alena V; Chabes, Andrei; Burger ... R01ES015869 Nucleic Acids Res (2016 Nov 29) 27903904 Exiting the NIEHS site 2016 
Colon cancer-associated mutator DNA polymerase δ variant causes expansion of dNTP pools increasing i ...   Mertz, Tony M; Sharma, Sushma; Chabes, Andrei; Shcherbakova, Polina V R01ES015869 Proc Natl Acad Sci U S A (2015 May 12) 25827231 Exiting the NIEHS site 2015 
DNA polymerase ζ-dependent lesion bypass in Saccharomyces cerevisiae is accompanied by error-prone c ...   Kochenova, Olga V; Daee, Danielle L; Mertz, Tony M; Shcherbakova, Polina V R01ES015869 PLoS Genet (2015 Mar) 25826305 Exiting the NIEHS site 2015 
A common cancer-associated DNA polymerase ε mutation causes an exceptionally strong mutator phenotyp ...   Kane, Daniel P; Shcherbakova, Polina V R01ES015869 Cancer Res (2014 Apr 1) 24525744 Exiting the NIEHS site 2014 
DNA polymerases ζ and Rev1 mediate error-prone bypass of non-B DNA structures.   Northam, Matthew R; Moore, Elizabeth A; Mertz, Tony M; Binz, Sara K; Stith, Carrie M; Stepchenk ... R01ES015869 Nucleic Acids Res (2014 Jan) 24049079 Exiting the NIEHS site 2014 
A reversible histone H3 acetylation cooperates with mismatch repair and replicative polymerases in m ...   Kadyrova, Lyudmila Y; Mertz, Tony M; Zhang, Yu; Northam, Matthew R; Sheng, Ziwei; Lobachev, Ki ... R01ES015869 PLoS Genet (2013 Oct) 24204308 Exiting the NIEHS site 2013 
Role of DNA polymerases in repeat-mediated genome instability.   Shah, Kartik A; Shishkin, Alexander A; Voineagu, Irina; Pavlov, Youri I; Shcherbakova, Polina V ... R01ES015869 Cell Rep (2012 Nov 29) 23142667 Exiting the NIEHS site 2012 
Participation of translesion synthesis DNA polymerases in the maintenance of chromosome integrity in ...   Kochenova, O V; Soshkina, J V; Stepchenkova, E I; Inge-Vechtomov, S G; Shcherbakova, P V R01ES015869 Biochemistry (Mosc) (2011 Jan) 21568839 Exiting the NIEHS site 2011 
The non-canonical protein binding site at the monomer-monomer interface of yeast proliferating cell ...   Sharma, Neeru M; Kochenova, Olga V; Shcherbakova, Polina V R01ES015869 J Biol Chem (2011 Sep 23) 21799021 Exiting the NIEHS site 2011 
A cancer-associated DNA polymerase delta variant modeled in yeast causes a catastrophic increase in ...   Daee, Danielle L; Mertz, Tony M; Shcherbakova, Polina V R01ES015869 Proc Natl Acad Sci U S A (2010 Jan 5) 19966286 Exiting the NIEHS site 2010 
DNA polymerases at the eukaryotic fork-20 years later.   Pavlov, Youri I; Shcherbakova, Polina V R01ES015869 Mutat Res (2010 Mar 01) 19682465 Exiting the NIEHS site 2010 
Participation of DNA polymerase zeta in replication of undamaged DNA in Saccharomyces cerevisiae.   Northam, Matthew R; Robinson, Heather A; Kochenova, Olga V; Shcherbakova, Polina V R01ES015869 Genetics (2010 Jan) 19841096 Exiting the NIEHS site 2010 
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