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Your Environment. Your Health.

Who We Fund: Publication Detail

Project Title: LUNG MACROPHAGE METABOLIC REPROGRAMMING IN ASBESTOS-INDUCED TOXICITY
PI: Carter, A Brent
Institution: University Of Alabama At Birmingham
Grant Number: R01ES015981

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 35 publications
Export to Excel (http://www.niehs.nih.gov//portfolio/index.cfm/portfolio/grantpubdetail/grant_number/R01ES015981/format/excel)
Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
C(C)Learing the Role of Chemokines in Pulmonary Fibrosis.   He, Chao; Carter, A Brent R01ES015981 Am J Respir Cell Mol Biol (2020 05) 31951476 Exiting the NIEHS site 2020 
Mitochondrial quality control in pulmonary fibrosis.   Larson-Casey, Jennifer L; He, Chao; Carter, A Brent R01ES015981 Redox Biol (2020 06) 31928788 Exiting the NIEHS site 2020 
Increased flux through the mevalonate pathway mediates fibrotic repair without injury.   Larson-Casey, Jennifer L; Vaid, Mudit; Gu, Linlin; He, Chao; Cai, Guo-Qiang; Ding, Qiang; Davi ... R01ES015981, R01ES029981 J Clin Invest (2019 11 01) 31609245 Exiting the NIEHS site 2019 
Mitochondrial calcium uniporter regulates PGC-1α expression to mediate metabolic reprogramming in pu ...   Gu, Linlin; Larson Casey, Jennifer L; Andrabi, Shaida A; Lee, Jun Hee; Meza-Perez, Selene; Rand ... R01ES015981 Redox Biol (2019 09) 31473487 Exiting the NIEHS site 2019 
NOX4 modulates macrophage phenotype and mitochondrial biogenesis in asbestosis.   He, Chao; Larson-Casey, Jennifer L; Davis, Dana; Hanumanthu, Vidya Sagar; Longhini, Ana Leda F; ... R01ES015981 JCI Insight (2019 08 22) 31434799 Exiting the NIEHS site 2019 
Reply to Eapen et al.: Dysfunctional Immunity and Microbial Adhesion Molecules in Smoking-induced Pn ...   Larson-Casey, Jennifer L; Carter, A Brent R01ES015981 Am J Respir Crit Care Med (2019 01 15) 30290120 Exiting the NIEHS site 2019 
Macrophage Rac2 Is Required to Reduce the Severity of Cigarette Smoke-induced Pneumonia.   Larson-Casey, Jennifer L; Gu, Linlin; Jackson, Patricia L; Briles, David E; Hale, Joanetha Y; B ... R01ES015981, R01ES029981 Am J Respir Crit Care Med (2018 11 15) 29897791 Exiting the NIEHS site 2018 
Macrophages utilize the mitochondrial calcium uniporter for profibrotic polarization.   Gu, Linlin; Larson-Casey, Jennifer L; Carter, A Brent R01ES015981 FASEB J (2017 07) 28351840 Exiting the NIEHS site 2017 
NADPH Oxidase 4 (Nox4) Suppresses Mitochondrial Biogenesis and Bioenergetics in Lung Fibroblasts via ...   Bernard, Karen; Logsdon, Naomi J; Miguel, Veronica; Benavides, Gloria A; Zhang, Jianhua; Carter ... R01ES015981 J Biol Chem (2017 02 17) 28049732 Exiting the NIEHS site 2017 
Serpine 1 induces alveolar type II cell senescence through activating p53-p21-Rb pathway in fibrotic ...   Jiang, Chunsun; Liu, Gang; Luckhardt, Tracy; Antony, Veena; Zhou, Yong; Carter, A Brent; Thann ... R01ES015981 Aging Cell (2017 10) 28722352 Exiting the NIEHS site 2017 
Assay to evaluate BAL Fluid regulation of Fibroblast α-SMA Expression.   Larson-Casey, Jennifer L; Carter, A Brent R01ES015981 Bio Protoc (2016 Nov 20) 28239621 Exiting the NIEHS site 2016 
CaMKII inhibition in type II pneumocytes protects from bleomycin-induced pulmonary fibrosis by preve ...   Winters, Christopher J; Koval, Olha; Murthy, Shubha; Allamargot, Chantal; Sebag, Sara C; Paschk ... R01ES015981 Am J Physiol Lung Cell Mol Physiol (2016 Jan 01) 26545899 Exiting the NIEHS site 2016 
Cu,Zn-Superoxide Dismutase-Mediated Redox Regulation of Jumonji Domain Containing 3 Modulates Macrop ...   He, Chao; Larson-Casey, Jennifer L; Gu, Linlin; Ryan, Alan J; Murthy, Shubha; Carter, A Brent R01ES015981 Am J Respir Cell Mol Biol (2016 07) 26699812 Exiting the NIEHS site 2016 
Determination of H2O2 Generation by pHPA Assay.   Larson-Casey, Jennifer L; Carter, A Brent R01ES015981 Bio Protoc (2016 Nov 20) 28280752 Exiting the NIEHS site 2016 
Macrophage Akt1 Kinase-Mediated Mitophagy Modulates Apoptosis Resistance and Pulmonary Fibrosis.   Larson-Casey, Jennifer L; Deshane, Jessy S; Ryan, Alan J; Thannickal, Victor J; Carter, A Brent R01ES015981 Immunity (2016 Mar 15) 26921108 Exiting the NIEHS site 2016 
Alternative activation of macrophages and pulmonary fibrosis are modulated by scavenger receptor, ma ...   Murthy, Shubha; Larson-Casey, Jennifer L; Ryan, Alan J; He, Chao; Kobzik, Lester; Carter, A Br ... R01ES015981 FASEB J (2015 Aug) 25953850 Exiting the NIEHS site 2015 
Heme oxygenase-1-mediated autophagy protects against pulmonary endothelial cell death and developmen ...   Surolia, Ranu; Karki, Suman; Kim, Hyunki; Yu, Zhihong; Kulkarni, Tejaswini; Mirov, Sergey B; C ... R01ES015981, U01ES026458 Am J Physiol Lung Cell Mol Physiol (2015 Aug 01) 26071551 Exiting the NIEHS site 2015 
Mitochondrial-targeted antioxidant therapy decreases transforming growth factor-β-mediated collagen ...   Jaffer, Omar A; Carter, A Brent; Sanders, Philip N; Dibbern, Megan E; Winters, Christopher J; M ... P30ES005605, R01ES015981 Am J Respir Cell Mol Biol (2015 Jan) 24988374 Exiting the NIEHS site 2015 
Targeting the isoprenoid pathway to abrogate progression of pulmonary fibrosis.   Osborn-Heaford, Heather L; Murthy, Shubha; Gu, Linlin; Larson-Casey, Jennifer L; Ryan, Alan J; ... R01ES015981 Free Radic Biol Med (2015 Sep) 25958207 Exiting the NIEHS site 2015 
The Metabolic Prospective and Redox Regulation of Macrophage Polarization.   He, Chao; Carter, A Brent R01ES015981 J Clin Cell Immunol (2015 Dec) 26962470 Exiting the NIEHS site 2015 
Acrolein-exposed normal human lung fibroblasts in vitro: cellular senescence, enhanced telomere eros ...   Jang, Jun-Ho; Bruse, Shannon; Huneidi, Salam; Schrader, Ronald M; Monick, Martha M; Lin, Yong; ... R01ES015981 Environ Health Perspect (2014 Sep) 24747221 Exiting the NIEHS site 2014 
Asbestos-induced disruption of calcium homeostasis induces endoplasmic reticulum stress in macrophag ...   Ryan, Alan J; Larson-Casey, Jennifer L; He, Chao; Murthy, Shuhba; Carter, A Brent P30ES005605, R01ES015981 J Biol Chem (2014 Nov 28) 25324550 Exiting the NIEHS site 2014 
Modulation of the mevalonate pathway by akt regulates macrophage survival and development of pulmona ...   Larson-Casey, Jennifer L; Murthy, Shubha; Ryan, Alan J; Carter, A Brent P30ES005605, R01ES015981 J Biol Chem (2014 Dec 26) 25378391 Exiting the NIEHS site 2014 
Accelerated development of pulmonary fibrosis via Cu,Zn-superoxide dismutase-induced alternative act ...   He, Chao; Ryan, Alan J; Murthy, Shubha; Carter, A Brent P30ES005605, R01ES015981 J Biol Chem (2013 Jul 12) 23720777 Exiting the NIEHS site 2013 
Expression of human paraoxonase 1 decreases superoxide levels and alters bacterial colonization in t ...   Pezzulo, Alejandro A; Hornick, Emma E; Rector, Michael V; Estin, Miriam; Reisetter, Anna C; Taf ... R01ES015981 PLoS One (2012) 22952763 Exiting the NIEHS site 2012 
Mitochondrial Rac1 GTPase import and electron transfer from cytochrome c are required for pulmonary ...   Osborn-Heaford, Heather L; Ryan, Alan J; Murthy, Shubha; Racila, Ana-Monica; He, Chao; Sieren, ... R01ES015981 J Biol Chem (2012 Jan 27) 22157762 Exiting the NIEHS site 2012 
SP-1 regulation of MMP-9 expression requires Ser586 in the PEST domain.   Murthy, Shubha; Ryan, Alan J; Carter, A Brent R01ES015981 Biochem J (2012 Jul 15) 22519702 Exiting the NIEHS site 2012 
The multifunctional Ca2+/calmodulin-dependent kinase II regulates vascular smooth muscle migration t ...   Scott, Jason A; Xie, Litao; Li, Hui; Li, Weiwei; He, Julie B; Sanders, Philip N; Carter, A Br ... R01ES015981 Am J Physiol Heart Circ Physiol (2012 May 15) 22427508 Exiting the NIEHS site 2012 
Mitochondrial Cu,Zn-superoxide dismutase mediates pulmonary fibrosis by augmenting H2O2 generation.   He, Chao; Murthy, Shubha; McCormick, Michael L; Spitz, Douglas R; Ryan, Alan J; Carter, A Bren ... R01ES015981 J Biol Chem (2011 Apr 29) 21393238 Exiting the NIEHS site 2011 
Nuclear factor kappa B-dependent gene transcription in cholecystokinin- and tumor necrosis factor-al ...   Williard, Deborah E; Twait, Erik; Yuan, Zuobiao; Carter, A Brent; Samuel, Isaac R01ES015981 Am J Surg (2010 Aug) 20413104 Exiting the NIEHS site 2010 
Rac1-mediated mitochondrial H2O2 generation regulates MMP-9 gene expression in macrophages via inhib ...   Murthy, Shubha; Ryan, Alan; He, Chao; Mallampalli, Rama K; Carter, A Brent R01ES015981 J Biol Chem (2010 Aug 06) 20529870 Exiting the NIEHS site 2010 
Modulation of reactive oxygen species by Rac1 or catalase prevents asbestos-induced pulmonary fibros ...   Murthy, Shubha; Adamcakova-Dodd, Andrea; Perry, Sarah S; Tephly, Linda A; Keller, Richard M; Me ... R01ES015981 Am J Physiol Lung Cell Mol Physiol (2009 Nov) 19684199 Exiting the NIEHS site 2009 
15-deoxy-Delta12,14-prostaglandin J2 impairs phosphatidylcholine synthesis and induces nuclear accum ...   Ryan, Alan J; Chen, Bill B; Vennalaganti, Prashanth R; Henderson, Florita C; Tephly, Linda A; C ... R01ES015981 J Biol Chem (2008 Sep 5) 18614529 Exiting the NIEHS site 2008 
Asbestos-induced MKP-3 expression augments TNF-alpha gene expression in human monocytes.   Tephly, Linda A; Carter, A Brent R01ES015981 Am J Respir Cell Mol Biol (2008 Jul) 18314537 Exiting the NIEHS site 2008 
The Nalp3 inflammasome is essential for the development of silicosis.   Cassel, Suzanne L; Eisenbarth, Stephanie C; Iyer, Shankar S; Sadler, Jeffrey J; Colegio, Oscar ... R01ES015981 Proc Natl Acad Sci U S A (2008 Jul 01) 18577586 Exiting the NIEHS site 2008 
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