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Who We Fund: Publication Detail

Project Title: THE UGT2A AND 3A METABOLIZING ENZYMES AND TOBACCO-RELATED CANCER RISK
PI: Lazarus, Philip
Institution: Washington State University
Grant Number: R01ES025460

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 27 publications
Export to Excel (http://www.niehs.nih.gov//portfolio/index.cfm/portfolio/grantpubdetail/grant_number/R01ES025460/format/excel)
Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Comparison of tobacco-specific nitrosamine levels in smokeless tobacco products: High levels in prod ...   Nasrin, Shamema; Chen, Gang; Watson, Christy J W; Lazarus, Philip R01ES025460 PLoS One (2020) 32453764 Exiting the NIEHS site 2020 
Genetic variants in CYP2A6 and UGT1A9 genes associated with urinary nicotine metabolites in young Me ...   Borrego-Soto, Gissela; Perez-Paramo, Yadira X; Chen, Gang; Santuario-Facio, Sandra K; Santos-Guz ... R01ES025460 Pharmacogenomics J (2020 08) 31959879 Exiting the NIEHS site 2020 
Use of Phenotypically Poor Metabolizer Individual Donor Human Liver Microsomes To Identify Selective ...   Milani, Nicolo; Qiu, NaHong; Molitor, Birgit; Badée, Justine; Cruciani, Gabriele; Fowler, Step ... R01ES025460 Drug Metab Dispos (2020 03) 31839590 Exiting the NIEHS site 2020 
Variation in the UGT2B17 genotype, exemestane metabolism and menopause-related toxicities in the CCT ...   Ho, Vikki; Pasquet, Romain; Luo, Shaman; Chen, Gang; Goss, Paul; Tu, Dongsheng; Lazarus, Phil ... R01ES025460 Breast Cancer Res Treat (2020 Oct) 32715442 Exiting the NIEHS site 2020 
Nicotine-N'-Oxidation by Flavin Monooxygenase Enzymes.   Perez-Paramo, Yadira X; Chen, Gang; Ashmore, Joseph H; Watson, Christy J W; Nasrin, Shamema; Ad ... R01ES025460 Cancer Epidemiol Biomarkers Prev (2019 02) 30381441 Exiting the NIEHS site 2019 
Potential Regulation of UGT2B10 and UGT2B7 by miR-485-5p in Human Liver.   Sutliff, Aimee K; Shi, Jian; Watson, Christy J W; Hunt, Martina S; Chen, Gang; Zhu, Hao-Jie; L ... R01ES025460 Mol Pharmacol (2019 12) 31554697 Exiting the NIEHS site 2019 
Prominent Stereoselectivity of NNAL Glucuronidation in Upper Aerodigestive Tract Tissues.   Kozlovich, Shannon; Chen, Gang; Watson, Christy J W; Lazarus, Philip R01ES025460 Chem Res Toxicol (2019 08 19) 31307193 Exiting the NIEHS site 2019 
Regulation of UGT2A1 by miR-196a-5p and miR-196b-5p.   Sutliff, Aimee K; Watson, Christy J W; Chen, Gang; Lazarus, Philip R01ES025460 J Pharmacol Exp Ther (2019 05) 30850392 Exiting the NIEHS site 2019 
Role of l- and d-Menthol in the Glucuronidation and Detoxification of the Major Lung Carcinogen, NNA ...   Kozlovich, Shannon; Chen, Gang; Watson, Christy J W; Blot, William J; Lazarus, Philip R01ES025460 Drug Metab Dispos (2019 12) 31578206 Exiting the NIEHS site 2019 
Carbonyl reduction of NNK by recombinant human lung enzymes: identification of HSD17β12 as the reduc ...   Ashmore, Joseph H; Luo, Shaman; Watson, Christy J W; Lazarus, Philip R01ES025460 Carcinogenesis (2018 07 30) 29788210 Exiting the NIEHS site 2018 
Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity.   Ferreiro-Iglesias, Aida; Lesseur, Corina; McKay, James; Hung, Rayjean J; Han, Younghun; Zong, ... R01ES025460 Nat Commun (2018 09 25) 30254314 Exiting the NIEHS site 2018 
Identification of the 4-Position of 3-Alkynyl and 3-Heteroaromatic Substituted Pyridine Methanamines ...   Denton, Travis T; Srivastava, Pramod; Xia, Zuping; Chen, Gang; Watson, Christy J W; Wynd, Alec ... R01ES025460 J Med Chem (2018 08 23) 29995408 Exiting the NIEHS site 2018 
Acute and chronic in vivo effects of exposure to nicotine and propylene glycol from an E-cigarette o ...   Laube, Beth L; Afshar-Mohajer, Nima; Koehler, Kirsten; Chen, Gang; Lazarus, Philip; Collaco, J ... R01ES025460 Inhal Toxicol (2017 04) 28651446 Exiting the NIEHS site 2017 
Alcohol and lung cancer risk among never smokers: A pooled analysis from the international lung canc ...   Fehringer, Gordon; Brenner, Darren R; Zhang, Zuo-Feng; Lee, Yuan-Chin Amy; Matsuo, Keitaro; Ito ... R01ES025460 Int J Cancer (2017 05 01) 28120396 Exiting the NIEHS site 2017 
Design, Implementation, and Assessment Approaches Within a Pharmacogenomics Course.   Remsberg, Connie M; Bray, Brenda S; Wright, Susan K; Ashmore, Joe; Kabasenche, William; Wang, ... R01ES025460 Am J Pharm Educ (2017 Feb 25) 28289301 Exiting the NIEHS site 2017 
Association between Glucuronidation Genotypes and Urinary NNAL Metabolic Phenotypes in Smokers.   Chen, Gang; Luo, Shaman; Kozlovich, Shannon; Lazarus, Philip R01ES025460 Cancer Epidemiol Biomarkers Prev (2016 07) 27197298 Exiting the NIEHS site 2016 
Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With Hi ...   Chen, Li-Shiun; Baker, Timothy; Hung, Rayjean J; Horton, Amy; Culverhouse, Robert; Hartz, Sara ... R01ES025460 EBioMedicine (2016 Sep) 27543155 Exiting the NIEHS site 2016 
Low frequency of cigarette smoking and the risk of head and neck cancer in the INHANCE consortium po ...   Berthiller, Julien; Straif, Kurt; Agudo, Antonio; Ahrens, Wolfgang; Bezerra Dos Santos, Alexand ... R01ES025460 Int J Epidemiol (2016 Jun) 26228584 Exiting the NIEHS site 2016 
Mouthwash use and cancer of the head and neck: a pooled analysis from the International Head and Nec ...   Boffetta, Paolo; Hayes, Richard B; Sartori, Samantha; Lee, Yuan-Chin A; Muscat, Joshua; Olshan, ... P30ES010126, R01ES025460 Eur J Cancer Prev (2016 07) 26275006 Exiting the NIEHS site 2016 
Pharmacokinetic analysis and comparison of caffeine administered rapidly or slowly in coffee chilled ...   White Jr, John R; Padowski, Jeannie M; Zhong, Yili; Chen, Gang; Luo, Shaman; Lazarus, Philip; ... R01ES025460 Clin Toxicol (Phila) (2016) 27100333 Exiting the NIEHS site 2016 
Regulation of UGT2B Expression and Activity by miR-216b-5p in Liver Cancer Cell Lines.   Dluzen, Douglas F; Sutliff, Aimee K; Chen, Gang; Watson, Christy J W; Ishmael, Faoud T; Lazarus ... R01ES025460 J Pharmacol Exp Ther (2016 10) 27474751 Exiting the NIEHS site 2016 
Adult Behavior in Male Mice Exposed to E-Cigarette Nicotine Vapors during Late Prenatal and Early Po ...   Smith, Dani; Aherrera, Angela; Lopez, Armando; Neptune, Enid; Winickoff, Jonathan P; Klein, Jo ... R01ES025460 PLoS One (2015) 26372012 Exiting the NIEHS site 2015 
MicroRNA regulation of the major drug-metabolizing enzymes and related transcription factors.   Dluzen, Douglas F; Lazarus, Philip R01ES025460 Drug Metab Rev (2015 08) 26300547 Exiting the NIEHS site 2015 
Milk Thistle Constituents Inhibit Raloxifene Intestinal Glucuronidation: A Potential Clinically Rele ...   Gufford, Brandon T; Chen, Gang; Vergara, Ana G; Lazarus, Philip; Oberlies, Nicholas H; Paine, ... R01ES025460 Drug Metab Dispos (2015 Sep) 26070840 Exiting the NIEHS site 2015 
NNK reduction pathway gene polymorphisms and risk of lung cancer.   Modesto, Jennifer L; Hull, Anna; Angstadt, Andrea Y; Berg, Arthur; Gallagher, Carla J; Lazarus, ... R01ES025460 Mol Carcinog (2015 Jun) 24976539 Exiting the NIEHS site 2015 
Stereospecific Metabolism of the Tobacco-Specific Nitrosamine, NNAL.   Kozlovich, Shannon; Chen, Gang; Lazarus, Philip R01ES025460 Chem Res Toxicol (2015 Nov 16) 26452127 Exiting the NIEHS site 2015 
The effects of electronic cigarette emissions on systemic cotinine levels, weight and postnatal lung ...   McGrath-Morrow, Sharon A; Hayashi, Madoka; Aherrera, Angela; Lopez, Armando; Malinina, Alla; Co ... R01ES025460 PLoS One (2015) 25706869 Exiting the NIEHS site 2015 
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