Skip Navigation

Who We Fund: Publication Detail

Project Title: ENVIRONMENTAL DNA LESIONS AND MUTAGENESIS: MOLECULAR MECHANISMS OF LESION RECOGNITION FOR REPAIR AND POLYMERASE BYPASS
PI: Broyde, Suse
Institution: New York University
Grant Number: R01ES025987

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 26 publications
Export to Excel (http://www.niehs.nih.gov//portfolio/index.cfm?do=portfolio.grantpubdetail&&grant_number=R01ES025987&format=excel)
Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Differing structures and dynamics of two photolesions portray verification differences by the human ...   Fu, Iwen; Geacintov, Nicholas E; Broyde, Suse R01ES025987 Nucleic Acids Res (2023 Dec 11) 37933861 Exiting the NIEHS site 2023 
Inhibition of E. coli RecQ Helicase Activity by Structurally Distinct DNA Lesions: Structure-Functio ...   Sales, Ana H; Zheng, Vincent; Kenawy, Maya A; Kakembo, Mark; Zhang, Lu; Shafirovich, Vladimir; ... R01ES025987 Int J Mol Sci (2022 Dec 09) 36555294 Exiting the NIEHS site 2022 
Mechanism of lesion verification by the human XPD helicase in nucleotide excision repair.   Fu, Iwen; Mu, Hong; Geacintov, Nicholas E; Broyde, Suse R01ES025987 Nucleic Acids Res (2022 Jul 08) 35713557 Exiting the NIEHS site 2022 
Impact of DNA sequences on DNA 'opening' by the Rad4/XPC nucleotide excision repair complex.   Paul, Debamita; Mu, Hong; Tavakoli, Amirrasoul; Dai, Qing; Chakraborty, Sagnik; He, Chuan; Ans ... R01ES025987 DNA Repair (Amst) (2021 11) 34428697 Exiting the NIEHS site 2021 
Light-induced modulation of DNA recognition by the Rad4/XPC damage sensor protein.   Tavakoli, Amirrasoul; Paul, Debamita; Mu, Hong; Kuchlyan, Jagannath; Baral, Saroj; Ansari, Anj ... R01ES025987 RSC Chem Biol (2021 Apr 01) 34041491 Exiting the NIEHS site 2021 
Molecular dynamics simulations reveal how H3K56 acetylation impacts nucleosome structure to promote ...   Fu, Iwen; Geacintov, Nicholas E; Broyde, Suse R01ES025987 DNA Repair (Amst) (2021 11) 34399316 Exiting the NIEHS site 2021 
Translesion Synthesis Past 5-Formylcytosine-Mediated DNA-Peptide Cross-Links by hPolη Is Dependent o ...   Thomforde, Jenna; Fu, Iwen; Rodriguez, Freddys; Pujari, Suresh S; Broyde, Suse; Tretyakova, Na ... R01ES023350, R01ES025987 Biochemistry (2021 06 15) 34080848 Exiting the NIEHS site 2021 
Tethering-facilitated DNA 'opening' and complementary roles of β-hairpin motifs in the Rad4/XPC DNA ...   Paul, Debamita; Mu, Hong; Tavakoli, Amirrasoul; Dai, Qing; Chen, Xuejing; Chakraborty, Sagnik; ... R01ES025987 Nucleic Acids Res (2020 12 02) 33119737 Exiting the NIEHS site 2020 
The DNA damage-sensing NER repair factor XPC-RAD23B does not recognize bulky DNA lesions with a miss ...   Feher, Katie M; Kolbanovskiy, Alexander; Durandin, Alexander; Shim, Yoonjung; Min, Jung-Hyun; L ... R01ES025987 DNA Repair (Amst) (2020 12) 33035795 Exiting the NIEHS site 2020 
Variable impact of conformationally distinct DNA lesions on nucleosome structure and dynamics: Impli ...   Cai, Yuqin; Geacintov, Nicholas E; Broyde, Suse R01ES025987 DNA Repair (Amst) (2020 03) 32018112 Exiting the NIEHS site 2020 
5-Formylcytosine-induced DNA-peptide cross-links reduce transcription efficiency, but do not cause t ...   Ji, Shaofei; Park, Daeyoon; Kropachev, Konstantin; Kolbanovskiy, Marina; Fu, Iwen; Broyde, Sus ... R01ES023350, R01ES025987 J Biol Chem (2019 11 29) 31597704 Exiting the NIEHS site 2019 
Nucleotide Excision Repair and Impact of Site-Specific 5',8-Cyclopurine and Bulky DNA Lesions on the ...   Shafirovich, Vladimir; Kolbanovskiy, Marina; Kropachev, Konstantin; Liu, Zhi; Cai, Yuquin; Terz ... R01ES025987 Biochemistry (2019 02 12) 30570250 Exiting the NIEHS site 2019 
Rotational and translational positions determine the structural and dynamic impact of a single ribon ...   Fu, Iwen; Smith, Duncan J; Broyde, Suse R01ES025987 DNA Repair (Amst) (2019 01) 30522887 Exiting the NIEHS site 2019 
Structure and mechanism of pyrimidine-pyrimidone (6-4) photoproduct recognition by the Rad4/XPC nucl ...   Paul, Debamita; Mu, Hong; Zhao, Hong; Ouerfelli, Ouathek; Jeffrey, Philip D; Broyde, Suse; Min ... R01ES025987 Nucleic Acids Res (2019 07 09) 31106376 Exiting the NIEHS site 2019 
Transcriptional Bypass of DNA-Protein and DNA-Peptide Conjugates by T7 RNA Polymerase.   Ji, Shaofei; Thomforde, Jenna; Rogers, Colette; Fu, Iwen; Broyde, Suse; Tretyakova, Natalia Y R01ES023350, R01ES025987 ACS Chem Biol (2019 12 20) 31573793 Exiting the NIEHS site 2019 
5-Formylcytosine mediated DNA-protein cross-links block DNA replication and induce mutations in huma ...   Ji, Shaofei; Fu, Iwen; Naldiga, Spandana; Shao, Hongzhao; Basu, Ashis K; Broyde, Suse; Tretyak ... R01ES023350, R01ES025987 Nucleic Acids Res (2018 07 27) 29905846 Exiting the NIEHS site 2018 
Corrigendum: 5-Formylcytosine mediated DNA-protein cross-links block DNA replication and induce muta ...   Ji, Shaofei; Fu, Iwen; Naldiga, Spandana; Shao, Hongzhao; Basu, Ashis K; Broyde, Suse; Tretyak ... R01ES025987 Nucleic Acids Res (2018 Oct 12) 30184121 Exiting the NIEHS site 2018 
Enhanced spontaneous DNA twisting/bending fluctuations unveiled by fluorescence lifetime distributio ...   Chakraborty, Sagnik; Steinbach, Peter J; Paul, Debamita; Mu, Hong; Broyde, Suse; Min, Jung-Hyu ... R01ES025987 Nucleic Acids Res (2018 02 16) 29267981 Exiting the NIEHS site 2018 
Lesion Sensing during Initial Binding by Yeast XPC/Rad4: Toward Predicting Resistance to Nucleotide ...   Mu, Hong; Zhang, Yingkai; Geacintov, Nicholas E; Broyde, Suse R01ES025987 Chem Res Toxicol (2018 11 19) 30284444 Exiting the NIEHS site 2018 
Molecular basis for damage recognition and verification by XPC-RAD23B and TFIIH in nucleotide excisi ...   Mu, Hong; Geacintov, Nicholas E; Broyde, Suse; Yeo, Jung-Eun; Schärer, Orlando D R01ES025987 DNA Repair (Amst) (2018 11) 30174301 Exiting the NIEHS site 2018 
Synergistic effects of H3 and H4 nucleosome tails on structure and dynamics of a lesion-containing D ...   Cai, Yuqin; Fu, Iwen; Geacintov, Nicholas E; Zhang, Yingkai; Broyde, Suse R01ES025987 DNA Repair (Amst) (2018 May) 29631253 Exiting the NIEHS site 2018 
Nucleosome Histone Tail Conformation and Dynamics: Impacts of Lysine Acetylation and a Nearby Minor ...   Fu, Iwen; Cai, Yuqin; Geacintov, Nicholas E; Zhang, Yingkai; Broyde, Suse R01ES025987 Biochemistry (2017 Apr 11) 28304160 Exiting the NIEHS site 2017 
Nucleotide Excision Repair Lesion-Recognition Protein Rad4 Captures a Pre-Flipped Partner Base in a ...   Mu, Hong; Geacintov, Nicholas E; Min, Jung-Hyun; Zhang, Yingkai; Broyde, Suse R01ES025987 Chem Res Toxicol (2017 Jun 19) 28460163 Exiting the NIEHS site 2017 
Repair-Resistant DNA Lesions.   Geacintov, Nicholas E; Broyde, Suse R01ES025987 Chem Res Toxicol (2017 Aug 21) 28750166 Exiting the NIEHS site 2017 
The Nonbulky DNA Lesions Spiroiminodihydantoin and 5-Guanidinohydantoin Significantly Block Human RN ...   Kolbanovskiy, Marina; Chowdhury, Moinuddin A; Nadkarni, Aditi; Broyde, Suse; Geacintov, Nichola ... R01ES025987 Biochemistry (2017 Jun 20) 28514164 Exiting the NIEHS site 2017 
Bypass of DNA-Protein Cross-links Conjugated to the 7-Deazaguanine Position of DNA by Translesion Sy ...   Wickramaratne, Susith; Ji, Shaofei; Mukherjee, Shivam; Su, Yan; Pence, Matthew G; Lior-Hoffmann ... R01ES023350, R01ES025987 J Biol Chem (2016 Nov 04) 27621316 Exiting the NIEHS site 2016 
Back
to Top