Project Title: | MAPPING THE ALS EXPOSOME TO GAIN NEW INSIGHTS INTO DISEASE RISK AND PATHOGENESIS |
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PI: | Feldman, Eva Lucille |
Institution: | University Of Michigan At Ann Arbor |
Grant Number: | R01ES030049 |
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Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
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Environmental risk scores of persistent organic pollutants associate with higher ALS risk and shorte ... | Goutman, Stephen A; Boss, Jonathan; Jang, Dae-Gyu; Mukherjee, Bhramar; Richardson, Rudy J; Batt ... | R01ES030049 | J Neurol Neurosurg Psychiatry (2024 Feb 14) | 37758454 | 2024 |
Gut microbiome correlates with plasma lipids in amyotrophic lateral sclerosis. | Guo, Kai; Figueroa-Romero, Claudia; Noureldein, Mohamed H; Murdock, Benjamin J; Savelieff, Mash ... | R01ES030049 | Brain (2024 Feb 01) | 37721161 | 2024 |
Improving prediction models of amyotrophic lateral sclerosis (ALS) using polygenic, pre-existing con ... | Jin, Weijia; Boss, Jonathan; Bakulski, Kelly M; Goutman, Stephen A; Feldman, Eva L; Fritsche, ... | R01ES030049 | medRxiv (2024 Mar 30) | 38585910 | 2024 |
Metal mixtures associate with higher amyotrophic lateral sclerosis risk and mortality independent of ... | Jang, Dae Gyu; Dou, John; Koubek, Emily J; Teener, Samuel; Zhao, Lili; Bakulski, Kelly M; Mukh ... | R01ES030049 | medRxiv (2024 Feb 28) | 38464233 | 2024 |
Role of the Exposome in Neurodegenerative Disease: Recent Insights and Future Directions. | Sakowski, Stacey A; Koubek, Emily J; Chen, Kevin S; Goutman, Stephen A; Feldman, Eva L | R01ES030049 | Ann Neurol (2024 Apr) | 38411261 | 2024 |
Body mass index associates with amyotrophic lateral sclerosis survival and metabolomic profiles. | Goutman, Stephen A; Boss, Jonathan; Iyer, Gayatri; Habra, Hani; Savelieff, Masha G; Karnovsky, ... | R01ES030049 | Muscle Nerve (2023 Mar) | 36321729 | 2023 |
Cumulative Genetic Score and C9orf72 Repeat Status Independently Contribute to Amyotrophic Lateral S ... | Dou, John; Bakulski, Kelly; Guo, Kai; Hur, Junguk; Zhao, Lili; Saez-Atienzar, Sara; Stark, Al ... | P30ES017885, R01ES030049 | Neurol Genet (2023 Aug) | 37293291 | 2023 |
Gut microbiota in a mouse model of obesity and peripheral neuropathy associated with plasma and nerv ... | Guo, Kai; Figueroa-Romero, Claudia; Noureldein, Mohamed; Hinder, Lucy M; Sakowski, Stacey A; Ru ... | R01ES030049 | Microbiome (2023 Mar 15) | 36922895 | 2023 |
miRNA analysis reveals novel dysregulated pathways in amyotrophic lateral sclerosis. | Hur, Junguk; Paez-Colasante, Ximena; Figueroa-Romero, Claudia; Lo, Ting-Wen; Barmada, Sami J; P ... | R01ES030049 | Hum Mol Genet (2023 Mar 06) | 36219176 | 2023 |
Occupational history associates with ALS survival and onset segment. | Goutman, Stephen A; Boss, Jonathan; Godwin, Christopher; Mukherjee, Bhramar; Feldman, Eva L; Ba ... | P30ES017885, R01ES030049 | Amyotroph Lateral Scler Frontotemporal Degener (2023 May) | 36193557 | 2023 |
The amyotrophic lateral sclerosis exposome: recent advances and future directions. | Goutman, Stephen A; Savelieff, Masha G; Jang, Dae-Gyu; Hur, Junguk; Feldman, Eva L | R01ES030049 | Nat Rev Neurol (2023 Oct) | 37709948 | 2023 |
Amyotrophic lateral sclerosis. | Feldman, Eva L; Goutman, Stephen A; Petri, Susanne; Mazzini, Letizia; Savelieff, Masha G; Shaw, ... | R01ES030049 | Lancet (2022 Oct 15) | 36116464 | 2022 |
Associations of self-reported occupational exposures and settings to ALS: a case-control study. | Goutman, Stephen A; Boss, Jonathan; Godwin, Christopher; Mukherjee, Bhramar; Feldman, Eva L; Ba ... | P30ES017885, R01ES030049 | Int Arch Occup Environ Health (2022 Sep) | 35593931 | 2022 |
Emerging insights into the complex genetics and pathophysiology of amyotrophic lateral sclerosis. | Goutman, Stephen A; Hardiman, Orla; Al-Chalabi, Ammar; Chió, Adriano; Savelieff, Masha G; Kiern ... | R01ES030049 | Lancet Neurol (2022 May) | 35334234 | 2022 |
Metabolomics identifies shared lipid pathways in independent amyotrophic lateral sclerosis cohorts. | Goutman, Stephen A; Guo, Kai; Savelieff, Masha G; Patterson, Adam; Sakowski, Stacey A; Habra, ... | R01ES030049 | Brain (2022 Dec 19) | 35088843 | 2022 |
Recent advances in the diagnosis and prognosis of amyotrophic lateral sclerosis. | Goutman, Stephen A; Hardiman, Orla; Al-Chalabi, Ammar; Chió, Adriano; Savelieff, Masha G; Kiern ... | R01ES030049 | Lancet Neurol (2022 May) | 35334233 | 2022 |
Stem cell therapy for central nervous system disorders: Metabolic interactions between transplanted ... | Sakowski, Stacey A; Chen, Kevin S | R01ES030049 | Neurobiol Dis (2022 Oct 15) | 35988874 | 2022 |
Systems Biology to Address Unmet Medical Needs in Neurological Disorders. | Savelieff, Masha G; Noureldein, Mohamed H; Feldman, Eva L | R01ES030049 | Methods Mol Biol (2022) | 35437727 | 2022 |
Tofacitinib Suppresses Natural Killer Cells In Vitro and In Vivo: Implications for Amyotrophic Later ... | Figueroa-Romero, Claudia; Monteagudo, Alina; Murdock, Benjamin J; Famie, Joshua P; Webber-Davis, ... | R01ES030049 | Front Immunol (2022) | 35197969 | 2022 |
Variable selection with multiply-imputed datasets: choosing between stacked and grouped methods. | Du, Jiacong; Boss, Jonathan; Han, Peisong; Beesley, Lauren J; Kleinsasser, Michael; Goutman, S ... | P30ES017885, R01ES030049 | J Comput Graph Stat (2022) | 36644406 | 2022 |
Interplay between immunity and amyotrophic lateral sclerosis: Clinical impact. | De Marchi, Fabiola; Munitic, Ivana; Amedei, Amedeo; Berry, James D; Feldman, Eva L; Aronica, E ... | R01ES030049 | Neurosci Biobehav Rev (2021 Aug) | 34153344 | 2021 |
NK cells associate with ALS in a sex- and age-dependent manner. | Murdock, Benjamin J; Famie, Joshua P; Piecuch, Caroline E; Pawlowski, Kristen D; Mendelson, Fay ... | R01ES030049 | JCI Insight (2021 Jun 08) | 33974561 | 2021 |
Untargeted metabolomics yields insight into ALS disease mechanisms. | Goutman, Stephen A; Boss, Jonathan; Guo, Kai; Alakwaa, Fadhl M; Patterson, Adam; Kim, Sehee; S ... | R01ES030049 | J Neurol Neurosurg Psychiatry (2020 Dec) | 32928939 | 2020 |