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Who We Fund: Publication Detail

Project Title: DEVELOPMENTAL FLAME RETARDANT EXPOSURE, GUT MICROBIOME, AND OBESITY
PI: Cui, Yue
Institution: University Of Washington
Grant Number: R01ES030197

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Viewing 28 publications
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Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Maternal PBDE exposure disrupts gut microbiome and promotes hepatic proinflammatory signaling in hum ...   Kim, Sarah; Li, Hao; Jin, Yan; Armad, Jasmine; Gu, Haiwei; Mani, Sridhar; Cui, Julia Y P30ES007033, R01ES030197, R01ES031098 Toxicol Sci (2023 Jul 28) 37267213 Exiting the NIEHS site 2023 
Microbial Metabolites as Ligands to Xenobiotic Receptors: Chemical Mimicry as Potential Drugs of the ...   Dvořák, Zdeněk; Li, Hao; Mani, Sridhar R01ES030197 Drug Metab Dispos (2023 Feb) 36184080 Exiting the NIEHS site 2023 
Recent Review on Selected Xenobiotics and Their Impacts on Gut Microbiome and Metabolome.   Jin, Yan; Chi, Jinhua; LoMonaco, Kaelene; Boon, Alexandria; Gu, Haiwei R01ES030197 Trends Analyt Chem (2023 Sep) 37484879 Exiting the NIEHS site 2023 
SOX17 Deficiency Mediates Pulmonary Hypertension: At the Crossroads of Sex, Metabolism, and Genetics ...   Sangam, Shreya; Sun, Xutong; Schwantes-An, Tae-Hwi; Yegambaram, Manivannan; Lu, Qing; Shi, Yin ... R01ES030197 Am J Respir Crit Care Med (2023 Apr 15) 36913491 Exiting the NIEHS site 2023 
Effect of Chronic Cadmium Exposure on Brain and Liver Transporters and Drug-Metabolizing Enzymes in ...   Wang, Hao; Zhang, Liang; Xia, Zhengui; Cui, Julia Yue P30ES007033, R01ES030197, R01ES031098 Drug Metab Dispos (2022 Oct) 35878927 Exiting the NIEHS site 2022 
Perfluorinated Carboxylic Acids with Increasing Carbon Chain Lengths Upregulate Amino Acid Transport ...   Lim, Joe Jongpyo; Suh, Youjun; Faustman, Elaine M; Cui, Julia Yue P30ES007033, R01ES030197, R01ES031098, T32ES007032 Drug Metab Dispos (2022 Oct) 34857530 Exiting the NIEHS site 2022 
Pregnane X Receptor and the Gut-Liver Axis: A Recent Update.   Dutta, Moumita; Lim, Joe Jongpyo; Cui, Julia Yue P30ES005605, P30ES007033, R01ES030197, R01ES031098, T32ES007032 Drug Metab Dispos (2022 Apr) 34862253 Exiting the NIEHS site 2022 
An Inexpensive Imaging Platform to Record and Quantitate Bacterial Swarming.   Chen, Weijie; Mani, Sridhar; Tang, Jay X R01ES030197 Bio Protoc (2021 Sep 20) 34692912 Exiting the NIEHS site 2021 
Bacterial Swarmers Enriched During Intestinal Stress Ameliorate Damage.   De, Arpan; Chen, Weijie; Li, Hao; Wright, Justin R; Lamendella, Regina; Lukin, Dana J; Szymcza ... R01ES030197 Gastroenterology (2021 07) 33741315 Exiting the NIEHS site 2021 
Cadmium exposure modulates the gut-liver axis in an Alzheimer's disease mouse model.   Zhang, Angela; Matsushita, Megumi; Zhang, Liang; Wang, Hao; Shi, Xiaojian; Gu, Haiwei; Xia, Z ... P30ES007033, R01ES030197, R01ES031098, T32ES007032, T32ES015459 Commun Biol (2021 Dec 15) 34912029 Exiting the NIEHS site 2021 
Confinement discerns swarmers from planktonic bacteria.   Chen, Weijie; Mani, Neha; Karani, Hamid; Li, Hao; Mani, Sridhar; Tang, Jay X R01ES030197 Elife (2021 04 22) 33884952 Exiting the NIEHS site 2021 
Deciphering structural bases of intestinal and hepatic selectivity in targeting pregnane X receptor ...   Li, Hao; Illés, Peter; Karunaratne, Chamini V; Nordstrøm, Lars Ulrik; Luo, Xiaoping; Yang, Ann ... R01ES030197 Bioorg Chem (2021 Apr) 33636438 Exiting the NIEHS site 2021 
Enhanced Detection of Short-Chain Fatty Acids Using Gas Chromatography Mass Spectrometry.   Gu, Haiwei; Jasbi, Paniz; Patterson, Jeffrey; Jin, Yan R01ES030197 Curr Protoc (2021 Jun) 34165916 Exiting the NIEHS site 2021 
Neonatal Exposure to BPA, BDE-99, and PCB Produces Persistent Changes in Hepatic Transcriptome Assoc ...   Lim, Joe Jongpyo; Dutta, Moumita; Dempsey, Joseph L; Lehmler, Hans-Joachim; MacDonald, James; B ... P30ES005605, P30ES007033, P30ES030285, R01ES030197, R01ES031098, T32ES007032 Toxicol Sci (2021 Oct 27) 34453844 Exiting the NIEHS site 2021 
Nontarget analysis reveals gut microbiome-dependent differences in the fecal PCB metabolite profiles ...   Li, Xueshu; Liu, Yanna; Martin, Jonathan W; Cui, Julia Yue; Lehmler, Hans-Joachim P30ES005605, P30ES007033, P42ES013661, R01ES014901, R01ES030197, R01ES031098 Environ Pollut (2021 Jan 01) 33032095 Exiting the NIEHS site 2021 
Pregnane X receptor exacerbates nonalcoholic fatty liver disease accompanied by obesity- and inflamm ...   Kim, Sarah; Choi, Sora; Dutta, Moumita; Asubonteng, Jeffrey O; Polunas, Marianne; Goedken, Mic ... P30ES005605, P30ES007033, R01ES030197, R01ES031098 Biochem Pharmacol (2021 Nov) 34303710 Exiting the NIEHS site 2021 
Comprehensive Isotopic Targeted Mass Spectrometry: Reliable Metabolic Flux Analysis with Broad Cover ...   Shi, Xiaojian; Xi, Bowei; Jasbi, Paniz; Turner, Cassidy; Jin, Yan; Gu, Haiwei R01ES030197 Anal Chem (2020 Sep 01) 32697570 Exiting the NIEHS site 2020 
Drug Mimicry: Promiscuous Receptors PXR and AhR, and Microbial Metabolite Interactions in the Intest ...   Dvořák, Zdeněk; Sokol, Harry; Mani, Sridhar R01ES030197 Trends Pharmacol Sci (2020 12) 33097284 Exiting the NIEHS site 2020 
Garcinoic Acid Is a Natural and Selective Agonist of Pregnane X Receptor.   Bartolini, Desirée; De Franco, Francesca; Torquato, Pierangelo; Marinelli, Rita; Cerra, Bruno; ... R01ES030197 J Med Chem (2020 04 09) 32160459 Exiting the NIEHS site 2020 
Garcinoic acid prevents β-amyloid (Aβ) deposition in the mouse brain.   Marinelli, Rita; Torquato, Pierangelo; Bartolini, Desirée; Mas-Bargues, Cristina; Bellezza, Gui ... R01ES030197 J Biol Chem (2020 08 14) 32616652 Exiting the NIEHS site 2020 
Gut Microbiome Critically Impacts PCB-induced Changes in Metabolic Fingerprints and the Hepatic Tran ...   Lim, Joe Jongpyo; Li, Xueshu; Lehmler, Hans-Joachim; Wang, Dongfang; Gu, Haiwei; Cui, Julia Yu ... P30ES005605, P30ES007033, P42ES013661, R01ES030197, R01ES031098, T32ES007032 Toxicol Sci (2020 09 01) 32544245 Exiting the NIEHS site 2020 
Human microbial metabolite mimicry as a strategy to expand the chemical space of potential drugs.   Li, Hao; Ranhotra, Harmit S; Mani, Sridhar; Dvořák, Zdeněk; Sokol, Harry; Müller, Rolf R01ES030197 Drug Discov Today (2020 Sep) 32562605 Exiting the NIEHS site 2020 
Targeting the pregnane X receptor using microbial metabolite mimicry.   Dvořák, Zdeněk; Kopp, Felix; Costello, Cait M; Kemp, Jazmin S; Li, Hao; Vrzalová, Aneta; Štěpá ... P30ES007033, R01ES030197, R35ES028244 EMBO Mol Med (2020 Apr 07) 32153125 Exiting the NIEHS site 2020 
Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs.   Dvorak, Zdenek; Klapholz, Max; Burris, Thomas P; Willing, Benjamin P; Gioiello, Antimo; Pellicc ... R01ES030197 Mol Pharmacol (2020 Oct) 32764096 Exiting the NIEHS site 2020 
Gut microbiome: An intermediary to neurotoxicity.   Dempsey, Joseph L; Little, Mallory; Cui, Julia Yue R01ES030197, T32ES007032 Neurotoxicology (2019 12) 31454513 Exiting the NIEHS site 2019 
Microbiome is a functional modifier of P450 drug metabolism.   Dempsey, Joseph L; Cui, Julia Yue R01ES030197 Curr Pharmacol Rep (2019 Dec) 33312848 Exiting the NIEHS site 2019 
Polybrominated Diphenyl Ethers and Gut Microbiome Modulate Metabolic Syndrome-Related Aqueous Metabo ...   Scoville, David K; Li, Cindy Yanfei; Wang, Dongfang; Dempsey, Joseph L; Raftery, Daniel; Mani, ... P30ES007033, R01ES030197, T32ES007032 Drug Metab Dispos (2019 08) 31123037 Exiting the NIEHS site 2019 
Pregnane X Receptor Activation Triggers Rapid ATP Release in Primed Macrophages That Mediates NLRP3 ...   Hudson, Grace; Flannigan, Kyle L; Venu, Vivek Krishna Pulakazhi; Alston, Laurie; Sandall, Chris ... R01ES030197 J Pharmacol Exp Ther (2019 07) 31004077 Exiting the NIEHS site 2019 
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