| Project Title: | REPLICATION FORK DYNAMICS AND REPAIR BY RAD51 PARALOGUES AFTER DNA ALKYLATION |
|---|---|
| PI: | Bernstein, Kara A |
| Institution: | University Of Pennsylvania |
| Grant Number: | R01ES030335 |
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Viewing 14 publications
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| Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
|---|---|---|---|---|---|
| Genetic and physical interactions reveal overlapping and distinct contributions to meiotic double-st ... | Raices, Marilina; Balmir, Fabiola; Silva, Nicola; Li, Wei; Grundy, McKenzie K; Hoffman, Dane K ... | R01ES030335 | bioRxiv (2024 Feb 28) |
38463951
|
2024 |
| Variants in the first methionine of RAD51C are homologous recombination proficient due to an alterna ... | Rein, Hayley L; Bernstein, Kara A | R01ES030335, R01ES031796 | DNA Repair (Amst) (2024 Mar) |
38330859
|
2024 |
| Structural insights into BCDX2 complex function in homologous recombination. | Rawal, Yashpal; Jia, Lijia; Meir, Aviv; Zhou, Shuo; Kaur, Hardeep; Ruben, Eliza A; Kwon, Youn ... | P30ES013508, R01ES007061, R01ES030335, R01ES031796 | Nature (2023 Jul) |
37344589
|
2023 |
| Unlicensed origin DNA melting by MCV and SV40 polyomavirus LT proteins is independent of ATP-depende ... | Wan, Li; Toland, Sabrina; Robinson-McCarthy, Lindsey R; Lee, Nara; Schaich, Matthew A; Hengel, ... | R01ES030335, R01ES031796, R35ES031638 | Proc Natl Acad Sci U S A (2023 Jul 25) |
37459531
|
2023 |
| Hrq1/RECQL4 regulation is critical for preventing aberrant recombination during DNA intrastrand cros ... | Luong, Thong T; Li, Zheqi; Priedigkeit, Nolan; Parker, Phoebe S; Böhm, Stefanie; Rapchak, Kyle ... | R01ES030335 | PLoS Genet (2022 Sep) |
36126066
|
2022 |
| Aldehyde dehydrogenase inhibitors promote DNA damage in ovarian cancer and synergize with ATM/ATR in ... | Grimley, Edward; Cole, Alexander J; Luong, Thong T; McGonigal, Stacy C; Sinno, Sarah; Yang, Do ... | R01ES030335, R01ES031796 | Theranostics (2021) |
33664846
|
2021 |
| Distinct pathways of homologous recombination controlled by the SWS1-SWSAP1-SPIDR complex. | Prakash, Rohit; Sandoval, Thomas; Morati, Florian; Zagelbaum, Jennifer A; Lim, Pei-Xin; White, ... | R01ES030335 | Nat Commun (2021 Jul 12) |
34253720
|
2021 |
| Long-term survival of an ovarian cancer patient harboring a RAD51C missense mutation. | Sullivan, Meghan R; Prakash, Rohit; Rawal, Yashpal; Wang, Weibin; Sung, Patrick; Radke, Marc R ... | R01ES007061, R01ES030335, R01ES031796 | Cold Spring Harb Mol Case Stud (2021 Apr) |
33832919
|
2021 |
| RAD51 paralog function in replicative DNA damage and tolerance. | Rein, Hayley L; Bernstein, Kara A; Baldock, Robert A | R01ES030335, R01ES031796 | Curr Opin Genet Dev (2021 Dec) |
34311385
|
2021 |
| Role and Regulation of the RECQL4 Family during Genomic Integrity Maintenance. | Luong, Thong T; Bernstein, Kara A | R01ES030335 | Genes (Basel) (2021 Nov 29) |
34946868
|
2021 |
| The Shu complex prevents mutagenesis and cytotoxicity of single-strand specific alkylation lesions. | Bonilla, Braulio; Brown, Alexander J; Hengel, Sarah R; Rapchak, Kyle S; Mitchell, Debra; Pressi ... | R01ES030335 | Elife (2021 11 01) |
34723799
|
2021 |
| MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA ... | Huang, Jen-Wei; Acharya, Ananya; Taglialatela, Angelo; Nambiar, Tarun S; Cuella-Martin, Raquel; ... | R01ES030335 | Nat Commun (2020 Jun 11) |
32528060
|
2020 |
| RAD51 Gene Family Structure and Function. | Bonilla, Braulio; Hengel, Sarah R; Grundy, McKenzie K; Bernstein, Kara A | R01ES030335 | Annu Rev Genet (2020 11 23) |
32663049
|
2020 |
| Regulation and pharmacological targeting of RAD51 in cancer. | Grundy, McKenzie K; Buckanovich, Ronald J; Bernstein, Kara A | R01ES030335 | NAR Cancer (2020 Sep) |
33015624
|
2020 |