Project Title: | INFLUENCE OF GERMLINE MUTATIONS ON SUSCEPTIBILITY TO ENVIRONMENTAL CARCINOGENS |
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PI: | Carbone, Michele |
Institution: | University Of Hawaii At Manoa |
Grant Number: | R01ES030948 |
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Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
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BAP1 is a novel regulator of HIF-1α. | Bononi, Angela; Wang, Qian; Zolondick, Alicia A; Bai, Fang; Steele-Tanji, Mika; Suarez, Joelle ... | R01ES030948 | Proc Natl Acad Sci U S A (2023 Jan 24) | 36656861 | 2023 |
Did the Ban on Asbestos Reduce the Incidence of Mesothelioma? | Carbone, Michele; Yang, Haining; Pass, Harvey I; Taioli, Emanuela | R01ES030948 | J Thorac Oncol (2023 Jun) | 37210180 | 2023 |
HMGB1 released by mesothelial cells drives the development of asbestos-induced mesothelioma. | Suarez, Joelle S; Novelli, Flavia; Goto, Keisuke; Ehara, Michiko; Steele, Mika; Kim, Jin-Hee; ... | R01ES030948 | Proc Natl Acad Sci U S A (2023 Sep 26) | 37729199 | 2023 |
Preventive and therapeutic opportunities: targeting BAP1 and/or HMGB1 pathways to diminish the burde ... | Carbone, Michele; Minaai, Michael; Takinishi, Yasutaka; Pagano, Ian; Yang, Haining | R01ES030948 | J Transl Med (2023 Oct 25) | 37880686 | 2023 |
Medical and Surgical Care of Patients With Mesothelioma and Their Relatives Carrying Germline BAP1 M ... | Carbone, Michele; Pass, Harvey I; Ak, Guntulu; Alexander Jr, H Richard; Baas, Paul; Baumann, F ... | R01ES030948 | J Thorac Oncol (2022 Jul) | 35462085 | 2022 |
Naturally occurring metals in unregulated domestic wells in Nevada, USA. | Arienzo, Monica M; Saftner, Daniel; Bacon, Steven N; Robtoy, Erika; Neveux, Iva; Schlauch, Kar ... | R01ES030948 | Sci Total Environ (2022 Dec 10) | 36029812 | 2022 |
Asbestos-induced chronic inflammation in malignant pleural mesothelioma and related therapeutic appr ... | Zolondick, Alicia A; Gaudino, Giovanni; Xue, Jiaming; Pass, Harvey I; Carbone, Michele; Yang, ... | R01ES030948 | Precis Cancer Med (2021 Sep) | 35098108 | 2021 |
BAP1 forms a trimer with HMGB1 and HDAC1 that modulates gene × environment interaction with asbestos ... | Novelli, Flavia; Bononi, Angela; Wang, Qian; Bai, Fang; Patergnani, Simone; Kricek, Franz; Hag ... | R01ES030948 | Proc Natl Acad Sci U S A (2021 Nov 30) | 34815344 | 2021 |
Coronavirus 2019 Infectious Disease Epidemic: Where We Are, What Can Be Done and Hope For. | Carbone, Michele; Lednicky, John; Xiao, Shu-Yuan; Venditti, Mario; Bucci, Enrico | R01ES030948 | J Thorac Oncol (2021 Apr) | 33422679 | 2021 |
HMGB1 as a therapeutic target in disease. | Xue, Jiaming; Suarez, Joelle S; Minaai, Michael; Li, Shuangjing; Gaudino, Giovanni; Pass, Harv ... | R01ES030948 | J Cell Physiol (2021 05) | 33107103 | 2021 |
Asbestos induces mesothelial cell transformation via HMGB1-driven autophagy. | Xue, Jiaming; Patergnani, Simone; Giorgi, Carlotta; Suarez, Joelle; Goto, Keisuke; Bononi, Ang ... | R01ES030948 | Proc Natl Acad Sci U S A (2020 10 13) | 32999071 | 2020 |
Biological Mechanisms and Clinical Significance of BAP1 Mutations in Human Cancer. | Carbone, Michele; Harbour, J William; Brugarolas, James; Bononi, Angela; Pagano, Ian; Dey, Anw ... | R01ES030948 | Cancer Discov (2020 Aug) | 32690542 | 2020 |
Heterozygous germline BLM mutations increase susceptibility to asbestos and mesothelioma. | Bononi, Angela; Goto, Keisuke; Ak, Guntulu; Yoshikawa, Yoshie; Emi, Mitsuru; Pastorino, Sandra ... | R01ES030948 | Proc Natl Acad Sci U S A (2020 Dec 29) | 33318203 | 2020 |
Tumour predisposition and cancer syndromes as models to study gene-environment interactions. | Carbone, Michele; Arron, Sarah T; Beutler, Bruce; Bononi, Angela; Cavenee, Webster; Cleaver, J ... | R01ES030948 | Nat Rev Cancer (2020 Sep) | 32472073 | 2020 |