Project Title: | MANGANESE EXPOSURE SUSCEPTIBILITY AS A MODIFIER OF EXCITOTOXICITY IN ALZHEIMER'S DISEASE |
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PI: | Harrison, Fiona Edith |
Institution: | Vanderbilt University Medical Center |
Grant Number: | R01ES031401 |
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Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
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A simulative deep learning model of SNP interactions on chromosome 19 for predicting Alzheimer's dis ... | Bae, Jinhyeong; Logan, Paige E; Acri, Dominic J; Bharthur, Apoorva; Nho, Kwangsik; Saykin, And ... | R01ES031401 | Alzheimers Dement (2023 Dec) | 37409680 | 2023 |
Acute manganese exposure impairs glutamatergic function in a young mouse model of Alzheimer's diseas ... | Spitznagel, Brittany D; Buchanan, Rebecca A; Consoli, David C; Thibert, Megan K; Bowman, Aaron ... | R01ES031401, T32ES007028 | Neurotoxicology (2023 Mar) | 36621467 | 2023 |
Altered EEG, disrupted hippocampal long-term potentiation and neurobehavioral deficits implicate a d ... | Consoli, David C; Spitznagel, Brittany D; Owen, Benjamin M; Kang, Hakmook; Williams Roberson, S ... | R01ES031401 | Brain Behav Immun (2023 Jan) | 36243287 | 2023 |
Exposing the role of metals in neurological disorders: a focus on manganese. | Kim, Hyunjin; Harrison, Fiona E; Aschner, Michael; Bowman, Aaron B | R01ES007331, R01ES010563, R01ES031401 | Trends Mol Med (2022 Jul) | 35610122 | 2022 |
Manganese-induced hyperactivity and dopaminergic dysfunction depend on age, sex and YAC128 genotype. | Wilcox, Jordyn M; Consoli, David C; Paffenroth, Krista C; Spitznagel, Brittany D; Calipari, Eri ... | R01ES010563, R01ES031401 | Pharmacol Biochem Behav (2022 Feb) | 35063467 | 2022 |
Ascorbate deficiency decreases dopamine release in gulo-/- and APP/PSEN1 mice. | Consoli, David C; Brady, Lillian J; Bowman, Aaron B; Calipari, Erin S; Harrison, Fiona E | R01ES031401 | J Neurochem (2021 May) | 32797675 | 2021 |
Hyperexcitability and Pharmacological Responsiveness of Cortical Neurons Derived from Human iPSCs Ca ... | Que, Zhefu; Olivero-Acosta, Maria I; Zhang, Jingliang; Eaton, Muriel; Tukker, Anke M; Chen, Xi ... | R01ES031401 | J Neurosci (2021 12 08) | 34716231 | 2021 |
Novel test strategies for in vitro seizure liability assessment. | Tukker, Anke M; Westerink, Remco H S | R01ES031401 | Expert Opin Drug Metab Toxicol (2021 Aug) | 33595380 | 2021 |
YAC128 mouse model of Huntington disease is protected against subtle chronic manganese (Mn)-induced ... | Wilcox, Jordyn M; Pfalzer, Anna C; Tienda, Adriana A; Debbiche, Ines F; Cox, Ellen C; Totten, ... | R01ES031401, T32ES007028 | Neurotoxicology (2021 Dec) | 34543681 | 2021 |
Brain manganese and the balance between essential roles and neurotoxicity. | Balachandran, Rekha C; Mukhopadhyay, Somshuvra; McBride, Danielle; Veevers, Jennifer; Harrison, ... | P30ES026529, R01ES010563, R01ES024812, R01ES031401 | J Biol Chem (2020 May 08) | 32188696 | 2020 |