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Your Environment. Your Health.

Who We Fund: Publication Detail

Project Title: CYP2B6 INHIBITORS PERTURB PROPER DISTRIBUTION OF LIPIDS LEADING TO OBESITY AND FATTY LIVER DISEASE
PI: Baldwin, William S
Institution: Clemson University
Grant Number: R15ES017321

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 29 publications
Export to Excel (http://www.niehs.nih.gov//portfolio/index.cfm/portfolio/grantpubdetail/grant_number/R15ES017321/format/excel)
Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Gender differences in diet-induced steatotic disease in Cyp2b-null mice.   Heintz, Melissa M; McRee, Rebecca; Kumar, Ramiya; Baldwin, William S R15ES017321, R15ES017321 PLoS One (2020) 32155178 Exiting the NIEHS site 2020 
Chemical Activation of the Constitutive Androstane Receptor Leads to Activation of Oxidant-Induced N ...   Rooney, John P; Oshida, Keiyu; Kumar, Ramiya; Baldwin, William S; Corton, J Christopher R15ES017321, R15ES017321 Toxicol Sci (2019 01 01) 30203046 Exiting the NIEHS site 2019 
Cyp2b-null male mice are susceptible to diet-induced obesity and perturbations in lipid homeostasis.   Heintz, Melissa M; Kumar, Ramiya; Rutledge, Meredith M; Baldwin, William S R15ES017321, R15ES017321 J Nutr Biochem (2019 08) 31202118 Exiting the NIEHS site 2019 
Phase 0 of the Xenobiotic Response: Nuclear Receptors and Other Transcription Factors as a First Ste ...   Baldwin, William S R15ES017321, R15ES017321 Nucl Receptor Res (2019) 31815118 Exiting the NIEHS site 2019 
Cyp2b-Knockdown Mice Poorly Metabolize Corn Oil and Are Age-Dependent Obese.   Damiri, Basma; Baldwin, William S R15ES017321, R15ES017321 Lipids (2018 09) 30421529 Exiting the NIEHS site 2018 
High fat diet induced obesity is mitigated in Cyp3a-null female mice.   Kumar, Ramiya; Litoff, Elizabeth J; Boswell, W Tyler; Baldwin, William S R15ES017321, R15ES017321 Chem Biol Interact (2018 Jun 01) 29738703 Exiting the NIEHS site 2018 
Non-Mammalian Nuclear Receptors: From Evolution to Human Disease.   Gissendanner, Chris R; Baldwin, William S; Schaaf, Marcel J M R15ES017321, R15ES017321 Nucl Receptor Res (2018) 30221173 Exiting the NIEHS site 2018 
Annotation of the Nuclear Receptors in an Estuarine Fish species, Fundulus heteroclitus.   Baldwin, William S; Boswell, W Tyler; Ginjupalli, Gautam; Litoff, Elizabeth J R15ES017321, R15ES017321 Nucl Receptor Res (2017) 28804711 Exiting the NIEHS site 2017 
Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-n ...   Kumar, Ramiya; Mota, Linda C; Litoff, Elizabeth J; Rooney, John P; Boswell, W Tyler; Courter, ... R15ES017321, R15ES017321 PLoS One (2017) 28350814 Exiting the NIEHS site 2017 
Exchange of polar lipids from adults to neonates in Daphnia magna: Perturbations in sphingomyelin al ...   Sengupta, Namrata; Reardon, Delaney C; Gerard, Patrick D; Baldwin, William S R15ES017321, R15ES017321 PLoS One (2017) 28542405 Exiting the NIEHS site 2017 
RNA sequencing indicates that atrazine induces multiple detoxification genes in Daphnia magna and th ...   Schmidt, Allison M; Sengupta, Namrata; Saski, Christopher A; Noorai, Rooksana E; Baldwin, Willi ... R15ES017321, R15ES017321 Chemosphere (2017 Dec) 28968576 Exiting the NIEHS site 2017 
Perturbations in polar lipids, starvation survival and reproduction following exposure to unsaturate ...   Sengupta, Namrata; Gerard, Patrick D; Baldwin, William S R15ES017321, R15ES017321 Chemosphere (2016 Feb) 26606184 Exiting the NIEHS site 2016 
Arachidonic acid enhances reproduction in Daphnia magna and mitigates changes in sex ratios induced ...   Ginjupalli, Gautam K; Gerard, Patrick D; Baldwin, William S R15ES017321, R15ES017321 Environ Toxicol Chem (2015 Mar) 25393616 Exiting the NIEHS site 2015 
Repression of multiple CYP2D genes in mouse primary hepatocytes with a single siRNA construct.   Elraghy, Omaima; Baldwin, William S R15ES017321, R15ES017321 In Vitro Cell Dev Biol Anim (2015 Jan) 25124873 Exiting the NIEHS site 2015 
The HR96 activator, atrazine, reduces sensitivity of D. magna to triclosan and DHA.   Sengupta, Namrata; Litoff, Elizabeth J; Baldwin, William S R15ES017321, R15ES017321 Chemosphere (2015 Jun) 25747156 Exiting the NIEHS site 2015 
Annotation of the Daphnia magna nuclear receptors: comparison to Daphnia pulex.   Litoff, Elizabeth J; Garriott, Travis E; Ginjupalli, Gautam K; Butler, LaToya; Gay, Claudy; Sco ... R15ES017321, R15ES017321 Gene (2014 Nov 15) 25239664 Exiting the NIEHS site 2014 
The HR97 (NR1L) group of nuclear receptors: a new group of nuclear receptors discovered in Daphnia s ...   Li, Yangchun; Ginjupalli, Gautam K; Baldwin, William S R15ES017321, R15ES017321 Gen Comp Endocrinol (2014 Sep 15) 25092536 Exiting the NIEHS site 2014 
The time- and age-dependent effects of the juvenile hormone analog pesticide, pyriproxyfen on Daphni ...   Ginjupalli, Gautam K; Baldwin, William S R15ES017321, R15ES017321 Chemosphere (2013 Aug) 23714148 Exiting the NIEHS site 2013 
Daphnia HR96 is a promiscuous xenobiotic and endobiotic nuclear receptor.   Karimullina, Elina; Li, Yangchun; Ginjupalli, Gautam K; Baldwin, William S R15ES017321, R15ES017321 Aquat Toxicol (2012 Jul 15) 22466357 Exiting the NIEHS site 2012 
Lentiviral-mediated RNAi knockdown yields a novel mouse model for studying Cyp2b function.   Damiri, Basma; Holle, Eric; Yu, Xianzhong; Baldwin, William S R15ES017321, R15ES017321 Toxicol Sci (2012 Feb) 22083726 Exiting the NIEHS site 2012 
Nonylphenol-mediated CYP induction is PXR-dependent: The use of humanized mice and human hepatocytes ...   Mota, Linda C; Barfield, Christina; Hernandez, Juan P; Baldwin, William S R15ES017321, R15ES017321 Toxicol Appl Pharmacol (2011 May 1) 21376070 Exiting the NIEHS site 2011 
Selective imaging and killing of cancer cells with protein-activated near-infrared fluorescing nanop ...   Rungta, Parul; Bandera, Yuriy P; Roeder, Ryan D; Li, Yangchun; Baldwin, William S; Sharma, Dee ... R15ES017321, R15ES017321 Macromol Biosci (2011 Jul 07) 21480531 Exiting the NIEHS site 2011 
Constitutive androstane receptor -null mice are sensitive to the toxic effects of parathion: associa ...   Mota, Linda C; Hernandez, Juan P; Baldwin, William S R15ES017321, R15ES017321 Drug Metab Dispos (2010 Sep) 20573718 Exiting the NIEHS site 2010 
Dose-responsive gene expression changes in juvenile and adult mummichogs (Fundulus heteroclitus) aft ...   Gonzalez, Horacio O; Hu, Jianjun; Gaworecki, Kristen M; Roling, Jonathan A; Baldwin, William S; ... R15ES017321, R15ES017321 Mar Environ Res (2010 Aug) 20451245 Exiting the NIEHS site 2010 
Integrating omic technologies into aquatic ecological risk assessment and environmental monitoring: ...   Van Aggelen, Graham; Ankley, Gerald T; Baldwin, William S; Bearden, Daniel W; Benson, William H ... R15ES017321, R15ES017321 Environ Health Perspect (2010 Jan) 20056575 Exiting the NIEHS site 2010 
Interactions of the crustacean nuclear receptors HR3 and E75 in the regulation of gene transcription ...   Hannas, Bethany R; Wang, Ying H; Baldwin, William S; Li, Yangchun; Wallace, Andrew D; LeBlanc, ... R15ES017321, R15ES017321, T32ES007046 Gen Comp Endocrinol (2010 Jun 1) 20346363 Exiting the NIEHS site 2010 
A concentration addition model for the activation of the constitutive androstane receptor by xenobio ...   Baldwin, William S; Roling, Jonathan A R15ES017321, R15ES017321 Toxicol Sci (2009 Jan) 18832183 Exiting the NIEHS site 2009 
Activation of CAR and PXR by Dietary, Environmental and Occupational Chemicals Alters Drug Metabolis ...   Hernandez, J P; Mota, L C; Baldwin, W S R15ES017321, R15ES017321 Curr Pharmacogenomics Person Med (2009 Jun 01) 20871735 Exiting the NIEHS site 2009 
Sexually dimorphic regulation and induction of P450s by the constitutive androstane receptor (CAR).   Hernandez, J P; Mota, L C; Huang, W; Moore, D D; Baldwin, W S R15ES017321, R15ES017321 Toxicology (2009 Feb 4) 19041682 Exiting the NIEHS site 2009 
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