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Who We Fund: Publication Detail

Project Title: PROTEIN KINASE SIGNALING IN THE GENOTOXIC STRESS RESPONSE
PI: Yaffe, Michael B
Institution: Massachusetts Institute Of Technology
Grant Number: R35ES028374

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 18 publications
Export to Excel (http://www.niehs.nih.gov//portfolio/index.cfm/portfolio/grantpubdetail/grant_number/R35ES028374/format/excel)
Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
BRD4 prevents the accumulation of R-loops and protects against transcription-replication collision e ...   Lam, Fred C; Kong, Yi Wen; Huang, Qiuying; Vu Han, Tu-Lan; Maffa, Amanda D; Kasper, Ekkehard M ... R35ES028374 Nat Commun (2020 08 14) 32796829 Exiting the NIEHS site 2020 
Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide exc ...   Kong, Yi Wen; Dreaden, Erik C; Morandell, Sandra; Zhou, Wen; Dhara, Sanjeev S; Sriram, Ganapat ... R35ES028374 Nat Commun (2020 08 17) 32807787 Exiting the NIEHS site 2020 
Monitoring and modeling of lymphocytic leukemia cell bioenergetics reveals decreased ATP synthesis d ...   Kang, Joon Ho; Katsikis, Georgios; Li, Zhaoqi; Sapp, Kiera M; Stockslager, Max A; Lim, Daniel; ... R35ES028374 Nat Commun (2020 10 05) 33020492 Exiting the NIEHS site 2020 
Redox priming promotes Aurora A activation during mitosis.   Lim, Daniel C; Joukov, Vladimir; Rettenmaier, T Justin; Kumagai, Akiko; Dunphy, William G; Well ... R35ES028374 Sci Signal (2020 07 21) 32694171 Exiting the NIEHS site 2020 
Transite: A Computational Motif-Based Analysis Platform That Identifies RNA-Binding Proteins Modulat ...   Krismer, Konstantin; Bird, Molly A; Varmeh, Shohreh; Handly, Erika D; Gattinger, Anna; Bernwink ... R35ES028374 Cell Rep (2020 08 25) 32846122 Exiting the NIEHS site 2020 
Comprehensive profiling of the STE20 kinase family defines features essential for selective substrat ...   Miller, Chad J; Lou, Hua Jane; Simpson, Craig; van de Kooij, Bert; Ha, Byung Hak; Fisher, Oria ... R35ES028374 PLoS Biol (2019 03) 30897078 Exiting the NIEHS site 2019 
Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling o ...   van de Kooij, Bert; Creixell, Pau; van Vlimmeren, Anne; Joughin, Brian A; Miller, Chad J; Haide ... P30ES002109, R35ES028374 Elife (2019 05 24) 31124786 Exiting the NIEHS site 2019 
Pan-TAM Tyrosine Kinase Inhibitor BMS-777607 Enhances Anti-PD-1 mAb Efficacy in a Murine Model of Tr ...   Kasikara, Canan; Davra, Viralkumar; Calianese, David; Geng, Ke; Spires, Thomas E; Quigley, Mic ... R35ES028374 Cancer Res (2019 05 15) 30877108 Exiting the NIEHS site 2019 
ROS and Oxidative Stress Are Elevated in Mitosis during Asynchronous Cell Cycle Progression and Are ...   Patterson, Jesse C; Joughin, Brian A; van de Kooij, Bert; Lim, Daniel C; Lauffenburger, Douglas ... P30ES002109, R35ES028374 Cell Syst (2019 02 27) 30797774 Exiting the NIEHS site 2019 
Substrate-based kinase activity inference identifies MK2 as driver of colitis.   Strasser, Samantha Dale; Ghazi, Phaedra C; Starchenko, Alina; Boukhali, Myriam; Edwards, Amanda ... R35ES028374 Integr Biol (Camb) (2019 11 26) 31617572 Exiting the NIEHS site 2019 
VISAGE Reveals a Targetable Mitotic Spindle Vulnerability in Cancer Cells.   Patterson, Jesse C; Joughin, Brian A; Prota, Andrea E; Mühlethaler, Tobias; Jonas, Oliver H; Wh ... P30ES002109, R35ES028374 Cell Syst (2019 07 24) 31302152 Exiting the NIEHS site 2019 
Enhanced efficacy of combined temozolomide and bromodomain inhibitor therapy for gliomas using targe ...   Lam, Fred C; Morton, Stephen W; Wyckoff, Jeffrey; Vu Han, Tu-Lan; Hwang, Mun Kyung; Maffa, Ama ... R35ES028374 Nat Commun (2018 05 18) 29777137 Exiting the NIEHS site 2018 
Hierarchical Organization Endows the Kinase Domain with Regulatory Plasticity.   Creixell, Pau; Pandey, Jai P; Palmeri, Antonio; Bhattacharyya, Moitrayee; Creixell, Marc; Ranga ... R35ES028374 Cell Syst (2018 10 24) 30243563 Exiting the NIEHS site 2018 
Histidine N(τ)-cyclized macrocycles as a new genre of polo-like kinase 1 polo-box domain-binding inh ...   Hymel, David; Grant, Robert A; Tsuji, Kohei; Yaffe, Michael B; Burke Jr, Terrence R R35ES028374 Bioorg Med Chem Lett (2018 10 15) 30174151 Exiting the NIEHS site 2018 
MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis.   Suarez-Lopez, Lucia; Sriram, Ganapathy; Kong, Yi Wen; Morandell, Sandra; Merrick, Karl A; Herna ... R35ES028374 Proc Natl Acad Sci U S A (2018 05 01) 29666270 Exiting the NIEHS site 2018 
A Multivariate Computational Method to Analyze High-Content RNAi Screening Data.   Rameseder, Jonathan; Krismer, Konstantin; Dayma, Yogesh; Ehrenberger, Tobias; Hwang, Mun Kyung; ... P30ES002109, R35ES028374 J Biomol Screen (2015 Sep) 25918037 Exiting the NIEHS site 2015 
A Pleiotropic RNA-Binding Protein Controls Distinct Cell Cycle Checkpoints to Drive Resistance of p5 ...   Cannell, Ian G; Merrick, Karl A; Morandell, Sandra; Zhu, Chang-Qi; Braun, Christian J; Grant, ... P30ES002109, R35ES028374 Cancer Cell (2015 Nov 09) 26602816 Exiting the NIEHS site 2015 
Neighbor-directed histidine N (τ)-alkylation: A route to imidazolium-containing phosphopeptide macro ...   Qian, Wen-Jian; Park, Jung-Eun; Grant, Robert; Lai, Christopher C; Kelley, James A; Yaffe, Mic ... R35ES028374 Biopolymers (2015 Nov) 26152807 Exiting the NIEHS site 2015 
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