| Project Title: | PROTEIN KINASE SIGNALING IN THE GENOTOXIC STRESS RESPONSE |
|---|---|
| PI: | Yaffe, Michael B |
| Institution: | Massachusetts Institute Of Technology |
| Grant Number: | R35ES028374 |
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Viewing 18 publications
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| Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
|---|---|---|---|---|---|
| BRD4 prevents the accumulation of R-loops and protects against transcription-replication collision e ... | Lam, Fred C; Kong, Yi Wen; Huang, Qiuying; Vu Han, Tu-Lan; Maffa, Amanda D; Kasper, Ekkehard M ... | R35ES028374 | Nat Commun (2020 08 14) |
32796829
|
2020 |
| Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide exc ... | Kong, Yi Wen; Dreaden, Erik C; Morandell, Sandra; Zhou, Wen; Dhara, Sanjeev S; Sriram, Ganapat ... | R35ES028374 | Nat Commun (2020 08 17) |
32807787
|
2020 |
| Monitoring and modeling of lymphocytic leukemia cell bioenergetics reveals decreased ATP synthesis d ... | Kang, Joon Ho; Katsikis, Georgios; Li, Zhaoqi; Sapp, Kiera M; Stockslager, Max A; Lim, Daniel; ... | R35ES028374 | Nat Commun (2020 10 05) |
33020492
|
2020 |
| Redox priming promotes Aurora A activation during mitosis. | Lim, Daniel C; Joukov, Vladimir; Rettenmaier, T Justin; Kumagai, Akiko; Dunphy, William G; Well ... | R35ES028374 | Sci Signal (2020 07 21) |
32694171
|
2020 |
| Transite: A Computational Motif-Based Analysis Platform That Identifies RNA-Binding Proteins Modulat ... | Krismer, Konstantin; Bird, Molly A; Varmeh, Shohreh; Handly, Erika D; Gattinger, Anna; Bernwink ... | R35ES028374 | Cell Rep (2020 08 25) |
32846122
|
2020 |
| Comprehensive profiling of the STE20 kinase family defines features essential for selective substrat ... | Miller, Chad J; Lou, Hua Jane; Simpson, Craig; van de Kooij, Bert; Ha, Byung Hak; Fisher, Oria ... | R35ES028374 | PLoS Biol (2019 03) |
30897078
|
2019 |
| Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling o ... | van de Kooij, Bert; Creixell, Pau; van Vlimmeren, Anne; Joughin, Brian A; Miller, Chad J; Haide ... | P30ES002109, R35ES028374 | Elife (2019 05 24) |
31124786
|
2019 |
| Pan-TAM Tyrosine Kinase Inhibitor BMS-777607 Enhances Anti-PD-1 mAb Efficacy in a Murine Model of Tr ... | Kasikara, Canan; Davra, Viralkumar; Calianese, David; Geng, Ke; Spires, Thomas E; Quigley, Mic ... | R35ES028374 | Cancer Res (2019 05 15) |
30877108
|
2019 |
| ROS and Oxidative Stress Are Elevated in Mitosis during Asynchronous Cell Cycle Progression and Are ... | Patterson, Jesse C; Joughin, Brian A; van de Kooij, Bert; Lim, Daniel C; Lauffenburger, Douglas ... | P30ES002109, R35ES028374 | Cell Syst (2019 02 27) |
30797774
|
2019 |
| Substrate-based kinase activity inference identifies MK2 as driver of colitis. | Strasser, Samantha Dale; Ghazi, Phaedra C; Starchenko, Alina; Boukhali, Myriam; Edwards, Amanda ... | R35ES028374 | Integr Biol (Camb) (2019 11 26) |
31617572
|
2019 |
| VISAGE Reveals a Targetable Mitotic Spindle Vulnerability in Cancer Cells. | Patterson, Jesse C; Joughin, Brian A; Prota, Andrea E; Mühlethaler, Tobias; Jonas, Oliver H; Wh ... | P30ES002109, R35ES028374 | Cell Syst (2019 07 24) |
31302152
|
2019 |
| Enhanced efficacy of combined temozolomide and bromodomain inhibitor therapy for gliomas using targe ... | Lam, Fred C; Morton, Stephen W; Wyckoff, Jeffrey; Vu Han, Tu-Lan; Hwang, Mun Kyung; Maffa, Ama ... | R35ES028374 | Nat Commun (2018 05 18) |
29777137
|
2018 |
| Hierarchical Organization Endows the Kinase Domain with Regulatory Plasticity. | Creixell, Pau; Pandey, Jai P; Palmeri, Antonio; Bhattacharyya, Moitrayee; Creixell, Marc; Ranga ... | R35ES028374 | Cell Syst (2018 10 24) |
30243563
|
2018 |
| Histidine N(τ)-cyclized macrocycles as a new genre of polo-like kinase 1 polo-box domain-binding inh ... | Hymel, David; Grant, Robert A; Tsuji, Kohei; Yaffe, Michael B; Burke Jr, Terrence R | R35ES028374 | Bioorg Med Chem Lett (2018 10 15) |
30174151
|
2018 |
| MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis. | Suarez-Lopez, Lucia; Sriram, Ganapathy; Kong, Yi Wen; Morandell, Sandra; Merrick, Karl A; Herna ... | R35ES028374 | Proc Natl Acad Sci U S A (2018 05 01) |
29666270
|
2018 |
| A Multivariate Computational Method to Analyze High-Content RNAi Screening Data. | Rameseder, Jonathan; Krismer, Konstantin; Dayma, Yogesh; Ehrenberger, Tobias; Hwang, Mun Kyung; ... | P30ES002109, R35ES028374 | J Biomol Screen (2015 Sep) |
25918037
|
2015 |
| A Pleiotropic RNA-Binding Protein Controls Distinct Cell Cycle Checkpoints to Drive Resistance of p5 ... | Cannell, Ian G; Merrick, Karl A; Morandell, Sandra; Zhu, Chang-Qi; Braun, Christian J; Grant, ... | P30ES002109, R35ES028374 | Cancer Cell (2015 Nov 09) |
26602816
|
2015 |
| Neighbor-directed histidine N (τ)-alkylation: A route to imidazolium-containing phosphopeptide macro ... | Qian, Wen-Jian; Park, Jung-Eun; Grant, Robert; Lai, Christopher C; Kelley, James A; Yaffe, Mic ... | R35ES028374 | Biopolymers (2015 Nov) |
26152807
|
2015 |