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Your Environment. Your Health.

Who We Fund: Publication Detail

Project Title: BIOACTIVE LIPIDS AS EFFECTORS AND INDICATORS OF THE DELETERIOUS EFFECTS OF ENVIRONMENTAL EXPOSURE ON CHRONIC DISEASES
PI: Hammock, Bruce D
Institution: University Of California At Davis
Grant Number: R35ES030443

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 58 publications
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Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Carcinogenesis: Failure of resolution of inflammation?   Fishbein, Anna; Hammock, Bruce D; Serhan, Charles N; Panigrahy, Dipak R35ES030443 Pharmacol Ther (2021 Feb) 32891711 Exiting the NIEHS site 2021 
Development of a nanobody-based ELISA for the detection of the insecticides cyantraniliprole and chl ...   Xu, Bojie; Wang, Kai; Vasylieva, Natalia; Zhou, Hang; Xue, Xianle; Wang, Baomin; Li, Qing X; ... P42ES004699, R35ES030443 Anal Bioanal Chem (2021 Feb 13) 33580830 Exiting the NIEHS site 2021 
Discovery of Soluble Epoxide Hydrolase Inhibitors from Chemical Synthesis and Natural Products.   Sun, Cheng-Peng; Zhang, Xin-Yue; Morisseau, Christophe; Hwang, Sung Hee; Zhang, Zhan-Jun; Hammo ... P42ES004699, R35ES030443 J Med Chem (2021 01 14) 33369424 Exiting the NIEHS site 2021 
Highly specific nanobody against herbicide 2,4-dichlorophenoxyacetic acid for monitoring of its cont ...   Li, Zhen-Feng; Dong, Jie-Xian; Vasylieva, Natalia; Cui, Yong-Liang; Wan, De-Bin; Hua, Xiu-De; ... P42ES004699, R35ES030443 Sci Total Environ (2021 Jan 20) 32906044 Exiting the NIEHS site 2021 
Identification of the Functional Binding Site for the Convulsant Tetramethylenedisulfotetramine in t ...   Pressly, Brandon; Lee, Ruth D; Barnych, Bogdan; Hammock, Bruce D; Wulff, Heike R35ES030443 Mol Pharmacol (2021 01) 33109687 Exiting the NIEHS site 2021 
Inhibition of the Soluble Epoxide Hydrolase as an Analgesic Strategy: A Review of Preclinical Eviden ...   Wang, Yuxin; Wagner, Karen M; Morisseau, Christophe; Hammock, Bruce D R35ES030443 J Pain Res (2021) 33488116 Exiting the NIEHS site 2021 
Preservation of epoxyeicosatrienoic acid bioavailability prevents renal allograft dysfunction and ca ...   Duflot, Thomas; Laurent, Charlotte; Soudey, Anne; Fonrose, Xavier; Hamzaoui, Mouad; Iacob, Mic ... P42ES004699, R35ES030443 Sci Rep (2021 Feb 12) 33580125 Exiting the NIEHS site 2021 
Soluble Epoxide Hydrolase in Aged Female Mice and Human Explanted Hearts Following Ischemic Injury.   Jamieson, K Lockhart; Darwesh, Ahmed M; Sosnowski, Deanna K; Zhang, Hao; Shah, Saumya; Zhabyeye ... P42ES004699, R35ES030443 Int J Mol Sci (2021 Feb 08) 33567578 Exiting the NIEHS site 2021 
2-Oxaadamant-1-yl Ureas as Soluble Epoxide Hydrolase Inhibitors: In Vivo Evaluation in a Murine Mode ...   Codony, Sandra; Pujol, Eugènia; Pizarro, Javier; Feixas, Ferran; Valverde, Elena; Loza, M Isab ... P42ES004699, R35ES030443 J Med Chem (2020 09 10) 32787085 Exiting the NIEHS site 2020 
A facile, sensitive and rapid sensing platform based on CoZnO for detection of fipronil; an environm ...   Kumar, Sanni; Vasylieva, Natalia; Singh, Vikrant; Hammock, Bruce; Singh, Shiv Govind P42ES004699, R35ES030443 Electroanalysis (2020 Sep) 33456276 Exiting the NIEHS site 2020 
A rapid and simple fluorescence enzyme-linked immunosorbent assay for tetrabromobisphenol A in soil ...   Fu, Hui-Jun; Wang, Yu; Xiao, Zhi-Li; Wang, Hong; Li, Zhen-Feng; Shen, Yu-Dong; Lei, Hong-Tao; ... P42ES004699, R35ES030443 Ecotoxicol Environ Saf (2020 Jan 30) 31704326 Exiting the NIEHS site 2020 
An epoxide hydrolase inhibitor reduces neuroinflammation in a mouse model of Alzheimer's disease.   Ghosh, Anamitra; Comerota, Michele M; Wan, Debin; Chen, Fading; Propson, Nicholas E; Hwang, Su ... P42ES004699, R35ES030443 Sci Transl Med (2020 12 09) 33298560 Exiting the NIEHS site 2020 
An Ultrasensitive Bioluminescent Enzyme Immunoassay Based on Nanobody/Nanoluciferase Heptamer Fusion ...   Li, Zhenfeng; Wang, Yi; Vasylieva, Natalia; Wan, Debin; Yin, Zihan; Dong, Jiexian; Hammock, B ... P42ES004699, R35ES030443 Anal Chem (2020 07 21) 32559059 Exiting the NIEHS site 2020 
Aryl Hydrocarbon Receptor-Dependent inductions of omega-3 and omega-6 polyunsaturated fatty acid met ...   Huerta-Yepez, Sara; Tirado-Rodriguez, Ana; Montecillo-Aguado, Mayra R; Yang, Jun; Hammock, Bruc ... P42ES004699, R35ES030443 Sci Rep (2020 05 12) 32398692 Exiting the NIEHS site 2020 
Assessment of soluble epoxide hydrolase activity in vivo: A metabolomic approach.   Stefanovski, Darko; Shih, Pei-An Betty; Hammock, Bruce D; Watanabe, Richard M; Youn, Jang H P42ES004699, R35ES030443 Prostaglandins Other Lipid Mediat (2020 06) 31931080 Exiting the NIEHS site 2020 
Bioisosteric substitution of adamantane with bicyclic lipophilic groups improves water solubility of ...   Burmistrov, Vladimir; Morisseau, Christophe; Karlov, Dmitry; Pitushkin, Dmitry; Vernigora, Andr ... P42ES004699, R35ES030443 Bioorg Med Chem Lett (2020 09 15) 32736212 Exiting the NIEHS site 2020 
Chemiluminescent Enzyme Immunoassay and Bioluminescent Enzyme Immunoassay for Tenuazonic Acid Mycoto ...   Wang, Feng; Li, Zhen-Feng; Yang, Yuan-Yuan; Wan, De-Bin; Vasylieva, Natalia; Zhang, Yu-Qi; Cai ... P42ES004699, R35ES030443 Anal Chem (2020 09 01) 32702970 Exiting the NIEHS site 2020 
Comparison of the toxicokinetics of the convulsants picrotoxinin and tetramethylenedisulfotetramine ...   Pressly, Brandon; Vasylieva, Natalia; Barnych, Bogdan; Singh, Vikrant; Singh, Latika; Bruun, D ... R35ES030443 Arch Toxicol (2020 06) 32239239 Exiting the NIEHS site 2020 
Cytochrome P450-derived linoleic acid metabolites EpOMEs and DiHOMEs: a review of recent studies.   Hildreth, Kelsey; Kodani, Sean D; Hammock, Bruce D; Zhao, Ling P42ES004699, R35ES030443 J Nutr Biochem (2020 12) 32827665 Exiting the NIEHS site 2020 
Development of a Highly Sensitive Enzyme-Linked Immunosorbent Assay for Mouse Soluble Epoxide Hydrol ...   Li, Dongyang; Cui, Yongliang; Morisseau, Christophe; Wagner, Karen M; Cho, Young Sik; Hammock, ... P42ES004699, R35ES030443 Anal Chem (2020 09 01) 32786492 Exiting the NIEHS site 2020 
Development of Improved Double-Nanobody Sandwich ELISAs for Human Soluble Epoxide Hydrolase Detectio ...   Li, Dongyang; Morisseau, Christophe; McReynolds, Cindy B; Duflot, Thomas; Bellien, Jérémy; Nagr ... P42ES004699, R35ES030443 Anal Chem (2020 05 19) 32253910 Exiting the NIEHS site 2020 
Development of multitarget inhibitors for the treatment of pain: Design, synthesis, biological evalu ...   Wilt, Stephanie; Kodani, Sean; Le, Thanh N H; Nguyen, Lato; Vo, Nghi; Ly, Tanya; Rodriguez, M ... P42ES004699, R35ES030443 Bioorg Chem (2020 10) 32891856 Exiting the NIEHS site 2020 
Development of potent inhibitors of the human microsomal epoxide hydrolase.   Barnych, Bogdan; Singh, Nalin; Negrel, Sophie; Zhang, Yue; Magis, Damien; Roux, Capucine; Hua, ... P42ES004699, R35ES030443 Eur J Med Chem (2020 May 01) 32203787 Exiting the NIEHS site 2020 
Early antihypertensive treatment and ischemia-induced acute kidney injury.   Greite, Robert; Derlin, Katja; Hensen, Bennet; Thorenz, Anja; Rong, Song; Chen, Rongjun; Hellm ... R35ES030443 Am J Physiol Renal Physiol (2020 10 01) 32799675 Exiting the NIEHS site 2020 
Editorial: Clinical Paths for Soluble Epoxide Hydrolase Inhibitors.   Imig, John D; Morisseau, Christophe R35ES030443 Front Pharmacol (2020) 33071800 Exiting the NIEHS site 2020 
Eicosanoids: The Overlooked Storm in Coronavirus Disease 2019 (COVID-19)?   Hammock, Bruce D; Wang, Weicang; Gilligan, Molly M; Panigrahy, Dipak P42ES004699, R35ES030443 Am J Pathol (2020 09) 32650004 Exiting the NIEHS site 2020 
EpOMEs act as immune suppressors in a lepidopteran insect, Spodoptera exigua.   Vatanparast, Mohammad; Ahmed, Shabbir; Lee, Dong-Hee; Hwang, Sung Hee; Hammock, Bruce; Kim, Yo ... R35ES030443 Sci Rep (2020 11 19) 33214688 Exiting the NIEHS site 2020 
Epoxy Fatty Acids Are Promising Targets for Treatment of Pain, Cardiovascular Disease and Other Indi ...   McReynolds, Cindy; Morisseau, Christophe; Wagner, Karen; Hammock, Bruce P42ES004699, R35ES030443 Adv Exp Med Biol (2020) 32894508 Exiting the NIEHS site 2020 
Imidazolidine-2,4,5- and pirimidine-2,4,6-triones - New primary pharmacophore for soluble epoxide hy ...   Burmistrov, Vladimir; Morisseau, Christophe; D'yachenko, Vladimir; Karlov, Dmitry; Butov, Genna ... P42ES004699, R35ES030443 Bioorg Med Chem Lett (2020 02 01) 31870649 Exiting the NIEHS site 2020 
Increased expression of soluble epoxide hydrolase in the brain and liver from patients with major ps ...   Zhang, Jiancheng; Tan, Yunfei; Chang, Lijia; Hammock, Bruce D; Hashimoto, Kenji P42ES004699, R35ES030443 J Affect Disord (2020 06 01) 32339103 Exiting the NIEHS site 2020 
Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19?   Panigrahy, Dipak; Gilligan, Molly M; Huang, Sui; Gartung, Allison; Cortés-Puch, Irene; Sime, P ... P42ES004699, R35ES030443 Cancer Metastasis Rev (2020 06) 32385712 Exiting the NIEHS site 2020 
Macromolecular modeling and design in Rosetta: recent methods and frameworks.   Leman, Julia Koehler; Weitzner, Brian D; Lewis, Steven M; Adolf-Bryfogle, Jared; Alam, Nawsad; ... P42ES004699, R35ES030443 Nat Methods (2020 07) 32483333 Exiting the NIEHS site 2020 
Maternal glyphosate exposure causes autism-like behaviors in offspring through increased expression ...   Pu, Yaoyu; Yang, Jun; Chang, Lijia; Qu, Youge; Wang, Siming; Zhang, Kai; Xiong, Zhongwei; Zha ... P42ES004699, R35ES030443 Proc Natl Acad Sci U S A (2020 05 26) 32398374 Exiting the NIEHS site 2020 
N-Benzyl-linoleamide, a Constituent of Lepidium meyenii (Maca), Is an Orally Bioavailable Soluble Ep ...   Singh, Nalin; Barnych, Bogdan; Morisseau, Christophe; Wagner, Karen M; Wan, Debin; Takeshita, ... P42ES004699, R35ES030443 J Nat Prod (2020 12 24) 33320645 Exiting the NIEHS site 2020 
Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer's Disease.   Griñán-Ferré, Christian; Codony, Sandra; Pujol, Eugènia; Yang, Jun; Leiva, Rosana; Escolano, C ... P42ES004699, R35ES030443 Neurotherapeutics (2020 10) 32488482 Exiting the NIEHS site 2020 
Production of a specific monoclonal antibody for 1-naphthol based on novel hapten strategy and devel ...   Chen, Zi-Jian; Liu, Xi-Xia; Xiao, Zhi-Li; Fu, Hui-Jun; Huang, Yu-Ping; Huang, Shu-Yi; Shen, Y ... P42ES004699, R35ES030443 Ecotoxicol Environ Saf (2020 Jun 15) 32247241 Exiting the NIEHS site 2020 
Protostane-type triterpenoids as natural soluble epoxide hydrolase inhibitors: Inhibition potentials ...   Sun, Cheng-Peng; Zhang, Juan; Zhao, Wen-Yu; Yi, Jing; Yan, Jian-Kun; Wang, Ya-Li; Morisseau, ... P42ES004699, R35ES030443 Bioorg Chem (2020 03) 32032849 Exiting the NIEHS site 2020 
Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellula ...   Fishbein, Anna; Wang, Weicang; Yang, Haixia; Yang, Jun; Hallisey, Victoria M; Deng, Jianjun; V ... P42ES004699, R35ES030443 Proc Natl Acad Sci U S A (2020 09 01) 32801214 Exiting the NIEHS site 2020 
Selection of Potent Inhibitors of Soluble Epoxide Hydrolase for Usage in Veterinary Medicine.   Shihadih, Diyala S; Harris, Todd R; Kodani, Sean D; Hwang, Sung-Hee; Lee, Kin Sing Stephen; Mav ... P42ES004699, R35ES030443 Front Vet Sci (2020) 33005645 Exiting the NIEHS site 2020 
Sensitive Immunochromatographic Assay Using Highly Luminescent Quantum Dot Nanobeads as Tracer for t ...   Li, Pan; Yang, Cuifeng; Liu, Beibei; Wu, Qin; Wang, Yulong; Dong, Sa; Zhang, Hanxiaoya; Vasyl ... P42ES004699, R35ES030443 Front Chem (2020) 32760698 Exiting the NIEHS site 2020 
Simultaneous Target-Mediated Drug Disposition Model for Two Small-Molecule Compounds Competing for T ...   Wu, Nan; Hammock, Bruce D; Lee, Kin Sing Stephen; An, Guohua P42ES004699, R35ES030443 J Pharmacol Exp Ther (2020 07) 32238455 Exiting the NIEHS site 2020 
Soluble Epoxide Hydrolase Hepatic Deficiency Ameliorates Alcohol-Associated Liver Disease.   Mello, Aline; Hsu, Ming-Fo; Koike, Shinichiro; Chu, Bryan; Cheng, Jeff; Yang, Jun; Morisseau, ... P42ES004699, R35ES030443 Cell Mol Gastroenterol Hepatol (2020 Oct 15) 33068774 Exiting the NIEHS site 2020 
Soluble epoxide hydrolase inhibition improves cognitive function and parenchymal artery dilation in ...   Matin, Nusrat; Fisher, Courtney; Lansdell, Theresa A; Hammock, Bruce D; Yang, Jun; Jackson, Wi ... P42ES004699, R35ES030443 Microcirculation (2020 Aug 07) 32767848 Exiting the NIEHS site 2020 
Soluble epoxide hydrolase inhibitor, TPPU, increases regulatory T cells pathway in an arthritis mode ...   Trindade-da-Silva, Carlos A; Clemente-Napimoga, Juliana T; Abdalla, Henrique B; Rosa, Sergio Mar ... P42ES004699, R35ES030443 FASEB J (2020 07) 32400048 Exiting the NIEHS site 2020 
Soluble epoxide hydrolase is an endogenous regulator of obesity-induced intestinal barrier dysfuncti ...   Wang, Yuxin; Yang, Jun; Wang, Weicang; Sanidad, Katherine Z; Cinelli, Maris A; Wan, Debin; Hwa ... P42ES004699, R35ES030443 Proc Natl Acad Sci U S A (2020 04 14) 32220957 Exiting the NIEHS site 2020 
Soluble Epoxide Hydrolase Regulation of Lipid Mediators Limits Pain.   Wagner, Karen M; Gomes, Aldrin; McReynolds, Cindy B; Hammock, Bruce D P42ES004699, R35ES030443 Neurotherapeutics (2020 07) 32875445 Exiting the NIEHS site 2020 
Suppression of inflammation and fibrosis using soluble epoxide hydrolase inhibitors enhances cardiac ...   Sirish, Padmini; Thai, Phung N; Lee, Jeong Han; Yang, Jun; Zhang, Xiao-Dong; Ren, Lu; Li, Nin ... P42ES004699, R35ES030443 Stem Cells Transl Med (2020 12) 32790136 Exiting the NIEHS site 2020 
Target-Mediated Drug Disposition-A Class Effect of Soluble Epoxide Hydrolase Inhibitors.   An, Guohua; Lee, Kin Sing Stephen; Yang, Jun; Hammock, Bruce D R35ES030443 J Clin Pharmacol (2020 Oct 19) 33078430 Exiting the NIEHS site 2020 
Using sulfuramidimidoyl fluorides that undergo sulfur(VI) fluoride exchange for inverse drug discove ...   Brighty, Gabriel J; Botham, Rachel C; Li, Suhua; Nelson, Luke; Mortenson, David E; Li, Genchen ... P42ES004699, R35ES030443 Nat Chem (2020 10) 32868886 Exiting the NIEHS site 2020 
Vascular Lipidomic Profiling of Potential Endogenous Fatty Acid PPAR Ligands Reveals the Coronary Ar ...   Edin, Matthew L; Lih, Fred B; Hammock, Bruce D; Thomson, Scott; Zeldin, Darryl C; Bishop-Bailey ... P42ES004699, R35ES030443 Cells (2020 04 29) 32365470 Exiting the NIEHS site 2020 
Vitamin D deficiency serves as a precursor to stunted growth and central adiposity in zebrafish.   Knuth, Megan M; Mahapatra, Debabrata; Jima, Dereje; Wan, Debin; Hammock, Bruce D; Law, Mac; Ku ... P30ES025128, P42ES004699, R35ES030443, T32ES007046 Sci Rep (2020 09 29) 32994480 Exiting the NIEHS site 2020 
ω-3 Polyunsaturated Fatty Acids on Colonic Inflammation and Colon Cancer: Roles of Lipid-Metabolizin ...   Tu, Maolin; Wang, Weicang; Zhang, Guodong; Hammock, Bruce D P42ES004699, R35ES030443 Nutrients (2020 Oct 28) 33126566 Exiting the NIEHS site 2020 
1-Trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea, a Selective and Potent Dual Inhibitor o ...   Liang, Zhibin; Zhang, Bei; Xu, Meng; Morisseau, Christophe; Hwang, Sung Hee; Hammock, Bruce D; ... P42ES004699, R35ES030443 ACS Chem Neurosci (2019 09 18) 31378059 Exiting the NIEHS site 2019 
Anti-inflammatory treatment with a soluble epoxide hydrolase inhibitor attenuates seizures and epile ...   Shen, Yijun; Peng, Weifeng; Chen, Qinglan; Hammock, Bruce D; Liu, Junyan; Li, Dongyang; Yang, ... P42ES004699, R35ES030443 Brain Behav Immun (2019 10) 31306773 Exiting the NIEHS site 2019 
Drug-Target Residence Time Affects in Vivo Target Occupancy through Multiple Pathways.   Lee, Kin Sing Stephen; Yang, Jun; Niu, Jun; Ng, Connie J; Wagner, Karen M; Dong, Hua; Kodani, ... R35ES030443 ACS Cent Sci (2019 Sep 25) 31572788 Exiting the NIEHS site 2019 
Effect Of Dual sEH/COX-2 Inhibition on Allergen-Induced Airway Inflammation.   Dileepan, Mythili; Rastle-Simpson, Stephanie; Greenberg, Yana; Wijesinghe, Dayanjan S; Kumar, N ... R35ES030443 Front Pharmacol (2019) 31611798 Exiting the NIEHS site 2019 
Epoxyeicosatrienoic acid (EET)-stimulated angiogenesis is mediated by epoxy hydroxyeicosatrienoic ac ...   Rand, Amy A; Rajamani, Anita; Kodani, Sean D; Harris, Todd R; Schlatt, Lukas; Barnych, Bodgan; ... P42ES004699, R35ES030443 J Lipid Res (2019 12) 31641036 Exiting the NIEHS site 2019 
Modulating Linker Composition of Haptens Resulted in Improved Immunoassay for Histamine.   Luo, Lin; Wei, Xiao-Qun; Jia, Bao-Zhu; Yang, Jin-Yi; Shen, Yu-Dong; Hammock, Bruce; Dong, Jie ... P42ES004699, R35ES030443 Biomolecules (2019 10 11) 31614550 Exiting the NIEHS site 2019 
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