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Your Environment. Your Health.

Who We Fund: Publication Detail

Project Title: TRAINING PROGRAM IN ENVIRONMENTAL TOXICOLOGY
PI: Guengerich, F Peter
Institution: Vanderbilt University
Grant Number: T32ES007028

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 344 publications
Export to Excel (http://www.niehs.nih.gov//portfolio/index.cfm/portfolio/grantpubdetail/grant_number/T32ES007028/format/excel)
Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Mfd regulates RNA polymerase association with hard-to-transcribe regions in vivo, especially those w ...   Ragheb, Mark N; Merrikh, Christopher; Browning, Kaitlyn; Merrikh, Houra T32ES007028 Proc Natl Acad Sci U S A (2021 Jan 05) 33443179 Exiting the NIEHS site 2021 
A Small-Molecule Modulator of Metal Homeostasis in Gram-Positive Pathogens.   Juttukonda, Lillian J; Beavers, William N; Unsihuay, Daisy; Kim, Kwangho; Pishchany, Gleb; Horn ... R01ES010563, T32ES007028 mBio (2020 10 27) 33109764 Exiting the NIEHS site 2020 
Bacillus anthracis Responds to Targocil-Induced Envelope Damage through EdsRS Activation of Cardioli ...   Laut, Clare L; Perry, William J; Metzger, Alexander L; Weiss, Andy; Stauff, Devin L; Walker, S ... T32ES007028 mBio (2020 03 31) 32234818 Exiting the NIEHS site 2020 
Developmental 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure of either parent enhances the risk of nec ...   Mokshagundam, Shilpa; Ding, Tianbing; Rumph, Jelonia T; Dallas, Madison; Stephens, Victoria R; ... T32ES007028 Birth Defects Res (2020 10) 32519502 Exiting the NIEHS site 2020 
Escherichia coli YcaQ is a DNA glycosylase that unhooks DNA interstrand crosslinks.   Bradley, Noah P; Washburn, Lauren A; Christov, Plamen P; Watanabe, Coran M H; Eichman, Brandt F T32ES007028 Nucleic Acids Res (2020 07 27) 32409837 Exiting the NIEHS site 2020 
Functional interactions of adrenodoxin with several human mitochondrial cytochrome P450 enzymes.   Child, Stella A; Reddish, Michael J; Glass, Sarah M; Goldfarb, Margo H; Barckhausen, Ian R; Gue ... T32ES007028 Arch Biochem Biophys (2020 11 15) 32980349 Exiting the NIEHS site 2020 
Huntington's disease genotype suppresses global manganese-responsive processes in pre-manifest and m ...   Pfalzer, Anna C; Wilcox, Jordyn M; Codreanu, Simona G; Totten, Melissa; Bichell, Terry J V; Hal ... R01ES010563, T32ES007028 Metallomics (2020 07 22) 32421118 Exiting the NIEHS site 2020 
Identification of a selective manganese ionophore that enables nonlethal quantification of cellular ...   Horning, Kyle J; Joshi, Piyush; Nitin, Rachana; Balachandran, Rekha C; Yanko, Frank M; Kim, Kw ... R01ES010563, T32ES007028 J Biol Chem (2020 03 20) 32047113 Exiting the NIEHS site 2020 
Integrating ion mobility and imaging mass spectrometry for comprehensive analysis of biological tiss ...   Rivera, Emilio S; Djambazova, Katerina V; Neumann, Elizabeth K; Caprioli, Richard M; Spraggins, ... T32ES007028 J Mass Spectrom (2020 Dec) 32955134 Exiting the NIEHS site 2020 
Manganese Acts upon Insulin/IGF Receptors to Phosphorylate AKT and Increase Glucose Uptake in Huntin ...   Bryan, Miles R; Nordham, Kristen D; Rose, Daniel I R; O'Brien, Michael T; Joshi, Piyush; Foshag ... R01ES010563, T32ES007028 Mol Neurobiol (2020 Mar) 31797328 Exiting the NIEHS site 2020 
Resolving the Complexity of Spatial Lipidomics Using MALDI TIMS Imaging Mass Spectrometry.   Djambazova, Katerina V; Klein, Dustin R; Migas, Lukasz G; Neumann, Elizabeth K; Rivera, Emilio ... T32ES007028 Anal Chem (2020 10 06) 32808523 Exiting the NIEHS site 2020 
A Simplified, Fully Defined Differentiation Scheme for Producing Blood-Brain Barrier Endothelial Cel ...   Neal, Emma H; Marinelli, Nicholas A; Shi, Yajuan; McClatchey, P Mason; Balotin, Kylie M; Gullet ... T32ES007028 Stem Cell Reports (2019 06 11) 31189096 Exiting the NIEHS site 2019 
Acute manganese treatment restores defective autophagic cargo loading in Huntington's disease cell l ...   Bryan, Miles R; O'Brien, Michael T; Nordham, Kristen D; Rose, Daniel I R; Foshage, Audra M; Jos ... R01ES010563, T32ES007028 Hum Mol Genet (2019 11 15) 31600787 Exiting the NIEHS site 2019 
Common motifs in ETAA1 and TOPBP1 required for ATR kinase activation.   Thada, Vaughn; Cortez, David T32ES007028 J Biol Chem (2019 05 24) 30940728 Exiting the NIEHS site 2019 
Conformational selection dominates binding of steroids to human cytochrome P450 17A1.   Guengerich, F Peter; Wilkey, Clayton J; Glass, Sarah M; Reddish, Michael J T32ES007028 J Biol Chem (2019 06 28) 31072872 Exiting the NIEHS site 2019 
Emerging Roles of DNA Glycosylases and the Base Excision Repair Pathway.   Mullins, Elwood A; Rodriguez, Alyssa A; Bradley, Noah P; Eichman, Brandt F T32ES007028 Trends Biochem Sci (2019 09) 31078398 Exiting the NIEHS site 2019 
Extensive loss of cell-cycle and DNA repair genes in an ancient lineage of bipolar budding yeasts.   Steenwyk, Jacob L; Opulente, Dana A; Kominek, Jacek; Shen, Xing-Xing; Zhou, Xiaofan; Labella, ... T32ES007028 PLoS Biol (2019 05) 31112549 Exiting the NIEHS site 2019 
Glutamine-451 Confers Sensitivity to Oxidative Inhibition and Heme-Thiolate Sulfenylation of Cytochr ...   Albertolle, Matthew E; Song, Hyun D; Wilkey, Clayton J; Segrest, Jere P; Guengerich, F Peter T32ES007028 Chem Res Toxicol (2019 03 18) 30701961 Exiting the NIEHS site 2019 
High-Performance Molecular Imaging with MALDI Trapped Ion-Mobility Time-of-Flight (timsTOF) Mass Spe ...   Spraggins, Jeffrey M; Djambazova, Katerina V; Rivera, Emilio S; Migas, Lukasz G; Neumann, Eliza ... T32ES007028 Anal Chem (2019 11 19) 31593446 Exiting the NIEHS site 2019 
Human cytochrome P450 11B2 produces aldosterone by a processive mechanism due to the lactol form of ...   Reddish, Michael J; Guengerich, F Peter T32ES007028 J Biol Chem (2019 08 30) 31296661 Exiting the NIEHS site 2019 
Isotopic tagging of oxidized and reduced cysteines (iTORC) for detecting and quantifying sulfenic ac ...   Albertolle, Matthew E; Glass, Sarah M; Trefts, Elijah; Guengerich, F Peter T32ES007028 J Biol Chem (2019 04 19) 30850396 Exiting the NIEHS site 2019 
Lysophospholipases cooperate to mediate lipid homeostasis and lysophospholipid signaling.   Wepy, James A; Galligan, James J; Kingsley, Philip J; Xu, Shu; Goodman, Michael C; Tallman, Ke ... T32ES007028 J Lipid Res (2019 02) 30482805 Exiting the NIEHS site 2019 
Nutrient Zinc at the Host-Pathogen Interface.   Lonergan, Zachery R; Skaar, Eric P T32ES007028 Trends Biochem Sci (2019 12) 31326221 Exiting the NIEHS site 2019 
Remodeling of mitochondrial morphology and function: an emerging hallmark of cellular reprogramming.   Rastogi, Anuj; Joshi, Piyush; Contreras, Ela; Gama, Vivian T32ES007028 Cell Stress (2019 May 27) 31225513 Exiting the NIEHS site 2019 
Striatal Cholesterol Precursors Are Altered with Age in Female Huntington's Disease Model Mice.   Pfalzer, Anna C; Wages, Phillip A; Porter, Ned A; Bowman, Aaron B T32ES007028 J Huntingtons Dis (2019) 30958310 Exiting the NIEHS site 2019 
Synthesis and Characterization of Site-Specific O6 -Alkylguanine DNA-Alkyl Transferase-Oligonucleoti ...   Ghodke, Pratibha P; Albertolle, Matthew E; Johnson, Kevin M; Guengerich, F Peter R01ES010546, R01ES026955, T32ES007028 Curr Protoc Nucleic Acid Chem (2019 03) 30657645 Exiting the NIEHS site 2019 
The abundant DNA adduct N7-methyl deoxyguanosine contributes to miscoding during replication by huma ...   Njuma, Olive J; Su, Yan; Guengerich, F Peter R01ES010546, T32ES007028 J Biol Chem (2019 06 28) 31101656 Exiting the NIEHS site 2019 
Configurational and Conformational Equilibria of N6-(2-Deoxy-d-erythro-pentofuranosyl)-2,6-diamino-3 ...   Bamberger, Stephanie N; Malik, Chanchal K; Voehler, Markus W; Brown, Summer K; Pan, Hope; Johns ... R01ES029357, T32ES007028 Chem Res Toxicol (2018 09 17) 30169026 Exiting the NIEHS site 2018 
Inherent steroid 17α,20-lyase activity in defunct cytochrome P450 17A enzymes.   Gonzalez, Eric; Johnson, Kevin M; Pallan, Pradeep S; Phan, Thanh T N; Zhang, Wei; Lei, Li; Waw ... T32ES007028 J Biol Chem (2018 01 12) 29212707 Exiting the NIEHS site 2018 
Movement of the RecG Motor Domain upon DNA Binding Is Required for Efficient Fork Reversal.   Warren, Garrett M; Stein, Richard A; Mchaourab, Hassane S; Eichman, Brandt F T32ES007028 Int J Mol Sci (2018 Oct 06) 30301235 Exiting the NIEHS site 2018 
Role of Calprotectin in Withholding Zinc and Copper from Candida albicans.   Besold, Angelique N; Gilston, Benjamin A; Radin, Jana N; Ramsoomair, Christian; Culbertson, Edw ... T32ES007028, T32ES007141 Infect Immun (2018 02) 29133349 Exiting the NIEHS site 2018 
Selective base excision repair of DNA damage by the non-base-flipping DNA glycosylase AlkC.   Shi, Rongxin; Mullins, Elwood A; Shen, Xing-Xing; Lay, Kori T; Yuen, Philip K; David, Sheila S ... T32ES007028 EMBO J (2018 01 04) 29054852 Exiting the NIEHS site 2018 
Sulfenylation of Human Liver and Kidney Microsomal Cytochromes P450 and Other Drug-Metabolizing Enzy ...   Albertolle, Matthew E; Phan, Thanh T N; Pozzi, Ambra; Guengerich, F Peter T32ES007028 Mol Cell Proteomics (2018 05) 29374135 Exiting the NIEHS site 2018 
The relationships between cytochromes P450 and H2O2: Production, reaction, and inhibition.   Albertolle, Matthew E; Peter Guengerich, F T32ES007028 J Inorg Biochem (2018 09) 29990746 Exiting the NIEHS site 2018 
Absolute Quantification of Rifampicin by MALDI Imaging Mass Spectrometry Using Multiple TOF/TOF Even ...   Prentice, Boone M; Chumbley, Chad W; Caprioli, Richard M T32ES007028 J Am Soc Mass Spectrom (2017 01) 27655354 Exiting the NIEHS site 2017 
Antibacterial photosensitization through activation of coproporphyrinogen oxidase.   Surdel, Matthew C; Horvath Jr, Dennis J; Lojek, Lisa J; Fullen, Audra R; Simpson, Jocelyn; Dutt ... T32ES007028 Proc Natl Acad Sci U S A (2017 08 08) 28739897 Exiting the NIEHS site 2017 
Compartmentalized Culture of Perivascular Stroma and Endothelial Cells in a Microfluidic Model of th ...   Gnecco, Juan S; Pensabene, Virginia; Li, David J; Ding, Tianbing; Hui, Elliot E; Bruner-Tran, ... T32ES007028 Ann Biomed Eng (2017 Jul) 28108942 Exiting the NIEHS site 2017 
Detecting Protein Sulfenylation in Cells Exposed to a Toxicant.   Wages, Phillip A R01ES007331, T32ES007028 Curr Protoc Toxicol (2017 Feb 01) 28146279 Exiting the NIEHS site 2017 
Dietary Manganese Promotes Staphylococcal Infection of the Heart.   Juttukonda, Lillian J; Berends, Evelien T M; Zackular, Joseph P; Moore, Jessica L; Stier, Matth ... T32ES007028 Cell Host Microbe (2017 Oct 11) 28943329 Exiting the NIEHS site 2017 
Exposure to the environmental endocrine disruptor TCDD and human reproductive dysfunction: Translati ...   Bruner-Tran, Kaylon L; Gnecco, Juan; Ding, Tianbing; Glore, Dana R; Pensabene, Virginia; Osteen ... T32ES007028 Reprod Toxicol (2017 03) 27423904 Exiting the NIEHS site 2017 
Heme-thiolate sulfenylation of human cytochrome P450 4A11 functions as a redox switch for catalytic ...   Albertolle, Matthew E; Kim, Donghak; Nagy, Leslie D; Yun, Chul-Ho; Pozzi, Ambra; Savas, Üzen; ... T32ES007028 J Biol Chem (2017 07 07) 28533430 Exiting the NIEHS site 2017 
Human mitochondrial cytochrome P450 27C1 is localized in skin and preferentially desaturates trans-r ...   Johnson, Kevin M; Phan, Thanh T N; Albertolle, Matthew E; Guengerich, F Peter T32ES007028 J Biol Chem (2017 08 18) 28701464 Exiting the NIEHS site 2017 
In vivo bioluminescence imaging of labile iron accumulation in a murine model of Acinetobacter bauma ...   Aron, Allegra T; Heffern, Marie C; Lonergan, Zachery R; Vander Wal, Mark N; Blank, Brian R; Spa ... T32ES007028 Proc Natl Acad Sci U S A (2017 11 28) 29138321 Exiting the NIEHS site 2017 
Instrumenting a Fetal Membrane on a Chip as Emerging Technology for Preterm Birth Research.   Gnecco, Juan S; Anders, Anjali P; Cliffel, David; Pensabene, Virginia; Rogers, Lisa M; Osteen, ... T32ES007028 Curr Pharm Des (2017) 28847303 Exiting the NIEHS site 2017 
Kinetic processivity of the two-step oxidations of progesterone and pregnenolone to androgens by hum ...   Gonzalez, Eric; Guengerich, F Peter T32ES007028 J Biol Chem (2017 08 11) 28684414 Exiting the NIEHS site 2017 
Multianalyte Physiological Microanalytical Devices.   Davis, Anna Nix; Travis, Adam R; Miller, Dusty R; Cliffel, David E T32ES007028 Annu Rev Anal Chem (Palo Alto Calif) (2017 06 12) 28605606 Exiting the NIEHS site 2017 
Quantitative Analysis and Discovery of Lysine and Arginine Modifications.   Galligan, James J; Kingsley, Philip J; Wauchope, Orrette R; Mitchener, Michelle M; Camarillo, J ... T32ES007028 Anal Chem (2017 01 17) 27982582 Exiting the NIEHS site 2017 
Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse mo ...   Bichell, Terry Jo V; Wegrzynowicz, Michal; Tipps, K Grace; Bradley, Emma M; Uhouse, Michael A; ... R01ES010563, T32ES007028 Biochim Biophys Acta Mol Basis Dis (2017 06) 28213125 Exiting the NIEHS site 2017 
Relationships Between Essential Manganese Biology and Manganese Toxicity in Neurological Disease.   Pfalzer, Anna C; Bowman, Aaron B R01ES010563, T32ES007028 Curr Environ Health Rep (2017 06) 28417441 Exiting the NIEHS site 2017 
Structure of a DNA glycosylase that unhooks interstrand cross-links.   Mullins, Elwood A; Warren, Garrett M; Bradley, Noah P; Eichman, Brandt F T32ES007028 Proc Natl Acad Sci U S A (2017 04 25) 28396405 Exiting the NIEHS site 2017 
Toxicity and repair of DNA adducts produced by the natural product yatakemycin.   Mullins, Elwood A; Shi, Rongxin; Eichman, Brandt F T32ES007028 Nat Chem Biol (2017 Sep) 28759018 Exiting the NIEHS site 2017 
A Catalytic Role for C-H/π Interactions in Base Excision Repair by Bacillus cereus DNA Glycosylase A ...   Parsons, Zachary D; Bland, Joshua M; Mullins, Elwood A; Eichman, Brandt F T32ES007028 J Am Chem Soc (2016 09 14) 27571247 Exiting the NIEHS site 2016 
Assembly Dynamics and Stoichiometry of the Apoptosis Signal-regulating Kinase (ASK) Signalosome in R ...   Federspiel, Joel D; Codreanu, Simona G; Palubinsky, Amy M; Winland, Ama J; Betanzos, Carlos Mor ... T32ES007028 Mol Cell Proteomics (2016 06) 27006476 Exiting the NIEHS site 2016 
Beyond Epilepsy and Autism: Disruption of GABRB3 Causes Ocular Hypopigmentation.   Delahanty, Ryan J; Zhang, Yanfeng; Bichell, Terry Jo; Shen, Wangzhen; Verdier, Kelienne; Macdon ... T32ES007028 Cell Rep (2016 12 20) 28009282 Exiting the NIEHS site 2016 
Covalent Modification of CDK2 by 4-Hydroxynonenal as a Mechanism of Inhibition of Cell Cycle Progres ...   Camarillo, Jeannie M; Rose, Kristie L; Galligan, James J; Xu, Shu; Marnett, Lawrence J T32ES007028 Chem Res Toxicol (2016 Mar 21) 26910110 Exiting the NIEHS site 2016 
Dynamic Phosphorylation of Apoptosis Signal Regulating Kinase 1 (ASK1) in Response to Oxidative and ...   Morales Betanzos, Carlos; Federspiel, Joel D; Palubinsky, Amy M; McLaughlin, BethAnn; Liebler, ... T32ES007028 Chem Res Toxicol (2016 12 19) 27989136 Exiting the NIEHS site 2016 
Embryonic Mutant Huntingtin Aggregate Formation in Mouse Models of Huntington's Disease.   Osmand, Alexander P; Bichell, Terry Jo; Bowman, Aaron B; Bates, Gillian P T32ES007028 J Huntingtons Dis (2016 12 15) 27886014 Exiting the NIEHS site 2016 
Human cytochrome P450 27C1 catalyzes 3,4-desaturation of retinoids.   Kramlinger, Valerie M; Nagy, Leslie D; Fujiwara, Rina; Johnson, Kevin M; Phan, Thanh T N; Xiao, ... T32ES007028 FEBS Lett (2016 05) 27059013 Exiting the NIEHS site 2016 
Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein A.   Patrone, James D; Pelz, Nicholas F; Bates, Brittney S; Souza-Fagundes, Elaine M; Vangamudi, Bha ... T32ES007028 ChemMedChem (2016 Apr 19) 26748787 Exiting the NIEHS site 2016 
Interleukin-17A Regulates Renal Sodium Transporters and Renal Injury in Angiotensin II-Induced Hyper ...   Norlander, Allison E; Saleh, Mohamed A; Kamat, Nikhil V; Ko, Benjamin; Gnecco, Juan; Zhu, Linj ... T32ES007028 Hypertension (2016 07) 27141060 Exiting the NIEHS site 2016 
Multiple Time-of-Flight/Time-of-Flight Events in a Single Laser Shot for Improved Matrix-Assisted La ...   Prentice, Boone M; Chumbley, Chad W; Hachey, Brian C; Norris, Jeremy L; Caprioli, Richard M T32ES007028 Anal Chem (2016 10 04) 27573922 Exiting the NIEHS site 2016 
NAD+ Supplementation Attenuates Methylmercury Dopaminergic and Mitochondrial Toxicity in Caenorhabdi ...   Caito, Samuel W; Aschner, Michael R01ES007331, T32ES007028 Toxicol Sci (2016 05) 26865665 Exiting the NIEHS site 2016 
Oxidation of pyrene, 1-hydroxypyrene, 1-nitropyrene and 1-acetylpyrene by human cytochrome P450 2A13 ...   Shimada, Tsutomu; Takenaka, Shigeo; Murayama, Norie; Kramlinger, Valerie M; Kim, Joo-Hwan; Kim, ... T32ES007028 Xenobiotica (2016) 26247835 Exiting the NIEHS site 2016 
Rapid kinetic methods to dissect steroidogenic cytochrome P450 reaction mechanisms.   Yoshimoto, Francis K; Auchus, Richard J T32ES007028 J Steroid Biochem Mol Biol (2016 07) 26472553 Exiting the NIEHS site 2016 
Scavengers of reactive γ-ketoaldehydes extend Caenorhabditis elegans lifespan and healthspan through ...   Nguyen, Thuy T; Caito, Samuel W; Zackert, William E; West, James D; Zhu, Shijun; Aschner, Mich ... R01ES007331, R01ES010563, T32ES007028 Aging (Albany NY) (2016 08) 27514077 Exiting the NIEHS site 2016 
Specificity of Protein Covalent Modification by the Electrophilic Proteasome Inhibitor Carfilzomib i ...   Federspiel, Joel D; Codreanu, Simona G; Goyal, Sandeep; Albertolle, Matthew E; Lowe, Eric; Teag ... T32ES007028 Mol Cell Proteomics (2016 10) 27503896 Exiting the NIEHS site 2016 
The Response of Acinetobacter baumannii to Zinc Starvation.   Nairn, Brittany L; Lonergan, Zachery R; Wang, Jiefei; Braymer, Joseph J; Zhang, Yaofang; Calcut ... T32ES007028 Cell Host Microbe (2016 Jun 08) 27281572 Exiting the NIEHS site 2016 
Ultrathin Polymer Membranes with Patterned, Micrometric Pores for Organs-on-Chips.   Pensabene, Virginia; Costa, Lino; Terekhov, Alexander Y; Gnecco, Juan S; Wikswo, John P; Hofmei ... T32ES007028 ACS Appl Mater Interfaces (2016 Aug 31) 27513606 Exiting the NIEHS site 2016 
A New Family of HEAT-Like Repeat Proteins Lacking a Critical Substrate Recognition Motif Present in ...   Mullins, Elwood A; Shi, Rongxin; Kotsch, Lyle A; Eichman, Brandt F T32ES007028 PLoS One (2015) 25978435 Exiting the NIEHS site 2015 
A whole genome RNAi screen identifies replication stress response genes.   Kavanaugh, Gina; Ye, Fei; Mohni, Kareem N; Luzwick, Jessica W; Glick, Gloria; Cortez, David T32ES007028 DNA Repair (Amst) (2015 Nov) 26454783 Exiting the NIEHS site 2015 
Allosteric activation of M4 muscarinic receptors improve behavioral and physiological alterations in ...   Pancani, Tristano; Foster, Daniel J; Moehle, Mark S; Bichell, Terry Jo; Bradley, Emma; Bridges, ... T32ES007028 Proc Natl Acad Sci U S A (2015 Nov 10) 26508634 Exiting the NIEHS site 2015 
Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq ...   Wilde, Aimee D; Snyder, Daniel J; Putnam, Nicole E; Valentino, Michael D; Hammer, Neal D; Loner ... T32ES007028 PLoS Pathog (2015 Dec) 26684646 Exiting the NIEHS site 2015 
Base-Displaced Intercalated Conformation of the 2-Amino-3-methylimidazo[4,5-f]quinoline N(2)-dG DNA ...   Stavros, Kallie M; Hawkins, Edward K; Rizzo, Carmelo J; Stone, Michael P T32ES007028 Chem Res Toxicol (2015 Jul 20) 26083477 Exiting the NIEHS site 2015 
Competition and allostery govern substrate selectivity of cyclooxygenase-2.   Mitchener, Michelle M; Hermanson, Daniel J; Shockley, Erin M; Brown, H Alex; Lindsley, Craig W; ... T32ES007028 Proc Natl Acad Sci U S A (2015 Oct 06) 26392530 Exiting the NIEHS site 2015 
Cyp27c1 Red-Shifts the Spectral Sensitivity of Photoreceptors by Converting Vitamin A1 into A2.   Enright, Jennifer M; Toomey, Matthew B; Sato, Shin-ya; Temple, Shelby E; Allen, James R; Fujiwa ... T32ES007028 Curr Biol (2015 Dec 07) 26549260 Exiting the NIEHS site 2015 
Enhancer of Rudimentary Homolog Affects the Replication Stress Response through Regulation of RNA Pr ...   Kavanaugh, Gina; Zhao, Runxiang; Guo, Yan; Mohni, Kareem N; Glick, Gloria; Lacy, Monica E; Hut ... T32ES007028 Mol Cell Biol (2015 Sep 01) 26100022 Exiting the NIEHS site 2015 
High-speed MALDI MS/MS imaging mass spectrometry using continuous raster sampling.   Prentice, Boone M; Chumbley, Chad W; Caprioli, Richard M T32ES007028 J Mass Spectrom (2015 Apr) 26149115 Exiting the NIEHS site 2015 
Human Cytochrome P450 21A2, the Major Steroid 21-Hydroxylase: STRUCTURE OF THE ENZYME·PROGESTERONE S ...   Pallan, Pradeep S; Wang, Chunxue; Lei, Li; Yoshimoto, Francis K; Auchus, Richard J; Waterman, ... T32ES007028 J Biol Chem (2015 May 22) 25855791 Exiting the NIEHS site 2015 
Manganese Is Essential for Neuronal Health.   Horning, Kyle J; Caito, Samuel W; Tipps, K Grace; Bowman, Aaron B; Aschner, Michael R01ES007331, R01ES010563, T32ES007028 Annu Rev Nutr (2015) 25974698 Exiting the NIEHS site 2015 
Novel approaches to identify protein adducts produced by lipid peroxidation.   Codreanu, S G; Liebler, D C T32ES007028 Free Radic Res (2015) 25819163 Exiting the NIEHS site 2015 
Novel BAC Mouse Model of Huntington's Disease with 225 CAG Repeats Exhibits an Early Widespread and ...   Wegrzynowicz, Michal; Bichell, Terry Jo; Soares, Barbara D; Loth, Meredith K; McGlothan, Jennif ... P30ES009089, R01ES007062, T32ES007028, T32ES007322 J Huntingtons Dis (2015) 26333255 Exiting the NIEHS site 2015 
Site-specific, intramolecular cross-linking of Pin1 active site residues by the lipid electrophile 4 ...   Aluise, Christopher D; Camarillo, Jeannie M; Shimozu, Yuki; Galligan, James J; Rose, Kristie L; ... T32ES007028 Chem Res Toxicol (2015 Apr 20) 25739016 Exiting the NIEHS site 2015 
Staphylococcus aureus CstB Is a Novel Multidomain Persulfide Dioxygenase-Sulfurtransferase Involved ...   Shen, Jiangchuan; Keithly, Mary E; Armstrong, Richard N; Higgins, Khadine A; Edmonds, Katherine ... T32ES007028 Biochemistry (2015 Jul 28) 26177047 Exiting the NIEHS site 2015 
Structural and kinetic basis of steroid 17α,20-lyase activity in teleost fish cytochrome P450 17A1 a ...   Pallan, Pradeep S; Nagy, Leslie D; Lei, Li; Gonzalez, Eric; Kramlinger, Valerie M; Azumaya, Ca ... T32ES007028 J Biol Chem (2015 Feb 06) 25533464 Exiting the NIEHS site 2015 
The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.   Mullins, Elwood A; Shi, Rongxin; Parsons, Zachary D; Yuen, Philip K; David, Sheila S; Igarashi, ... T32ES007028 Nature (2015 Nov 12) 26524531 Exiting the NIEHS site 2015 
A highly sensitive method for analysis of 7-dehydrocholesterol for the study of Smith-Lemli-Opitz sy ...   Liu, Wei; Xu, Libin; Lamberson, Connor; Haas, Dorothea; Korade, Zeljka; Porter, Ned A T32ES007028 J Lipid Res (2014 Feb) 24259532 Exiting the NIEHS site 2014 
A structure-specific nucleic acid-binding domain conserved among DNA repair proteins.   Mason, Aaron C; Rambo, Robert P; Greer, Briana; Pritchett, Michael; Tainer, John A; Cortez, Da ... T32ES007028 Proc Natl Acad Sci U S A (2014 May 27) 24821763 Exiting the NIEHS site 2014 
Alkylation damage by lipid electrophiles targets functional protein systems.   Codreanu, Simona G; Ullery, Jody C; Zhu, Jing; Tallman, Keri A; Beavers, William N; Porter, Ne ... T32ES007028 Mol Cell Proteomics (2014 Mar) 24429493 Exiting the NIEHS site 2014 
Base-displaced intercalation of the 2-amino-3-methylimidazo[4,5-f]quinolone N2-dG adduct in the NarI ...   Stavros, Kallie M; Hawkins, Edward K; Rizzo, Carmelo J; Stone, Michael P T32ES007028 Nucleic Acids Res (2014 Mar) 24366876 Exiting the NIEHS site 2014 
BDNF and Huntingtin protein modifications by manganese: implications for striatal medium spiny neuro ...   Stansfield, Kirstie H; Bichell, Terry Jo; Bowman, Aaron B; Guilarte, Tomás R P30ES009089, T32ES007028 J Neurochem (2014 Dec) 25099302 Exiting the NIEHS site 2014 
Discovery of a potent stapled helix peptide that binds to the 70N domain of replication protein A.   Frank, Andreas O; Vangamudi, Bhavatarini; Feldkamp, Michael D; Souza-Fagundes, Elaine M; Luzwick ... T32ES007028 J Med Chem (2014 Mar 27) 24491171 Exiting the NIEHS site 2014 
Elucidation of kinetic mechanisms of human translesion DNA polymerase κ using tryptophan mutants.   Zhao, Linlin; Pence, Matthew G; Eoff, Robert L; Yuan, Shuai; Fercu, Catinca A; Guengerich, F P ... T32ES007028 FEBS J (2014 Oct) 25065501 Exiting the NIEHS site 2014 
Mechanism of the third oxidative step in the conversion of androgens to estrogens by cytochrome P450 ...   Yoshimoto, Francis K; Guengerich, F Peter T32ES007028 J Am Chem Soc (2014 Oct 22) 25252141 Exiting the NIEHS site 2014 
Methylmercury alters the activities of Hsp90 client proteins, prostaglandin E synthase/p23 (PGES/23) ...   Caito, Samuel; Zeng, Heng; Aschner, Judy L; Aschner, Michael R01ES007331, T32ES007028 PLoS One (2014) 24852575 Exiting the NIEHS site 2014 
Molecular basis of aflatoxin-induced mutagenesis-role of the aflatoxin B1-formamidopyrimidine adduct ...   Lin, Ying-Chih; Li, Liang; Makarova, Alena V; Burgers, Peter M; Stone, Michael P; Lloyd, R Ste ... T32ES007028 Carcinogenesis (2014 Jul) 24398669 Exiting the NIEHS site 2014 
Oxidation of endogenous N-arachidonoylserotonin by human cytochrome P450 2U1.   Siller, Michal; Goyal, Sandeep; Yoshimoto, Francis K; Xiao, Yi; Wei, Shouzou; Guengerich, F Pe ... T32ES007028 J Biol Chem (2014 Apr 11) 24563460 Exiting the NIEHS site 2014 
Phosphorylation of a C-terminal auto-inhibitory domain increases SMARCAL1 activity.   Carroll, Clinton; Bansbach, Carol E; Zhao, Runxiang; Jung, Sung Yun; Qin, Jun; Cortez, David T32ES007028 Nucleic Acids Res (2014 Jan) 24150942 Exiting the NIEHS site 2014 
Protein modification by adenine propenal.   Shuck, Sarah C; Wauchope, Orrette R; Rose, Kristie L; Kingsley, Philip J; Rouzer, Carol A; Shel ... T32ES007028 Chem Res Toxicol (2014 Oct 20) 25211669 Exiting the NIEHS site 2014 
Stable histone adduction by 4-oxo-2-nonenal: a potential link between oxidative stress and epigeneti ...   Galligan, James J; Rose, Kristie L; Beavers, William N; Hill, Salisha; Tallman, Keri A; Tansey, ... T32ES007028 J Am Chem Soc (2014 Aug 27) 25099620 Exiting the NIEHS site 2014 
The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein ...   Bornhorst, Julia; Chakraborty, Sudipta; Meyer, Sören; Lohren, Hanna; Brinkhaus, Sigrid Grosse; ... R01ES010563, T32ES007028 Metallomics (2014 Mar) 24452053 Exiting the NIEHS site 2014 
The substrate binding interface of alkylpurine DNA glycosylase AlkD.   Mullins, Elwood A; Rubinson, Emily H; Eichman, Brandt F T32ES007028 DNA Repair (Amst) (2014 Jan) 24286669 Exiting the NIEHS site 2014 
Unusual kinetic isotope effects of deuterium reinforced polyunsaturated fatty acids in tocopherol-me ...   Lamberson, Connor R; Xu, Libin; Muchalski, Hubert; Montenegro-Burke, J Rafael; Shmanai, Vadim V ... T32ES007028 J Am Chem Soc (2014 Jan 22) 24380377 Exiting the NIEHS site 2014 
An HPLC-tandem mass spectrometry method for simultaneous detection of alkylated base excision repair ...   Mullins, Elwood A; Rubinson, Emily H; Pereira, Kevin N; Calcutt, M Wade; Christov, Plamen P; Ei ... T32ES007028 Methods (2013 Nov) 23876937 Exiting the NIEHS site 2013 
Assays of plasma dehydrocholesteryl esters and oxysterols from Smith-Lemli-Opitz syndrome patients.   Liu, Wei; Xu, Libin; Lamberson, Connor R; Merkens, Louise S; Steiner, Robert D; Elias, Ellen R ... T32ES007028 J Lipid Res (2013 Jan) 23072947 Exiting the NIEHS site 2013 
ATR phosphorylates SMARCAL1 to prevent replication fork collapse.   Couch, Frank B; Bansbach, Carol E; Driscoll, Robert; Luzwick, Jessica W; Glick, Gloria G; Bétou ... R01ES016486, T32ES007028 Genes Dev (2013 Jul 15) 23873943 Exiting the NIEHS site 2013 
Cobalt carbonyl complexes as probes for alkyne-tagged lipids.   Tallman, Keri A; Armstrong, Michelle D; Milne, Stephen B; Marnett, Lawrence J; Brown, H Alex; P ... T32ES007028 J Lipid Res (2013 Mar) 23307946 Exiting the NIEHS site 2013 
Depurination of N7-methylguanine by DNA glycosylase AlkD is dependent on the DNA backbone.   Rubinson, Emily H; Christov, Plamen P; Eichman, Brandt F T32ES007028 Biochemistry (2013 Oct 22) 24090276 Exiting the NIEHS site 2013 
Differential response to acrylonitrile toxicity in rat primary astrocytes and microglia.   Caito, Samuel; Yu, Yingchun; Aschner, Michael R01ES007331, R01ES010563, T32ES007028 Neurotoxicology (2013 Jul) 23628792 Exiting the NIEHS site 2013 
Discovery of a potent inhibitor of replication protein a protein-protein interactions using a fragme ...   Frank, Andreas O; Feldkamp, Michael D; Kennedy, J Phillip; Waterson, Alex G; Pelz, Nicholas F; ... T32ES007028 J Med Chem (2013 Nov 27) 24147804 Exiting the NIEHS site 2013 
Discovery of Protein-Protein Interaction Inhibitors of Replication Protein A.   Patrone, James D; Kennedy, J Phillip; Frank, Andreas O; Feldkamp, Michael D; Vangamudi, Bhavata ... T32ES007028 ACS Med Chem Lett (2013 Jul 11) 23914285 Exiting the NIEHS site 2013 
DNA damage response: three levels of DNA repair regulation.   Sirbu, Bianca M; Cortez, David T32ES007028 Cold Spring Harb Perspect Biol (2013 Aug) 23813586 Exiting the NIEHS site 2013 
Dopaminergic neurotoxicity of S-ethyl N,N-dipropylthiocarbamate (EPTC), molinate, and S-methyl-N,N-d ...   Caito, Samuel W; Valentine, William M; Aschner, Michael R01ES007331, R01ES010563, T32ES007028 J Neurochem (2013 Dec) 23786526 Exiting the NIEHS site 2013 
Early-life exposure to methylmercury in wildtype and pdr-1/parkin knockout C. elegans.   Martinez-Finley, Ebany J; Chakraborty, Sudipta; Slaughter, James C; Aschner, Michael R01ES007331, T32ES007028 Neurochem Res (2013 Aug) 23609499 Exiting the NIEHS site 2013 
HDAC3 is essential for DNA replication in hematopoietic progenitor cells.   Summers, Alyssa R; Fischer, Melissa A; Stengel, Kristy R; Zhao, Yue; Kaiser, Jonathan F; Wells, ... T32ES007028 J Clin Invest (2013 Jul) 23921131 Exiting the NIEHS site 2013 
Histone acetyl transferase 1 is essential for mammalian development, genome stability, and the proce ...   Nagarajan, Prabakaran; Ge, Zhongqi; Sirbu, Bianca; Doughty, Cheryl; Agudelo Garcia, Paula A; Sc ... T32ES007028 PLoS Genet (2013 Jun) 23754951 Exiting the NIEHS site 2013 
Identification of proteins at active, stalled, and collapsed replication forks using isolation of pr ...   Sirbu, Bianca M; McDonald, W Hayes; Dungrawala, Huzefa; Badu-Nkansah, Akosua; Kavanaugh, Gina M ... T32ES007028 J Biol Chem (2013 Nov 01) 24047897 Exiting the NIEHS site 2013 
Inhibition of histone deacetylase 3 causes replication stress in cutaneous T cell lymphoma.   Wells, Christina E; Bhaskara, Srividya; Stengel, Kristy R; Zhao, Yue; Sirbu, Bianca; Chagot, B ... T32ES007028 PLoS One (2013) 23894374 Exiting the NIEHS site 2013 
Involvement of AAT transporters in methylmercury toxicity in Caenorhabditis elegans.   Caito, Samuel W; Zhang, Yaofang; Aschner, Michael R01ES007331, T32ES007028 Biochem Biophys Res Commun (2013 Jun 14) 23669041 Exiting the NIEHS site 2013 
Leukotriene biosynthesis inhibitor MK886 impedes DNA polymerase activity.   Ketkar, Amit; Zafar, Maroof K; Maddukuri, Leena; Yamanaka, Kinrin; Banerjee, Surajit; Egli, Ma ... T32ES007028 Chem Res Toxicol (2013 Feb 18) 23305233 Exiting the NIEHS site 2013 
Manganese efflux in Parkinsonism: insights from newly characterized SLC30A10 mutations.   DeWitt, Margaret R; Chen, Pan; Aschner, Michael R01ES010563, T32ES007028 Biochem Biophys Res Commun (2013 Mar 01) 23357421 Exiting the NIEHS site 2013 
Manganese neurotoxicity and the role of reactive oxygen species.   Martinez-Finley, Ebany J; Gavin, Claire E; Aschner, Michael; Gunter, Thomas E R01ES010563, T32ES007028 Free Radic Biol Med (2013 Sep) 23395780 Exiting the NIEHS site 2013 
Metal-induced neurodegeneration in C. elegans.   Chen, Pan; Martinez-Finley, Ebany J; Bornhorst, Julia; Chakraborty, Sudipta; Aschner, Michael R01ES010563, T32ES007028 Front Aging Neurosci (2013) 23730287 Exiting the NIEHS site 2013 
NMR studies of the interaction of calmodulin with IQ motif peptides.   Damo, Steven M; Feldkamp, Michael D; Chagot, Benjamin; Chazin, Walter J T32ES007028 Methods Mol Biol (2013) 23296611 Exiting the NIEHS site 2013 
Oxidative stress mechanisms underlying Parkinson's disease-associated neurodegeneration in C. elegan ...   Chakraborty, Sudipta; Bornhorst, Julia; Nguyen, Thuy T; Aschner, Michael R01ES007331, R01ES010563, T32ES007028 Int J Mol Sci (2013 Nov 21) 24284401 Exiting the NIEHS site 2013 
Probing lipid-protein adduction with alkynyl surrogates: application to Smith-Lemli-Opitz syndrome.   Windsor, Katherine; Genaro-Mattos, Thiago C; Kim, Hye-Young H; Liu, Wei; Tallman, Keri A; Miyam ... T32ES007028 J Lipid Res (2013 Oct) 23828810 Exiting the NIEHS site 2013 
Recent advances in the structural mechanisms of DNA glycosylases.   Brooks, Sonja C; Adhikary, Suraj; Rubinson, Emily H; Eichman, Brandt F T32ES007028 Biochim Biophys Acta (2013 Jan) 23076011 Exiting the NIEHS site 2013 
Replication, repair, and translesion polymerase bypass of N⁶-oxopropenyl-2'-deoxyadenosine.   Maddukuri, Leena; Shuck, Sarah C; Eoff, Robert L; Zhao, Linlin; Rizzo, Carmelo J; Guengerich, ... R01ES010546, T32ES007028 Biochemistry (2013 Dec 3) 24171480 Exiting the NIEHS site 2013 
Simplified synthesis of individual stereoisomers of the 4-hydroxynonenal adducts of deoxyguanosine.   Christov, Plamen P; Hawkins, Edward K; Kett, Nathan R; Rizzo, Carmelo J T32ES007028 Tetrahedron Lett (2013 Aug 07) 23935223 Exiting the NIEHS site 2013 
Structural and chemical aspects of resistance to the antibiotic fosfomycin conferred by FosB from Ba ...   Thompson, Matthew K; Keithly, Mary E; Harp, Joel; Cook, Paul D; Jagessar, Kevin L; Sulikowski, ... T32ES007028 Biochemistry (2013 Oct 15) 24004181 Exiting the NIEHS site 2013 
Substrate-selective repair and restart of replication forks by DNA translocases.   Bétous, Rémy; Couch, Frank B; Mason, Aaron C; Eichman, Brandt F; Manosas, Maria; Cortez, David T32ES007028 Cell Rep (2013 Jun 27) 23746452 Exiting the NIEHS site 2013 
Surface reengineering of RPA70N enables cocrystallization with an inhibitor of the replication prote ...   Feldkamp, Michael D; Frank, Andreas O; Kennedy, J Phillip; Patrone, James D; Vangamudi, Bhavata ... T32ES007028 Biochemistry (2013 Sep 17) 23962067 Exiting the NIEHS site 2013 
The Role of skn-1 in methylmercury-induced latent dopaminergic neurodegeneration.   Martinez-Finley, Ebany J; Caito, Samuel; Slaughter, James C; Aschner, Michael R01ES007331, T32ES007028 Neurochem Res (2013 Dec) 24194349 Exiting the NIEHS site 2013 
Xeroderma pigmentosum complementation group C protein (XPC) serves as a general sensor of damaged DN ...   Shell, Steven M; Hawkins, Edward K; Tsai, Miaw-Sheue; Hlaing, Aye Su; Rizzo, Carmelo J; Chazin, ... T32ES007028 DNA Repair (Amst) (2013 Nov) 24051049 Exiting the NIEHS site 2013 
A high-throughput fluorescence polarization anisotropy assay for the 70N domain of replication prote ...   Souza-Fagundes, Elaine M; Frank, Andreas O; Feldkamp, Michael D; Dorset, Daniel C; Chazin, Walt ... T32ES007028 Anal Biochem (2012 Feb 15) 22197419 Exiting the NIEHS site 2012 
Altered manganese homeostasis: implications for BLI-3-dependent dopaminergic neurodegeneration and S ...   Chakraborty, Sudipta; Aschner, Michael T32ES007028 J Trace Elem Med Biol (2012 Jun) 22591558 Exiting the NIEHS site 2012 
Basis of miscoding of the DNA adduct N2,3-ethenoguanine by human Y-family DNA polymerases.   Zhao, Linlin; Pence, Matthew G; Christov, Plamen P; Wawrzak, Zdzislaw; Choi, Jeong-Yun; Rizzo, ... R01ES010546, T32ES007028 J Biol Chem (2012 Oct 12) 22910910 Exiting the NIEHS site 2012 
Cellular transport and homeostasis of essential and nonessential metals.   Martinez-Finley, Ebany J; Chakraborty, Sudipta; Fretham, Stephanie J B; Aschner, Michael R01ES007331, R01ES010563, T32ES007028 Metallomics (2012 Jul) 22337135 Exiting the NIEHS site 2012 
Electrophilic adduction of ubiquitin activating enzyme E1 by N,N-diethyldithiocarbamate inhibits ubi ...   Viquez, Olga M; Caito, Samuel W; McDonald, W Hayes; Friedman, David B; Valentine, William M T32ES007028 Chem Res Toxicol (2012 Nov 19) 22874009 Exiting the NIEHS site 2012 
Genome-Wide Analyses of Metal Responsive Genes in Caenorhabditis elegans.   Caito, Samuel; Fretham, Stephanie; Martinez-Finley, Ebany; Chakraborty, Sudipta; Avila, Daiana; ... R01ES007331, R01ES010563, T32ES007028 Front Genet (2012) 22514555 Exiting the NIEHS site 2012 
Mechanisms and Modifiers of Methylmercury-Induced Neurotoxicity.   Fretham, Stephanie Jb; Caito, Samuel; Martinez-Finley, Ebany J; Aschner, Michael R01ES007331, R01ES010563, T32ES007028 Toxicol Res (Camb) (2012 Jul 01) 27795823 Exiting the NIEHS site 2012 
Nucleic acid recognition by tandem helical repeats.   Rubinson, Emily H; Eichman, Brandt F T32ES007028 Curr Opin Struct Biol (2012 Feb) 22154606 Exiting the NIEHS site 2012 
Oxidation of dihydrotestosterone by human cytochromes P450 19A1 and 3A4.   Cheng, Qian; Sohl, Christal D; Yoshimoto, Francis K; Guengerich, F Peter T32ES007028 J Biol Chem (2012 Aug 24) 22773874 Exiting the NIEHS site 2012 
Oxidation of methyl and ethyl nitrosamines by cytochrome P450 2E1 and 2B1.   Chowdhury, Goutam; Calcutt, M Wade; Nagy, Leslie D; Guengerich, F Peter T32ES007028 Biochemistry (2012 Dec 18) 23186213 Exiting the NIEHS site 2012 
Replication of N2,3-ethenoguanine by DNA polymerases.   Zhao, Linlin; Christov, Plamen P; Kozekov, Ivan D; Pence, Matthew G; Pallan, Pradeep S; Rizzo, ... R01ES010546, T32ES007028 Angew Chem Int Ed Engl (2012 May 29) 22488769 Exiting the NIEHS site 2012 
SMARCAL1 catalyzes fork regression and Holliday junction migration to maintain genome stability duri ...   Bétous, Rémy; Mason, Aaron C; Rambo, Robert P; Bansbach, Carol E; Badu-Nkansah, Akosua; Sirbu, ... T32ES007028 Genes Dev (2012 Jan 15) 22279047 Exiting the NIEHS site 2012 
Synthesis of bacillithiol and the catalytic selectivity of FosB-type fosfomycin resistance proteins.   Lamers, Alexander P; Keithly, Mary E; Kim, Kwangho; Cook, Paul D; Stec, Donald F; Hines, Kelly ... T32ES007028 Org Lett (2012 Oct 19) 23030527 Exiting the NIEHS site 2012 
XPF-ERCC1: on the bubble.   Shell, Steven M; Chazin, Walter J T32ES007028 Structure (2012 Apr 04) 22483102 Exiting the NIEHS site 2012 
A single chiroptical spectroscopic method may not be able to establish the absolute configurations o ...   Polavarapu, Prasad L; Donahue, Emily A; Shanmugam, Ganesh; Scalmani, Giovanni; Hawkins, Edward ... T32ES007028 J Phys Chem A (2011 Jun 09) 21568330 Exiting the NIEHS site 2011 
Importance of solvation in understanding the chiroptical spectra of natural products in solution pha ...   Polavarapu, Prasad L; Scalmani, Giovanni; Hawkins, Edward K; Rizzo, Carmelo; Jeirath, Neha; Ibn ... T32ES007028 J Nat Prod (2011 Mar 25) 21114277 Exiting the NIEHS site 2011 
Insights from Caenorhabditis elegans on the role of metals in neurodegenerative diseases.   Martinez-Finley, Ebany J; Avila, Daiana Silva; Chakraborty, Sudipta; Aschner, Michael R01ES007331, R01ES010563, T32ES007028 Metallomics (2011 Mar) 21210060 Exiting the NIEHS site 2011 
Lack of association between autism and four heavy metal regulatory genes.   Owens, Sarah E; Summar, Marshall L; Ryckman, Kelli K; Haines, Jonathan L; Reiss, Sara; Summar, ... R01ES007331, T32ES007028 Neurotoxicology (2011 Dec) 21798283 Exiting the NIEHS site 2011 
Location of inhibitor binding sites in the human inducible prostaglandin E synthase, MPGES1.   Prage, Edward B; Pawelzik, Sven-Christian; Busenlehner, Laura S; Kim, Kwangho; Morgenstern, Ral ... T32ES007028 Biochemistry (2011 Sep 06) 21805999 Exiting the NIEHS site 2011 
Mefloquine neurotoxicity is mediated by non-receptor tyrosine kinase.   Milatovic, Dejan; Jenkins, Jerry W; Hood, Jonathan E; Yu, Yingchun; Rongzhu, Lu; Aschner, Mich ... R01ES007331, R01ES010563, T32ES007028 Neurotoxicology (2011 Oct) 21241737 Exiting the NIEHS site 2011 
Multi-step oxidations catalyzed by cytochrome P450 enzymes: Processive vs. distributive kinetics and ...   Guengerich, F Peter; Sohl, Christal D; Chowdhury, Goutam T32ES007028 Arch Biochem Biophys (2011 Mar 01) 20804723 Exiting the NIEHS site 2011 
Progression of neurodegeneration and morphologic changes in the brains of juvenile mice with selenop ...   Caito, Samuel W; Milatovic, Dejan; Hill, Kristina E; Aschner, Michael; Burk, Raymond F; Valenti ... T32ES007028 Brain Res (2011 Jun 29) 21636077 Exiting the NIEHS site 2011 
Roles of the four DNA polymerases of the crenarchaeon Sulfolobus solfataricus and accessory proteins ...   Choi, Jeong-Yun; Eoff, Robert L; Pence, Matthew G; Wang, Jian; Martin, Martha V; Kim, Eun-Jin; ... T32ES007028 J Biol Chem (2011 Sep 09) 21784862 Exiting the NIEHS site 2011 
Structure and function of YghU, a nu-class glutathione transferase related to YfcG from Escherichia ...   Stourman, Nina V; Branch, Megan C; Schaab, Matthew R; Harp, Joel M; Ladner, Jane E; Armstrong, ... T32ES007028 Biochemistry (2011 Feb 22) 21222452 Exiting the NIEHS site 2011 
Structure-activity analysis of diffusible lipid electrophiles associated with phospholipid peroxidat ...   McGrath, Colleen E; Tallman, Keri A; Porter, Ned A; Marnett, Lawrence J T32ES007028 Chem Res Toxicol (2011 Mar 21) 21291287 Exiting the NIEHS site 2011 
An unprecedented nucleic acid capture mechanism for excision of DNA damage.   Rubinson, Emily H; Gowda, A S Prakasha; Spratt, Thomas E; Gold, Barry; Eichman, Brandt F T32ES007028 Nature (2010 Nov 18) 20927102 Exiting the NIEHS site 2010 
Hormetic effect of methylmercury on Caenorhabditis elegans.   Helmcke, Kirsten J; Aschner, Michael R01ES007331, R01ES010563, T32ES007028 Toxicol Appl Pharmacol (2010 Oct 15) 20691719 Exiting the NIEHS site 2010 
Kinetic analysis of the three-step steroid aromatase reaction of human cytochrome P450 19A1.   Sohl, Christal D; Guengerich, F Peter T32ES007028 J Biol Chem (2010 Jun 04) 20385561 Exiting the NIEHS site 2010 
Molecular analysis of tumor margins by MALDI mass spectrometry in renal carcinoma.   Oppenheimer, Stacey R; Mi, Deming; Sanders, Melinda E; Caprioli, Richard M T32ES007028 J Proteome Res (2010 May 07) 20141219 Exiting the NIEHS site 2010 
Mutagenicity of a glutathione conjugate of butadiene diepoxide.   Cho, Sung-Hee; Loecken, Elisabeth M; Guengerich, F Peter R01ES010546, T32ES007028 Chem Res Toxicol (2010 Oct 18) 20879737 Exiting the NIEHS site 2010 
Oxidation of N-Nitrosoalkylamines by human cytochrome P450 2A6: sequential oxidation to aldehydes an ...   Chowdhury, Goutam; Calcutt, M Wade; Guengerich, F Peter T32ES007028 J Biol Chem (2010 Mar 12) 20061389 Exiting the NIEHS site 2010 
Structural basis for proficient incorporation of dTTP opposite O6-methylguanine by human DNA polymer ...   Pence, Matthew G; Choi, Jeong-Yun; Egli, Martin; Guengerich, F Peter T32ES007028 J Biol Chem (2010 Dec 24) 20961860 Exiting the NIEHS site 2010 
The C8-2'-deoxyguanosine adduct of 2-amino-3-methylimidazo[1,2-d]naphthalene, a carbocyclic analogue ...   Christov, Plamen P; Chowdhury, Goutam; Garmendia, Craig A; Wang, Feng; Stover, James S; Elmquis ... T32ES007028 Chem Res Toxicol (2010 Jun 21) 20377178 Exiting the NIEHS site 2010 
Tyrosine-lipid peroxide adducts from radical termination: para coupling and intramolecular Diels-Ald ...   Shchepin, Roman; Möller, Matias N; Kim, Hye-young H; Hatch, Duane M; Bartesaghi, Silvina; Kalya ... T32ES007028 J Am Chem Soc (2010 Dec 15) 21090613 Exiting the NIEHS site 2010 
Characterization of an AM404 analogue, N-(3-hydroxyphenyl)arachidonoylamide, as a substrate and inac ...   Turman, Melissa V; Kingsley, Philip J; Marnett, Lawrence J T32ES007028 Biochemistry (2009 Dec 29) 19928795 Exiting the NIEHS site 2009 
Characterization of the effects of methylmercury on Caenorhabditis elegans.   Helmcke, Kirsten J; Syversen, Tore; Miller 3rd, David M; Aschner, Michael R01ES007331, T32ES007028 Toxicol Appl Pharmacol (2009 Oct 15) 19341752 Exiting the NIEHS site 2009 
Evolution of the antibiotic resistance protein, FosA, is linked to a catalytically promiscuous proge ...   Brown, Daniel W; Schaab, Matthew R; Birmingham, William R; Armstrong, Richard N T32ES007028 Biochemistry (2009 Mar 10) 19196010 Exiting the NIEHS site 2009 
Oxidation and glycolytic cleavage of etheno and propano DNA base adducts.   Knutson, Charles G; Rubinson, Emily H; Akingbade, Dapo; Anderson, Carolyn S; Stec, Donald F; Pe ... R01ES010546, T32ES007028 Biochemistry (2009 Feb 3) 19132922 Exiting the NIEHS site 2009 
The bis-electrophile diepoxybutane cross-links DNA to human histones but does not result in enhanced ...   Loecken, Elisabeth M; Dasari, Surendra; Hill, Salisha; Tabb, David L; Guengerich, F Peter R01ES010546, T32ES007028 Chem Res Toxicol (2009 Jun) 19364102 Exiting the NIEHS site 2009 
"One-pot" syntheses of malondialdehyde adducts of nucleosides.   Szekely, Jozsef; Wang, Hao; Peplowski, Katherine M; Knutson, Charles G; Marnett, Lawrence J; Ri ... T32ES007028 Nucleosides Nucleotides Nucleic Acids (2008 Feb) 18205065 Exiting the NIEHS site 2008 
A new protein architecture for processing alkylation damaged DNA: the crystal structure of DNA glyco ...   Rubinson, Emily H; Metz, Audrey H; O'Quin, Jami; Eichman, Brandt F T32ES007028 J Mol Biol (2008 Aug 01) 18585735 Exiting the NIEHS site 2008 
Cooperativity of cytochrome P450 1A2: interactions of 1,4-phenylene diisocyanide and 1-isopropoxy-4- ...   Isin, Emre M; Sohl, Christal D; Eoff, Robert L; Guengerich, F Peter T32ES007028 Arch Biochem Biophys (2008 May 1) 18328798 Exiting the NIEHS site 2008 
Formation of DNA-protein cross-links between gamma-hydroxypropanodeoxyguanosine and EcoRI.   VanderVeen, Laurie A; Harris, Thomas M; Jen-Jacobson, Linda; Marnett, Lawrence J T32ES007028 Chem Res Toxicol (2008 Sep) 18690724 Exiting the NIEHS site 2008 
Mitochondrial protein targets of thiol-reactive electrophiles.   Wong, Hansen L; Liebler, Daniel C T32ES007028 Chem Res Toxicol (2008 Apr) 18324786 Exiting the NIEHS site 2008 
Monitoring in vivo metabolism and elimination of the endogenous DNA adduct, M1dG {3-(2-deoxy-beta-D- ...   Knutson, Charles G; Skipper, Paul L; Liberman, Rosa G; Tannenbaum, Steven R; Marnett, Lawrence ... P30ES002109, T32ES007028 Chem Res Toxicol (2008 Jun) 18461974 Exiting the NIEHS site 2008 
mRNA distribution and heterologous expression of orphan cytochrome P450 20A1.   Stark, Katarina; Wu, Zhong-Liu; Bartleson, Cheryl J; Guengerich, F Peter T32ES007028 Drug Metab Dispos (2008 Sep) 18541694 Exiting the NIEHS site 2008 
Oxidative metabolism of a fatty acid amide hydrolase-regulated lipid, arachidonoyltaurine.   Turman, Melissa V; Kingsley, Philip J; Rouzer, Carol A; Cravatt, Benjamin F; Marnett, Lawrence ... T32ES007028 Biochemistry (2008 Mar 25) 18311922 Exiting the NIEHS site 2008 
Protein damage by reactive electrophiles: targets and consequences.   Liebler, Daniel C T32ES007028 Chem Res Toxicol (2008 Jan) 18052106 Exiting the NIEHS site 2008 
Reactions of glyceraldehyde 3-phosphate dehydrogenase sulfhydryl groups with bis-electrophiles produ ...   Loecken, Elisabeth M; Guengerich, F Peter R01ES010546, T32ES007028 Chem Res Toxicol (2008 Feb) 18163542 Exiting the NIEHS site 2008 
Structural elements involved in proton translocation by cytochrome c oxidase as revealed by backbone ...   Busenlehner, Laura S; Brändén, Gisela; Namslauer, Ida; Brzezinski, Peter; Armstrong, Richard N T32ES007028 Biochemistry (2008 Jan 8) 18052347 Exiting the NIEHS site 2008 
2-Hydroxychromene-2-carboxylic acid isomerase: a kappa class glutathione transferase from Pseudomona ...   Thompson, Lawrence C; Ladner, Jane E; Codreanu, Simona G; Harp, Joel; Gilliland, Gary L; Armstr ... T32ES007028 Biochemistry (2007 Jun 12) 17508726 Exiting the NIEHS site 2007 
A model for glutathione binding and activation in the fosfomycin resistance protein, FosA.   Rigsby, Rachel E; Brown, Daniel W; Dawson, Eric; Lybrand, Terry P; Armstrong, Richard N T32ES007028 Arch Biochem Biophys (2007 Aug 15) 17537395 Exiting the NIEHS site 2007 
Chemical and electrochemical oxidation of C8-arylamine adducts of 2'-deoxyguanosine.   Stover, James S; Ciobanu, Madalina; Cliffel, David E; Rizzo, Carmelo J T32ES007028 J Am Chem Soc (2007 Feb 21) 17256856 Exiting the NIEHS site 2007 
Conformational differences of the C8-deoxyguanosine adduct of 2-amino-3-methylimidazo[4,5-f]quinolin ...   Elmquist, C Eric; Wang, Feng; Stover, James S; Stone, Michael P; Rizzo, Carmelo J T32ES007028 Chem Res Toxicol (2007 Mar) 17311423 Exiting the NIEHS site 2007 
DNA sequence modulates the conformation of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline ...   Wang, Feng; Elmquist, C Eric; Stover, James S; Rizzo, Carmelo J; Stone, Michael P T32ES007028 Biochemistry (2007 Jul 24) 17602664 Exiting the NIEHS site 2007 
Effect of alterations of key active site residues in O6-alkylguanine-DNA Alkyltransferase on its abi ...   Liu, Liping; Watanabe, Kengo; Fang, Qingming; Williams, Kevin M; Guengerich, F Peter; Pegg, An ... R01ES010546, T32ES007028 Chem Res Toxicol (2007 Jan) 17226938 Exiting the NIEHS site 2007 
Electron transport pathway for a Streptomyces cytochrome P450: cytochrome P450 105D5-catalyzed fatty ...   Chun, Young-Jin; Shimada, Tsutomu; Sanchez-Ponce, Raymundo; Martin, Martha V; Lei, Li; Zhao, B ... T32ES007028 J Biol Chem (2007 Jun 15) 17446171 Exiting the NIEHS site 2007 
Identification of the peroxidation products of 13-hydroxy-gamma-linolenate and 15-hydroxyarachidonat ...   Rector, Christopher L; Stec, Donald F; Brash, Alan R; Porter, Ned A T32ES007028 Chem Res Toxicol (2007 Nov) 17907784 Exiting the NIEHS site 2007 
In vivo oxidative damage in rats is associated with barbiturate response but not other cytochrome P4 ...   Dostalek, Miroslav; Brooks, Joshua D; Hardy, Klarissa D; Milne, Ginger L; Moore, Megan M; Sharm ... T32ES007028 Mol Pharmacol (2007 Dec) 17898314 Exiting the NIEHS site 2007 
Location of substrate binding sites within the integral membrane protein microsomal glutathione tran ...   Busenlehner, Laura S; Alander, Johan; Jegerscöhld, Caroline; Holm, Peter J; Bhakat, Priyaranjan ... T32ES007028 Biochemistry (2007 Mar 13) 17297922 Exiting the NIEHS site 2007 
Metabolism and elimination of the endogenous DNA adduct, 3-(2-deoxy-beta-D-erythropentofuranosyl)-py ...   Knutson, Charles G; Wang, Hao; Rizzo, Carmelo J; Marnett, Lawrence J T32ES007028 J Biol Chem (2007 Dec 14) 17951255 Exiting the NIEHS site 2007 
Metabolism in vitro and in vivo of the DNA base adduct, M1G.   Knutson, Charles G; Akingbade, Dapo; Crews, Brenda C; Voehler, Markus; Stec, Donald F; Marnett, ... T32ES007028 Chem Res Toxicol (2007 Mar) 17311424 Exiting the NIEHS site 2007 
Oxidative metabolism of lipoamino acids and vanilloids by lipoxygenases and cyclooxygenases.   Prusakiewicz, Jeffery J; Turman, Melissa V; Vila, Andrew; Ball, Heather L; Al-Mestarihi, Ahmad ... T32ES007028 Arch Biochem Biophys (2007 Aug 15) 17493578 Exiting the NIEHS site 2007 
Structural basis of enantioselective inhibition of cyclooxygenase-1 by S-alpha-substituted indometha ...   Harman, Christine A; Turman, Melissa V; Kozak, Kevin R; Marnett, Lawrence J; Smith, William L; ... T32ES007028 J Biol Chem (2007 Sep 21) 17656360 Exiting the NIEHS site 2007 
Structure and mechanism of the genomically encoded fosfomycin resistance protein, FosX, from Listeri ...   Fillgrove, Kerry L; Pakhomova, Svetlana; Schaab, Matthew R; Newcomer, Marcia E; Armstrong, Rich ... T32ES007028 Biochemistry (2007 Jul 10) 17567049 Exiting the NIEHS site 2007 
Structure of the 1,N2-etheno-2'-deoxyguanosine adduct in duplex DNA at pH 8.6.   Shanmugam, Ganesh; Goodenough, Angela K; Kozekov, Ivan D; Guengerich, F Peter; Rizzo, Carmelo J ... T32ES007028 Chem Res Toxicol (2007 Nov) 17941687 Exiting the NIEHS site 2007 
Synthesis of oligonucleotides containing the N2-deoxyguanosine adduct of the dietary carcinogen 2-am ...   Stover, James S; Rizzo, Carmelo J T32ES007028 Chem Res Toxicol (2007 Dec) 17914884 Exiting the NIEHS site 2007 
Untargeted analysis of mass spectrometry data for elucidation of metabolites and function of enzymes ...   Sanchez-Ponce, Raymundo; Guengerich, F Peter T32ES007028 Anal Chem (2007 May 1) 17408243 Exiting the NIEHS site 2007 
Base-displaced intercalated structure of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in ...   Wang, Feng; DeMuro, Nicholas E; Elmquist, C Eric; Stover, James S; Rizzo, Carmelo J; Stone, Mi ... T32ES007028 J Am Chem Soc (2006 Aug 9) 16881637 Exiting the NIEHS site 2006 
Biochemical basis of genotoxicity of heterocyclic arylamine food mutagens: Human DNA polymerase eta ...   Choi, Jeong-Yun; Stover, James S; Angel, Karen C; Chowdhury, Goutam; Rizzo, Carmelo J; Guengeri ... T32ES007028 J Biol Chem (2006 Sep 01) 16835218 Exiting the NIEHS site 2006 
Double mutation at the subunit interface of glutathione transferase rGSTM1-1 results in a stable, fo ...   Thompson, Lawrence C; Walters, John; Burke, Jonathan; Parsons, James F; Armstrong, Richard N; D ... T32ES007028 Biochemistry (2006 Feb 21) 16475815 Exiting the NIEHS site 2006 
In vivo oxidative metabolism of a major peroxidation-derived DNA adduct, M1dG.   Otteneder, Michael B; Knutson, Charles G; Daniels, J Scott; Hashim, Muhammed; Crews, Brenda C; ... T32ES007028 Proc Natl Acad Sci U S A (2006 Apr 25) 16614064 Exiting the NIEHS site 2006 
Inhibition of protein phosphatase 2A activity by selective electrophile alkylation damage.   Codreanu, Simona G; Adams, Deanna G; Dawson, Eric S; Wadzinski, Brian E; Liebler, Daniel C T32ES007028 Biochemistry (2006 Aug 22) 16906760 Exiting the NIEHS site 2006 
Mapping protein dynamics in catalytic intermediates of the redox-driven proton pump cytochrome c oxi ...   Busenlehner, Laura S; Salomonsson, Lina; Brzezinski, Peter; Armstrong, Richard N T32ES007028 Proc Natl Acad Sci U S A (2006 Oct 17) 17023543 Exiting the NIEHS site 2006 
Translesion synthesis across 1,N2-ethenoguanine by human DNA polymerases.   Choi, Jeong-Yun; Zang, Hong; Angel, Karen C; Kozekov, Ivan D; Goodenough, Angela K; Rizzo, Car ... T32ES007028 Chem Res Toxicol (2006 Jun) 16780368 Exiting the NIEHS site 2006 
Translesion synthesis past the C8- and N2-deoxyguanosine adducts of the dietary mutagen 2-Amino-3-me ...   Stover, James S; Chowdhury, Goutam; Zang, Hong; Guengerich, F Peter; Rizzo, Carmelo J T32ES007028 Chem Res Toxicol (2006 Nov) 17112239 Exiting the NIEHS site 2006 
Cytochrome P450 3A4-catalyzed testosterone 6beta-hydroxylation stereochemistry, kinetic deuterium is ...   Krauser, Joel A; Guengerich, F Peter T32ES007028 J Biol Chem (2005 May 20) 15772082 Exiting the NIEHS site 2005 
Differential DNA recognition and cleavage by EcoRI dependent on the dynamic equilibrium between the ...   VanderVeen, Laurie A; Druckova, Alexandra; Riggins, James N; Sorrells, Jennifer L; Guengerich, ... T32ES007028 Biochemistry (2005 Apr 5) 15794640 Exiting the NIEHS site 2005 
DNA adduct bypass polymerization by Sulfolobus solfataricus DNA polymerase Dpo4: analysis and crysta ...   Zang, Hong; Goodenough, Angela K; Choi, Jeong-Yun; Irimia, Adriana; Loukachevitch, Lioudmila V; ... T32ES007028 J Biol Chem (2005 Aug 19) 15965231 Exiting the NIEHS site 2005 
Exocyclic DNA lesions stimulate DNA cleavage mediated by human topoisomerase II alpha in vitro and i ...   Vélez-Cruz, Renier; Riggins, James N; Daniels, J Scott; Cai, Hongliang; Guengerich, F Peter; Ma ... T32ES007028 Biochemistry (2005 Mar 15) 15751973 Exiting the NIEHS site 2005 
Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation.   Gao, Nan; Ishii, Kenichiro; Mirosevich, Janni; Kuwajima, Satoru; Oppenheimer, Stacey R; Roberts ... T32ES007028 Development (2005 Aug) 15987773 Exiting the NIEHS site 2005 
Identification and analysis of products formed from phospholipids in the free radical oxidation of h ...   Milne, Ginger L; Seal, Jennifer R; Havrilla, Christine M; Wijtmans, Maikel; Porter, Ned A T32ES007028 J Lipid Res (2005 Feb) 15547297 Exiting the NIEHS site 2005 
Influence of the dimer interface on glutathione transferase structure and dynamics revealed by amide ...   Codreanu, Simona G; Thompson, Lawrence C; Hachey, David L; Dirr, Heini W; Armstrong, Richard N T32ES007028 Biochemistry (2005 Aug 09) 16060669 Exiting the NIEHS site 2005 
Insights into enzyme structure and dynamics elucidated by amide H/D exchange mass spectrometry.   Busenlehner, Laura S; Armstrong, Richard N T32ES007028 Arch Biochem Biophys (2005 Jan 01) 15581564 Exiting the NIEHS site 2005 
Lipid-soluble 3-pyridinol antioxidants spare alpha-tocopherol and do not efficiently mediate peroxid ...   Kim, Hye-Young; Pratt, Derek A; Seal, Jennifer R; Wijtmans, Maikel; Porter, Ned A T32ES007028 J Med Chem (2005 Nov 3) 16250637 Exiting the NIEHS site 2005 
Peroxidation of polyunsaturated fatty acid methyl esters catalyzed by N-methyl benzohydroxamic acid: ...   Punta, Carlo; Rector, Christopher L; Porter, Ned A T32ES007028 Chem Res Toxicol (2005 Feb) 15720142 Exiting the NIEHS site 2005 
Site specific synthesis and polymerase bypass of oligonucleotides containing a 6-hydroxy-3,5,6,7-tet ...   Goodenough, Angela K; Kozekov, Ivan D; Zang, Hong; Choi, Jeong-Yun; Guengerich, F Peter; Harris ... T32ES007028 Chem Res Toxicol (2005 Nov) 16300379 Exiting the NIEHS site 2005 
Characterization of a mutagenic DNA adduct formed from 1,2-dibromoethane by O6-alkylguanine-DNA alky ...   Liu, Liping; Hachey, David L; Valadez, Gerardo; Williams, Kevin M; Guengerich, F Peter; Loktion ... R01ES010546, T32ES007028 J Biol Chem (2004 Feb 06) 14645247 Exiting the NIEHS site 2004 
Coupling products of nucleosides with the glyoxal adduct of deoxyguanosine.   Brock, Angela K; Kozekov, Ivan D; Rizzo, Carmelo J; Harris, Thomas M T32ES007028 Chem Res Toxicol (2004 Aug) 15310236 Exiting the NIEHS site 2004 
Factors influencing the autoxidation of fatty acids: effect of olefin geometry of the nonconjugated ...   Tallman, Keri A; Roschek Jr, Bill; Porter, Ned A T32ES007028 J Am Chem Soc (2004 Aug 4) 15281813 Exiting the NIEHS site 2004 
Generation of new protein kinase inhibitors utilizing cytochrome p450 mutant enzymes for indigoid sy ...   Guengerich, F Peter; Sorrells, Jennifer L; Schmitt, Sophie; Krauser, Joel A; Aryal, Pramod; Mei ... T32ES007028 J Med Chem (2004 Jun 03) 15163202 Exiting the NIEHS site 2004 
Global shifts in protein sumoylation in response to electrophile and oxidative stress.   Manza, Linda L; Codreanu, Simona G; Stamer, Sheryl L; Smith, Darrin L; Wells, K Sam; Roberts, ... T32ES007028 Chem Res Toxicol (2004 Dec) 15606148 Exiting the NIEHS site 2004 
In vitro bypass of malondialdehyde-deoxyguanosine adducts: differential base selection during extens ...   Hashim, Muhammed F; Riggins, James N; Schnetz-Boutaud, Nathalie; Voehler, Markus; Stone, Michae ... T32ES007028 Biochemistry (2004 Sep 21) 15362868 Exiting the NIEHS site 2004 
Kinetic and thermodynamic analysis of the hydrolytic ring-opening of the malondialdehyde-deoxyguanos ...   Riggins, James N; Daniels, J Scott; Rouzer, Carol A; Marnett, Lawrence J T32ES007028 J Am Chem Soc (2004 Jul 7) 15225065 Exiting the NIEHS site 2004 
Kinetics and mechanism of the general-acid-catalyzed ring-closure of the malondialdehyde-DNA adduct, ...   Riggins, James N; Pratt, Derek A; Voehler, Markus; Daniels, J Scott; Marnett, Lawrence J T32ES007028 J Am Chem Soc (2004 Sep 1) 15327313 Exiting the NIEHS site 2004 
Liquid chromatography coordination ion-spray mass spectrometry (LC-CIS-MS) of docosahexaenoate ester ...   Seal, Jennifer R; Porter, Ned A T32ES007028 Anal Bioanal Chem (2004 Feb) 14634702 Exiting the NIEHS site 2004 
N,N-diethyldithiocarbamate produces copper accumulation, lipid peroxidation, and myelin injury in ra ...   Tonkin, Elizabeth G; Valentine, Holly L; Milatovic, Dejan M; Valentine, William M T32ES007028 Toxicol Sci (2004 Sep) 15187237 Exiting the NIEHS site 2004 
O6-alkylguanine-DNA alkyltransferase has opposing effects in modulating the genotoxicity of dibromom ...   Liu, Liping; Williams, Kevin M; Guengerich, F Peter; Pegg, Anthony E R01ES010546, T32ES007028 Chem Res Toxicol (2004 Jun) 15206895 Exiting the NIEHS site 2004 
Parallel evolutionary pathways for glutathione transferases: structure and mechanism of the mitochon ...   Ladner, Jane E; Parsons, James F; Rife, Chris L; Gilliland, Gary L; Armstrong, Richard N T32ES007028 Biochemistry (2004 Jan 20) 14717589 Exiting the NIEHS site 2004 
Phosphonoformate: a minimal transition state analogue inhibitor of the fosfomycin resistance protein ...   Rigsby, Rachel E; Rife, Chris L; Fillgrove, Kerry L; Newcomer, Marcia E; Armstrong, Richard N T32ES007028 Biochemistry (2004 Nov 2) 15504029 Exiting the NIEHS site 2004 
Rate-limiting steps in oxidations catalyzed by rabbit cytochrome P450 1A2.   Guengerich, F Peter; Krauser, Joel A; Johnson, William W T32ES007028 Biochemistry (2004 Aug 24) 15311939 Exiting the NIEHS site 2004 
Site-specific synthesis and properties of oligonucleotides containing C8-deoxyguanosine adducts of t ...   Elmquist, C Eric; Stover, James S; Wang, Zhiwei; Rizzo, Carmelo J T32ES007028 J Am Chem Soc (2004 Sep 15) 15355100 Exiting the NIEHS site 2004 
Stress sensor triggers conformational response of the integral membrane protein microsomal glutathio ...   Busenlehner, Laura S; Codreanu, Simona G; Holm, Peter J; Bhakat, Priyaranjan; Hebert, Hans; Mor ... T32ES007028 Biochemistry (2004 Sep 07) 15366924 Exiting the NIEHS site 2004 
Synthesis of the N2-deoxyguanosine adduct of the potent dietary mutagen IQ.   Stover, James S; Rizzo, Carmelo J T32ES007028 Org Lett (2004 Dec 23) 15606116 Exiting the NIEHS site 2004 
Testosterone 1 beta-hydroxylation by human cytochrome P450 3A4.   Krauser, Joel A; Voehler, Markus; Tseng, Li-Hong; Schefer, Alexandre B; Godejohann, Markus; Gue ... T32ES007028 Eur J Biochem (2004 Oct) 15373842 Exiting the NIEHS site 2004 
Analysis of unsaturated compounds by Ag+ coordination ionspray mass spectrometry: studies of the for ...   Seal, Jennifer R; Havrilla, Christine M; Porter, Ned A; Hachey, David L T32ES007028 J Am Soc Mass Spectrom (2003 Aug) 12892911 Exiting the NIEHS site 2003 
Catalytic mechanism of dichloromethane dehalogenase from Methylophilus sp. strain DM11.   Stourman, Nina V; Rose, James H; Vuilleumier, Stephane; Armstrong, Richard N T32ES007028 Biochemistry (2003 Sep 23) 12974641 Exiting the NIEHS site 2003 
Characterizing the influence of structure and route of exposure on the disposition of dithiocarbamat ...   Johnson, D J; Amarnath, V; Amarnath, K; Valentine, H; Valentine, W M T32ES007028 Toxicol Sci (2003 Nov) 12972631 Exiting the NIEHS site 2003 
Induction of frameshift and base pair substitution mutations by the major DNA adduct of the endogeno ...   VanderVeen, Laurie A; Hashim, Muhammed F; Shyr, Yu; Marnett, Lawrence J T32ES007028 Proc Natl Acad Sci U S A (2003 Nov 25) 14603032 Exiting the NIEHS site 2003 
Mechanistic diversity of fosfomycin resistance in pathogenic microorganisms.   Fillgrove, Kerry L; Pakhomova, Svetlana; Newcomer, Marcia E; Armstrong, Richard N T32ES007028 J Am Chem Soc (2003 Dec 24) 14677948 Exiting the NIEHS site 2003 
Mercapturate metabolism of 4-hydroxy-2-nonenal in rat and human cerebrum.   Sidell, Kathrin R; Montine, Kathleen S; Picklo Sr, Matrhew J; Olsen, Sandra J; Amarnath, Ventka ... T32ES007028 J Neuropathol Exp Neurol (2003 Feb) 12578224 Exiting the NIEHS site 2003 
Parenteral N,N-diethyldithiocarbamate produces segmental demyelination in the rat that is not depend ...   Tonkin, Elizabeth G; Valentine, Holly L; Zimmerman, Lisa J; Valentine, William M T32ES007028 Toxicol Appl Pharmacol (2003 Jun 01) 12781632 Exiting the NIEHS site 2003 
Catalysis of catechol oxidation by metal-dithiocarbamate complexes in pesticides.   Fitsanakis, Vanessa A; Amarnath, Venkataraman; Moore, Joshua T; Montine, Kathleen S; Zhang, Jin ... T32ES007028 Free Radic Biol Med (2002 Dec 15) 12488139 Exiting the NIEHS site 2002 
DNA adducts of acrolein: site-specific synthesis of an oligodeoxynucleotide containing 6-hydroxy-5,6 ...   Nechev, Lubomir V; Kozekov, Ivan D; Brock, Angela K; Rizzo, Carmelo J; Harris, Thomas M T32ES007028 Chem Res Toxicol (2002 May) 12018980 Exiting the NIEHS site 2002 
Effect of the O6 substituent on misincorporation kinetics catalyzed by DNA polymerases at O(6)-methy ...   Woodside, Adrienne M; Guengerich, F Peter R01ES010546, T32ES007028 Biochemistry (2002 Jan 22) 11790127 Exiting the NIEHS site 2002 
EPR study of substrate binding to the Mn(II) active site of the bacterial antibiotic resistance enzy ...   Smoukov, Stoyan K; Telser, Joshua; Bernat, Bryan A; Rife, Chris L; Armstrong, Richard N; Hoffma ... T32ES007028 J Am Chem Soc (2002 Mar 13) 11878987 Exiting the NIEHS site 2002 
In vivo and in vitro hepatotoxicity and glutathione interactions of N-methyldithiocarbamate and N,N- ...   Thompson, Rodney W; Valentine, Holly L; Valentine, William M T32ES007028 Toxicol Sci (2002 Dec) 12441372 Exiting the NIEHS site 2002 
Local protein dynamics and catalysis: detection of segmental motion associated with rate-limiting pr ...   Codreanu, Simona G; Ladner, Jane E; Xiao, Gaoyi; Stourman, Nina V; Hachey, David L; Gilliland, ... T32ES007028 Biochemistry (2002 Dec 24) 12484753 Exiting the NIEHS site 2002 
Microsomal oxidation of tribromoethylene and reactions of tribromoethylene oxide.   Yoshioka, Tadao; Krauser, Joel A; Guengerich, F Peter R01ES010546, T32ES007028 Chem Res Toxicol (2002 Nov) 12437332 Exiting the NIEHS site 2002 
Misincorporation and stalling at O(6)-methylguanine and O(6)-benzylguanine: evidence for inactive po ...   Woodside, Adrienne M; Guengerich, F Peter R01ES010546, T32ES007028 Biochemistry (2002 Jan 22) 11790128 Exiting the NIEHS site 2002 
Molecular recognition at the dimer interface of a class mu glutathione transferase: role of a hydrop ...   Hornby, Judith A T; Codreanu, Simona G; Armstrong, Richard N; Dirr, Heini W T32ES007028 Biochemistry (2002 Dec 03) 12450388 Exiting the NIEHS site 2002 
Paradoxical enhancement of the toxicity of 1,2-dibromoethane by O6-alkylguanine-DNA alkyltransferase ...   Liu, Liping; Pegg, Anthony E; Williams, Kevin M; Guengerich, F Peter R01ES010546, T32ES007028 J Biol Chem (2002 Oct 04) 12151404 Exiting the NIEHS site 2002 
Reaction of aflatoxin B(1) oxidation products with lysine.   Guengerich, F Peter; Arneson, Kyle O; Williams, Kevin M; Deng, Zhengwu; Harris, Thomas M R01ES010546, T32ES007028 Chem Res Toxicol (2002 Jun) 12067245 Exiting the NIEHS site 2002 
Structure of the aflatoxin B(1) dialdehyde adduct formed from reaction with methylamine.   Guengerich, F Peter; Voehler, Markus; Williams, Kevin M; Deng, Zhengwu; Harris, Thomas M R01ES010546, T32ES007028 Chem Res Toxicol (2002 Jun) 12067246 Exiting the NIEHS site 2002 
Characterization of nucleoside and DNA adducts formed by S-(1-acetoxymethyl)glutathione and implicat ...   Marsch, G A; Mundkowski, R G; Morris, B J; Manier, M L; Hartman, M K; Guengerich, F P T32ES007028 Chem Res Toxicol (2001 May) 11368561 Exiting the NIEHS site 2001 
Characterization of the glycosylation sites in cyclooxygenase-2 using mass spectrometry.   Nemeth, J F; Hochgesang Jr, G P; Marnett, L J; Caprioli, R M; Hochensang Jr, G P T32ES007028 Biochemistry (2001 Mar 13) 11258925 Exiting the NIEHS site 2001 
Coumarin substrates for cytochrome P450 2D6 fluorescence assays.   Nakamura, K; Hanna, I H; Cai, H; Nishimura, Y; Williams, K M; Guengerich, F P T32ES007028 Anal Biochem (2001 May 15) 11355862 Exiting the NIEHS site 2001 
Cysteine and mercapturate conjugates of oxidized dopamine are in human striatum but only the cystein ...   Sidell, K R; Olson, S J; Ou, J J; Zhang, Y; Amarnath, V; Montine, T J T32ES007028 J Neurochem (2001 Nov) 11701754 Exiting the NIEHS site 2001 
Diversity in mechanisms of substrate oxidation by cytochrome P450 2D6. Lack of an allosteric role of ...   Hanna, I H; Krauser, J A; Cai, H; Kim, M S; Guengerich, F P T32ES007028 J Biol Chem (2001 Oct 26) 11509577 Exiting the NIEHS site 2001 
Dopamine thioethers in neurodegeneration.   Sidell, K R; Amamath, V; Montine, T J T32ES007028 Curr Top Med Chem (2001 Dec) 11895128 Exiting the NIEHS site 2001 
Elementary steps in the acquisition of Mn2+ by the fosfomycin resistance protein (FosA).   Bernat, B A; Armstrong, R N T32ES007028 Biochemistry (2001 Oct 23) 11601996 Exiting the NIEHS site 2001 
Heparin-binding histidine and lysine residues of rat selenoprotein P.   Hondal, R J; Ma, S; Caprioli, R M; Hill, K E; Burk, R F T32ES007028 J Biol Chem (2001 May 11) 11278668 Exiting the NIEHS site 2001 
Kinetic analysis of the slow ionization of glutathione by microsomal glutathione transferase MGST1.   Morgenstern, R; Svensson, R; Bernat, B A; Armstrong, R N T32ES007028 Biochemistry (2001 Mar 20) 11258959 Exiting the NIEHS site 2001 
Kinetic products of linoleate peroxidation: rapid beta-fragmentation of nonconjugated peroxyls.   Tallman, K A; Pratt, D A; Porter, N A T32ES007028 J Am Chem Soc (2001 Nov 28) 11716752 Exiting the NIEHS site 2001 
Mutagenicity of the malondialdehyde oligomerization products 2-(3'-oxo-1'-propenyl)-malondialdehyde ...   Riggins, J N; Marnett, L J T32ES007028 Mutat Res (2001 Oct 18) 11525918 Exiting the NIEHS site 2001 
Separation and identification of phospholipid peroxidation products.   Milne, G L; Porter, N A T32ES007028 Lipids (2001 Nov) 11795860 Exiting the NIEHS site 2001 
Disulfiram produces a non-carbon disulfide-dependent schwannopathy in the rat.   Tonkin, E G; Erve, J C; Valentine, W M T32ES007028 J Neuropathol Exp Neurol (2000 Sep) 11005259 Exiting the NIEHS site 2000 
p53 regulation of G(2) checkpoint is retinoblastoma protein dependent.   Flatt, P M; Tang, L J; Scatena, C D; Szak, S T; Pietenpol, J A T32ES007028 Mol Cell Biol (2000 Jun) 10825186 Exiting the NIEHS site 2000 
Replication of a site-specific trans-8,9-dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B(1) adduct by the ...   Johnston, D S; Stone, M P T32ES007028 Chem Res Toxicol (2000 Nov) 11087438 Exiting the NIEHS site 2000 
Effects of nitric oxide and nitric oxide-derived species on prostaglandin endoperoxide synthase and ...   Goodwin, D C; Landino, L M; Marnett, L J T32ES007028 FASEB J (1999 Jul) 10385604 Exiting the NIEHS site 1999 
Elucidation of a monovalent cation dependence and characterization of the divalent cation binding si ...   Bernat, B A; Laughlin, L T; Armstrong, R N T32ES007028 Biochemistry (1999 Jun 8) 10360943 Exiting the NIEHS site 1999 
Explanation of pre-steady-state kinetics and decreased burst amplitude of HIV-1 reverse transcriptas ...   Furge, L L; Guengerich, F P T32ES007028 Biochemistry (1999 Apr 13) 10200170 Exiting the NIEHS site 1999 
Failure of selenomethionine residues in albumin and immunoglobulin G to protect against peroxynitrit ...   Hondal, R J; Motley, A K; Hill, K E; Burk, R F T32ES007028 Arch Biochem Biophys (1999 Nov 1) 10525286 Exiting the NIEHS site 1999 
Flavodoxin as a model for the P450-interacting domain of NADPH cytochrome P450 reductase.   Jenkins, C M; Waterman, M R T32ES007028 Drug Metab Rev (1999 Feb) 10065372 Exiting the NIEHS site 1999 
Kinetics of cytochrome P450 2E1-catalyzed oxidation of ethanol to acetic acid via acetaldehyde.   Bell-Parikh, L C; Guengerich, F P T32ES007028 J Biol Chem (1999 Aug 20) 10446146 Exiting the NIEHS site 1999 
Reactions of prostaglandin endoperoxide synthase with nitric oxide and peroxynitrite.   Goodwin, D C; Landino, L M; Marnett, L J T32ES007028 Drug Metab Rev (1999 Feb) 10065376 Exiting the NIEHS site 1999 
Expression of eukaryotic cytochromes P450 in E. coli.   Jenkins, C M; Pikuleva, I; Waterman, M R T32ES007028 Methods Mol Biol (1998) 14577229 Exiting the NIEHS site 1998 
Mechanism of microsomal epoxide hydrolase. Semifunctional site-specific mutants affecting the alkyla ...   Laughlin, L T; Tzeng, H F; Lin, S; Armstrong, R N T32ES007028 Biochemistry (1998 Mar 3) 9485441 Exiting the NIEHS site 1998 
Mechanistic imperative for the evolution of a metalloglutathione transferase of the vicinal oxygen c ...   Laughlin, L T; Bernat, B A; Armstrong, R N T32ES007028 Chem Biol Interact (1998 Apr 24) 9679542 Exiting the NIEHS site 1998 
Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and Taxol-induced growth arres ...   Scatena, C D; Stewart, Z A; Mays, D; Tang, L J; Keefer, C J; Leach, S D; Pietenpol, J A T32ES007028 J Biol Chem (1998 Nov 13) 9804855 Exiting the NIEHS site 1998 
NADPH-flavodoxin reductase and flavodoxin from Escherichia coli: characteristics as a soluble micros ...   Jenkins, C M; Waterman, M R T32ES007028 Biochemistry (1998 Apr 28) 9558349 Exiting the NIEHS site 1998 
Pre-steady-state kinetics of nucleotide insertion following 8-oxo-7,8-dihydroguanine base pair misma ...   Furge, L L; Guengerich, F P T32ES007028 Biochemistry (1998 Mar 10) 9521678 Exiting the NIEHS site 1998 
Release of carbon disulfide is a contributing mechanism in the axonopathy produced by N,N-diethyldit ...   Johnson, D J; Graham, D G; Amarnath, V; Amarnath, K; Valentine, W M T32ES007028 Toxicol Appl Pharmacol (1998 Feb) 9473537 Exiting the NIEHS site 1998 
Twenty years of biochemistry of human P450s: purification, expression, mechanism, and relevance to d ...   Guengerich, F P; Hosea, N A; Parikh, A; Bell-Parikh, L C; Johnson, W W; Gillam, E M; Shimada, ... T32ES007028 Drug Metab Dispos (1998 Dec) 9860923 Exiting the NIEHS site 1998 
Analysis of nucleotide insertion and extension at 8-oxo-7,8-dihydroguanine by replicative T7 polymer ...   Furge, L L; Guengerich, F P T32ES007028 Biochemistry (1997 May 27) 9174365 Exiting the NIEHS site 1997 
Escherichia coli flavodoxin sepharose as an affinity resin for cytochromes P450 and use to identify ...   Jenkins, C M; Pikuleva, I; Kagawa, N; Waterman, M R T32ES007028 Arch Biochem Biophys (1997 Nov 1) 9344469 Exiting the NIEHS site 1997 
Fosfomycin resistance protein (FosA) is a manganese metalloglutathione transferase related to glyoxa ...   Bernat, B A; Laughlin, L T; Armstrong, R N T32ES007028 Biochemistry (1997 Mar 18) 9115979 Exiting the NIEHS site 1997 
Mutational analysis of the role of the distal histidine and glutamine residues of prostaglandin-endo ...   Landino, L M; Crews, B C; Gierse, J K; Hauser, S D; Marnett, L J T32ES007028 J Biol Chem (1997 Aug 22) 9261177 Exiting the NIEHS site 1997 
Repair of propanodeoxyguanosine by nucleotide excision repair in vivo and in vitro.   Johnson, K A; Fink, S P; Marnett, L J T32ES007028 J Biol Chem (1997 Apr 25) 9111054 Exiting the NIEHS site 1997 
Effects of cysteine-to-serine mutations on structural and functional properties of prostaglandin end ...   Smith, C J; Marnett, L J T32ES007028 Arch Biochem Biophys (1996 Nov 15) 8914931 Exiting the NIEHS site 1996 
Identification of retained N-formylmethionine in bacterial recombinant mammalian cytochrome P450 pro ...   Dong, M S; Bell, L C; Guo, Z; Phillips, D R; Blair, I A; Guengerich, F P T32ES007028 Biochemistry (1996 Aug 6) 8756465 Exiting the NIEHS site 1996 
Multiple forms of selenoprotein P in rat plasma.   Chittum, H S; Himeno, S; Hill, K E; Burk, R F T32ES007028 Arch Biochem Biophys (1996 Jan 1) 8554336 Exiting the NIEHS site 1996 
Peroxynitrite, the coupling product of nitric oxide and superoxide, activates prostaglandin biosynth ...   Landino, L M; Crews, B C; Timmons, M D; Morrow, J D; Marnett, L J T32ES007028 Proc Natl Acad Sci U S A (1996 Dec 24) 8986765 Exiting the NIEHS site 1996 
Steady-state and pre-steady-state kinetic analysis of dNTP insertion opposite 8-oxo-7,8-dihydroguani ...   Lowe, L G; Guengerich, F P T32ES007028 Biochemistry (1996 Jul 30) 8703958 Exiting the NIEHS site 1996 
The measurement of 2-thiothiazolidine-4-carboxylic acid as an index of the in vivo release of CS2 by ...   Johnson, D J; Graham, D G; Amarnath, V; Amarnath, K; Valentine, W M T32ES007028 Chem Res Toxicol (1996 Jul-Aug) 8828929 Exiting the NIEHS site 1996 
Developmentally regulated expression of adrenal 17 alpha-hydroxylase cytochrome P450 in the mouse em ...   Keeney, D S; Jenkins, C M; Waterman, M R T32ES007028 Endocrinology (1995 Nov) 7588219 Exiting the NIEHS site 1995 
Expression of cytochrome P450 2D6 in Escherichia coli, purification, and spectral and catalytic char ...   Gillam, E M; Guo, Z; Martin, M V; Jenkins, C M; Guengerich, F P T32ES007028 Arch Biochem Biophys (1995 Jun 01) 7786040 Exiting the NIEHS site 1995 
Liver and kidney necrosis in selenium-deficient rats depleted of glutathione.   Burk, R F; Hill, K E; Awad, J A; Morrow, J D; Lyons, P R T32ES007028 Lab Invest (1995 Jun) 7783430 Exiting the NIEHS site 1995 
Oxidation of benzo[a]pyrene by recombinant human cytochrome P450 enzymes.   Bauer, E; Guo, Z; Ueng, Y F; Bell, L C; Zeldin, D; Guengerich, F P T32ES007028 Chem Res Toxicol (1995 Jan-Feb) 7703357 Exiting the NIEHS site 1995 
Pathogenesis of diquat-induced liver necrosis in selenium-deficient rats: assessment of the roles of ...   Burk, R F; Hill, K E; Awad, J A; Morrow, J D; Kato, T; Cockell, K A; Lyons, P R T32ES007028 Hepatology (1995 Feb) 7843731 Exiting the NIEHS site 1995 
Refined solution structure of 8,9-dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B1 opposite CpA in the co ...   Johnston, D S; Stone, M P T32ES007028 Biochemistry (1995 Oct 31) 7578001 Exiting the NIEHS site 1995 
The chemistry of lipid alkoxyl radicals and their role in metal-amplified lipid peroxidation.   Marnett, L J; Wilcox, A L T32ES007028 Biochem Soc Symp (1995) 8660404 Exiting the NIEHS site 1995 
Detection and localization of lipid peroxidation in selenium- and vitamin E-deficient rats using F2- ...   Awad, J A; Morrow, J D; Hill, K E; Roberts 2nd, L J; Burk, R F T32ES007028 J Nutr (1994 Jun) 8207538 Exiting the NIEHS site 1994 
Detection of the major urinary metabolite of prostaglandin D2 in the circulation: demonstration of e ...   Awad, J A; Morrow, J D; Roberts 2nd, L J T32ES007028 J Allergy Clin Immunol (1994 May) 8182221 Exiting the NIEHS site 1994 
Effect of selenium deficiency and glutathione-modulating agents on diquat toxicity and lipid peroxid ...   Awad, J A; Burk, R F; Roberts 2nd, L J T32ES007028 J Pharmacol Exp Ther (1994 Sep) 7932197 Exiting the NIEHS site 1994 
Flavodoxin and NADPH-flavodoxin reductase from Escherichia coli support bovine cytochrome P450c17 hy ...   Jenkins, C M; Waterman, M R T32ES007028 J Biol Chem (1994 Nov 04) 7961651 Exiting the NIEHS site 1994 
Mechanisms of formation of 1,N6-ethenoadenine, 3,N4-ethenocytosine, 1,N2-ethenoguanine and N2,3-ethe ...   Persmark, M; Humphreys, W G; Okazaki, O; Raney, V M; Guengerich, F P T32ES007028 IARC Sci Publ (1994) 7806335 Exiting the NIEHS site 1994 
Spectroscopic and thermodynamic characterization of the interaction of N7-guanyl thioether derivativ ...   Persmark, M; Guengerich, F P T32ES007028 Biochemistry (1994 Jul 26) 8038155 Exiting the NIEHS site 1994 
Formation of 1,N2- and N2,3-ethenoguanine from 2-halooxiranes: isotopic labeling studies and isolati ...   Guengerich, F P; Persmark, M; Humphreys, W G T32ES007028 Chem Res Toxicol (1993 Sep-Oct) 8292741 Exiting the NIEHS site 1993 
Identification of non-cyclooxygenase-derived prostanoid (F2-isoprostane) metabolites in human urine ...   Awad, J A; Morrow, J D; Takahashi, K; Roberts 2nd, L J T32ES007028 J Biol Chem (1993 Feb 25) 8440704 Exiting the NIEHS site 1993 
N-nitroso-N-methylvinylamine: reaction of the epoxide with guanyl and adenyl moieties to yield adduc ...   Okazaki, O; Persmark, M; Guengerich, F P T32ES007028 Chem Res Toxicol (1993 Mar-Apr) 8477007 Exiting the NIEHS site 1993 
Polyunsaturated fatty acid alkoxyl radicals exist as carbon-centered epoxyallylic radicals: a key st ...   Wilcox, A L; Marnett, L J T32ES007028 Chem Res Toxicol (1993 Jul-Aug) 8374035 Exiting the NIEHS site 1993 
Simplification of the mass spectrometric assay for the major urinary metabolite of prostaglandin D2.   Awad, J A; Morrow, J D; Roberts 2nd, L J T32ES007028 J Chromatogr (1993 Jul 23) 8376525 Exiting the NIEHS site 1993 
Site-directed mutagenesis of the NH2 terminus of T4 endonuclease V. The position of the alpha NH2 mo ...   Schrock 3rd, R D; Lloyd, R S T32ES007028 J Biol Chem (1993 Jan 15) 8419366 Exiting the NIEHS site 1993 
Elucidation of catalytic specificities of human cytochrome P450 and glutathione S-transferase enzyme ...   Guengerich, F P; Shimada, T; Raney, K D; Yun, C H; Meyer, D J; Ketterer, B; Harris, T M; Groo ... T32ES007028 Environ Health Perspect (1992 Nov) 1486866 Exiting the NIEHS site 1992 
Formation of novel non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in carbon tetrachloride ...   Morrow, J D; Awad, J A; Kato, T; Takahashi, K; Badr, K F; Roberts 2nd, L J; Burk, R F T32ES007028 J Clin Invest (1992 Dec) 1469101 Exiting the NIEHS site 1992 
A 1H NMR probe for mobility in the reactive center loops of serpins: spin-echo studies of native and ...   Hood, D B; Gettins, P T32ES007028 Biochemistry (1991 Sep 17) 1892818 Exiting the NIEHS site 1991 
Reductive methylation of the amino terminus of endonuclease V eradicates catalytic activities. Evide ...   Schrock 3rd, R D; Lloyd, R S T32ES007028 J Biol Chem (1991 Sep 15) 1894643 Exiting the NIEHS site 1991 
Selective metal binding to Cys-78 within endonuclease V causes an inhibition of catalytic activities ...   Prince, M A; Friedman, B; Gruskin, E A; Schrock 3rd, R D; Lloyd, R S T32ES007028 J Biol Chem (1991 Jun 05) 2037608 Exiting the NIEHS site 1991 
Biological significance of facilitated diffusion in protein-DNA interactions. Applications to T4 end ...   Dowd, D R; Lloyd, R S T32ES007028 J Biol Chem (1990 Feb 25) 2406255 Exiting the NIEHS site 1990 
Formation of thiol conjugates of 9-deoxy-delta 9,delta 12(E)-prostaglandin D2 and delta 12(E)-prosta ...   Atsmon, J; Sweetman, B J; Baertschi, S W; Harris, T M; Roberts 2nd, L J T32ES007028 Biochemistry (1990 Apr 17) 2340271 Exiting the NIEHS site 1990 
Biological consequences of a reduction in the non-target DNA scanning capacity of a DNA repair enzym ...   Dowd, D R; Lloyd, R S T32ES007028 J Mol Biol (1989 Aug 20) 2681789 Exiting the NIEHS site 1989 
Carcinogen-nucleic acid interactions: equilibrium binding studies of aflatoxin B1 with the oligodeox ...   Gopalakrishnan, S; Byrd, S; Stone, M P; Harris, T M T32ES007028 Biochemistry (1989 Jan 24) 2496751 Exiting the NIEHS site 1989 
Expression of a human liver cytochrome P-450 protein with tolbutamide hydroxylase activity in Saccha ...   Brian, W R; Srivastava, P K; Umbenhauer, D R; Lloyd, R S; Guengerich, F P T32ES007028 Biochemistry (1989 Jun 13) 2669966 Exiting the NIEHS site 1989 
Mechanistic aspects of the dithiocarbamate-induced mobilization of cadmium.   Topping, R J; Jones, M M; Gale, G R; Smith, A B T32ES007028 J Inorg Biochem (1989 Jun) 2547894 Exiting the NIEHS site 1989 
Site-directed mutagenesis of the T4 endonuclease V gene: the role of arginine-3 in the target search ...   Dowd, D R; Lloyd, R S T32ES007028 Biochemistry (1989 Oct 31) 2690947 Exiting the NIEHS site 1989 
Non-Watson-Crick structures in oligodeoxynucleotides: self-association of d(TpCpGpA) stabilized at a ...   Topping, R J; Stone, M P; Brush, C K; Harris, T M T32ES007028 Biochemistry (1988 Sep 20) 3207671 Exiting the NIEHS site 1988 
Verrucofortine, a major metabolite of Penicillium verrucosum var. cyclopium, the fungus that produce ...   Hodge, R P; Harris, C M; Harris, T M T32ES007028 J Nat Prod (1988 Jan-Feb) 3373229 Exiting the NIEHS site 1988 
Activation of dihaloalkanes by glutathione conjugation and formation of DNA adducts.   Guengerich, F P; Peterson, L A; Cmarik, J L; Koga, N; Inskeep, P B T32ES007028 Environ Health Perspect (1987 Dec) 3329096 Exiting the NIEHS site 1987 
Efficient screening of recombinant DNA junctions afforded by probing with synthetic "bridge" oligonu ...   Recinos 3rd, A; Lloyd, R S T32ES007028 Biochem Biophys Res Commun (1986 Jul 31) 3017346 Exiting the NIEHS site 1986 
A convenient assay for mephenytoin 4-hydroxylase activity of human liver microsomal cytochrome P-450 ...   Shimada, T; Shea, J P; Guengerich, F P T32ES007028 Anal Biochem (1985 May 15) 4025815 Exiting the NIEHS site 1985 
Characterization of the enzymatic and nonenzymatic peroxidative degradation of iron porphyrins and c ...   Schaefer, W H; Harris, T M; Guengerich, F P T32ES007028 Biochemistry (1985 Jun 18) 3927975 Exiting the NIEHS site 1985 
Phosphorylation of DNA topoisomerase II by casein kinase II: modulation of eukaryotic topoisomerase ...   Ackerman, P; Glover, C V; Osheroff, N T32ES007028 Proc Natl Acad Sci U S A (1985 May) 2987912 Exiting the NIEHS site 1985 
Glutathione-mediated binding of dibromoalkanes to DNA: specificity of rat glutathione-S-transferases ...   Inskeep, P B; Guengerich, F P T32ES007028 Carcinogenesis (1984 Jun) 6373044 Exiting the NIEHS site 1984 
Toxicology of thiono-sulfur compounds.   Neal, R A; Halpert, J T32ES007028 Annu Rev Pharmacol Toxicol (1982) 7044288 Exiting the NIEHS site 1982 
Cytochrome P-450-dependent metabolism of 1,1,2,2-tetrachloroethane to dichloroacetic acid in vitro.   Halpert, J; Neal, R A T32ES007028 Biochem Pharmacol (1981 Jun 01) 7271831 Exiting the NIEHS site 1981 
Identification of the major protein adduct formed in rat liver after thioacetamide administration.   Dyroff, M C; Neal, R A T32ES007028 Cancer Res (1981 Sep) 6790164 Exiting the NIEHS site 1981 
Inactivation of rat liver cytochrome P-450 by the suicide substrates parathion and chloramphenicol.   Halpert, J; Neal, R A T32ES007028 Drug Metab Rev (1981) 7040015 Exiting the NIEHS site 1981 
Mutagenicity testing of 2,3,7,8-tetrachlordibenzo-p-dioxin in histidine auxotrophs of Salmonella typ ...   Geiger, L E; Neal, R A T32ES007028 Toxicol Appl Pharmacol (1981 Jun 15) 7020158 Exiting the NIEHS site 1981 
Syncytiotrophoblast membrane vesicles: a model for examining the human placental cholinergic system.   Fant, M E; Harbison, R D T32ES007028 Teratology (1981 Oct) 7336361 Exiting the NIEHS site 1981 
Tissue distribution, excretion, and metabolism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the ...   Olson, J R; Gasiewicz, T A; Neal, R A T32ES007028 Toxicol Appl Pharmacol (1980 Oct) 7444968 Exiting the NIEHS site 1980 
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