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Your Environment. Your Health.

Who We Fund: Publication Detail

Project Title: TRAINING GRANT IN MOLECULAR MECHANISMS OF TOXICITY
PI: Liu, Xiaoqi
Institution: University Of Kentucky
Grant Number: T32ES007266

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 146 publications
Export to Excel (http://www.niehs.nih.gov//portfolio/index.cfm/portfolio/grantpubdetail/grant_number/T32ES007266/format/excel)
Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Evaluation of antioxidant network proteins as novel prognostic biomarkers for head and neck cancer p ...   Wicker, Christina A; Takiar, Vinita; Suganya, Rangaswamy; Arnold, Susanne M; Brill, Yolanda M; ... T32ES007266 Oral Oncol (2020 12) 32801084 Exiting the NIEHS site 2020 
FUS regulates autophagy by mediating the transcription of genes critical to the autophagosome format ...   Arenas, Alexandra; Kuang, Lisha; Zhang, Jiayu; Kingren, Meagan S; Zhu, Haining T32ES007266 J Neurochem (2020 Dec 22) 33354770 Exiting the NIEHS site 2020 
Targeting PI3K and AMPKα Signaling Alone or in Combination to Enhance Radiosensitivity of Triple Neg ...   Johnson, Jeremy; Chow, Zeta; Napier, Dana; Lee, Eun; Weiss, Heidi L; Evers, B Mark; Rychahou, ... T32ES007266 Cells (2020 05 19) 32438621 Exiting the NIEHS site 2020 
De Novo Fatty Acid Synthesis-Driven Sphingolipid Metabolism Promotes Metastatic Potential of Colorec ...   Jafari, Naser; Drury, James; Morris, Andrew J; Onono, Fredrick O; Stevens, Payton D; Gao, Tian ... T32ES007266 Mol Cancer Res (2019 01) 30154249 Exiting the NIEHS site 2019 
Induction of AMPK activation by N,N'-diarylurea FND-4b decreases growth and increases apoptosis in t ...   Johnson, Jeremy; Rychahou, Piotr; Sviripa, Vitaliy M; Weiss, Heidi L; Liu, Chunming; Watt, Dav ... T32ES007266 PLoS One (2019) 30875375 Exiting the NIEHS site 2019 
ALS mutations of FUS suppress protein translation and disrupt the regulation of nonsense-mediated de ...   Kamelgarn, Marisa; Chen, Jing; Kuang, Lisha; Jin, Huan; Kasarskis, Edward J; Zhu, Haining T32ES007266 Proc Natl Acad Sci U S A (2018 12 18) 30455313 Exiting the NIEHS site 2018 
Hematopoietic Stem Cells: Normal Versus Malignant.   Carroll, Dustin; St Clair, Daret K T32ES007266 Antioxid Redox Signal (2018 12 01) 29084438 Exiting the NIEHS site 2018 
A novel redox regulator, MnTnBuOE-2-PyP5+, enhances normal hematopoietic stem/progenitor cell functi ...   Zhao, Y; Carroll, D W; You, Y; Chaiswing, L; Wen, R; Batinic-Haberle, I; Bondada, S; Liang, ... T32ES007266 Redox Biol (2017 08) 28231483 Exiting the NIEHS site 2017 
Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metast ...   Burikhanov, Ravshan; Hebbar, Nikhil; Noothi, Sunil K; Shukla, Nidhi; Sledziona, James; Araujo, ... T32ES007266 Cell Rep (2017 01 10) 28076793 Exiting the NIEHS site 2017 
Clinical and experimental studies of a novel P525R FUS mutation in amyotrophic lateral sclerosis.   Kuang, Lisha; Kamelgarn, Marisa; Arenas, Alexandra; Gal, Jozsef; Taylor, Deborah; Gong, Weimin ... T32ES007266 Neurol Genet (2017 Aug) 28812062 Exiting the NIEHS site 2017 
Inorganic arsenic inhibits the nucleotide excision repair pathway and reduces the expression of XPC.   Holcomb, Nathaniel; Goswami, Mamta; Han, Sung Gu; Scott, Tim; D'Orazio, John; Orren, David K; ... T32ES007266 DNA Repair (Amst) (2017 04) 28237621 Exiting the NIEHS site 2017 
MutSβ abundance and Msh3 ATP hydrolysis activity are important drivers of CTG•CAG repeat expansions.   Keogh, Norma; Chan, Kara Y; Li, Guo-Min; Lahue, Robert S T32ES007266 Nucleic Acids Res (2017 Sep 29) 28973443 Exiting the NIEHS site 2017 
Noninvasive liquid diet delivery of stable isotopes into mouse models for deep metabolic network tra ...   Sun, Ramon C; Fan, Teresa W-M; Deng, Pan; Higashi, Richard M; Lane, Andrew N; Le, Anh-Thu; Sco ... T32ES007266 Nat Commun (2017 11 21) 29158483 Exiting the NIEHS site 2017 
Polyubiquitination of apurinic/apyrimidinic endonuclease 1 by Parkin.   Scott, Timothy L; Wicker, Christina A; Suganya, Rangaswamy; Dhar, Bithika; Pittman, Thomas; Hor ... T32ES007266 Mol Carcinog (2017 02) 27148961 Exiting the NIEHS site 2017 
Quantitative profiling of carbonyl metabolites directly in crude biological extracts using chemosele ...   Deng, Pan; Higashi, Richard M; Lane, Andrew N; Bruntz, Ronald C; Sun, Ramon C; Ramakrishnam Raj ... T32ES007266 Analyst (2017 12 18) 29192912 Exiting the NIEHS site 2017 
Quercetin inhibits Cr(VI)-induced malignant cell transformation by targeting miR-21-PDCD4 signaling ...   Pratheeshkumar, Poyil; Son, Young-Ok; Divya, Sasidharan Padmaja; Wang, Lei; Turcios, Lilia; Roy ... T32ES007266 Oncotarget (2017 Aug 08) 28881718 Exiting the NIEHS site 2017 
Analysis of RNA expression of normal and cancer tissues reveals high correlation of COP9 gene expres ...   Wicker, Christina A; Izumi, Tadahide T32ES007266 BMC Genomics (2016 12 01) 27903243 Exiting the NIEHS site 2016 
Cancer Stem-Like Cells Accumulated in Nickel-Induced Malignant Transformation.   Wang, Lei; Fan, Jia; Hitron, John Andrew; Son, Young-Ok; Wise, James T F; Roy, Ram Vinod; Kim, ... T32ES007266 Toxicol Sci (2016 06) 26962057 Exiting the NIEHS site 2016 
Different roles of ROS and Nrf2 in Cr(VI)-induced inflammatory responses in normal and Cr(VI)-transf ...   Roy, Ram Vinod; Pratheeshkumar, Poyil; Son, Yong-Ok; Wang, Lei; Hitron, John Andrew; Divya, Sa ... T32ES007266 Toxicol Appl Pharmacol (2016 09 15) 27470422 Exiting the NIEHS site 2016 
Dioxin-like pollutants increase hepatic flavin containing monooxygenase (FMO3) expression to promote ...   Petriello, Michael C; Hoffman, Jessie B; Sunkara, Manjula; Wahlang, Banrida; Perkins, Jordan T; ... P42ES007380, T32ES007266 J Nutr Biochem (2016 07) 27155921 Exiting the NIEHS site 2016 
Exercise protects against PCB-induced inflammation and associated cardiovascular risk factors.   Murphy, Margaret O; Petriello, Michael C; Han, Sung Gu; Sunkara, Manjula; Morris, Andrew J; Ess ... P42ES007380, T32ES007266 Environ Sci Pollut Res Int (2016 Feb) 25586614 Exiting the NIEHS site 2016 
Exposure of Human Lung Cells to Tobacco Smoke Condensate Inhibits the Nucleotide Excision Repair Pat ...   Holcomb, Nathaniel; Goswami, Mamta; Han, Sung Gu; Clark, Samuel; Orren, David K; Gairola, C Ga ... T32ES007266 PLoS One (2016) 27391141 Exiting the NIEHS site 2016 
Hexavalent chromium induces malignant transformation of human lung bronchial epithelial cells via RO ...   Pratheeshkumar, Poyil; Son, Young-Ok; Divya, Sasidharan Padmaja; Turcios, Lilia; Roy, Ram Vinod ... T32ES007266 Oncotarget (2016 Aug 09) 27323401 Exiting the NIEHS site 2016 
Polychlorinated biphenyls and links to cardiovascular disease.   Perkins, Jordan T; Petriello, Michael C; Newsome, Bradley J; Hennig, Bernhard P42ES007380, T32ES007266 Environ Sci Pollut Res Int (2016 Feb) 25877901 Exiting the NIEHS site 2016 
Proteomic analysis of FUS interacting proteins provides insights into FUS function and its role in A ...   Kamelgarn, Marisa; Chen, Jing; Kuang, Lisha; Arenas, Alexandra; Zhai, Jianjun; Zhu, Haining; G ... T32ES007266 Biochim Biophys Acta (2016 10) 27460707 Exiting the NIEHS site 2016 
Simultaneous quantitation of oxidized and reduced glutathione via LC-MS/MS: An insight into the redo ...   Carroll, Dustin; Howard, Diana; Zhu, Haining; Paumi, Christian M; Vore, Mary; Bondada, Subbara ... T32ES007266 Free Radic Biol Med (2016 08) 27212018 Exiting the NIEHS site 2016 
Antioncogenic and Oncogenic Properties of Nrf2 in Arsenic-induced Carcinogenesis.   Son, Young-Ok; Pratheeshkumar, Poyil; Roy, Ram Vinod; Hitron, John Andrew; Wang, Lei; Divya, S ... T32ES007266 J Biol Chem (2015 Nov 06) 26385919 Exiting the NIEHS site 2015 
Blackberry extract inhibits UVB-induced oxidative damage and inflammation through MAP kinases and NF ...   Divya, Sasidharan Padmaja; Wang, Xin; Pratheeshkumar, Poyil; Son, Young-Ok; Roy, Ram Vinod; Kim ... T32ES007266 Toxicol Appl Pharmacol (2015 Apr 01) 25680589 Exiting the NIEHS site 2015 
Ethanol enhances arsenic-induced cyclooxygenase-2 expression via both NFAT and NF-κB signalings in c ...   Wang, Lei; Hitron, John Andrew; Wise, James T F; Son, Young-Ok; Roy, Ram Vinod; Kim, Donghern; ... T32ES007266 Toxicol Appl Pharmacol (2015 Oct 15) 26220687 Exiting the NIEHS site 2015 
Exposure to coplanar PCBs induces endothelial cell inflammation through epigenetic regulation of NF- ...   Liu, Dandan; Perkins, Jordan T; Petriello, Michael C; Hennig, Bernhard P42ES007380, T32ES007266 Toxicol Appl Pharmacol (2015 Dec 15) 26519613 Exiting the NIEHS site 2015 
Subcellular localization and RNAs determine FUS architecture in different cellular compartments.   Yang, Liuqing; Zhang, Jiayu; Kamelgarn, Marisa; Niu, Chunyan; Gal, Jozsef; Gong, Weimin; Zhu, ... T32ES007266 Hum Mol Genet (2015 Sep 15) 26123490 Exiting the NIEHS site 2015 
The DNA structure and sequence preferences of WRN underlie its function in telomeric recombination e ...   Edwards, Deanna N; Machwe, Amrita; Chen, Li; Bohr, Vilhelm A; Orren, David K T32ES007266 Nat Commun (2015 Sep 30) 26420422 Exiting the NIEHS site 2015 
Green tea diet decreases PCB 126-induced oxidative stress in mice by up-regulating antioxidant enzym ...   Newsome, Bradley J; Petriello, Michael C; Han, Sung Gu; Murphy, Margaret O; Eske, Katryn E; Sun ... P42ES007380, T32ES007266 J Nutr Biochem (2014 Feb) 24378064 Exiting the NIEHS site 2014 
Influence of nutrition in PCB-induced vascular inflammation.   Petriello, Michael C; Newsome, Bradley; Hennig, Bernhard P42ES007380, T32ES007266 Environ Sci Pollut Res Int (2014 May) 23417440 Exiting the NIEHS site 2014 
Intramolecular telomeric G-quadruplexes dramatically inhibit DNA synthesis by replicative and transl ...   Edwards, Deanna N; Machwe, Amrita; Wang, Zhigang; Orren, David K T32ES007266 PLoS One (2014) 24454683 Exiting the NIEHS site 2014 
Manganese superoxide dismutase-mediated inside-out signaling in HaCaT human keratinocytes and SKH-1 ...   Holley, Aaron K; Xu, Yong; Noel, Teresa; Bakthavatchalu, Vasudevan; Batinic-Haberle, Ines; St C ... T32ES007266 Antioxid Redox Signal (2014 May 20) 24635018 Exiting the NIEHS site 2014 
PKA-mediated phosphorylation of ATR promotes recruitment of XPA to UV-induced DNA damage.   Jarrett, Stuart G; Wolf Horrell, Erin M; Christian, Perry A; Vanover, Jillian C; Boulanger, Mar ... T32ES007266 Mol Cell (2014 Jun 19) 24950377 Exiting the NIEHS site 2014 
Redox-mediated and ionizing-radiation-induced inflammatory mediators in prostate cancer development ...   Miao, Lu; Holley, Aaron K; Zhao, Yanming; St Clair, William H; St Clair, Daret K T32ES007266 Antioxid Redox Signal (2014 Mar 20) 24093432 Exiting the NIEHS site 2014 
Redox-modulated phenomena and radiation therapy: the central role of superoxide dismutases.   Holley, Aaron K; Miao, Lu; St Clair, Daret K; St Clair, William H T32ES007266 Antioxid Redox Signal (2014 Apr 01) 24094070 Exiting the NIEHS site 2014 
Strand exchange of telomeric DNA catalyzed by the Werner syndrome protein (WRN) is specifically stim ...   Edwards, Deanna N; Orren, David K; Machwe, Amrita T32ES007266 Nucleic Acids Res (2014 Jul) 24880691 Exiting the NIEHS site 2014 
Apigenin suppresses migration and invasion of transformed cells through down-regulation of C-X-C che ...   Wang, Lei; Kuang, Lisha; Hitron, John Andrew; Son, Young-Ok; Wang, Xin; Budhraja, Amit; Lee, ... T32ES007266 Toxicol Appl Pharmacol (2013 Oct 01) 23743303 Exiting the NIEHS site 2013 
Coordinated processing of 3' slipped (CAG)n/(CTG)n hairpins by DNA polymerases β and δ preferentiall ...   Chan, Nelson L S; Guo, Jinzhen; Zhang, Tianyi; Mao, Guogen; Hou, Caixia; Yuan, Fenghua; Huang, ... T32ES007266 J Biol Chem (2013 May 24) 23585564 Exiting the NIEHS site 2013 
KEAP1 is a redox sensitive target that arbitrates the opposing radiosensitive effects of parthenolid ...   Xu, Yong; Fang, Fang; Miriyala, Sumitra; Crooks, Peter A; Oberley, Terry D; Chaiswing, Luksana ... T32ES007266 Cancer Res (2013 Jul 15) 23674500 Exiting the NIEHS site 2013 
Cadmium induces carcinogenesis in BEAS-2B cells through ROS-dependent activation of PI3K/AKT/GSK-3β/ ...   Son, Young-Ok; Wang, Lei; Poyil, Pratheeshkumar; Budhraja, Amit; Hitron, J Andrew; Zhang, Zhuo ... T32ES007266 Toxicol Appl Pharmacol (2012 Oct 15) 22884995 Exiting the NIEHS site 2012 
Casein kinase 2α regulates multidrug resistance-associated protein 1 function via phosphorylation of ...   Stolarczyk, Elzbieta I; Reiling, Cassandra J; Pickin, Kerry A; Coppage, Ryan; Knecht, Marc R; P ... T32ES007266 Mol Pharmacol (2012 Sep) 22695718 Exiting the NIEHS site 2012 
Ethanol enhances tumor angiogenesis in vitro induced by low-dose arsenic in colon cancer cells throu ...   Wang, Lei; Son, Young-Ok; Ding, Songze; Wang, Xin; Hitron, John Andrew; Budhraja, Amit; Lee, ... T32ES007266 Toxicol Sci (2012 Dec) 22872060 Exiting the NIEHS site 2012 
Manganese superoxide dismutase is a mitochondrial fidelity protein that protects Polγ against UV-ind ...   Bakthavatchalu, V; Dey, S; Xu, Y; Noel, T; Jungsuwadee, P; Holley, A K; Dhar, S K; Batinic-Ha ... T32ES007266 Oncogene (2012 Apr 26) 21909133 Exiting the NIEHS site 2012 
Manganese superoxide dismutase: beyond life and death.   Holley, Aaron K; Dhar, Sanjit Kumar; Xu, Yong; St Clair, Daret K T32ES007266 Amino Acids (2012 Jan) 20454814 Exiting the NIEHS site 2012 
Pigment-independent cAMP-mediated epidermal thickening protects against cutaneous UV injury by kerat ...   Scott, Timothy L; Christian, Perry A; Kesler, Melissa V; Donohue, Kevin M; Shelton, Brent; Waka ... T32ES007266 Exp Dermatol (2012 Oct) 23078399 Exiting the NIEHS site 2012 
Androgen regulation of epithelial-mesenchymal transition in prostate tumorigenesis.   Matuszak, Emily A; Kyprianou, Natasha T32ES007266 Expert Rev Endocrinol Metab (2011 May) 23667383 Exiting the NIEHS site 2011 
Cadmium induces autophagy through ROS-dependent activation of the LKB1-AMPK signaling in skin epider ...   Son, Young-Ok; Wang, Xin; Hitron, John Andrew; Zhang, Zhuo; Cheng, Senping; Budhraja, Amit; Di ... T32ES007266 Toxicol Appl Pharmacol (2011 Sep 15) 21767558 Exiting the NIEHS site 2011 
Differential gene expression in liver and small intestine from lactating rats compared to age-matche ...   Athippozhy, Antony; Huang, Liping; Wooton-Kee, Clavia Ruth; Zhao, Tianyong; Jungsuwadee, Paiboo ... T32ES007266 BMC Genomics (2011 Feb 03) 21291544 Exiting the NIEHS site 2011 
Manganese superoxide dismutase: guardian of the powerhouse.   Holley, Aaron K; Bakthavatchalu, Vasudevan; Velez-Roman, Joyce M; St Clair, Daret K T32ES007266 Int J Mol Sci (2011) 22072939 Exiting the NIEHS site 2011 
Mitochondrial superoxide dismutase--signals of distinction.   Miriyala, Sumitra; Holley, Aaron K; St Clair, Daret K T32ES007266 Anticancer Agents Med Chem (2011 Feb) 21355846 Exiting the NIEHS site 2011 
NADPH oxidase activation is required in reactive oxygen species generation and cell transformation i ...   Wang, Xin; Son, Young-Ok; Chang, Qingshan; Sun, Lijuan; Hitron, J Andrew; Budhraja, Amit; Zhan ... T32ES007266 Toxicol Sci (2011 Oct) 21742780 Exiting the NIEHS site 2011 
Regulation of ABC transporter function via phosphorylation by protein kinases.   Stolarczyk, Elzbieta I; Reiling, Cassandra J; Paumi, Christian M T32ES007266 Curr Pharm Biotechnol (2011 Apr) 21118091 Exiting the NIEHS site 2011 
The dual roles of c-Jun NH2-terminal kinase signaling in Cr(VI)-induced apoptosis in JB6 cells.   Son, Young-Ok; Hitron, John Andrew; Cheng, Senping; Budhraja, Amit; Zhang, Zhuo; Lan Guo, Nanc ... T32ES007266 Toxicol Sci (2011 Feb) 21047991 Exiting the NIEHS site 2011 
ABCG5/ABCG8-independent biliary cholesterol excretion in lactating rats.   Coy, Donna J; Wooton-Kee, Clavia R; Yan, Baoxiang; Sabeva, Nadezhda; Su, Kai; Graf, Gregory; V ... T32ES007266 Am J Physiol Gastrointest Liver Physiol (2010 Jul) 20413720 Exiting the NIEHS site 2010 
Cadmium induces intracellular Ca2+- and H2O2-dependent apoptosis through JNK- and p53-mediated pathw ...   Son, Young-Ok; Lee, Jeong-Chae; Hitron, J Andrew; Pan, Jingju; Zhang, Zhuo; Shi, Xianglin T32ES007266 Toxicol Sci (2010 Jan) 19887573 Exiting the NIEHS site 2010 
Mechanisms for increased expression of cholesterol 7alpha-hydroxylase (Cyp7a1) in lactating rats.   Wooton-Kee, Clavia Ruth; Coy, Donna J; Athippozhy, Antony T; Zhao, Tianyong; Jones, Brett R; Vo ... T32ES007266 Hepatology (2010 Jan) 19957370 Exiting the NIEHS site 2010 
In vitro skin diffusion study of pure forskolin versus a forskolin-containing Plectranthus barbatus ...   Chen, Jing; Hammell, Dana C; Spry, Malinda; D'Orazio, John A; Stinchcomb, Audra L T32ES007266 J Nat Prod (2009 Apr) 19281221 Exiting the NIEHS site 2009 
Manganese flux across the blood-brain barrier.   Yokel, Robert A T32ES007266 Neuromolecular Med (2009) 19902387 Exiting the NIEHS site 2009 
Stem cell factor rescues tyrosinase expression and pigmentation in discreet anatomic locations in al ...   Vanover, Jillian C; Spry, Malinda L; Hamilton, Laura; Wakamatsu, Kazumasa; Ito, Shosuke; D'Oraz ... T32ES007266 Pigment Cell Melanoma Res (2009 Dec) 19682281 Exiting the NIEHS site 2009 
Benzo[a]pyrene induces intercellular adhesion molecule-1 through a caveolae and aryl hydrocarbon rec ...   Oesterling, Elizabeth; Toborek, Michal; Hennig, Bernhard P42ES007380, T32ES007266 Toxicol Appl Pharmacol (2008 Oct 15) 18671994 Exiting the NIEHS site 2008 
Changing ratios of omega-6 to omega-3 fatty acids can differentially modulate polychlorinated biphen ...   Wang, Lei; Reiterer, Gudrun; Toborek, Michal; Hennig, Bernhard P42ES007380, T32ES007266 Chem Biol Interact (2008 Mar 10) 18155686 Exiting the NIEHS site 2008 
Effect of dietary selenium on the promotion of hepatocarcinogenesis by 3,3', 4,4'-tetrachlorobipheny ...   Stemm, Divinia N; Tharappel, Job C; Lehmler, Hans-Joachim; Srinivasan, Cidambi; Morris, J Steve ... P42ES007380, P42ES013661, T32ES007266 Exp Biol Med (Maywood) (2008 Mar) 18296742 Exiting the NIEHS site 2008 
Increased cholesterol 7alpha-hydroxylase expression and size of the bile acid pool in the lactating ...   Wooton-Kee, Clavia Ruth; Cohen, David E; Vore, Mary T32ES007266 Am J Physiol Gastrointest Liver Physiol (2008 Apr) 18292185 Exiting the NIEHS site 2008 
PRC1 associates with the hsp70i promoter and interacts with HSF2 during mitosis.   Murphy, Lynea A; Wilkerson, Donald C; Hong, Yiling; Sarge, Kevin D T32ES007266 Exp Cell Res (2008 Jul 1) 18570919 Exiting the NIEHS site 2008 
HSF1-TPR interaction facilitates export of stress-induced HSP70 mRNA.   Skaggs, Hollie S; Xing, Hongyan; Wilkerson, Donald C; Murphy, Lynea A; Hong, Yiling; Mayhew, C ... T32ES007266 J Biol Chem (2007 Nov 23) 17897941 Exiting the NIEHS site 2007 
HSF2 binds to the Hsp90, Hsp27, and c-Fos promoters constitutively and modulates their expression.   Wilkerson, Donald C; Skaggs, Hollie S; Sarge, Kevin D T32ES007266 Cell Stress Chaperones (2007) 17915561 Exiting the NIEHS site 2007 
Physiological fever temperature induces a protective stress response in T lymphocytes mediated by he ...   Murapa, Patience; Gandhapudi, Siva; Skaggs, Hollie S; Sarge, Kevin D; Woodward, Jerold G T32ES007266 J Immunol (2007 Dec 15) 18056375 Exiting the NIEHS site 2007 
Review of the pharmacology and clinical profile of bupropion, an antidepressant and tobacco use cess ...   Dwoskin, Linda P; Rauhut, Anthony S; King-Pospisil, Kelley A; Bardo, Michael T T32ES007266 CNS Drug Rev (2006 Fall-Winter) 17227286 Exiting the NIEHS site 2006 
Hormonal regulation of hepatic organic anion transporting polypeptides.   Wood, M; Ananthanarayanan, M; Jones, B; Wooton-Kee, R; Hoffman, T; Suchy, F J; Vore, M T32ES007266 Mol Pharmacol (2005 Jul) 15840840 Exiting the NIEHS site 2005 
Manganese distribution across the blood-brain barrier. IV. Evidence for brain influx through store-o ...   Crossgrove, Janelle S; Yokel, Robert A T32ES007266 Neurotoxicology (2005 Jun) 15935202 Exiting the NIEHS site 2005 
Modeling the effects of chronic toxicity on fish populations: the influence of life-history strategi ...   Spromberg, Julann A; Birge, Wesley J T32ES007266 Environ Toxicol Chem (2005 Jun) 16117134 Exiting the NIEHS site 2005 
Population survivorship index for fish and amphibians: application to criterion development and risk ...   Spromberg, Julann A; Birge, Wesley J T32ES007266 Environ Toxicol Chem (2005 Jun) 16117135 Exiting the NIEHS site 2005 
Role of arginine residues 14 and 15 in dictating DNA binding stability and transactivation of the ar ...   Wache, Susanne C; Hoagland, Erica M; Zeigler, Georgia; Swanson, Hollie I T32ES007266 Gene Expr (2005) 16358414 Exiting the NIEHS site 2005 
Role of P-glycoprotein in distribution of nelfinavir across the blood-mammary tissue barrier and blo ...   Edwards, Jeffrey E; Alcorn, Jane; Savolainen, Juoko; Anderson, Bradley D; McNamara, Patrick J T32ES007266 Antimicrob Agents Chemother (2005 Apr) 15793156 Exiting the NIEHS site 2005 
Estradiol represses prolactin-induced expression of Na+/taurocholate cotransporting polypeptide in l ...   Cao, Jingsong; Wood, Marcie; Liu, Yong; Hoffman, Tim; Hyde, Jim; Park-Sarge, Ok-Kyong; Vore, ... T32ES007266 Endocrinology (2004 Apr) 14684617 Exiting the NIEHS site 2004 
Manganese distribution across the blood-brain barrier III. The divalent metal transporter-1 is not t ...   Crossgrove, Janelle S; Yokel, Robert A T32ES007266 Neurotoxicology (2004 Mar) 15019308 Exiting the NIEHS site 2004 
Manganese toxicokinetics at the blood-brain barrier.   Yokel, Robert A; Crossgrove, Janelle S T32ES007266 Res Rep Health Eff Inst (2004 Jan) 15043400 Exiting the NIEHS site 2004 
Cell proliferation and apoptosis are altered in mice deficient in the NF-kappaB p50 subunit after tr ...   Tharappel, Job C; Nalca, Aysegul; Owens, Aaron B; Ghabrial, Leila; Konz, Elizabeth C; Glauert, ... T32ES007266 Toxicol Sci (2003 Oct) 12883078 Exiting the NIEHS site 2003 
Effect of a single dose of polychlorinated biphenyls on hepatic cell proliferation and the DNA bindi ...   Lu, Zijing; Tharappel, Job C; Lee, Eun Y; Robertson, Larry W; Spear, Brett T; Glauert, Howard ... P42ES007380, T32ES007266 Mol Carcinog (2003 Aug) 12891626 Exiting the NIEHS site 2003 
Hydromorphone transfer into breast milk after intranasal administration.   Edwards, Jeffrey E; Rudy, Anita C; Wermeling, Daniel P; Desai, Nirmala; McNamara, Patrick J T32ES007266 Pharmacotherapy (2003 Feb) 12587803 Exiting the NIEHS site 2003 
Manganese distribution across the blood-brain barrier. I. Evidence for carrier-mediated influx of ma ...   Crossgrove, Janelle S; Allen, David D; Bukaveckas, Bonny L; Rhineheimer, Susan S; Yokel, Robert ... T32ES007266 Neurotoxicology (2003 Jan) 12564377 Exiting the NIEHS site 2003 
Manganese distribution across the blood-brain barrier. II. Manganese efflux from the brain does not ...   Yokel, Robert A; Crossgrove, Janelle S; Bukaveckas, Bonny L T32ES007266 Neurotoxicology (2003 Jan) 12564378 Exiting the NIEHS site 2003 
Nick-dependent and -independent processing of large DNA loops in human cells.   McCulloch, Scott D; Gu, Liya; Li, Guo-Min T32ES007266 J Biol Chem (2003 Dec 12) 14522965 Exiting the NIEHS site 2003 
Phosphorylation of supernatant protein factor enhances its ability to stimulate microsomal squalene ...   Singh, Dev K; Mokashi, Vishwesh; Elmore, C Lee; Porter, Todd D T32ES007266 J Biol Chem (2003 Feb 21) 12454003 Exiting the NIEHS site 2003 
Effects of a P-glycoprotein inhibitor on brain and plasma concentrations of anti-human immunodeficie ...   Savolainen, Jouko; Edwards, Jeffrey E; Morgan, Michael E; McNamara, Patrick J; Anderson, Bradle ... T32ES007266 Drug Metab Dispos (2002 May) 11950774 Exiting the NIEHS site 2002 
GF120918, a P-glycoprotein modulator, increases the concentration of unbound amprenavir in the centr ...   Edwards, Jeffrey E; Brouwer, Kenneth R; McNamara, Patrick J T32ES007266 Antimicrob Agents Chemother (2002 Jul) 12069991 Exiting the NIEHS site 2002 
Modification of the nucleotide cofactor-binding site of cytochrome P-450 reductase to enhance turnov ...   Elmore, C Lee; Porter, Todd D T32ES007266 J Biol Chem (2002 Dec 13) 12381719 Exiting the NIEHS site 2002 
Peroxisome proliferators do not activate the transcription factors AP-1, early growth response-1, or ...   O'Brien, Michelle L; Cunningham, Michael L; Spear, Brett T; Glauert, Howard P T32ES007266 Toxicol Sci (2002 Sep) 12215668 Exiting the NIEHS site 2002 
Regulation of cell proliferation, apoptosis, and transcription factor activities during the promotio ...   Tharappel, Job C; Lee, Eun Y; Robertson, Larry W; Spear, Brett T; Glauert, Howard P P42ES007380, T32ES007266 Toxicol Appl Pharmacol (2002 Mar 15) 11906247 Exiting the NIEHS site 2002 
1,2-dithiole-3-thione and its structural analogue oltipraz are potent inhibitors of dibenz.   Smith, W A; Arif, J M; Gupta, R C T32ES007266 Int J Cancer (2001 Jan 01) 11149412 Exiting the NIEHS site 2001 
2,4,4'-trichlorobiphenyl increases STAT5 transcriptional activity.   Oakley, G G; Roe, A L; Blouin, R A; Twaroski, T P; Ganguly, T C; Vore, M; Lehmler, H J; Rober ... P42ES007380, T32ES007266 Mol Carcinog (2001 Apr) 11346882 Exiting the NIEHS site 2001 
Cytochrome P450 and antioxidant activity in interleukin-6 knockout mice after induction of the acute ...   Warren, G W; van Ess, P J; Watson, A M; Mattson, M P; Blouin, R A T32ES007266 J Interferon Cytokine Res (2001 Oct) 11710994 Exiting the NIEHS site 2001 
Differential activation of hepatic NF-kappaB in rats and hamsters by the peroxisome proliferators Wy ...   Tharappel, J C; Cunningham, M L; Spear, B T; Glauert, H P T32ES007266 Toxicol Sci (2001 Jul) 11399789 Exiting the NIEHS site 2001 
Effect of chemopreventive agents on DNA adduction induced by the potent mammary carcinogen dibenzo[a ...   Smith, W A; Freeman, J W; Gupta, R C T32ES007266 Mutat Res (2001 Sep 01) 11506803 Exiting the NIEHS site 2001 
Effects of peroxisome proliferators on antioxidant enzymes and antioxidant vitamins in rats and hams ...   O'Brien, M L; Twaroski, T P; Cunningham, M L; Glauert, H P; Spear, B T T32ES007266 Toxicol Sci (2001 Apr) 11248139 Exiting the NIEHS site 2001 
Effects of peroxisome proliferators on glutathione and glutathione-related enzymes in rats and hamst ...   O'Brien, M L; Cunningham, M L; Spear, B T; Glauert, H P T32ES007266 Toxicol Appl Pharmacol (2001 Feb 15) 11181109 Exiting the NIEHS site 2001 
Effects of selected polychlorinated biphenyl (PCB) congeners on hepatic glutathione, glutathione-rel ...   Twaroski, T P; O'Brien, M L; Robertson, L W T32ES007266 Biochem Pharmacol (2001 Aug 01) 11434900 Exiting the NIEHS site 2001 
Inhibition of human squalene monooxygenase by tellurium compounds: evidence of interaction with vici ...   Laden, B P; Porter, T D T32ES007266 J Lipid Res (2001 Feb) 11181753 Exiting the NIEHS site 2001 
Polychlorinated biphenyl-induced effects on metabolic enzymes, AP-1 binding, vitamin E, and oxidativ ...   Twaroski, T P; O'Brien, M L; Larmonier, N; Glauert, H P; Robertson, L W P42ES007380, T32ES007266 Toxicol Appl Pharmacol (2001 Mar 1) 11222084 Exiting the NIEHS site 2001 
PRL, placental lactogen, and GH induce NA(+)/taurocholate-cotransporting polypeptide gene expression ...   Cao, J; Gowri, P M; Ganguly, T C; Wood, M; Hyde, J F; Talamantes, F; Vore, M T32ES007266 Endocrinology (2001 Oct) 11564677 Exiting the NIEHS site 2001 
Regulation of heat shock transcription factor 1 by stress-induced SUMO-1 modification.   Hong, Y; Rogers, R; Matunis, M J; Mayhew, C N; Goodson, M L; Park-Sarge, O K; Sarge, K D; Goo ... T32ES007266 J Biol Chem (2001 Oct 26) 11514557 Exiting the NIEHS site 2001 
Sumo-1 modification regulates the DNA binding activity of heat shock transcription factor 2, a promy ...   Goodson, M L; Hong, Y; Rogers, R; Matunis, M J; Park-Sarge, O K; Sarge, K D T32ES007266 J Biol Chem (2001 May 25) 11278381 Exiting the NIEHS site 2001 
The effect of endotoxin on hepatocyte nuclear factor 1 nuclear protein binding: potential implicatio ...   Roe, A L; Poloyac, S M; Howard, G; Shedlofsky, S I; Blouin, R A T32ES007266 J Pharm Pharmacol (2001 Oct) 11697544 Exiting the NIEHS site 2001 
Cloning, heterologous expression, and enzymological characterization of human squalene monooxygenase ...   Laden, B P; Tang, Y; Porter, T D T32ES007266 Arch Biochem Biophys (2000 Feb 15) 10666321 Exiting the NIEHS site 2000 
Effect of PCBs on the activation of the transcription factors AP-1 and NF-kappa B.   Glauert, H P; Tharappel, J C; Lee, E Y; Robertson, L W; Spear, B T P42ES007380, T32ES007266 Cent Eur J Public Health (2000 Jul) 10943439 Exiting the NIEHS site 2000 
Expression of the hydrogen peroxide-generating enzyme fatty acyl CoA oxidase activates NF-kappaB.   Li, Y; Tharappel, J C; Cooper, S; Glenn, M; Glauert, H P; Spear, B T T32ES007266 DNA Cell Biol (2000 Feb) 10701777 Exiting the NIEHS site 2000 
Lobeline inhibits nicotine-evoked [(3)H]dopamine overflow from rat striatal slices and nicotine-evok ...   Miller, D K; Crooks, P A; Dwoskin, L P T32ES007266 Neuropharmacology (2000 Oct) 11044735 Exiting the NIEHS site 2000 
Metabolism and activation of polychlorinated biphenyls (PCBs).   Robertson, L W; Espandiari, P; Lehmler, H J; Pereg, D; Srinivasan, A; Tampal, N; Twaroski, T; ... P42ES007380, T32ES007266 Cent Eur J Public Health (2000 07) 10943437 Exiting the NIEHS site 2000 
Redox cycling of 2-(x'-mono, -di, -trichlorophenyl)- 1, 4-benzoquinones, oxidation products of polyc ...   McLean, M R; Twaroski, T P; Robertson, L W P42ES007380, T32ES007266 Arch Biochem Biophys (2000 Apr 15) 10775433 Exiting the NIEHS site 2000 
Activities of conjugating and antioxidant enzymes following endotoxin exposure.   Watson, A M; Warren, G; Howard, G; Shedlofsky, S I; Blouin, R A T32ES007266 J Biochem Mol Toxicol (1999) 9890190 Exiting the NIEHS site 1999 
Determining efficacy of cancer chemopreventive agents using a cell-free system concomitant with DNA ...   Smith, W A; Gupta, R C T32ES007266 Mutat Res (1999 Mar 10) 10082925 Exiting the NIEHS site 1999 
DNA adduct formation and persistence in rat tissues following exposure to the mammary carcinogen dib ...   Arif, J M; Smith, W A; Gupta, R C T32ES007266 Carcinogenesis (1999 Jun) 10357803 Exiting the NIEHS site 1999 
Pharmacokinetic considerations in obesity.   Blouin, R A; Warren, G W T32ES007266 J Pharm Sci (1999 Jan) 9874695 Exiting the NIEHS site 1999 
S-adenosylmethionine attenuates the lipopolysaccharide-induced expression of the gene for tumour nec ...   Watson, W H; Zhao, Y; Chawla, R K T32ES007266 Biochem J (1999 Aug 15) 10432295 Exiting the NIEHS site 1999 
ATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repair ...   Gu, L; Hong, Y; McCulloch, S; Watanabe, H; Li, G M T32ES007266 Nucleic Acids Res (1998 Mar 01) 9469823 Exiting the NIEHS site 1998 
Effect of cancer chemopreventive agents on microsome-mediated DNA adduction of the breast carcinogen ...   Smith, W A; Arif, J M; Gupta, R C T32ES007266 Mutat Res (1998 Feb 13) 9600699 Exiting the NIEHS site 1998 
The effect of high dose endotoxin on CYP3A2 expression in the rat.   Roe, A L; Warren, G; Hou, G; Howard, G; Shedlofsky, S I; Blouin, R A T32ES007250, T32ES007266 Pharm Res (1998 Oct) 9794504 Exiting the NIEHS site 1998 
Reciprocal size-effect relationship of the key residues in determining regio- and stereospecificitie ...   Uno, T; Mitchell, E; Aida, K; Lambert, M H; Darden, T A; Pedersen, L G; Negishi, M T32ES007266 Biochemistry (1997 Mar 18) 9115996 Exiting the NIEHS site 1997 
Tissue distribution of DNA adducts in rats treated by intramammillary injection with dibenzo[a,l]pyr ...   Arif, J M; Smith, W A; Gupta, R C T32ES007266 Mutat Res (1997 Aug 01) 9288883 Exiting the NIEHS site 1997 
Active transport of cimetidine and ranitidine into the milk of Sprague Dawley rats.   McNamara, P J; Meece, J A; Paxton, E T32ES007266 J Pharmacol Exp Ther (1996 Jun) 8667230 Exiting the NIEHS site 1996 
Aluminum facilitation of iron-mediated lipid peroxidation is dependent on substrate, pH and aluminum ...   Xie, C X; Yokel, R A T32ES007266 Arch Biochem Biophys (1996 Mar 15) 8619606 Exiting the NIEHS site 1996 
Analysis of polychlorinated biphenyl-DNA adducts by 32P-postlabeling.   Oakley, G G; Robertson, L W; Gupta, R C T32ES007266 Carcinogenesis (1996 Jan) 8565118 Exiting the NIEHS site 1996 
High-resolution anion-exchange and partition thin-layer chromatography for complex mixtures of 32P-p ...   Spencer-Beach, G G; Beach, A C; Gupta, R C T32ES007266 J Chromatogr B Biomed Appl (1996 Mar 03) 8704930 Exiting the NIEHS site 1996 
In vivo phenobarbital treatment increases protein binding to a putative AP-1 site in the CYP2B2 prom ...   Roe, A L; Blouin, R A; Howard, G T32ES007266 Biochem Biophys Res Commun (1996 Nov 1) 8912644 Exiting the NIEHS site 1996 
Intraneuronal aluminum potentiates iron-induced oxidative stress in cultured rat hippocampal neurons ...   Xie, C X; Mattson, M P; Lovell, M A; Yokel, R A T32ES007266 Brain Res (1996 Dec 16) 9017255 Exiting the NIEHS site 1996 
Metabolic activation of PCBs to quinones: reactivity toward nitrogen and sulfur nucleophiles and inf ...   Amaro, A R; Oakley, G G; Bauer, U; Spielmann, H P; Robertson, L W T32ES007266 Chem Res Toxicol (1996 Apr-May) 8728508 Exiting the NIEHS site 1996 
Oxidative DNA damage induced by activation of polychlorinated biphenyls (PCBs): implications for PCB ...   Oakley, G G; Devanaboyina, U; Robertson, L W; Gupta, R C T32ES007266 Chem Res Toxicol (1996 Dec) 8951230 Exiting the NIEHS site 1996 
The 3-hydroxypyridin-4-ones more effectively chelate aluminum in a rabbit model of aluminum intoxica ...   Yokel, R A; Meurer, K A; Skinner, T L; Fredenburg, A M T32ES007266 Drug Metab Dispos (1996 Jan) 8825197 Exiting the NIEHS site 1996 
The pharmacokinetics and blood-brain barrier permeation of the chelators 1,2 dimethly-, 1,2 diethyl- ...   Fredenburg, A M; Sethi, R K; Allen, D D; Yokel, R A T32ES007266 Toxicology (1996 Apr 30) 8658538 Exiting the NIEHS site 1996 
A new strategy for the synthesis of polychlorinated biphenyl metabolites.   Bauer, U; Amaro, A R; Robertson, L W T32ES007266 Chem Res Toxicol (1995 Jan-Feb) 7703372 Exiting the NIEHS site 1995 
Effect of dietary retinyl palmitate on the promotion of altered hepatic foci by 3,3',4,4'-tetrachlor ...   Berberian, I; Chen, L C; Robinson, F R; Glauert, H P; Chow, C K; Robertson, L W T32ES007266 Carcinogenesis (1995 Feb) 7859372 Exiting the NIEHS site 1995 
DNA adducts of the ubiquitous environmental contaminant cyclopenta[cd]pyrene.   Beach, A C; Gupta, R C T32ES007266 Carcinogenesis (1994 May) 8200070 Exiting the NIEHS site 1994 
Immunoassay detection of drugs in racing horses: detection of ethacrynic acid and bumetanide in equi ...   Stanley, S; Wood, T; Goodman, J P; Henry, P A; Woods, W E; Chang, S L; Tai, H H; Watt, D; Kw ... T32ES007266 J Anal Toxicol (1994 Mar-Apr) 8207941 Exiting the NIEHS site 1994 
Comparison of Artemia feeding regimens on larval growth in a short-term fathead minnow toxicity test ...   Silberhorn, E M; Robison, W A; Short, T M; Black, J A; Birge, W J T32ES007266 Bull Environ Contam Toxicol (1993 Feb) 8422520 Exiting the NIEHS site 1993 
Differential cytotoxicity of buthionine sulfoximine to "normal" and transformed human lung fibroblas ...   Wan, X S; St Clair, D K T32ES007266 Cancer Chemother Pharmacol (1993) 8269602 Exiting the NIEHS site 1993 
HgEDTA complex inhibits GTP interactions with the E-site of brain beta-tubulin.   Duhr, E F; Pendergrass, J C; Slevin, J T; Haley, B E T32ES007266 Toxicol Appl Pharmacol (1993 Oct) 8212009 Exiting the NIEHS site 1993 
Improved thin-layer chromatographic separation of 32P-postlabeled DNA adducts.   Spencer, G G; Beach, A C; Gupta, R C T32ES007266 J Chromatogr (1993 Feb 26) 8468388 Exiting the NIEHS site 1993 
Perfluorodecanoic acid noncompetitively inhibits the peroxisomal enzymes enoyl-CoA hydratase and 3-h ...   Borges, T; Glauert, H P; Robertson, L W T32ES007266 Toxicol Appl Pharmacol (1993 Jan) 8430427 Exiting the NIEHS site 1993 
Reaction of cyclopenta[c,d]pyrene-3,4-epoxide with DNA and deoxynucleotides.   Beach, A C; Agarwal, S C; Lambert, G R; Nesnow, S; Gupta, R C T32ES007266 Carcinogenesis (1993 Apr) 8472345 Exiting the NIEHS site 1993 
Dose-related effects of perfluorodecanoic acid on growth, feed intake and hepatic peroxisomal beta-o ...   Borges, T; Robertson, L W; Peterson, R E; Glauert, H P T32ES007266 Arch Toxicol (1992) 1580792 Exiting the NIEHS site 1992 
Effects of the peroxisome proliferators ciprofibrate and perfluorodecanoic acid on hepatic cellular ...   Glauert, H P; Srinivasan, S; Tatum, V L; Chen, L C; Saxon, D M; Lay, L T; Borges, T; Baker, ... T32ES007266 Biochem Pharmacol (1992 Mar 17) 1562286 Exiting the NIEHS site 1992 
Human biomonitoring and the 32P-postlabeling assay.   Beach, A C; Gupta, R C T32ES007266 Carcinogenesis (1992 Jul) 1638670 Exiting the NIEHS site 1992 
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