| Project Title: | MEASURING GENOMIC DNA DAMAGE AND DNA REPAIR CAPACITY IN LONGITUDINAL POPULATION SAMPLES - A STEP TOWARDS PRECISION PREVENTION |
|---|---|
| PI: | Sobol, Robert W |
| Institution: | Brown University |
| Grant Number: | U01ES029518 |
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Viewing 18 publications
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| Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
|---|---|---|---|---|---|
| Impact of polβ/XRCC1 Interaction Variants on the Efficiency of Nick Sealing by DNA Ligase IIIα in th ... | Almohdar, Danah; Gulkis, Mitchell; Ortiz, Abigail; Tang, Qun; Sobol, Robert W; Çağlayan, Melik ... | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | J Mol Biol (2024 Feb 15) |
38135179
|
2024 |
| Mouse models to explore the biological and organismic role of DNA polymerase beta. | Sobol, Robert W | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | Environ Mol Mutagen (2024 Apr) |
38619421
|
2024 |
| A multi-scale map of protein assemblies in the DNA damage response. | Kratz, Anton; Kim, Minkyu; Kelly, Marcus R; Zheng, Fan; Koczor, Christopher A; Li, Jianfeng; O ... | U01ES029518, U01ES029518 | Cell Syst (2023 Jun 21) |
37220749
|
2023 |
| A New Drug Discovery Platform: Application to DNA Polymerase Eta and Apurinic/Apyrimidinic Endonucle ... | Das, Debanu; Duncton, Matthew A J; Georgiadis, Taxiarchis M; Pellicena, Patricia; Clark, Jennif ... | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | Int J Mol Sci (2023 Nov 23) |
38068959
|
2023 |
| Editorial: DNA repair and nucleic acid therapeutics in cancer. | Sobol, Robert W | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | NAR Cancer (2023 Sep) |
37645072
|
2023 |
| Overexpression of the WWE domain of RNF146 modulates poly-(ADP)-ribose dynamics at sites of DNA dama ... | Al-Rahahleh, Rasha Q; Saville, Kate M; Andrews, Joel F; Wu, Zhijin; Koczor, Christopher A; Sobo ... | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | bioRxiv (2023 Dec 29) |
38234836
|
2023 |
| Polβ/XRCC1 heterodimerization dictates DNA damage recognition and basal Polβ protein levels without ... | Koczor, Christopher A; Thompson, Marlo K; Sharma, Nidhi; Prakash, Aishwarya; Sobol, Robert W | P01ES028949, R01ES030084, R44ES032522, U01ES029518, U01ES029518 | DNA Repair (Amst) (2023 Mar) |
36702010
|
2023 |
| Quantitative Analysis of Nuclear Poly(ADP-Ribose) Dynamics in Response to Laser-Induced DNA Damage. | Koczor, Christopher A; Saville, Kate M; Al-Rahahleh, Rasha Q; Andrews, Joel F; Li, Jianfeng; So ... | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | Methods Mol Biol (2023) |
36515828
|
2023 |
| WRN suppresses p53/PUMA-induced apoptosis in colorectal cancer with microsatellite instability/misma ... | Sobol, Robert W | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | Proc Natl Acad Sci U S A (2023 Jan 10) |
36598947
|
2023 |
| A high-throughput 384-well CometChip platform reveals a role for 3-methyladenine in the cellular res ... | Li, Jianfeng; Beiser, Alison; Dey, Nupur B; Takeda, Shunichi; Saha, Liton Kumar; Hirota, Kouji ... | R44ES032522, U01ES029518, U01ES029518 | NAR Genom Bioinform (2022 Sep) |
36110898
|
2022 |
| Double-strand breaks: When DNA repair events accidentally meet. | Fujii, Shingo; Sobol, Robert W; Fuchs, Robert P | P01ES028949, U01ES029518, U01ES029518 | DNA Repair (Amst) (2022 Apr) |
35219626
|
2022 |
| Exploiting DNA Endonucleases to Advance Mechanisms of DNA Repair. | Thompson, Marlo K; Sobol, Robert W; Prakash, Aishwarya | P01ES028949, R01ES030084, R44ES032522, U01ES029518, U01ES029518 | Biology (Basel) (2021 Jun 14) |
34198612
|
2021 |
| NAD+ bioavailability mediates PARG inhibition-induced replication arrest, intra S-phase checkpoint a ... | Li, Jianfeng; M Saville, Kate; Ibrahim, Md; Zeng, Xuemei; McClellan, Steve; Angajala, Anusha; ... | U01ES029518, U01ES029518 | NAR Cancer (2021 Dec) |
34806016
|
2021 |
| Primary saturation of α, β-unsaturated carbonyl containing fatty acids does not abolish electrophili ... | Snyder, Nathaniel W; O'Brien, James; Singh, Bhupinder; Buchan, Gregory; Arroyo, Alejandro D; Li ... | P01ES028949, P30ES013508, R44ES032522, U01ES029518, U01ES029518 | Chem Biol Interact (2021 Dec 01) |
34634267
|
2021 |
| Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly a ... | Koczor, Christopher A; Saville, Kate M; Andrews, Joel F; Clark, Jennifer; Fang, Qingming; Li, ... | P01ES028949, U01ES029518, U01ES029518 | Cell Rep (2021 11 02) |
34731617
|
2021 |
| Extracellular NAD+ enhances PARP-dependent DNA repair capacity independently of CD73 activity. | Wilk, Anna; Hayat, Faisal; Cunningham, Richard; Li, Jianfeng; Garavaglia, Silvia; Zamani, Leil ... | U01ES029518, U01ES029518 | Sci Rep (2020 01 20) |
31959836
|
2020 |
| NAD+-mediated regulation of mammalian base excision repair. | Saville, Kate M; Clark, Jennifer; Wilk, Anna; Rogers, Gresyn D; Andrews, Joel F; Koczor, Chris ... | P01ES028949, U01ES029518, U01ES029518 | DNA Repair (Amst) (2020 09) |
33087267
|
2020 |
| Mechanisms of MTH1 inhibition-induced DNA strand breaks: The slippery slope from the oxidized nucleo ... | Rai, Priyamvada; Sobol, Robert W | P01ES028949, U01ES029518, U01ES029518 | DNA Repair (Amst) (2019 05) |
30852368
|
2019 |