Title: Transport of conjugates of toxicants by blood proteins.
Authors: Shah, P V; Helling, D J; Maliwal, B P; Guthrie, F E
Published In Toxicol Lett, (1985 Feb-Mar)
Abstract: Binding of naphthol and its glucoside and glucuronide conjugates by blood proteins was studied in vitro and in vivo. Binding was found to be primarily to the albumin fraction of human blood and the binding constants were moderate to low. Both in vivo (mice) and in vitro (human) experiments suggest that a substantial portion of naphthol and two conjugates are transported in bound form to the site of elimination.
PubMed ID: 3983972
MeSH Terms: No MeSH terms associated with this publication