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Title: Occupational exposure to dibutyl phthalate among manicurists.

Authors: Kwapniewski, Rachel; Kozaczka, Sarah; Hauser, Russ; Silva, Manori J; Calafat, Antonia M; Duty, Susan M

Published In J Occup Environ Med, (2008 Jun)

Abstract: To measure manicurists' exposure to dibutyl phthalate (DBP) at work and to determine whether workplace characteristics influence this exposure. DBP is a reproductive and developmental toxicant in rats and is used in nail polish to hold color and prevent chipping.Pre- and postshift spot urine samples were collected from 40 manicurists. Linear regression compared the relationship between the log of the cross-shift differences in urinary phthalate monoester metabolite concentrations and use of workplace exposure control methods.There was a statistically significant cross-shift increase of 17.4 ng/mL in the urinary concentration of mono-n-butyl phthalate, the major metabolite of DBP. Use of gloves reduced mono-n-butyl phthalate concentrations by 15.1 ng/mL below the preshift concentration compared with a 20.5 ng/mL increase if gloves were not worn.Manicurists are occupationally exposed to DBP and glove use may minimize this exposure.

PubMed ID: 18545098 Exiting the NIEHS site

MeSH Terms: Adult; Air Pollutants, Occupational/analysis*; Beauty Culture*; Dibutyl Phthalate/analysis*; Dibutyl Phthalate/urine; Environmental Monitoring/statistics & numerical data*; Gloves, Protective/utilization; Humans; Occupational Exposure/analysis*; Plasticizers/analysis*; Protective Clothing; Ventilation

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