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Title: Occupational factors and risk of Parkinson's disease: A population-based case-control study.

Authors: Firestone, Jordan A; Lundin, Jessica I; Powers, Karen M; Smith-Weller, Terri; Franklin, Gary M; Swanson, Phillip D; Longstreth Jr, W T; Checkoway, Harvey

Published In Am J Ind Med, (2010 Mar)

Abstract: Parkinson's disease (PD) has been associated with various workplace factors, but the evidence is inconsistent.To estimate the risk of PD associated with various jobs and workplace exposures.We conducted a population-based, case-control study of 404 incident PD cases and 526 age and sex-matched controls, collecting self-reported work histories including job titles and exposures to various industrial toxicants. Relative risks of PD from these exposures were estimated with odds ratios (OR) and 95% confidence intervals (CI) using logistic regression.Risk was not significantly affected by farming work, by metal work, or by exposure to pesticides, metals, or solvents.These findings do not provide support for the hypothesis that workplace factors affect the risk of PD.

PubMed ID: 20025075 Exiting the NIEHS site

MeSH Terms: Adult; Aged; Aged, 80 and over; Case-Control Studies; Confidence Intervals; Female; Hazardous Substances/toxicity; Humans; Incidence; Industry/classification; Male; Middle Aged; Occupational Diseases/epidemiology; Occupational Diseases/etiology*; Occupational Exposure/adverse effects*; Odds Ratio; Parkinson Disease/epidemiology; Parkinson Disease/etiology*; Pesticides/adverse effects; Risk Assessment; Risk Factors; Surveys and Questionnaires; Washington/epidemiology; Workplace

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