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Publication Detail

Title: Chromium and genomic stability.

Authors: Wise, Sandra S; Wise Sr, John Pierce

Published In Mutat Res, (2012 May 01)

Abstract: Many metals serve as micronutrients which protect against genomic instability. Chromium is most abundant in its trivalent and hexavalent forms. Trivalent chromium has historically been considered an essential element, though recent data indicate that while it can have pharmacological effects and value, it is not essential. There is no data indicating that trivalent chromium promotes genomic stability and, instead may promote genomic instability. Hexavalent chromium is widely accepted as highly toxic and carcinogenic with no nutritional value. Recent data indicate that it causes genomic instability and also has no role in promoting genomic stability.

PubMed ID: 22192535 Exiting the NIEHS site

MeSH Terms: Carcinogens/toxicity*; Chromium/physiology*; Chromium/toxicity; Genomic Instability/drug effects*; Humans; Nutritive Value

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