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Publication Detail

Title: Arsenic exposure and oral cavity lesions in Bangladesh.

Authors: Syed, Emdadul H; Melkonian, Stephanie; Poudel, Krishna C; Yasuoka, Junko; Otsuka, Keiko; Ahmed, Alauddin; Islam, Tariqul; Parvez, Faruque; Slavkovich, Vesna; Graziano, Joseph H; Ahsan, Habibul; Jimba, Masamine

Published In J Occup Environ Med, (2013 Jan)

Abstract: To evaluate the relationship between arsenic exposure and oral cavity lesions among an arsenic-exposed population in Bangladesh.We carried out an analysis utilizing the baseline data of the Health Effects of Arsenic Exposure Longitudinal Study, which is an ongoing population-based cohort study to investigate health outcomes associated with arsenic exposure via drinking water in Araihazar, Bangladesh. We used multinomial regression models to estimate the risk of oral cavity lesions.Participants with high urinary arsenic levels (286.1 to 5000.0 μg/g) were more likely to develop arsenical lesions of the gums (multinomial odds ratio = 2.90; 95% confidence interval, 1.11 to 7.54), and tongue (multinomial odds ratio = 2.79; 95% confidence interval, 1.51 to 5.15), compared with those with urinary arsenic levels of 7.0 to 134.0 μg/g.Higher level of arsenic exposure was positively associated with increased arsenical lesions of the gums and tongue.

PubMed ID: 23201591 Exiting the NIEHS site

MeSH Terms: Adult; Arsenic/adverse effects*; Arsenic/urine; Bangladesh/epidemiology; Confidence Intervals; Cross-Sectional Studies; Databases, Factual; Drinking Water; Environmental Exposure/adverse effects; Female; Humans; Incidence; Life Style; Male; Middle Aged; Mouth Diseases/chemically induced; Mouth Diseases/epidemiology; Mouth Diseases/pathology; Mouth Mucosa/pathology; Multivariate Analysis; Odds Ratio; Prognosis; Regression Analysis; Risk Assessment; Severity of Illness Index; Socioeconomic Factors; Stomatitis/chemically induced*; Stomatitis/epidemiology; Stomatitis/pathology; Tongue Diseases/chemically induced*; Tongue Diseases/epidemiology; Tongue Diseases/pathology; Water Pollutants, Chemical/adverse effects*

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