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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Publication Detail

Title: Inverse association between toenail arsenic and body mass index in a population of welders.

Authors: Grashow, Rachel; Zhang, Jinming; Fang, Shona C; Weisskopf, Marc G; Christiani, David C; Kile, Molly L; Cavallari, Jennifer M

Published In Environ Res, (2014 May)

Abstract: Recent data show that arsenic may play a role in obesity-related diseases. However, urinary arsenic studies report an inverse association between arsenic level and body mass index (BMI). We explored whether toenail arsenic, a long-term exposure measure, was associated with BMI in 74 welders with known arsenic exposure. BMI showed significant inverse associations with toenail arsenic (p=0.01), which persisted in models adjusted for demographics, diet and work history. It is unclear whether low arsenic biomarker concentrations in high BMI subjects truly reflect lower exposures, or instead reflect internal or metabolic changes that alter arsenic metabolism and tissue deposition.

PubMed ID: 24721130 Exiting the NIEHS site

MeSH Terms: No MeSH terms associated with this publication

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