Title: Functional chromatographic technique for natural product isolation.
Authors: Lau, Eric C; Mason, Damian J; Eichhorst, Nicole; Engelder, Pearce; Mesa, Celestina; Kithsiri Wijeratne, E M; Gunaherath, G M Kamal B; Gunatilaka, A A Leslie; La Clair, James J; Chapman, Eli
Published In Org Biomol Chem, (2015 Feb 28)
Abstract: Natural product discovery arises through a unique interplay between chromatographic purification and biological assays. Currently, most techniques used for natural product purification deliver leads without a defined biological action. We now describe a technique, referred to herein as functional chromatography, that deploys biological affinity as the matrix for compound isolation.
PubMed ID: 25588099
MeSH Terms: No MeSH terms associated with this publication