Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

National Institute of Environmental Health Sciences

Use this QR code to view the newest version of this document
Use this QR code to view the newest version of this document

Your Environment. Your Health.

Publication Detail

Title: In Vivo Delivery of Nitric Oxide-Sensing, Single-Walled Carbon Nanotubes.

Authors: Iverson, Nicole M; Strano, Michael S; Wogan, Gerald N

Published In Curr Protoc Chem Biol, (2015 Jun 01)

Abstract: Detection of nitric oxide (NO) in vivo by single-walled carbon nanotubes (SWNT) is based on the fluorescent properties of SWNT and the ability of NO to quench the fluorescence signal. Alterations of the signal can be utilized to detect a small molecule in vivo that has not previously been possible by other assay techniques. The protocols described here explain the techniques used to prepare NO-detecting SWNTs and to administer them to mice by both intravenous and subcutaneous routes. These techniques can also be utilized with other SWNT sensors as well as non-SWNT sensors.

PubMed ID: 26344235 Exiting the NIEHS site

MeSH Terms: Animals; Biosensing Techniques*; Fluorescence; Mice; Nanotubes, Carbon/chemistry*; Nitric Oxide/chemistry*

Back
to Top