Title: Promoting metastasis: neutrophils and T cells join forces.
Authors: Fridlender, Zvi G; Albelda, Steven M; Granot, Zvi
Published In Cell Res, (2015 Jul)
Abstract: The role neutrophils play in cancer is a matter of debate as both pro- and anti-tumor functions have been documented. In a recent publication in Nature, Coffelt et al. identify a new mechanism where neutrophils and T cells cooperate to generate metastasis-supporting immune suppression.
PubMed ID: 26138787
MeSH Terms: Animals; Breast Neoplasms/pathology*; Female; Interleukin-17/biosynthesis*; Neoplasm Metastasis/immunology*; Neoplasm Metastasis/pathology*; Neutrophils/metabolism*; T-Lymphocyte Subsets/metabolism*