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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Publication Detail

Title: Strategies for Genomic and Proteomic Profiling of Cancers.

Authors: Omenn, Gilbert S

Published In Stat Biosci, (2016 Jun)

Abstract: Omics-based technology platforms have made new kinds of cancer profiling tests feasible. There are several valuable examples in clinical practice, and many more under development. A concerted, transparent process of discovery with lock-down of candidate assays and classifiers and clear specification of intended clinical use is essential. The Institute of Medicine has now proposed a three-stage scheme of confirming and validating analytical findings, validating performance on clinical specimens, and demonstrating explicit clinical utility for an approvable test (Micheel et al., Evolution of translational omics: lessons learned and path forward, 2012).

PubMed ID: 27594925 Exiting the NIEHS site

MeSH Terms: No MeSH terms associated with this publication

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