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Publication Detail

Title: Potential Risk Factors for the Development of Self-Injurious Behavior among Infants at Risk for Autism Spectrum Disorder.

Authors: Dimian, Adele F; Botteron, Kelly N; Dager, Stephen R; Elison, Jed T; Estes, Annette M; Pruett Jr, John R; Schultz, Robert T; Zwaigenbaum, Lonnie; Piven, Joseph; Wolff, Jason J; IBIS Network

Published In J Autism Dev Disord, (2017 May)

Abstract: Prevalence of self-injurious behavior (SIB) is as high as 50% among children with autism spectrum disorder (ASD). Identification of risk factors for the development of SIB is critical to early intervention and prevention. However, there is little empirical research utilizing a prospective design to identify early risk factors for SIB. The purpose of this study was to evaluate behavioral characteristics predicting SIB at age 2 years among 235 infants at high familial risk for ASD. Logistic regression results indicated that presence of SIB or proto-SIB and lower developmental functioning at age 12 months significantly predicted SIB at 24 months. A pattern of persistent SIB over this period was associated with a diagnosis of autism and poorer cognitive and adaptive outcomes.

PubMed ID: 28220358 Exiting the NIEHS site

MeSH Terms: No MeSH terms associated with this publication

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