Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Your Environment. Your Health.

Publication Detail

Title: Autoimmunity, Autoantibodies, and Autism Spectrum Disorder.

Authors: Edmiston, Elizabeth; Ashwood, Paul; Van de Water, Judy

Published In Biol Psychiatry, (2017 03 01)

Abstract: Auism spectrum disorder (ASD) now affects one in 68 births in the United States and is the fastest growing neurodevelopmental disability worldwide. Alarmingly, for the majority of cases, the causes of ASD are largely unknown, but it is becoming increasingly accepted that ASD is no longer defined simply as a behavioral disorder, but rather as a highly complex and heterogeneous biological disorder. Although research has focused on the identification of genetic abnormalities, emerging studies increasingly suggest that immune dysfunction is a viable risk factor contributing to the neurodevelopmental deficits observed in ASD. This review summarizes the investigations implicating autoimmunity and autoantibodies in ASD.

PubMed ID: 28340985 Exiting the NIEHS site

MeSH Terms: Animals; Autism Spectrum Disorder/genetics; Autism Spectrum Disorder/immunology*; Autoantibodies/immunology*; Autoimmunity*; Brain/immunology; Disease Models, Animal; Female; Humans; Macaca mulatta; Maternal-Fetal Exchange; Pregnancy; Risk Factors

Back
to Top