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National Institute of Environmental Health Sciences

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Publication Detail

Title: Organic and inorganic transporters of the testis: A review.

Authors: Klein, David M; Cherrington, Nathan J

Published In Spermatogenesis, (2014 May-Aug)

Abstract: Transporters have a huge impact on the toxicology and pharmacological effects of xenobiotics in addition to being implicated in several diseases. While these important proteins have been well studied in organs such as the kidney or liver, characterization of transporters in the testis is still in the early stages. Knowledge of transporter function may greatly advance the field's understanding of the physiological and toxicological processes that occur in the testis. Several foundational studies involving both organic and inorganic transporters have been critical in furthering our understanding of how the testis interacts with endogenous and xenobiotic compounds. This review provides an overview of how transporters function, their clinical significance, and highlights what is known for many of the important transporters in the testis.

PubMed ID: 26413398 Exiting the NIEHS site

MeSH Terms: No MeSH terms associated with this publication

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