Title: Molecular mechanisms and genomic maps of DNA excision repair in Escherichia coli and humans.
Authors: Hu, Jinchuan; Selby, Christopher P; Adar, Sheera; Adebali, Ogun; Sancar, Aziz
Published In J Biol Chem, (2017 09 22)
Abstract: Nucleotide excision repair is a major DNA repair mechanism in all cellular organisms. In this repair system, the DNA damage is removed by concerted dual incisions bracketing the damage and at a precise distance from the damage. Here, we review the basic mechanisms of excision repair in Escherichia coli and humans and the recent genome-wide mapping of DNA damage and repair in these organisms at single-nucleotide resolution.
PubMed ID: 28798238
MeSH Terms: Chromosome Mapping/methods*; DNA Damage; DNA Repair/genetics*; Escherichia coli/genetics*; Humans