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Title: Air pollution, cardiovascular endpoints and susceptibility by stress and material resources: a systematic review of the evidence.

Authors: Fuller, Christina H; Feeser, Karla R; Sarnat, Jeremy A; O'Neill, Marie S

Published In Environ Health, (2017 Jun 14)

Abstract: Evidence shows that both the physical and social environments play a role in the development of cardiovascular disease. The purpose of this systematic review is two-fold: First, we summarize research from the past 12 years from the growing number of studies focused on effect modification of the relationships between air pollution and cardiovascular disease (CVD) outcomes by socioeconomic position (SEP) and; second, we identify research gaps throughout the published literature on this topic and opportunities for addressing these gaps in future study designs.We identified 30 articles that examined the modifying effects of either material resources or psychosocial stress (both related to SEP) on associations between short and long-term air pollution exposure and CVD endpoints. Although 18 articles identified at least one interaction between an air pollutant and material resource indicator, 11 others did not. Support for susceptibility to air pollution by psychosocial stress was weaker; however, only three articles tested this hypothesis. Further studies are warranted to investigate how air pollution and SEP together may influence CVD.We recommend that such research include thorough assessment of air pollution and SEP correlations, including spatial correlation; investigate air pollution indices or multi-pollutant models; use standardized metrics of SEP to enhance comparability across studies; and evaluate potentially susceptible populations.

PubMed ID: 28615066 Exiting the NIEHS site

MeSH Terms: Air Pollutants/adverse effects; Air Pollution/adverse effects*; Cardiovascular Diseases/chemically induced; Cardiovascular Diseases/epidemiology*; Disease Susceptibility/chemically induced; Disease Susceptibility/epidemiology*; Environmental Exposure*; Prevalence; Social Class*; Stress, Physiological*

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