Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

National Institute of Environmental Health Sciences

Use this QR code to view the newest version of this document
Use this QR code to view the newest version of this document

Your Environment. Your Health.

Publication Detail

Title: xMWAS: a data-driven integration and differential network analysis tool.

Authors: Uppal, Karan; Ma, Chunyu; Go, Young-Mi; Jones, Dean P; Wren, Jonathan

Published In Bioinformatics, (2018 Feb 15)

Abstract: Integrative omics is a central component of most systems biology studies. Computational methods are required for extracting meaningful relationships across different omics layers. Various tools have been developed to facilitate integration of paired heterogenous omics data; however most existing tools allow integration of only two omics datasets. Furthermore, existing data integration tools do not incorporate additional steps of identifying sub-networks or communities of highly connected entities and evaluating the topology of the integrative network under different conditions. Here we present xMWAS, a software for data integration, network visualization, clustering, and differential network analysis of data from biochemical and phenotypic assays, and two or more omics platforms.https://kuppal.shinyapps.io/xmwas (Online) and https://github.com/kuppal2/xMWAS/ (R).kuppal2@emory.edu.Supplementary data are available at Bioinformatics online.

PubMed ID: 29069296 Exiting the NIEHS site

MeSH Terms: No MeSH terms associated with this publication

Back
to Top