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Publication Detail

Title: Ovarian and Extra-Ovarian Mediators in the Development of Polycystic Ovary Syndrome.

Authors: Puttabyatappa, Muraly; Padmanabhan, Vasantha

Published In J Mol Endocrinol, (2018 10 16)

Abstract: Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder affecting women of reproductive age. The origin of PCOS is still not clear and appears to be a function of gene x environment interactions. This review addresses the current knowledge of the genetic and developmental contributions to the etiology of PCOS, the ovarian and extra-ovarian mediators of PCOS and the gaps and key challenges that need to be addressed in the diagnosis, treatment and prevention of PCOS.

PubMed ID: 29941488 Exiting the NIEHS site

MeSH Terms: Animals; Female; Granulosa Cells/metabolism; Humans; Insulin/metabolism; Ovary/cytology; Ovary/metabolism*; Ovary/pathology; Polycystic Ovary Syndrome/metabolism*

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