Title: How autophagy is tied to inflammation and cancer.
Authors: Zhu, Qing; Wang, Ruifang; Nemecio, Dali; Liang, Chengyu
Published In Mol Cell Oncol, (2020)
Abstract: It is not completely understood how autophagy is tied to inflammation and age-related cancer predisposition. Here, we used a mouse model with inducible expression of a cancer-derived frameshift mutation in UV radiation resistance associated (UVRAG) to demonstrate that intervention with autophagy suppressor could exacerbate inflammation and promote age-related spontaneous cancers.
PubMed ID: 32158928
MeSH Terms: No MeSH terms associated with this publication