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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Publication Detail

Title: How autophagy is tied to inflammation and cancer.

Authors: Zhu, Qing; Wang, Ruifang; Nemecio, Dali; Liang, Chengyu

Published In Mol Cell Oncol, (2020)

Abstract: It is not completely understood how autophagy is tied to inflammation and age-related cancer predisposition. Here, we used a mouse model with inducible expression of a cancer-derived frameshift mutation in UV radiation resistance associated (UVRAG) to demonstrate that intervention with autophagy suppressor could exacerbate inflammation and promote age-related spontaneous cancers.

PubMed ID: 32158928 Exiting the NIEHS site

MeSH Terms: No MeSH terms associated with this publication

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