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Publication Detail

Title: Public data sources to support systems toxicology applications.

Authors: Davis, Allan Peter; Wiegers, Jolene; Wiegers, Thomas C; Mattingly, Carolyn J

Published In Curr Opin Toxicol, (2019 Aug)

Abstract: Public databases provide a wealth of freely available information about chemicals, genes, proteins, biological networks, phenotypes, diseases, and exposure science that can be integrated to construct pathways for systems toxicology applications. Relating this disparate information from public repositories, however, can be challenging since databases use a variety of ways to represent, describe, and make available their content. The use of standard vocabularies to annotate key data concepts, however, allows the information to be more easily exchanged and combined for discovery of new findings. We explore some of the many public data sources currently available to support systems toxicology, and demonstrate the value of standardizing data to help construct chemical-induced outcome pathways.

PubMed ID: 33604492 Exiting the NIEHS site

MeSH Terms: No MeSH terms associated with this publication

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