Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Your Environment. Your Health.

Publication Detail

Title: Exhaled nitric oxide: sources of error in offline measurement.

Authors: Linn, William S; Avila, Marisela; Gong Jr, Henry

Published In Arch Environ Health, (2004 Aug)

Abstract: Delayed offline measurement of exhaled nitric oxide (eNO), although useful in environmental and clinical research, is limited by the instability of stored breath samples. The authors characterized sources of instability with the goal of minimizing them. Breath and other air samples were stored under various conditions, and NO levels were measured repeatedly over 1-7 d. Concentration change rates varied positively with temperature and negatively with initial NO level, thus "stable" levels reflected a balance of NO-adding and NO-removing processes. Storage under refrigeration for a standardized period of time can optimize offline eNO measurement, although samples at room temperature are effectively stable for several hours.

PubMed ID: 16268114 Exiting the NIEHS site

MeSH Terms: Adolescent; Adult; Breath Tests; Child; Female; Humans; Lung Diseases/diagnosis*; Male; Nitric Oxide/analysis*; Reproducibility of Results; Specimen Handling; Temperature; Time Factors

Back
to Top