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Publication Detail

Title: Uranium mining and lung cancer among Navajo men in New Mexico and Arizona, 1969 to 1993.

Authors: Gilliland, F D; Hunt, W C; Pardilla, M; Key, C R

Published In J Occup Environ Med, (2000 Mar)

Abstract: Navajo men who were underground miners have excess risk of lung cancer. To further characterize the long-term consequences of uranium mining in this high-risk population, we examined lung cancer incidence among Navajo men residing in New Mexico and Arizona from 1969 to 1993 and conducted a population-based case-control study to estimate the risk of lung cancer for Navajo uranium miners. Uranium mining contributed substantially to lung cancer among Navajo men over the 25-year period following the end of mining for the Navajo Nation. Sixty-three (67%) of the 94-incident lung cancers among Navajo men occurred in former uranium miners. The relative risk for a history of mining was 28.6 (95% confidence interval, 13.2-61.7). Smoking did not account for the strong relationship between lung cancer and uranium mining. The Navajo experience with uranium mining is a unique example of exposure in a single occupation accounting for the majority of lung cancers in an entire population.

PubMed ID: 10738707 Exiting the NIEHS site

MeSH Terms: Adult; Age Distribution; Aged; Arizona/epidemiology; Case-Control Studies; Confidence Intervals; Humans; Incidence; Indians, North American/statistics & numerical data*; Lung Neoplasms/epidemiology*; Lung Neoplasms/etiology; Male; Middle Aged; Mining/statistics & numerical data*; New Mexico/epidemiology; Occupational Exposure/analysis*; Reference Values; Registries; Risk Factors; Survival Rate; Uranium/adverse effects*; Uranium/analysis

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